Cystic Fibrosis impacts approximately 1 in every 3,500 births, with around 70,000 affected individuals globally, and 31,000 in the United States alone. Those with the condition experience the devel...
Audiology Devices have witnessed an unprecedented surge in demand in recent years. One of the primary drivers is the escalating prevalence of hearing impairments globally, attributed to various factors such as an aging population and increased exposure to environmental noise. As per the World Health Organization (W...
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The KRAS G12C mutation obstructs the binding of GAP to KRAS, preventing GTP hydrolysis and keeping G12C-mutant KRAS continuously active. This sustained activation triggers the MAPK and PI3K signaling pathways, fueling the formation of tumors. Drugs like sotorasib and adagrasib directly target KRAS G12C by forming a...
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Ionis Pharmaceuticals and AstraZeneca concluded the year 2023 on a positive note as they received the eagerly awaited approval from the FDA for their transthyretin amyloidosis (ATTR) medication, Wainua. In particular, the agency approved the use of the ligand-conjugated antisense oligonucleotide (LICA) medication f...
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DNA Sequencing stands as a cornerstone technology, revolutionizing the landscape of biological sciences and the healthcare market outlook. This groundbreaking technology has evolved significantly over the years, transforming from a time-consuming and costly procedure into a high-throughput, efficient, and cost-effe...
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T-cell receptor (TCR)-dependent treatment involves modified immune cells aimed at attacking particular tumor indicators. This treatment approach necessitates a systematic procedure including patient evaluation (e.g., for HLA-A*02:01 and precise tumor markers), collecting immune cells, creating the altered TCR produ...
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Hematopoietic progenitor kinase (HPK1) belongs to the family of Ste20 serine/threonine kinases known as mitogen-activated protein kinase kinase kinase kinase (MAP4K). It is primarily expressed in hematopoietic cells and functions as a negative regulator of T-cell receptor (TCR) and B-cell signaling, serving as an i...
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The escalating burden of blood cancer presents a pressing global health concern, with its incidence rising steadily. This surge is attributed to various factors, including an aging population, lifestyle changes, and environmental influences. However, amidst this challenge, advancements in Blood Cancer Diagnostics D...
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Prediabetes is a significant health concern characterized by elevated blood sugar levels that fall between the normal range and the diagnostic threshold for type 2 diabetes. Often labeled as borderline diabetes, this metabolic condition is intricately linked to the global rise in obesity and poses an escalating wor...
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In recent years, the misuse and abuse of opioids have become a growing concern worldwide, with devastating consequences for public health. While the immediate dangers of opioid overdose are well-documented, a silent and potentially lethal complication often lurks in the shadows—opioid-induced respiratory depression...
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Wearable technology has been gaining momentum for the last few years as an effect of the fourth indu.....
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HIV-associated lipodystrophy (HAL), is a condition characterized by the redistribution of adipose ti.....
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An inherited disorder, Von Hippel-Lindau (VHL) syndrome is characterized by the formation of tumors .....
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Real-world evidence (RWE) is used in an exponential way to guide payment decisions and access system.....
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Schizophrenia is a severe mental illness that interferes with a person's ability to think clearly, m.....
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Systemic scleroderma (SSC or systemic sclerosis) is an autoimmune disorder that results into scar ti.....
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The American Society of Clinical Oncology (ASCO) is one of the largest and most respected conferences in the field of oncology. Held annually, this conference brings together researchers, physicians, and other healthcare professionals from around the world to discuss the latest advances in cancer research, diagnosis, and treatment.
