Toll-like receptors

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Role of TLR7/8 Agonists in Treating Various Cancers

The Toll family of receptors includes several related proteins involved in plant and animal development and defense. Mammalian TLRs are a large family with at least 11 members, of which humans encode the first ten. Individual TLRs are critical in recognizing pathogen-derived microbial components such as bacteria, f...

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Eli Lilly’s COVID-19 Antibody trial; Approval for Oriahnn; Gilead’s Remdesivir Clinical Trials result; Russia approves Avifavir to treat Covid-19

Eli Lilly and AbCellera announced the dosing of the patients suffering from COVID-19 with antibody candidate - LY-CoV555.  LY-CoV555 is a neutralizing IgG1 monoclonal antibody (mAb) that targets the spikes of the proteins of SARS-CoV-2. So far, COVID-19 has taken the lives of more than 372,000 people g...

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Toll-Like Receptor Modulators: Emerging therapy for many indications

Toll-like receptors are a family of various related proteins that play a major role in the development and defense of plants and animals. These receptors were first discovered in Drosophila melanogaster in the late 20th century which later led to the identification of mammalian homologs. Human TLR family consists of...

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