{"id":10037,"date":"2020-06-26T14:44:40","date_gmt":"2020-06-26T09:14:40","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=10037"},"modified":"2025-05-08T15:41:43","modified_gmt":"2025-05-08T10:11:43","slug":"cytomegalovirus-seroprevalence-market","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/cytomegalovirus-seroprevalence-market","title":{"rendered":"The Increasing Global Burden of Cytomegalovirus Seroprevalence"},"content":{"rendered":"\n<p><strong>Cytomegalovirus (CMV)<\/strong> is a common herpes virus, and approximately 50 to 80 per cent of the adult US population has had a CMV infection by the time they turn 40. Once the virus infects an individual, it stays in their bodies in dormant form.&nbsp;<\/p>\n\n\n\n<p>The estimates by DelveInsight suggest that the <a href=\"https:\/\/www.delveinsight.com\/report-store\/cytomegalovirus-cmv-infection-epidemiology-forecast\" class=\"ek-link\"><strong>total number of diagnosed cytomegalovirus patients<\/strong><\/a> in the 7MM were found out to be 110,580 in 2017. The global burden of Cytomegalovirus Infection is expected to increase further. In the 7MM, the United States has reported having the highest Cytomegalovirus infection cases. In most individuals, primary infection with CMV is asymptomatic, with the infected host showing no signs or symptoms of the disease.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-who-are-all-at-risk-nbsp\"><strong>Who are all at risk?&nbsp;<\/strong><\/h2>\n\n\n\n<p>People who are at greater risk of getting cytomegalovirus infection are pregnant women, fetuses, people with immunocompromised responses, infants, and those who work closely with them. Moreover, people who have had organ\/stem cell transplants, or blood transfusions can also get infected with CMV infection. People who are <a href=\"https:\/\/www.delveinsight.com\/report-store\/hiv-associated-lipodystrophy-market\">HIV<\/a>-infected, or <a href=\"https:\/\/www.delveinsight.com\/report-store\/non-small-cell-lung-cancer-market\"><strong>cancer <\/strong><\/a>patients or who have multiple sex partners also have a higher chance of viremia.&nbsp;<\/p>\n\n\n\n<p>It has been seen that people with healthy immune responses show little to no symptoms; however, an immunocompromised person can experience severe issues in eyes, lungs, liver, stomach, esophagus, and brain. The case is totally different in case of Infants born with congenital cytomegalovirus infection as over 90 per cent of the infants born with cytomegalovirus infection suffer from some serious complications such as hearing loss, visual impairment, mental retardation or epilepsy. The case even worsens if the babies are born prematurely. Moreover, reinfection with the same or different strain can even lead to organ failure if not treated timely. The virus often is associated with serious sequelae in individuals once infected with cytomegalovirus infections, especially in weakened immunity. The CMV infections can often lead to several infections such as <a href=\"https:\/\/www.delveinsight.com\/report-store\/retinitis-pigmentosa-market\"><strong>retinitis<\/strong><\/a>, <a href=\"https:\/\/www.delveinsight.com\/report-store\/pneumonia-pneumococcal-market\"><strong>pneumonia<\/strong><\/a>, gastrointestinal ulcers, encephalitis, and others (mouth ulcers, pharyngitis, and others).&nbsp;&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-cytomegalovirus-infection-market\"><strong>Cytomegalovirus Infection Market<\/strong><\/h2>\n\n\n\n<p>The <a href=\"https:\/\/www.delveinsight.com\/report-store\/cytomegalovirus-cmv-infection-market\" class=\"ek-link\"><strong>cytomegalovirus infection market<\/strong><\/a> in the 7 Major Markets was estimated to be approximately <strong>USD<\/strong> <strong>1195.27 million<\/strong> in 2017. The United States was observed to be occupying the maximum chunk of the Cytomegalovirus infection market in the 7MM. Among EU-5 countries, France was leading maximum CMV infection market share while Italy had the least CMV infection market share.\u00a0<\/p>\n\n\n\n<p>The total therapeutic market is categorized into two groups, i.e. <strong>prophylactics<\/strong> intended to prevent the infection, and <strong>therapeutics<\/strong> to tame down the infection. The cytomegalovirus infection market size of prophylactics in the 7MM was estimated to be approximately USD 771.53 million in 2017.&nbsp;<\/p>\n\n\n\n<p>There are two primary options that exist in the cytomegalovirus infection market for the prevention of the infection after liver transplantation includes <strong>preemptive therapy<\/strong> and <strong>antiviral prophylaxis<\/strong>. For preventive therapy, patients are monitored for evidence of CMV replication by sensitive assays, most commonly using quantitative nucleic acid amplification tests by PCR and less commonly by detection of pp65 antigenemia. Upon detection of asymptomatic CMV replication, antiviral therapy is administered preemptively to prevent progression to symptomatic clinical disease. Although vaccines, to render CMV weak, are still in preclinical stages, there exist some treatment options. One study revealed that hyperimmune globulin, when given to pregnant women with CMV, may help prevent the fetus from contracting the infection. The CMV infection market size of therapeutics was approximately USD 423.74 million.&nbsp;<\/p>\n\n\n\n<p>The cytomegalovirus infection market consists of antiviral drugs following transplant procedures. The drugs include valganciclovir, ganciclovir, cidofovir, foscarnet, or a combination, etc. <strong>Ganciclovir<\/strong> (GCV) is the first antiviral agent that got approved and till now remain the first\u2010line treatment for CMV infection and CMV infection in transplant recipients. The drug has proved to be effective at reducing CMV infections following both HSCT solid organ transplant, and it even improves some of the disabilities seen in these infants.<\/p>\n\n\n\n<p>However, no therapy exists that can cure cytomegalovirus infection. CMV infections can only be controlled by drug therapy. Ganciclovir and foscarnet, are two drugs, which prevent the worsening of the CMV infection. As second\u2010line therapies, <strong>Cidofovir<\/strong> (Vistide, Gilead), is available in the cytomegalovirus infection market. The market also has plenty of generic products of off patented drugs such as <strong>Valcyte<\/strong> that occupy significant market share.&nbsp; This overflow of the market with the generic drugs have negatively impacted the growth of the CMV Infection market.&nbsp;<\/p>\n\n\n\n<p>The dynamics of Cytomegalovirus Infection market is anticipated to change during the forecasted period owing to the expected launch of emerging therapies. There are many pipeline therapies under development for the prevention of Congenital Cytomegalovirus and <a href=\"https:\/\/www.delveinsight.com\/report-store\/cytomegalovirus-cmv-infection-pipeline-insight\"><strong>treatment of Cytomegalovirus infection<\/strong><\/a> following transplant (allogeneic hematopoietic stem cell transplantation\/Solid\u2010organ transplantation). Expected launch of potential therapies may increase market size in the coming years, assisted by an increase in the diagnosed population of Cytomegalovirus Infection. Upcoming therapies for the prophylaxis CMV such as <strong>Cytotect\u201070<\/strong> (BioTest, (EU5 only)), <strong>V160<\/strong> (Merck Sharp &amp; Dohme Corp), <strong>Triplex<\/strong> (Helocyte) and recently launched <strong>Prevymis<\/strong> (Letermovir), have the potential to create a significant positive shift in the Prophylactic CMV market size.&nbsp; Upcoming therapies for the treatment of CMV infection that shall impact the CMV infection market include <strong>Maribavir<\/strong> (Shire), <strong>ATA230<\/strong> (Atara Biotherapeutics), and <strong>Viralym\u2010M<\/strong> (ViraCyte).&nbsp;&nbsp;<\/p>\n\n\n\n<p>The upcoming therapies will surely lend a hand in preventing congenital disease in neonates. Moreover, the oral formulations will have a better adaption rate as compared to intravenous injections. The currently approved systemic drugs have an unfavorable safety profile, with severe acute and long\u2010term toxicities, especially for the pediatric population where long\u2010term reproductive toxicity and carcinogenicity are significant concerns due to the CMV infection. The therapies in the pipeline shall be able to address all the unmet needs driving the cytomegalovirus infection market forward in the coming years.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cytomegalovirus (CMV) is a common herpes virus, and approximately 50 to 80 per cent of the adult US population has had a CMV infection by the time they turn 40. Once the virus infects an individual, it stays in their bodies in dormant form.&nbsp; The estimates by DelveInsight suggest that the total number of diagnosed [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10038,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[17,17434],"tags":[18501,1618,18378,18499,15520,15522,15519,18493,18492,18491,18496,15521,18498,18500,395,4502,18497,18490,852,18495,18494,18503,18502],"industry":[17225],"therapeutic_areas":[17231,17243],"class_list":["post-10037","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","category-facts-and-figures","tag-ata230","tag-atara-biotherapeutics","tag-biotest","tag-cmv-market-size","tag-cytomegalovirus","tag-cytomegalovirus-infection-market","tag-cytomegalovirus-seroprevalence","tag-cytotect70","tag-encephalitis","tag-gastrointestinal-ulcers","tag-helocyte","tag-herpes-virus","tag-letermovir","tag-maribavir","tag-merck","tag-pneumonia","tag-prevymis","tag-retinitis","tag-shire","tag-triplex","tag-v160","tag-viracyte","tag-viralym-m","industry-pharmaceutical","therapeutic_areas-infectious-diseases","therapeutic_areas-respiratory-diseases"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v25.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cytomegalovirus Seroprevalence Market | Cytomegalovirus (CMV) Market<\/title>\n<meta name=\"description\" content=\"The cytomegalovirus infection market in the 7 Major Markets was estimated to be approximately USD 1195.27 million in 2017, which by 2030 is expected to reac\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.delveinsight.com\/blog\/cytomegalovirus-seroprevalence-market\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cytomegalovirus Seroprevalence Market | Cytomegalovirus (CMV) Market\" \/>\n<meta property=\"og:description\" content=\"The cytomegalovirus infection market in the 7 Major Markets was estimated to be 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href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Articles<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Facts and Figures<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Articles<\/span>","<span class=\"advgb-post-tax-term\">Facts and Figures<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">ATA230<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">atara biotherapeutics<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Biotest<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">CMV Market Size<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Cytomegalovirus<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Cytomegalovirus Infection Market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Cytomegalovirus Seroprevalence<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Cytotect?70<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Encephalitis<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Gastrointestinal Ulcers<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Helocyte<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">herpes virus<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Letermovir<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Maribavir<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Merck<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">pneumonia<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Prevymis<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Retinitis<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Shire<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Triplex<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">V160<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Viracyte<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Viralym M<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">ATA230<\/span>","<span class=\"advgb-post-tax-term\">atara biotherapeutics<\/span>","<span class=\"advgb-post-tax-term\">Biotest<\/span>","<span class=\"advgb-post-tax-term\">CMV Market Size<\/span>","<span class=\"advgb-post-tax-term\">Cytomegalovirus<\/span>","<span class=\"advgb-post-tax-term\">Cytomegalovirus Infection Market<\/span>","<span class=\"advgb-post-tax-term\">Cytomegalovirus Seroprevalence<\/span>","<span class=\"advgb-post-tax-term\">Cytotect?70<\/span>","<span class=\"advgb-post-tax-term\">Encephalitis<\/span>","<span class=\"advgb-post-tax-term\">Gastrointestinal Ulcers<\/span>","<span class=\"advgb-post-tax-term\">Helocyte<\/span>","<span class=\"advgb-post-tax-term\">herpes 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