{"id":13420,"date":"2021-09-21T18:15:02","date_gmt":"2021-09-21T12:45:02","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=13420"},"modified":"2023-04-04T11:43:55","modified_gmt":"2023-04-04T06:13:55","slug":"pharma-happenings-for-biogen-smartlabs-synlogic-partner-therapeutics","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/pharma-happenings-for-biogen-smartlabs-synlogic-partner-therapeutics","title":{"rendered":"Biogen\u2019s AMD Biosimilar Gets Approval; SmartLabs Series B Funding; BARDA, Partner Therapeutics in Sepsis Space; Synlogic to Explore Sepsis Market Domain"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_76 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69f7734828f11\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69f7734828f11\"  aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-happenings-for-biogen-smartlabs-synlogic-partner-therapeutics\/#Win-win_for_Biogen_as_its_Biosimilar_Gets_Approval_for_AMD\" >Win-win for Biogen as its Biosimilar Gets Approval for AMD&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-happenings-for-biogen-smartlabs-synlogic-partner-therapeutics\/#SmartLabs_Announces_USD250_Million_Series_B_Financing\" >SmartLabs Announces USD250 Million Series B Financing<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-happenings-for-biogen-smartlabs-synlogic-partner-therapeutics\/#BARDA_and_Partner_Therapeutics_Collaborate_to_Strengthen_Sepsis_Treatment_Space\" >BARDA and Partner Therapeutics Collaborate to Strengthen Sepsis Treatment Space&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-happenings-for-biogen-smartlabs-synlogic-partner-therapeutics\/#Synlogic_Unveils_Results_from_Multiple_Clinical_Studies_on_Phenylketonuria\" >Synlogic Unveils Results from Multiple Clinical Studies on Phenylketonuria<\/a><\/li><\/ul><\/nav><\/div>\n\n<h2 class=\"wp-block-heading\" id=\"h-win-win-for-biogen-as-its-biosimilar-gets-approval-for-amd\"><span class=\"ez-toc-section\" id=\"Win-win_for_Biogen_as_its_Biosimilar_Gets_Approval_for_AMD\"><\/span><strong>Win-win for Biogen as its Biosimilar Gets Approval for AMD&nbsp;<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Samsung Bioepis and Biogen&#8217;s biosimilar drug, <strong>Byooviz<\/strong>, received USFDA approval for the treatment of vision loss, <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/age-related-macular-degeneration-pipeline-insight\" class=\"ek-link\">Age-related macular degeneration<\/a><\/strong> and has become the first biosimilar to Lucentis in the AMD market. The Lucentis copycat had also managed to score regulatory approval in the United Kingdom and Europe last month.<\/p>\n\n\n\n<p><strong>Lucentis<\/strong>, co-developed by Novartis and Roche, was the first VEGF inhibitor to receive recommendation for wet age-related macular degeneration (AMD) more than a decade ago. However, in the past few years, the AMD market was seemingly dominated by Regeneron and Bayer&#8217;s <strong>Eylea <\/strong>owing to less frequent annual injection doses; and now it seems the era of biosimilars in the <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/age-related-macular-degeneration-amd-market\" class=\"ek-link\">AMD market<\/a><\/strong> has begun.<\/p>\n\n\n\n<p>AMD affects over 10 million people in the US alone, and is the leading cause of the irreversible vision loss in the population of age over 60. From a market point of view, it offers vast opportunities to pharma and biotech players to explore and launch their novel therapeutic agents. The arrival of biosimilars, however, brings bad news to the market size growth as the profit quadrant of companies with their novel assets nearing patent expiries starts to diminish. Even so, biosimilars help in improving therapy access to a vast patient pool at affordable prices thus reducing the burden on patients and caretakers.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"SmartLabs_Announces_USD250_Million_Series_B_Financing\"><\/span><strong>SmartLabs Announces USD250 Million Series B Financing<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>SmartLabs, a Boston-based Laboratory-as-a-Service (LaaS) leader, announced the funding of <strong>USD 250 million<\/strong> in a Series B financing round. The company has managed to nab USD 330 million in the past 18 months and plans to expand its integrated lab space offerings that includes multifunctional R&amp;D labs, vivarium, pilot-scale manufacturing, and cGMP.&nbsp;<\/p>\n\n\n\n<p>The funding round was led by ArrowMark Partners along with the new investment partners including Winslow Capital Management and Onex Falcon, joined by existing investors ArrowMark Partners, Conversion Venture Capital (CVC2) and Breed\u2019s Hill Capital.&nbsp;<\/p>\n\n\n\n<p>SmartLabs plans to use the proceeds to augment its overall growth, with a plan to scale operations to 2 million square feet within five years. Further, SmartLabs announced the launch of the fourth version of its proprietary laboratory operations system (<strong>SmartLabs OS<\/strong>) which was first pioneered and introduced in 2016.<\/p>\n\n\n\n<p>The company aims to become a global outsourcing platform that incorporates the scientific and infrastructure resources required by pharma\/ biotech companies to facilitate drug discovery, development, and launch at various stages and sizes.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"BARDA_and_Partner_Therapeutics_Collaborate_to_Strengthen_Sepsis_Treatment_Space\"><\/span><strong>BARDA and Partner Therapeutics Collaborate to Strengthen Sepsis Treatment Space&nbsp;<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Partner Therapeutics announced a collaboration with the Biomedical Advanced Research and Development Authority (BARDA) to accelerate the development of a new diagnostic approach to help identify immunoparalysis <a href=\"https:\/\/www.delveinsight.com\/report-store\/sepsis-epidemiology-forecast\"><strong>sepsis patients<\/strong><\/a>, who can be benefitted from <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/leucine-rich-repeat-kinase-lrrk-2-inhibitor-pipeline-insight\">Leukine <\/a>(sargramostim)<\/strong>.&nbsp;<\/p>\n\n\n\n<p>The advanced technology of a Laboratory Developed Test (LDT) for monocyte HLA-DR, the identification of the immuno-suppressed or immuno-paralyzed sepsis patients is expected to become easier and more convenient. It will further enable the administration of a precision medicine approach to maximize clinical benefit from immune boosting study therapy with Leukine.&nbsp;<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/sepsis-pipeline-insight\">Sepsis<\/a> <\/strong>is a life-threatening organ dysfunction that affected a total of 3,400,940 people in the 7MM in 2020, estimated DelveInsight. The condition does not have many therapy options with only a few approved therapies including Giapreza injection, Onoact and Empressin. <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/sepsis-market\">Sepsis market<\/a><\/strong> also has been witnessing a lot of clinical failures of pipeline assets in late-stage clinical trials.&nbsp;<\/p>\n\n\n\n<p>Thus, the company believes, if successful, its novel diagnostics assay will be able to leverage the potential of immunomodulating therapeutics in the Sepsis therapy domain.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Synlogic_Unveils_Results_from_Multiple_Clinical_Studies_on_Phenylketonuria\"><\/span><strong>Synlogic Unveils Results from Multiple Clinical Studies on Phenylketonuria<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Synlogic, a clinical stage, Massachusetts-based biotech, announced positive results from numerous clinical studies evaluating two engineered microbes\u2014SYNB1618 and SYNB1934\u2014for the treatment of <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/phenylketonuria-pku-market\">Phenylketonuria<\/a><\/strong>.<\/p>\n\n\n\n<p>SYNB1618 managed to display clinically meaningful reductions of phenylalanine (Phe) at several dose levels, across multiple time points, in an interim analysis of the Phase 2 <strong>SynPheny-1<\/strong> study. In a similar line, SYNB1934, an optimized strain evolved from SYNB1618, showed two-fold higher activity than SYNB1618 in a head-to-head Phase 1 study in healthy volunteers, as measured by biomarkers of Phe metabolism.<\/p>\n\n\n\n<p>The company now plans to incorporate SYNB1934 into an arm of the Phase 2 SynPheny-1 trial with final results expected in the first half of 2022, on the basis of which the initiation of a pivotal Phase 3 study for the most promising strain is expected to depend.&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Win-win for Biogen as its Biosimilar Gets Approval for AMD&nbsp; Samsung Bioepis and Biogen&#8217;s biosimilar drug, Byooviz, received USFDA approval for the treatment of vision loss, Age-related macular degeneration and has become the first biosimilar to Lucentis in the AMD market. The Lucentis copycat had also managed to score regulatory approval in the United Kingdom [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":13425,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":3,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[32],"tags":[17065,420,639,18821,18836],"industry":[],"therapeutic_areas":[17240,17231,17244,17234],"class_list":["post-13420","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-notizia","tag-age-related-macular-degeneration-2","tag-news","tag-pharma-news","tag-phenylketonuria","tag-sepsis","therapeutic_areas-endocrinology-and-metabolic-disorders","therapeutic_areas-infectious-diseases","therapeutic_areas-ophthalmology","therapeutic_areas-rare-diseases"],"acf":[],"yoast_head":"<!-- This site is optimized 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href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Notizia - Recent Pharma, Healthcare and Biotech Happenings<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Notizia - Recent Pharma, Healthcare and Biotech Happenings<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Age-Related Macular Degeneration<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">news<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">pharma news<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Phenylketonuria<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Sepsis<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Age-Related Macular Degeneration<\/span>","<span class=\"advgb-post-tax-term\">news<\/span>","<span 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am"},"featured_img_caption":"pharma-biotech-news-updates-for-biogen-smartlabs-synlogic-partner-therapeutics","series_order":"","_links":{"self":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/13420","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/comments?post=13420"}],"version-history":[{"count":0,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/13420\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media\/13425"}],"wp:attachment":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media?parent=13420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/categories?post=13420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/tags?post=13420"},{"taxonomy":"industry","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/industry?post=13420"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/therapeutic_areas?post=13420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}