{"id":164,"date":"2014-12-17T10:12:41","date_gmt":"2014-12-17T10:12:41","guid":{"rendered":"http:\/\/delveinsightblog.wordpress.com\/?p=164"},"modified":"2025-05-02T16:35:49","modified_gmt":"2025-05-02T11:05:49","slug":"break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports","title":{"rendered":"Break the Gene Therapy Barrier with DelveInsight\u2019s Gene Therapy Reports"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_76 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69f14d4ce5956\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69f14d4ce5956\"  aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.delveinsight.com\/blog\/break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports\/#About_Gene_Therapy\" >About Gene Therapy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.delveinsight.com\/blog\/break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports\/#Gene_Therapy_The_Past\" >Gene Therapy: The Past<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.delveinsight.com\/blog\/break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports\/#Gene_Therapy_The_Present_Scenario\" >Gene Therapy: The Present Scenario<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.delveinsight.com\/blog\/break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports\/#Gene_Therapy_The_Market_Scenario\" >Gene Therapy: The Market Scenario<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.delveinsight.com\/blog\/break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports\/#DelveInsights_Gene_Therapy_Reports\" >DelveInsight\u2019s Gene Therapy Reports<\/a><\/li><\/ul><\/nav><\/div>\n<blockquote>\n<p style=\"text-align:center;\"><strong><span style=\"color:#ff6600;\">Gene Therapy: The Future is here!<\/span><\/strong><\/p>\n<\/blockquote>\n<p style=\"text-align:justify;\"><strong>Scientific research and clinical trials aren\u2019t glamorous, but they are essential for effective treatments and perhaps ultimately a cure for various debilitating diseases like cancer etc. Gene therapy&#8217;s potential to revolutionize medicine in the future is exciting, and one day it may be possible to treat an unborn child for a genetic disease even before symptoms appear.<\/strong><\/p>\n<h3><span class=\"ez-toc-section\" id=\"About_Gene_Therapy\"><\/span><span style=\"color:#800000;\">About Gene Therapy<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align:justify;\"><span style=\"color:#333399;\">Gene Therapy involves using genes as medicines by transferring a therapeutic gene through a genetically engineered vector into the targeted cells of a patient to repair an unhealthy gene thus help in curing disease by synthesizing correct proteins. Put simply, it introduces a &#8220;good&#8221; gene into a person who has a disease caused by a &#8220;bad&#8221; gene.<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Gene_Therapy_The_Past\"><\/span><span style=\"color:#800000;\">Gene Therapy: The Past<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align:justify;\"><span style=\"color:#333399;\">Gene therapy has had rather a bad decade as it got off with two unapproved trials in the early 70s and early 80s in which first one was an attempt made to treat two young girls with arginase deficiency syndrome using in vivo gene therapy with wild-type Shope papilloma virus in order to replace the missing arginase enzyme in the patients and the second one was ex vivo gene therapy for \u00df-thalassemia, a bone marrow transplant using marrow cells treated with a \u00df-globin-containing plasmid, again in two patients. Unfortunately in neither case was any real follow-up reported, since both trials were stopped. The final blow to Gene therapy field came in September 1999 with the widely publicized death of an eighteen-year-old man undergoing gene therapy for a liver disease at the University of Pennsylvania, an event that brought the scrutiny of the press onto the world of gene therapy.<\/span><\/p>\n<p style=\"text-align:justify;\"><span style=\"color:#333399;\">But at the turn of the millennium, through the year 2000, reports of the first successful trials began to be heard indicating that real success may be just around the corner: factor IX for hemophilia, transduced stem cells for X-linked SCID, and oncolytic vectors etc. In the ten year cycle of failed clinical trials the researchers learned from their mistakes and developed much more realistic approach and solutions to many of the problems which led to major clinical and commercial successes.<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Gene_Therapy_The_Present_Scenario\"><\/span><span style=\"color:#800000;\">Gene Therapy: The Present Scenario<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align:justify;\"><span style=\"color:#333399;\">The past two decades have seen significant increase in the companies coming up with gene therapies for various therapeutic areas. The human clinical trials are majorly performed for the oncology indications. However, the market for gene therapy is currently in the experimental stages due the risk involved with the use of genes designed in laboratory growth as well as the regulatory approval of products which are currently in clinical trials resulting in only three drugs hitting the market in past decade. Inspite of this, Gene therapy has proved to be a promising approach for many incurable diseases with many promising therapies in phase III clinical trials.<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Gene_Therapy_The_Market_Scenario\"><\/span><span style=\"color:#800000;\">Gene Therapy: The Market Scenario<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align:justify;\"><span style=\"color:#333399;\">Many companies have started investing in and researching on gene therapy due to its promising effects. A growing number of Big Pharma companies are partnering in drug development with innovation-rich biotech firms. Large Pharmaceutical and Biotechnology giants, such as Novartis, GlaxoSmithKline, Sanofi etc., are operating in the gene therapy domain. Moreover recent academic and industry partnerships for example between Celgene Corporation and Baylor College of Medicine, GSK and the Roswell Park Cancer Institute etc., are driving new gene therapy research. The industry\u2019s collective pipeline is brimming with 300+ drugs of which oncology collectively accounts for 29 % of gene therapies in pipeline. Despite of high cost involved recent years have seen many companies coming up for the treatment of deadly diseases. The global market opportunities for gene therapy have risen drastically and continue to be great area of interest for many companies globally.<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"DelveInsights_Gene_Therapy_Reports\"><\/span><span style=\"color:#800000;\">DelveInsight\u2019s Gene Therapy Reports<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align:justify;\"><span style=\"color:#00ff00;\"><strong>DelveInsight\u2019s Gene Therapy Reports<\/strong><\/span> <span style=\"color:#333399;\">cover the entire gene therapy market insights including technology assessments, licensing opportunities, collaborations, market trends, pipeline coverage and competitive landscape. The report essentially provides DelveInsight\u2019s proprietary market and pipeline analytics which identifies the front runners of all therapeutic areas. It also identifies the potential market movers and future regulatory landscape.<\/span><\/p>\n<p style=\"text-align:justify;\"><span style=\"color:#333399;\">The Report insight covers therapy areas like;<\/span> <em><span style=\"color:#ff0000;\">Oncology,<\/span> <span style=\"color:#ff0000;\">Central nervous system, Genetic Disorders, Hematological disorders, Metabolic disorders, Ophthalmology, Cardiovascular disease, Respiratory and Immunology <\/span><\/em><span style=\"color:#333399;\">and many more&#8230;<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gene Therapy: The Future is here! Scientific research and clinical trials aren\u2019t glamorous, but they are essential for effective treatments and perhaps ultimately a cure for various debilitating diseases like cancer etc. Gene therapy&#8217;s potential to revolutionize medicine in the future is exciting, and one day it may be possible to treat an unborn child [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[17],"tags":[143,158,173,180,209,257,259,263,282,356,386,397,427,434,479,514,558,568],"industry":[17225],"therapeutic_areas":[17235],"class_list":["post-164","post","type-post","status-publish","format-standard","hentry","category-articles","tag-cardiovascular-disease","tag-central-nervous-system","tag-collaborations","tag-competitive-landscape","tag-delveinsights-gene-therapy-reports","tag-gene-therapies","tag-gene-therapy-pipeline-assessment","tag-genetic-disorders","tag-hematological-disorders","tag-licensing-opportunities","tag-market-trends","tag-metabolic-disorders","tag-oncology","tag-ophthalmology","tag-pipeline-coverage","tag-respiratory-and-immunology","tag-technology-assessments","tag-therapeutic-gene","industry-pharmaceutical","therapeutic_areas-cell-and-gene-therapy"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v25.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Gene Therapy Market Insights and Future Analysis | DelveInsight<\/title>\n<meta name=\"description\" content=\"Gene Therapy involves using genes as medicines by transferring a therapeutic gene through a genetically engineered vector into the targeted cells...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.delveinsight.com\/blog\/break-the-gene-therapy-barrier-with-delveinsights-gene-therapy-reports\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gene Therapy Market Insights and Future Analysis | DelveInsight\" \/>\n<meta property=\"og:description\" content=\"Gene Therapy involves using genes as medicines by transferring a 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href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Articles<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Articles<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Cardiovascular disease<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Central nervous system<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">collaborations<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Competitive landscape<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">DelveInsight&#039;s Gene Therapy Reports<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Gene Therapies<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Gene Therapy Pipeline Assessment<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Genetic Disorders<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Hematological disorders<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">licensing opportunities<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">market trends<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Metabolic disorders<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Oncology<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Ophthalmology<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Pipeline coverage<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Respiratory and Immunology<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">technology assessments<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Therapeutic gene<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Cardiovascular disease<\/span>","<span class=\"advgb-post-tax-term\">Central nervous system<\/span>","<span class=\"advgb-post-tax-term\">collaborations<\/span>","<span class=\"advgb-post-tax-term\">Competitive landscape<\/span>","<span class=\"advgb-post-tax-term\">DelveInsight&#039;s Gene Therapy Reports<\/span>","<span class=\"advgb-post-tax-term\">Gene Therapies<\/span>","<span class=\"advgb-post-tax-term\">Gene Therapy Pipeline Assessment<\/span>","<span class=\"advgb-post-tax-term\">Genetic Disorders<\/span>","<span class=\"advgb-post-tax-term\">Hematological disorders<\/span>","<span class=\"advgb-post-tax-term\">licensing opportunities<\/span>","<span class=\"advgb-post-tax-term\">market trends<\/span>","<span class=\"advgb-post-tax-term\">Metabolic disorders<\/span>","<span class=\"advgb-post-tax-term\">Oncology<\/span>","<span class=\"advgb-post-tax-term\">Ophthalmology<\/span>","<span class=\"advgb-post-tax-term\">Pipeline coverage<\/span>","<span class=\"advgb-post-tax-term\">Respiratory and Immunology<\/span>","<span class=\"advgb-post-tax-term\">technology assessments<\/span>","<span class=\"advgb-post-tax-term\">Therapeutic gene<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 11 years ago","modified":"Updated 12 months ago"},"absolute_dates":{"created":"Posted on Dec 17, 2014","modified":"Updated on May 2, 2025"},"absolute_dates_time":{"created":"Posted on Dec 17, 2014 10:12 am","modified":"Updated on May 2, 2025 4:35 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