{"id":2065,"date":"2017-04-20T11:34:48","date_gmt":"2017-04-20T11:34:48","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=2065"},"modified":"2021-07-24T12:56:44","modified_gmt":"2021-07-24T07:26:44","slug":"the-business-cocktail-19","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/the-business-cocktail-19","title":{"rendered":"Drug shortage; Fujifilm invests; Cobra Biologics to pump $19M; The world&#8217;s most pricey drugs"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_76 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-6a3a18d52e776\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-6a3a18d52e776\"  aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.delveinsight.com\/blog\/the-business-cocktail-19\/#Prescription_drug_supply_shortages_fuel_price_hikes_new_research_shows\" >Prescription drug supply shortages fuel price hikes, new research shows<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.delveinsight.com\/blog\/the-business-cocktail-19\/#Fujifilm_invests_116M_in_US_as_it_races_competitors_for_biologics_contract_work\" >Fujifilm invests $116M in U.S. as it races competitors for biologics contract work<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.delveinsight.com\/blog\/the-business-cocktail-19\/#Cobra_Biologics_to_pump_19M_into_its_UK_and_Swedish_production_facilities\" >Cobra Biologics to pump $19M into its U.K. and Swedish production facilities<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.delveinsight.com\/blog\/the-business-cocktail-19\/#The_worlds_most_pricey_drugs_from_a_12M_gene_therapy_to_a_450K_lymphoma_med\" >The world&#8217;s most pricey drugs, from a $1.2M gene therapy to a $450K lymphoma med<\/a><\/li><\/ul><\/nav><\/div>\n<h3 style=\"text-align: justify;\"><\/h3>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"Prescription_drug_supply_shortages_fuel_price_hikes_new_research_shows\"><\/span>Prescription drug supply shortages fuel price hikes, new research shows<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">According to research published by the New England Journal of Medicine and reported by the Wall Street Journal, shortages of prescription drug supplies in the U.S. in recent years resulted in price increases for some drugs. In 2014 and 2015, a shortfall of the bladder-cancer drug BCG triggered a sharp increase in prices for mitomycin, a less effective alternative, according to research published online in the medical journal last week. Mitomycin, a generic produced by Accord Healthcare, saw its price for a single vial nearly double to $869.59 in the summer of 2014 following reports of the BCG shortage. The price for a lower dose of mitomycin jumped 146% to $165.60 during the same period. The shortage of BCG continued into 2015 due to manufacturing quality problems with Sanofi and Merck, driving the costs for mitomycin to $1,415 for the high-dose vial and $272.46 for the lower dose, the research indicated.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"Fujifilm_invests_116M_in_US_as_it_races_competitors_for_biologics_contract_work\"><\/span>Fujifilm invests $116M in U.S. as it races competitors for biologics contract work<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">Japan\u2019s Fujifilm is relatively new to the drug manufacturing realm and has yet to crack $1 billion in sales from its small-molecule operations. But it believes it can grow exponentially by concentrating on biologic drug production and is investing close to $130 million in plants in the U.S. and U.K. to make that happen. Fujifilm Diosynth Biotechnologies has now completed a $93 million Texas manufacturing facility it acquired several years ago, the company announced Tuesday. But with contracts for work rolling in, Fujifilm said it will invest another $23 million to expand that operation, as well as spend about $9 million on its facilities in Billingham, U.K. All of this is with the goal of hitting about $1 billion in biologics contract work by 2023 as it races competitors to capture the burgeoning biologics CDMO business.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"Cobra_Biologics_to_pump_19M_into_its_UK_and_Swedish_production_facilities\"><\/span>Cobra Biologics to pump $19M into its U.K. and Swedish production facilities<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">Cobra Biologics will inject $19 million into facilities located in the U.K. and Sweden to help the CDMO meet increased demand from gene and immunotherapy companies. The expansion is expected to take place over a two-year period to support the company\u2019s R&amp;D activities in developing faster and more cost-effective viral vector and DNA plasmid production platforms. The first phase is slotted for its plant in Keele, England, and will expand the facility\u2019s viral vector phase 3 and commercial manufacturing capabilities. Phase two is scheduled for its plants in Matfors and S\u00f6dert\u00e4lje, Sweden, to double the capacity for high-quality DNA plasmid production and characterization, which is used by CAR T-cell therapy companies targeting acute lymphoblastic leukemia and chronic lymphocytic leukemia to support early clinical phase adeno-associated virus and lentivirus production. The last phase will expand Cobra\u2019s clinical and commercial capabilities for GMP DNA production.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"The_worlds_most_pricey_drugs_from_a_12M_gene_therapy_to_a_450K_lymphoma_med\"><\/span>The world&#8217;s most pricey drugs, from a $1.2M gene therapy to a $450K lymphoma med<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">When Biogen announced the price on its new rare disease drug Spinraza\u2014$750,000 the first year and $375,000 after that\u2014critics popped up immediately. Biogen and its partner Ionis saw their shares drop. Since then, despite the complaints, analysts have raised their expectations for the drug, based on conversations with doctors and payers. But the pricing questions linger, if only in the context of the public debate\u2014and political pushback\u2014pharma\u2019s been facing on its price-setting and price hikes for more than a year now. In a recent accounting of the world\u2019s most expensive drugs, compiled by Reinsurance Group of America, the ranking includes some familiar faces farther down the list\u2014Alexion\u2019s Soliris, for instance, in sixth place at $542,640\u2014and some less-familiar brands as well.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prescription drug supply shortages fuel price hikes, new research shows According to research published by the New England Journal of Medicine and reported by the Wall Street Journal, shortages of prescription drug supplies in the U.S. in recent years resulted in price increases for some drugs. In 2014 and 2015, a shortfall of the bladder-cancer [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1033,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[32],"tags":[776,717,634,857,683],"industry":[17225],"therapeutic_areas":[17238,17228],"class_list":["post-2065","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-notizia","tag-business-cocktail","tag-collaboration","tag-drug-development","tag-drug-licensing","tag-mergers-and-acquisitions","industry-pharmaceutical","therapeutic_areas-genetic-disorders","therapeutic_areas-oncology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO 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