{"id":23435,"date":"2023-06-12T17:13:22","date_gmt":"2023-06-12T11:43:22","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=23435"},"modified":"2023-06-12T17:16:20","modified_gmt":"2023-06-12T11:46:20","slug":"chronic-kidney-disease-ckd-treatment","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment","title":{"rendered":"Evolving Therapeutics in Chronic Kidney Disease (CKD) Treatment Market"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_76 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69f461a79f6e6\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69f461a79f6e6\"  aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\/#Chronic_kidney_disease_burden_and_diagnostic_barriers\" >Chronic kidney disease burden and diagnostic barriers<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\/#Chronic_kidney_disease_etiologies\" >Chronic kidney disease etiologies<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\/#Conventional_chronic_kidney_disease_treatment_and_associated_unmet_need\" >Conventional chronic kidney disease treatment and associated unmet need<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\/#Broadening_chronic_kidney_disease_therapeutic_approaches\" >Broadening chronic kidney disease therapeutic approaches<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\/#Emerging_chronic_kidney_disease_pipeline_and_their_mechanisms\" >Emerging chronic kidney disease pipeline and their mechanisms<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\/#Changes_anticipated_in_the_chronic_kidney_disease_treatment_paradigm_and_market\" >Changes anticipated in the chronic kidney disease treatment paradigm and market<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\/#FAQs\" >FAQs<\/a><\/li><\/ul><\/nav><\/div>\n\n<h2 class=\"wp-block-heading\" id=\"h-chronic-kidney-disease-burden-and-diagnostic-barriers\"><span class=\"ez-toc-section\" id=\"Chronic_kidney_disease_burden_and_diagnostic_barriers\"><\/span><strong>Chronic kidney disease burden and diagnostic barriers<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Chronic kidney disease (CKD) is a progressive and irreversible ailment characterized by gradual loss of kidney function. It is clinically defined by a glomerular filtration rate of less than 60mL\/min\/1.73m<sup>2 <\/sup>or albuminuria of at least 30mg per 24 hours, or any occurrence of markers for kidney damage. The disease has a high patient burden.&nbsp;&nbsp;<\/p>\n\n\n\n<p>According to Delveinsight\u2019s \u201c<a href=\"https:\/\/www.delveinsight.com\/report-store\/chronic-kidney-disease-chronic-renal-failure-epidemiology-forecast\">Chronic Kidney Disease Epidemiology Forecast<\/a>\u201d report, almost <strong>76 million<\/strong> people are affected in the 7MM countries. Further, it has been estimated that less than a quarter of these patients are actually diagnosed with the condition suggesting an abysmally low awareness of the disease. The disease is detected only when it progresses to more severe stages, with more than two-thirds of the cases being diagnosed in Stage 3 and above. These diagnostic delays augment the already overwhelmed healthcare system.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Chronic_kidney_disease_etiologies\"><\/span><strong>Chronic kidney disease etiologies<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>CKD may be a result of a combination of different complications. It occurs when a disease impairs kidney function, causing kidney damage over time. The most prominent cause of CKD is diabetes, followed by hypertension. Polycystic kidney disease \u2013a genetic disease\u2014may also result in the loss of renal function. Other causes may include glomerular diseases (such as glomerulonephritis, IgA nephropathy), or infection. As multiple chronic kidney disease drugs are prescribed to treat comorbidities, and almost half of these are eliminated via&nbsp;the kidney, the chances of drug toxicity increase making it an additional cause for concern.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><a href=\"https:\/\/www.delveinsight.com\/infographics\/chronic-kidney-disease-chronic-renal-failure-market\"><img decoding=\"async\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics-1024x194.png\" alt=\"Chronic Kidney Disease Infographics\" class=\"wp-image-23441\" width=\"768\" height=\"146\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics-1024x194.png 1024w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics-300x57.png 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics-150x28.png 150w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics-768x145.png 768w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics-1536x291.png 1536w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics-1568x297.png 1568w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165319\/Chronic-Kidney-Disease-Infographics.png 1584w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conventional_chronic_kidney_disease_treatment_and_associated_unmet_need\"><\/span><strong>Conventional chronic kidney disease treatment and associated unmet need<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Renin angiotensive system inhibitors (RAS inhibitors) which include Angiotensive receptor blockers (ARBs) and Angiotensin-converting enzyme inhibitors (ACE inhibitors) have been the cornerstones of chronic kidney disease treatment for around two decades, due to their renal protecting mechanisms. <a href=\"https:\/\/www.delveinsight.com\/report-store\/diabetic-kidney-disease-dkd-market\">Diabetes-associated kidney disease patients (DKD)<\/a>, which is the major pool for CKD, are also given antidiabetic drugs focusing on glycemic control such as metformin, sodium-glucose cotransporter 2 inhibitor (SGLT2 inhibitor), and Glucagon-like peptide 1 (GLP1 drugs) along with the traditional antihypertensive drugs. In the case of hypertension-induced CKD patients it is crucial to manage high blood pressure and drugs such as ACE inhibitors\/ARBs, calcium channel blockers, and diuretics are usually prescribed. Despite <a href=\"https:\/\/www.delveinsight.com\/report-store\/chronic-kidney-disease-competitive-landscape\">available chronic kidney disease treatments<\/a>, however, there is continued progression of the disease along with the chances of therapy-induced rapid renal deterioration and hyperkalemia.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Broadening_chronic_kidney_disease_therapeutic_approaches\"><\/span><strong>Broadening chronic kidney disease therapeutic approaches<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Mineralocorticoid receptor antagonists (MRAs) is a class of drugs used to retard CKD progression. Pathophysiological over-activation of the mineralocorticoid receptors expressed in the kidneys can lead to inflammation and fibrosis. Spironolactone, a steroidal MRA, has been known to reduce albuminuria in people with diabetes and elevated urinary albumin; however, there are concerns regarding the risk for hyperkalemia and acute kidney injury (AKI). In contrast, non-steroidal MRA such as <strong>Finerenone<\/strong>, approved under the brand name <strong>KERENDIA (Bayer)<\/strong> has shown to have more potent anti-inflammatory and antifibrotic effects than steroidal MRAs while also cutting the risk of sudden cardiac death in these patients.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165430\/Chronic-Kidney-Disease-Key-Insights.png\" alt=\"Chronic Kidney Disease Key Insights\" class=\"wp-image-23442\" width=\"450\" height=\"228\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165430\/Chronic-Kidney-Disease-Key-Insights.png 900w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165430\/Chronic-Kidney-Disease-Key-Insights-300x152.png 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165430\/Chronic-Kidney-Disease-Key-Insights-150x76.png 150w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165430\/Chronic-Kidney-Disease-Key-Insights-768x389.png 768w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/figure>\n\n\n\n<p>SGLT2 inhibitors are another important class of drugs used to lower blood sugar levels in adults with type 2 diabetes while preventing the kidneys from reabsorbing sugar that is created by the body. <strong>Johnson &amp; Johnson\u2019s Invokana (Canagliflozin)<\/strong>, one such SGLT2 inhibitor, is used to slow the progression of kidney damage in patients with diabetic kidney disease (DKD). <strong>AstraZeneca\u2019s Farxiga (Dapagliflozin)<\/strong> boasts approval for both diabetic and non-diabetic patients with CKD, which has opened a massive chronic kidney disease market opportunity for it. As per Delveinsight\u2019s estimates on the latest published \u201c<a href=\"https:\/\/www.delveinsight.com\/report-store\/chronic-kidney-disease-chronic-renal-failure-market\">Chronic Kidney Disease Market Report<\/a>, in the United States, Farxiga achieved sales of <strong>USD 111 million <\/strong>in its launch year and is estimated to see considerable growth, reaching peak sales of <strong>USD 560 million<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Emerging_chronic_kidney_disease_pipeline_and_their_mechanisms\"><\/span><strong>Emerging chronic kidney disease pipeline and their mechanisms<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>There has been impressive interest in the chronic kidney disease treatment market over the years with several pharma players such as <strong>Prokidney, KBP Biosciences, Boehringer Ingelheim Pharmaceuticals\/Lilly, Reata Pharmaceuticals, Inc., and Novo Nordisk<\/strong> vying for a share of the pie. Prokidney is developing a renal autologous cell therapy (REACT) for DKD patients, to restore kidney function using the patient\u2019s cells. <strong>Novo Nordisk\u2019s Semaglutide<\/strong>, GLP-1 receptor agonist being investigated in Phase III is also targeting DKD patients. For the overall <a href=\"https:\/\/www.delveinsight.com\/report-store\/chronic-kidney-disease-chronic-renal-failure-market\">chronic kidney disease pool<\/a>, there are drugs in mid\/late stages of development such as <strong>Boehringer Ingelheim\u2019s Jardiance (Empagliflozin), Reata Pharmaceuticals\u2019 Bardoxolone methyl, and Novo Nordisk\u2019s Ziltivekimab.<\/strong> Jardiance is currently approved to lower blood sugar and reduce the risk of cardiovascular death in adults with type 2 diabetes. In 2022, Eli Lilly and Boehringer Ingelheim submitted a supplementary New Drug Application for the drug as a prospective treatment for mitigating the risk of end-stage kidney disease. This was based on the results of the <strong>EMPA-KIDNEY <\/strong><strong>Phase III trial,<\/strong> the largest and broadest dedicated SGLT2 inhibitor trial in chronic kidney disease treatment to date. In 2023, FDA accepted the application causing the drug to advance toward its approval for overall chronic kidney disease and compete with rival FARXIGA. Bardoxolone methyl, an NF-kappa B inhibitor, is in phase III trial. In Japan, the drug is being investigated for diabetic patients by <strong>Kyowa Kirin Co., Ltd,<\/strong> in collaboration with the drug originator, Reata Pharmaceuticals. Ziltivekimab is a monoclonal antibody, currently in Phase III trial, and has shown good efficacy in its previous <a href=\"https:\/\/www.delveinsight.com\/report-store\/chronic-kidney-disease-ckd-pipeline-insight\">chronic kidney disease clinical trials<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165241\/Emerging-Therapies-for-Chronic-Kidney-Disease.png\" alt=\"Emerging Therapies for Chronic Kidney Disease\" class=\"wp-image-23440\" width=\"667\" height=\"224\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165241\/Emerging-Therapies-for-Chronic-Kidney-Disease.png 889w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165241\/Emerging-Therapies-for-Chronic-Kidney-Disease-300x101.png 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165241\/Emerging-Therapies-for-Chronic-Kidney-Disease-150x50.png 150w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165241\/Emerging-Therapies-for-Chronic-Kidney-Disease-768x257.png 768w\" sizes=\"(max-width: 667px) 100vw, 667px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Changes_anticipated_in_the_chronic_kidney_disease_treatment_paradigm_and_market\"><\/span><strong>Changes anticipated in the chronic kidney disease treatment paradigm and market<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Jardiance, an already celebrated drug for diabetes and heart failure patients, awaits approval for CKD in 2023, marking another important milestone for <strong>Eli Lilly and Boehringer Ingelheim<\/strong>. As per Delveinsight, the <a href=\"https:\/\/www.delveinsight.com\/report-store\/chronic-kidney-disease-chronic-renal-failure-market\">chronic kidney disease drug<\/a> is expected to gain a sizeable market share, attaining an estimated peak sales of <strong>USD 700-800 million<\/strong> in the US. Bardoxolone methyl and Ziltivekimab are expected to hit the US chronic kidney disease treatment market in 2026 and 2027 with estimated launch sales of <strong>USD 3 million and USD 9 million<\/strong>, respectively. In the DKD market, the <strong>REACT therapy<\/strong> being a novel mechanism is expected to spark considerable interest and its value market share will be driven by its significant cost on account of being a cell therapy.&nbsp;<\/p>\n\n\n\n<p>CKD is a complex disease and treatment will be based on the patient\u2019s needs. As emerging chronic kidney disease drugs are targeting different mechanisms of action, judicious use of therapies with the right dosage recommendations is essential to safeguard renal function decline and manage the disease.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"FAQs\"><\/span><strong>FAQs<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-question-1686222929895\"><strong class=\"schema-faq-question\"><strong>1. What is chronic kidney disease?<\/strong><\/strong> <p class=\"schema-faq-answer\">Chronic kidney disease occurs when the kidneys get damaged and cannot filter blood as efficiently as they should. Chronic kidney disease is defined as abnormalities in kidney structure or function that have been present for more than three months and have a negative impact on health. Chronic kidney disease is categorized into five phases based on the extent of kidney damage and function. In stage 1, there is modest kidney disease, and in stage 5, the kidneys have stopped working. The severity of chronic kidney disease varies.\u00a0<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1686222951963\"><strong class=\"schema-faq-question\"><strong>2. What are chronic kidney disease symptoms?<\/strong><\/strong> <p class=\"schema-faq-answer\">In the early stages of kidney disease, there are usually no chronic kidney disease symptoms. It can only be diagnosed if a blood or urine test is performed for another reason and the results show a kidney issue. Tiredness, swollen ankles, feet, or hands, shortness of breath, unwellness, and blood in the urine indicate a more advanced stage.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1686222980978\"><strong class=\"schema-faq-question\"><strong>3.<\/strong> <strong>How is chronic kidney disease diagnosed?<\/strong><\/strong> <p class=\"schema-faq-answer\">Chronic kidney disease can be detected using blood and urine tests. The eGFR blood test measures the efficiency with which the kidneys function. Ultrasound, CT scan, X-ray, and MRI imaging examinations are also used for chronic kidney disease diagnosis.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1686222992650\"><strong class=\"schema-faq-question\"><strong>4. How is chronic kidney disease treated?<\/strong><\/strong> <p class=\"schema-faq-answer\">There is no cure for CKD, however, treatment can help ease symptoms and keep it from worsening. The treatment approach involves dietary and lifestyle adjustments, as well as medications to decrease blood pressure, blood sugar, or cholesterol. Diuretics are medications that help the kidneys excrete water and reduce edoema. In some circumstances, dialysis may be required. When the kidneys have failed, as in severe CKD, a kidney transplant may be an option.<\/p> <\/div> <\/div>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><a href=\"https:\/\/www.delveinsight.com\/report-store\/chronic-kidney-disease-chronic-renal-failure-market\"><img decoding=\"async\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook-1024x256.png\" alt=\"Chronic Kidney Disease Market Outlook\" class=\"wp-image-23439\" width=\"768\" height=\"192\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook-1024x256.png 1024w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook-300x75.png 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook-150x38.png 150w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook-768x192.png 768w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook-1536x384.png 1536w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook-1568x392.png 1568w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08165201\/Chronic-Kidney-Disease-Market-Outlook.png 1584w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/><\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Chronic kidney disease burden and diagnostic barriers Chronic kidney disease (CKD) is a progressive and irreversible ailment characterized by gradual loss of kidney function. It is clinically defined by a glomerular filtration rate of less than 60mL\/min\/1.73m2 or albuminuria of at least 30mg per 24 hours, or any occurrence of markers for kidney damage. The [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":23436,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":6,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[17],"tags":[3702,2815,7396,7394,7395,7393],"industry":[17225],"therapeutic_areas":[17230],"class_list":["post-23435","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","tag-chronic-kidney-disease","tag-chronic-kidney-disease-ckd","tag-chronic-kidney-disease-market","tag-chronic-kidney-disease-pipeline-insight","tag-chronic-kidney-disease-therapy-market","tag-chronic-kidney-diseases","industry-pharmaceutical","therapeutic_areas-genito-urinary-system-and-sex-hormones"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v25.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Navigating Evolving Chronic Kidney Disease Treatment Market<\/title>\n<meta name=\"description\" content=\"The chronic kidney disease treatment market has emerged immensely over the years with several companies working in the domain such as Novo,\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Navigating Evolving Chronic Kidney Disease Treatment Market\" \/>\n<meta property=\"og:description\" content=\"The chronic kidney disease treatment market has emerged immensely over the years with several companies working in the domain such as Novo,\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment\" \/>\n<meta property=\"og:site_name\" content=\"DelveInsight Business Research\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/DelveInsight-1423323754607782\/\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-12T11:43:22+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-12T11:46:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08164916\/chronic-kidney-disease-ckd-treatment.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Sandeep Joshi\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta 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What is chronic kidney disease?","answerCount":1,"acceptedAnswer":{"@type":"Answer","text":"Chronic kidney disease occurs when the kidneys get damaged and cannot filter blood as efficiently as they should. Chronic kidney disease is defined as abnormalities in kidney structure or function that have been present for more than three months and have a negative impact on health. Chronic kidney disease is categorized into five phases based on the extent of kidney damage and function. In stage 1, there is modest kidney disease, and in stage 5, the kidneys have stopped working. The severity of chronic kidney disease varies.\u00a0","inLanguage":"en-US"},"inLanguage":"en-US"},{"@type":"Question","@id":"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment#faq-question-1686222951963","position":2,"url":"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment#faq-question-1686222951963","name":"2. What are chronic kidney disease symptoms?","answerCount":1,"acceptedAnswer":{"@type":"Answer","text":"In the early stages of kidney disease, there are usually no chronic kidney disease symptoms. It can only be diagnosed if a blood or urine test is performed for another reason and the results show a kidney issue. Tiredness, swollen ankles, feet, or hands, shortness of breath, unwellness, and blood in the urine indicate a more advanced stage.","inLanguage":"en-US"},"inLanguage":"en-US"},{"@type":"Question","@id":"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment#faq-question-1686222980978","position":3,"url":"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment#faq-question-1686222980978","name":"3. How is chronic kidney disease diagnosed?","answerCount":1,"acceptedAnswer":{"@type":"Answer","text":"Chronic kidney disease can be detected using blood and urine tests. The eGFR blood test measures the efficiency with which the kidneys function. Ultrasound, CT scan, X-ray, and MRI imaging examinations are also used for chronic kidney disease diagnosis.","inLanguage":"en-US"},"inLanguage":"en-US"},{"@type":"Question","@id":"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment#faq-question-1686222992650","position":4,"url":"https:\/\/www.delveinsight.com\/blog\/chronic-kidney-disease-ckd-treatment#faq-question-1686222992650","name":"4. How is chronic kidney disease treated?","answerCount":1,"acceptedAnswer":{"@type":"Answer","text":"There is no cure for CKD, however, treatment can help ease symptoms and keep it from worsening. The treatment approach involves dietary and lifestyle adjustments, as well as medications to decrease blood pressure, blood sugar, or cholesterol. Diuretics are medications that help the kidneys excrete water and reduce edoema. In some circumstances, dialysis may be required. When the kidneys have failed, as in severe CKD, a kidney transplant may be an option.","inLanguage":"en-US"},"inLanguage":"en-US"}]}},"author_meta":{"display_name":"Sandeep Joshi","author_link":"https:\/\/www.delveinsight.com\/blog\/author\/sjoshidelveinsight-com"},"featured_img":"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2023\/06\/08164916\/chronic-kidney-disease-ckd-treatment-300x200.png","coauthors":[],"tax_additional":{"categories":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Articles<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Articles<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Chronic Kidney Disease<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Chronic kidney disease (CKD)<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">chronic kidney disease market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">chronic kidney disease pipeline insight<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">chronic kidney disease therapy market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Chronic Kidney diseases<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Chronic Kidney Disease<\/span>","<span class=\"advgb-post-tax-term\">Chronic kidney disease (CKD)<\/span>","<span class=\"advgb-post-tax-term\">chronic kidney disease market<\/span>","<span class=\"advgb-post-tax-term\">chronic kidney disease pipeline insight<\/span>","<span class=\"advgb-post-tax-term\">chronic kidney disease therapy market<\/span>","<span class=\"advgb-post-tax-term\">Chronic Kidney diseases<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 3 years ago","modified":"Updated 3 years ago"},"absolute_dates":{"created":"Posted on Jun 12, 2023","modified":"Updated on Jun 12, 2023"},"absolute_dates_time":{"created":"Posted on Jun 12, 2023 5:13 pm","modified":"Updated on Jun 12, 2023 5:16 pm"},"featured_img_caption":"chronic-kidney-disease-ckd-treatment","series_order":"","_links":{"self":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/23435","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/comments?post=23435"}],"version-history":[{"count":0,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/23435\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media\/23436"}],"wp:attachment":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media?parent=23435"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/categories?post=23435"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/tags?post=23435"},{"taxonomy":"industry","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/industry?post=23435"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/therapeutic_areas?post=23435"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}