{"id":27477,"date":"2024-04-05T12:12:50","date_gmt":"2024-04-05T06:42:50","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=27477"},"modified":"2024-04-05T12:12:52","modified_gmt":"2024-04-05T06:42:52","slug":"fanapt-for-bipolar-disorder-treatment","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/fanapt-for-bipolar-disorder-treatment","title":{"rendered":"Vanda Broadens its Reach to Bipolar Disorder Treatment Market With Fanapt Approval"},"content":{"rendered":"\n<p>Fifteen years after its first FDA approval for treating schizophrenia with <strong>Fanapt (iloperidone)<\/strong>, <strong>Vanda Pharmaceuticals<\/strong> has achieved another success. Fanapt is a type of <strong>antipsychotic medication<\/strong> that deviates from the usual and has been administered to <a href=\"https:\/\/www.delveinsight.com\/report-store\/schizophrenia-market\">individuals with schizophrenia<\/a> for their immediate treatment following its approval by the FDA in 2009. Despite its label stating that the precise method of operation remains unidentified, Vanda suggests that Fanapt functions by inhibiting <strong>dopamine type 2 and serotonin type 2 receptors<\/strong>. The FDA has approved Fanapt tablets for the treatment of manic or mixed episodes linked to bipolar I disorder in adults. This led to a <strong>33%<\/strong> surge in Vanda\u2019s shares during post-market trading.<\/p>\n\n\n\n<p>Affecting approximately<strong> 2.8%<\/strong> of adults in the United States, bipolar disorder is a significant mental health condition distinguished by episodes of low mood interspersed with episodes of elevated mood. In addition, the total bipolar I disorder <a href=\"https:\/\/www.delveinsight.com\/report-store\/bipolar-disorder-manic-depression-market\">cases of bipolar depression<\/a> in the US were observed as <strong>~935K<\/strong> in the year 2021, these cases are estimated to increase in upcoming years. According to our analysis, <strong>~75%<\/strong> of bipolar depression cases were classified as severe in the US in 2021.&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.delveinsight.com\/infographics\/bipolar-disorder-manic-depression-market\"><img decoding=\"async\" width=\"1024\" height=\"194\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic-1024x194.webp\" alt=\"Bipolar Depression Infographic\" class=\"wp-image-27482\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic-1024x194.webp 1024w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic-300x57.webp 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic-150x28.webp 150w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic-768x145.webp 768w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic-1536x291.webp 1536w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic-1568x297.webp 1568w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121008\/Bipolar-Depression-Infographic.webp 1584w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><em>\u201cManic or mixed episodes linked with bipolar I disorder are intricate conditions that demand a range of reliable choices to address the unique needs of each patient. With more than 100,000 patient years of usage, Fanapt is a recognized treatment option that allows for adaptable dosing while maintaining a well-established safety record. This approval from the FDA provides patients and healthcare providers with a fresh approach to handling bipolar I disorder,\u201d stated <\/em><strong><em>Mihael H. Polymeropoulos M.D., who serves as Vanda&#8217;s President, CEO, and Chairman of the Board.<\/em><\/strong><\/p>\n<\/blockquote>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><strong><em>Dr. Polymeropoulos<\/em><\/strong><em> added, \u201cThe announcement made today represents a notable progression for one of Vanda&#8217;s key franchises, highlighting the success of our approach in developing groundbreaking treatments for important medical challenges, ultimately enhancing the well-being of patients. Building upon this achievement, we have built a robust business with a variety of upcoming products, a track record of increasing revenue, and solid financial standing. Our primary commitment remains delivering essential medications to patients globally, all the while fostering enduring, sustainable value.\u201d<\/em><\/p>\n<\/blockquote>\n\n\n\n<p>The FDA\u2019s approval is supported by information gathered from a <strong>Phase III clinical study<\/strong> involving approximately 400 <a href=\"https:\/\/www.delveinsight.com\/report-store\/bipolar-disorder-manic-depression-market\">individuals diagnosed with bipolar I disorder<\/a>. These participants were in the midst of experiencing a manic episode at the time of the trial. Following a four-week treatment period, patients who received Fanapt exhibited notably more substantial enhancements according to the <strong>Young Mania Rating Scale<\/strong>, a measure used to evaluate the intensity of mania, when compared to those who received a placebo. Furthermore, the study revealed that Fanapt has the potential to provide swift benefits for bipolar I disorder, as its significant superiority over the placebo became evident as early as two weeks into the treatment.<\/p>\n\n\n\n<p>Fanapt includes a <strong>boxed warning<\/strong> indicating a higher potential for mortality in elderly patients with dementia-related psychosis when using antipsychotic medications. Vanda is also exploring the use of Fanapt as a remedy for post-traumatic stress disorder (PTSD).<\/p>\n\n\n\n<p>Iloperidone has an extensive background dating back to the mid-1990s when it was under development by <strong>Novartis and Titan Pharmaceuticals<\/strong> until Vanda acquired it in 2004. Despite initially rejecting iloperidone in 2008 due to insufficient clinical data, the FDA approved it in 2009.&nbsp;<\/p>\n\n\n\n<p>When it was introduced, several analysts predicted that sales could hit <strong>$300 million<\/strong> by 2013. However, the drug fell short of these projections. Throughout the following ten years, sales grew gradually, reaching a high point of <strong>$95 million<\/strong> in 2021. Last year, Fanapt brought in <strong>$90 million<\/strong> in revenue.<\/p>\n\n\n\n<p>This successful regulatory outcome will assist Vanda in recovering following the FDA\u2019s recent denial of its <a href=\"https:\/\/www.delveinsight.com\/report-store\/insomnia-market\">insomnia treatment<\/a>, <strong>Hetlioz (tasimelteon)<\/strong>, which targets <strong>melatonin receptors<\/strong>. The rejection follows a prior communication from the regulatory body, indicating issues that currently prevent the discussion of labeling and post-marketing obligations.<\/p>\n\n\n\n<p>Vanda\u2019s decrease in revenue during the past couple of years is mainly because of the dropping sales of its other key product, Hetlioz (tasimelteon). The rise of generic alternatives in the US has led to a significant decline in Hetlioz sales, plummeting from <strong>$160 million<\/strong> in 2022 to <strong>$100 million<\/strong> in the previous year. Additionally, Vanda has faced repeated setbacks in its attempts to secure approvals for Hetlioz\u2019s use in treating insomnia and jet lag disorder.<\/p>\n\n\n\n<p>The company aims to offset the loss in revenue by investing <strong>$100 million<\/strong> to acquire rights for <strong>Johnson &amp; Johnson\u2019s Ponvory<\/strong>, a <a href=\"https:\/\/www.delveinsight.com\/report-store\/multiple-sclerosis-market\">treatment for multiple sclerosis<\/a>, in the US and Canada. Vanda finalized this agreement in December of the previous year.<\/p>\n\n\n\n<p>However, Vanda will get fierce competition from other companies working with their lead assets to improve the bipolar disorder treatment space. One such company working with its asset in the late stage of development is <strong>Lyndra Therapeutics (LYN-005)<\/strong>.&nbsp;<\/p>\n\n\n\n<p>LYN-005, an oral weekly risperidone, is in development for individuals with schizophrenia and bipolar I disorder. Utilizing Lyndra\u2019s innovative <strong>LYNX drug delivery system<\/strong>, this medication offers a once-a-week dosage option compared to the daily regimen of risperidone.&nbsp;<\/p>\n\n\n\n<p>The LYNX platform, stemming from innovations in the Langer Lab, has swiftly advanced since 2015, traversing preclinical and initial human trials. It has validated the platform\u2019s concept and primary asset through a Phase II study recently completed. With its versatility spanning various therapeutic domains, including both existing and emerging drugs, the LYNX drug delivery system holds promise for enhancing treatment adherence and health outcomes. Additionally, it offers the prospect of liberating individuals from the constraints of daily pill regimens, thereby streamlining their lives.<\/p>\n\n\n\n<p>Phase II findings for oral weekly risperidone showed rapid attainment of therapeutic levels, sustained drug levels for weekly dosing, and decreased peak drug exposure. This oral weekly formulation has the potential to become the initial long-lasting oral treatment for individuals managing schizophrenia and bipolar I disorder.<\/p>\n\n\n\n<p>In April 2023, Lyndra Inc. began a study with multiple doses, open-label, parallel-group design to assess the pharmacokinetics, safety, and tolerability of their long-acting oral Risperidone (LYN-005) in individuals diagnosed with Schizophrenia or Schizoaffective Disorder.<\/p>\n\n\n\n<p>The pivotal study included participants with schizophrenia and schizoaffective disorder who were on a stable dose of an oral antipsychotic medication at the start of the study. The study assessed oral weekly risperidone 15 mg and 45 mg, equivalent to 2 mg and 6 mg daily Risperdal, respectively. A total of 90 participants were planned for the study, with a planned interim analysis after 46 participants.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"375\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-1024x375.png\" alt=\"Fanapt\u2019s Development Timeline\" class=\"wp-image-27483\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-1024x375.png 1024w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-300x110.png 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-150x55.png 150w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-768x281.png 768w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-1536x563.png 1536w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-2048x750.png 2048w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05121043\/Fanapts-Development-Timeline-1568x574.png 1568w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>In the interim analysis, the study met the pre-specified primary endpoint, which includes the geometric mean ratio of the Week 5 oral weekly risperidone drug levels compared to the baseline immediate-release Risperdal drug levels. Oral weekly risperidone met the endpoint of a one-sided Cmin of &gt;0.80; a one-sided Cmax of &lt;1.25; and a two-sided Cavg of 0.80-1.40, with 90% confidence limits. With these positive results, the study was stopped early according to the pre-defined stopping criteria.<\/p>\n\n\n\n<p>The study also met its secondary endpoints for safety and the Positive and Negative Syndrome Scale (PANSS) score, a score used for measuring symptom severity in schizophrenia. One key potential benefit of the LYNX drug delivery platform is the ability to deliver more consistent levels of medication compared to daily dosing by reducing the peak-to-trough variation. Oral weekly risperidone (LYN-005) was generally safe and well tolerated.<\/p>\n\n\n\n<p>The approval of LYN-005 will be a great threat to Vanda\u2019s Fanapt. As of now, Vanda Pharmaceuticals\u2019 Fanapt has long been a cornerstone in the <a href=\"https:\/\/www.delveinsight.com\/report-store\/schizophrenia-market\">treatment of schizophrenia<\/a>. Its effectiveness and the trust it has garnered among physicians and patients alike have contributed significantly to Vanda\u2019s position in the pharmaceutical market. However, the landscape might shift with the potential approval of Lyndra\u2019s LYN-005 for the treatment of bipolar disorder, posing challenges and raising questions about Fanapt\u2019s future sales trajectory.<\/p>\n\n\n\n<p>One key aspect that might impact Fanapt\u2019s sales is the efficacy and safety profile of LYN-005. If the new drug demonstrates superior efficacy, fewer side effects, or a more convenient dosing regimen, physicians and patients could be swayed to switch from Fanapt to the new option. This scenario could lead to a gradual decline in Fanapt\u2019s market share, especially if LYN-005 gains momentum post-approval.<\/p>\n\n\n\n<p>Vanda will need to navigate this evolving landscape strategically, focusing on differentiation, innovation, and effective communication to maintain Fanapt\u2019s position in the <a href=\"https:\/\/www.delveinsight.com\/report-store\/bipolar-disorder-manic-depression-market\">bipolar disorder market<\/a> amidst emerging competition.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.delveinsight.com\/report-store\/bipolar-disorder-manic-depression-market\"><img decoding=\"async\" width=\"1024\" height=\"256\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook--1024x256.png\" alt=\"Bipolar Depression Market Outlook \" class=\"wp-image-27481\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook--1024x256.png 1024w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook--300x75.png 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook--150x38.png 150w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook--768x192.png 768w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook--1536x384.png 1536w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook--1568x392.png 1568w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120924\/Bipolar-Depression-Market-Outlook-.png 1584w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Fifteen years after its first FDA approval for treating schizophrenia with Fanapt (iloperidone), Vanda Pharmaceuticals has achieved another success. Fanapt is a type of antipsychotic medication that deviates from the usual and has been administered to individuals with schizophrenia for their immediate treatment following its approval by the FDA in 2009. Despite its label stating [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":27478,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[17],"tags":[22033,16811,7335,7336,7337,22034,22031,22032,21133,3333,1519,16710,18667],"industry":[17225],"therapeutic_areas":[17245],"class_list":["post-27477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","tag-bipolar-depression","tag-bipolar-depression-market","tag-bipolar-disorder","tag-bipolar-disorder-market","tag-bipolar-disorder-treatment-market","tag-bipolar-i-disorder","tag-fanapt","tag-iloperidone","tag-insomnia-treatment","tag-multiple-sclerosis-teatment","tag-schizophrenia","tag-schizophrenia-treatment","tag-vanda-pharmaceuticals","industry-pharmaceutical","therapeutic_areas-neurology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v25.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Vanda&#039;s Fanapt Approval for Bipolar Disorder Treatment<\/title>\n<meta name=\"description\" content=\"The FDA has approved Vanda\u2019s Fanapt tablets for the treatment of manic or mixed episodes linked to bipolar I disorder in adults.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.delveinsight.com\/blog\/fanapt-for-bipolar-disorder-treatment\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vanda&#039;s Fanapt Approval for Bipolar Disorder Treatment\" \/>\n<meta property=\"og:description\" content=\"The FDA has approved Vanda\u2019s Fanapt tablets for the treatment of manic or mixed episodes linked to bipolar I disorder in adults.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.delveinsight.com\/blog\/fanapt-for-bipolar-disorder-treatment\" \/>\n<meta property=\"og:site_name\" content=\"DelveInsight Business Research\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/DelveInsight-1423323754607782\/\" \/>\n<meta property=\"article:published_time\" content=\"2024-04-05T06:42:50+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-05T06:42:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2024\/04\/05120759\/fanapt-for-bipolar-disorder-treatment.png\" \/>\n\t<meta property=\"og:image:width\" content=\"466\" \/>\n\t<meta property=\"og:image:height\" content=\"284\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Sandeep Joshi\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" 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href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Bipolar disorder treatment market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">bipolar I disorder<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Fanapt<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">iloperidone<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Insomnia Treatment<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Multiple Sclerosis Teatment<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">schizophrenia<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Schizophrenia treatment<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Vanda Pharmaceuticals<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">bipolar depression<\/span>","<span class=\"advgb-post-tax-term\">Bipolar depression market<\/span>","<span class=\"advgb-post-tax-term\">Bipolar disorder<\/span>","<span class=\"advgb-post-tax-term\">Bipolar disorder market<\/span>","<span class=\"advgb-post-tax-term\">Bipolar disorder treatment market<\/span>","<span class=\"advgb-post-tax-term\">bipolar I disorder<\/span>","<span class=\"advgb-post-tax-term\">Fanapt<\/span>","<span class=\"advgb-post-tax-term\">iloperidone<\/span>","<span class=\"advgb-post-tax-term\">Insomnia Treatment<\/span>","<span class=\"advgb-post-tax-term\">Multiple Sclerosis Teatment<\/span>","<span class=\"advgb-post-tax-term\">schizophrenia<\/span>","<span class=\"advgb-post-tax-term\">Schizophrenia treatment<\/span>","<span class=\"advgb-post-tax-term\">Vanda Pharmaceuticals<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 2 years ago","modified":"Updated 2 years ago"},"absolute_dates":{"created":"Posted on Apr 5, 2024","modified":"Updated on Apr 5, 2024"},"absolute_dates_time":{"created":"Posted on Apr 5, 2024 12:12 pm","modified":"Updated on Apr 5, 2024 12:12 pm"},"featured_img_caption":"fanapt-for-bipolar-disorder-treatment","series_order":"","_links":{"self":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/27477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/comments?post=27477"}],"version-history":[{"count":0,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/27477\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media\/27478"}],"wp:attachment":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media?parent=27477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/categories?post=27477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/tags?post=27477"},{"taxonomy":"industry","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/industry?post=27477"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/therapeutic_areas?post=27477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}