{"id":34961,"date":"2026-04-07T17:26:00","date_gmt":"2026-04-07T11:56:00","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=34961"},"modified":"2026-04-07T14:26:58","modified_gmt":"2026-04-07T08:56:58","slug":"pharma-news-for-neurocrine-astrazeneca-immunovant","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/pharma-news-for-neurocrine-astrazeneca-immunovant","title":{"rendered":"Neurocrine Signs Deal to Acquire Soleno Therapeutics; AstraZeneca Shares Favorable Results from EMERALD-3 Study in Liver Cancer; Immunovant Presents Phase 3 Clinical Data for Batoclimab in TED; Alto Neuroscience Shares Topline Findings from Phase 2 ALTO-101 Study and Pipeline Updates; ORIC Positions Rinzimetostat for Phase 3 Success with Optimized Dosing Strategy"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_76 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69d53a902e4de\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69d53a902e4de\"  aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-news-for-neurocrine-astrazeneca-immunovant\/#Neurocrine_Announces_Acquisition_of_Soleno_Therapeutics_to_Broaden_Rare_Disease_Portfolio\" >Neurocrine Announces Acquisition of Soleno Therapeutics to Broaden Rare Disease Portfolio<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-news-for-neurocrine-astrazeneca-immunovant\/#AstraZeneca_Announces_Positive_EMERALD-3_Trial_Outcomes_in_HCC\" >AstraZeneca Announces Positive EMERALD-3 Trial Outcomes in HCC<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-news-for-neurocrine-astrazeneca-immunovant\/#Immunovant_Reports_Phase_3_Results_for_Batoclimab_in_Thyroid_Eye_Disease\" >Immunovant Reports Phase 3 Results for Batoclimab in Thyroid Eye Disease<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-news-for-neurocrine-astrazeneca-immunovant\/#Alto_Neuroscience_Presents_Phase_2_Proof-of-Concept_Results_for_ALTO-101_and_Pipeline_Insights\" >Alto Neuroscience Presents Phase 2 Proof-of-Concept Results for ALTO-101 and Pipeline Insights<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-news-for-neurocrine-astrazeneca-immunovant\/#ORIC_Advances_Rinzimetostat_Combination_into_Phase_3_Himalayas-1_Study\" >ORIC Advances Rinzimetostat Combination into Phase 3 Himalayas-1 Study<\/a><\/li><\/ul><\/nav><\/div>\n\n<h2 class=\"wp-block-heading\" id=\"h-neurocrine-announces-acquisition-of-soleno-therapeutics-to-broaden-rare-disease-portfolio\"><span class=\"ez-toc-section\" id=\"Neurocrine_Announces_Acquisition_of_Soleno_Therapeutics_to_Broaden_Rare_Disease_Portfolio\"><\/span>Neurocrine Announces Acquisition of Soleno Therapeutics to Broaden Rare Disease Portfolio<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Neurocrine Biosciences<\/strong> has entered into a definitive agreement to acquire <strong>Soleno Therapeutics<\/strong> in a transaction valued at approximately <strong>$2.9 billion<\/strong>, marking a significant strategic expansion into the rare disease and metabolic disorder space. This acquisition brings Soleno\u2019s lead asset, <strong>VYKAT XR (diazoxide choline extended-release tablets)<\/strong>, into Neurocrine\u2019s portfolio.&nbsp;<\/p>\n\n\n\n<p>The therapy is approved for the treatment of hyperphagia associated with <a href=\"https:\/\/www.delveinsight.com\/report-store\/prader-willi-syndrome-market\">Prader-Willi syndrome (PWS)<\/a>, a rare and complex genetic disorder characterized by insatiable hunger and severe obesity risk. The addition of VYKAT XR not only strengthens Neurocrine\u2019s commercial product lineup but also aligns with its long-term strategy of addressing high unmet medical needs in underserved patient populations.&nbsp;<\/p>\n\n\n\n<p>The company expects the acquisition to be immediately accretive to revenue growth while also offering opportunities for lifecycle management and label expansion. Neurocrine emphasized that the integration of Soleno\u2019s capabilities will enhance its expertise in endocrinology and rare disease therapeutics. Furthermore, the deal underscores increasing consolidation trends within the biotech sector, where established players are acquiring innovative smaller firms to diversify pipelines and reduce reliance on single-product revenues.&nbsp;<\/p>\n\n\n\n<p>With this move, Neurocrine aims to improve patient access to innovative therapies while leveraging its commercial infrastructure to maximize global reach. The transaction is subject to customary closing conditions and regulatory approvals, with completion anticipated in the near term.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-astrazeneca-announces-positive-emerald-3-trial-outcomes-in-hcc\"><span class=\"ez-toc-section\" id=\"AstraZeneca_Announces_Positive_EMERALD-3_Trial_Outcomes_in_HCC\"><\/span>AstraZeneca Announces Positive EMERALD-3 Trial Outcomes in HCC<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>AstraZeneca <\/strong>has announced positive results from its <strong>Phase 3 EMERALD-3 clinical trial<\/strong> evaluating the combination of <strong>IMFINZI <\/strong>(durvalumab) and <strong>IMJUDO <\/strong>(tremelimumab) alongside standard therapies in patients with unresectable hepatocellular carcinoma (HCC). The trial successfully met its primary endpoint, demonstrating a statistically significant improvement in progression-free survival compared to current standard-of-care treatments.&nbsp;<\/p>\n\n\n\n<p>These findings represent a meaningful advancement in the <a href=\"https:\/\/www.delveinsight.com\/report-store\/liver-cancer-market\">treatment landscape of liver cancer<\/a>, which remains one of the leading causes of cancer-related mortality worldwide. In addition to progression-free survival benefits, early trends in overall survival were also observed, suggesting the potential for long-term clinical impact.&nbsp;<\/p>\n\n\n\n<p>The safety profile of the combination therapy was consistent with previously reported data, with no new safety signals identified, reinforcing its suitability for broader clinical use. AstraZeneca highlighted that this regimen could redefine first-line treatment standards for patients with advanced liver cancer, particularly those who are not eligible for surgical intervention.&nbsp;<\/p>\n\n\n\n<p>The company plans to present detailed results at upcoming medical conferences and engage with global regulatory authorities to support potential approvals. These results further strengthen AstraZeneca\u2019s oncology portfolio and its leadership in immuno-oncology, demonstrating continued commitment to developing innovative combination therapies that enhance patient outcomes. The study also reflects growing momentum in leveraging immune checkpoint inhibitors to improve survival in difficult-to-treat cancers.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-immunovant-reports-phase-3-results-for-batoclimab-in-thyroid-eye-disease\"><span class=\"ez-toc-section\" id=\"Immunovant_Reports_Phase_3_Results_for_Batoclimab_in_Thyroid_Eye_Disease\"><\/span>Immunovant Reports Phase 3 Results for Batoclimab in Thyroid Eye Disease<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Immunovant <\/strong>has reported positive <strong>Phase 3 clinical trial<\/strong> results for <strong>batoclimab<\/strong>, an investigational monoclonal antibody targeting the <a href=\"https:\/\/www.delveinsight.com\/report-store\/fcrn-inhibitor-competitive-landscape-and-market-forecast\">neonatal Fc receptor (FcRn)<\/a>, designed to reduce circulating levels of pathogenic immunoglobulin G (IgG) antibodies. The study demonstrated significant clinical improvements across key efficacy endpoints in patients with autoimmune disorders, reinforcing the therapeutic potential of FcRn inhibition as a novel treatment approach.&nbsp;<\/p>\n\n\n\n<p>Batoclimab showed rapid and sustained reductions in IgG levels, translating into measurable symptom relief and improved patient-reported outcomes. The safety profile observed in the trial was generally consistent with previous studies, supporting its continued development across multiple indications. Immunovant emphasized that these findings validate its scientific approach and strengthen its position within the competitive autoimmune treatment landscape.&nbsp;<\/p>\n\n\n\n<p>The company is advancing batoclimab across a range of autoimmune diseases, including <a href=\"https:\/\/www.delveinsight.com\/report-store\/myasthenia-gravis-market\">myasthenia gravis<\/a> and thyroid eye disease, where current treatment options remain limited or suboptimal. The results also highlight the broader potential of FcRn-targeting therapies to transform the management of chronic immune-mediated conditions by addressing underlying disease mechanisms rather than merely alleviating symptoms.&nbsp;<\/p>\n\n\n\n<p>Immunovant plans to engage with regulatory authorities to discuss next steps, including potential submission strategies and further clinical development. The success of batoclimab underscores growing industry interest in targeted immunology therapies and positions Immunovant as a key player in the next generation of autoimmune disease treatments.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-alto-neuroscience-presents-phase-2-proof-of-concept-results-for-alto-101-and-pipeline-insights\"><span class=\"ez-toc-section\" id=\"Alto_Neuroscience_Presents_Phase_2_Proof-of-Concept_Results_for_ALTO-101_and_Pipeline_Insights\"><\/span>Alto Neuroscience Presents Phase 2 Proof-of-Concept Results for ALTO-101 and Pipeline Insights<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Alto Neuroscience<\/strong> has announced topline results from its <strong>Phase 2 proof-of-concept clinical trial <\/strong>evaluating <strong>ALTO-101<\/strong>, an investigational therapy aimed at treating neuropsychiatric conditions using a precision medicine approach. The study demonstrated promising efficacy signals in specific patient subgroups identified through biomarker-based stratification, highlighting the importance of personalized treatment strategies in psychiatry.&nbsp;<\/p>\n\n\n\n<p>Unlike traditional approaches that rely on generalized treatment methods, Alto\u2019s platform integrates neurobiological data to match patients with therapies most likely to be effective for their unique profiles. The results showed meaningful improvements in targeted populations, supporting the hypothesis that precision psychiatry can enhance clinical outcomes and reduce trial-and-error prescribing. ALTO-101 was well tolerated, with a safety profile consistent with expectations, further supporting its continued development.&nbsp;<\/p>\n\n\n\n<p>Alto Neuroscience emphasized that these findings validate its broader pipeline strategy, which focuses on developing differentiated therapies guided by objective biomarkers. The company continues to advance multiple programs across depression, <a href=\"https:\/\/www.delveinsight.com\/report-store\/schizophrenia-market\">schizophrenia<\/a>, and other neuropsychiatric disorders, aiming to address significant unmet needs in mental healthcare.&nbsp;<\/p>\n\n\n\n<p>These advancements come at a time when the global burden of mental illness is rising, underscoring the need for more effective and personalized interventions. Alto plans to use these results to inform future trial designs and expand its research efforts, reinforcing its commitment to transforming psychiatric treatment through innovation and data-driven approaches.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-oric-advances-rinzimetostat-combination-into-phase-3-himalayas-1-study\"><span class=\"ez-toc-section\" id=\"ORIC_Advances_Rinzimetostat_Combination_into_Phase_3_Himalayas-1_Study\"><\/span>ORIC Advances Rinzimetostat Combination into Phase 3 Himalayas-1 Study<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>ORIC Pharmaceuticals<\/strong> has announced the selection of <strong>rinzimetostat <\/strong>as its recommended <strong>Phase 3 candidate<\/strong>, marking a key milestone in the company\u2019s oncology pipeline. Rinzimetostat is a potent inhibitor targeting specific epigenetic regulators implicated in cancer progression, particularly in tumors driven by genetic alterations that confer treatment resistance.&nbsp;<\/p>\n\n\n\n<p>The decision to advance this candidate into late-stage development is based on encouraging clinical data demonstrating promising anti-tumor activity and a manageable safety profile in early-phase studies. ORIC highlighted that rinzimetostat has shown potential in genetically defined patient populations, supporting a precision oncology approach that aims to deliver more effective and targeted therapies.&nbsp;<\/p>\n\n\n\n<p>The company plans to initiate Phase 3 trials to further evaluate efficacy and safety in larger patient cohorts, with a focus on improving outcomes in cancers that have limited treatment options. This advancement reflects ORIC\u2019s broader strategy of developing therapies that overcome resistance mechanisms, a major challenge in cancer treatment. The selection of rinzimetostat also underscores the growing importance of epigenetic therapies in oncology, offering new avenues for intervention beyond traditional chemotherapy and targeted therapies.&nbsp;<\/p>\n\n\n\n<p>ORIC remains committed to advancing innovative treatments that address unmet medical needs, and this milestone positions the company for potential future regulatory submissions. The development of rinzimetostat represents a significant step toward expanding therapeutic options for patients with difficult-to-treat cancers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neurocrine Announces Acquisition of Soleno Therapeutics to Broaden Rare Disease Portfolio Neurocrine Biosciences has entered into a definitive agreement to acquire Soleno Therapeutics in a transaction valued at approximately $2.9 billion, marking a significant strategic expansion into the rare disease and metabolic disorder space. This acquisition brings Soleno\u2019s lead asset, VYKAT XR (diazoxide choline extended-release [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":34962,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[32],"tags":[1898,22084,349,4243,639,21116,1519],"industry":[17225],"therapeutic_areas":[17238,17228],"class_list":["post-34961","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-notizia","tag-fcrn","tag-fcrn-inhibitor","tag-latest-pharma-news","tag-liver-cancer","tag-pharma-news","tag-prader-willi-syndrome","tag-schizophrenia","industry-pharmaceutical","therapeutic_areas-genetic-disorders","therapeutic_areas-oncology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v25.8) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pharma News | Neurocrine, AstraZeneca, Immunovant<\/title>\n<meta name=\"description\" content=\"Neurocrine\u2019s Soleno Acquisition; AstraZeneca\u2019s EMERALD-3 Study Results; Immunovant\u2019s Batoclimab; Alto Neuroscience\u2019s Phase 2 ALTO-101 Study\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.delveinsight.com\/blog\/pharma-news-for-neurocrine-astrazeneca-immunovant\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pharma News | Neurocrine, AstraZeneca, Immunovant\" \/>\n<meta property=\"og:description\" content=\"Neurocrine\u2019s Soleno Acquisition; AstraZeneca\u2019s EMERALD-3 Study Results; Immunovant\u2019s Batoclimab; Alto Neuroscience\u2019s Phase 2 ALTO-101 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Joshi","author_link":"https:\/\/www.delveinsight.com\/blog\/author\/sjoshidelveinsight-com"},"featured_img":"https:\/\/www.delveinsight.com\/blog\/wp-content\/uploads\/2026\/04\/pharma-news-for-neurocrine-astrazeneca-immunovant-300x187.webp","coauthors":[],"tax_additional":{"categories":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Notizia - Recent Pharma, Healthcare and Biotech Happenings<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Notizia - Recent Pharma, Healthcare and Biotech Happenings<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">FcRn<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">FcRn Inhibitor<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Latest pharma news<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Liver cancer<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">pharma news<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Prader-Willi Syndrome<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">schizophrenia<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">FcRn<\/span>","<span class=\"advgb-post-tax-term\">FcRn Inhibitor<\/span>","<span class=\"advgb-post-tax-term\">Latest pharma news<\/span>","<span class=\"advgb-post-tax-term\">Liver cancer<\/span>","<span class=\"advgb-post-tax-term\">pharma news<\/span>","<span class=\"advgb-post-tax-term\">Prader-Willi Syndrome<\/span>","<span class=\"advgb-post-tax-term\">schizophrenia<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 15 minutes ago","modified":"Updated 3 hours ago"},"absolute_dates":{"created":"Posted on Apr 7, 2026","modified":"Updated on Apr 7, 2026"},"absolute_dates_time":{"created":"Posted on Apr 7, 2026 5:26 pm","modified":"Updated on Apr 7, 2026 2:26 pm"},"featured_img_caption":"pharma-news-for-neurocrine-astrazeneca-immunovant","series_order":"","_links":{"self":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/34961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/comments?post=34961"}],"version-history":[{"count":1,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/34961\/revisions"}],"predecessor-version":[{"id":34963,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/34961\/revisions\/34963"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media\/34962"}],"wp:attachment":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media?parent=34961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/categories?post=34961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/tags?post=34961"},{"taxonomy":"industry","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/industry?post=34961"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/therapeutic_areas?post=34961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}