{"id":3847,"date":"2018-12-20T15:44:53","date_gmt":"2018-12-20T10:14:53","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=3847"},"modified":"2022-10-13T11:01:55","modified_gmt":"2022-10-13T05:31:55","slug":"attention-deficit-hyperactivity-disorder-adhd","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/attention-deficit-hyperactivity-disorder-adhd","title":{"rendered":"Attention-Deficit\/Hyperactivity Disorder (ADHD)"},"content":{"rendered":"\n<p class=\"has-drop-cap\"><strong>Attention-deficit\/hyperactivity disorder (ADHD)<\/strong> is a brain disorder marked by an ongoing pattern of inattention and\/or hyperactivity-impulsivity that interferes with functioning or development. ADHD is a group of behaviors. It is also called as <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/attention-deficit-hyperactivity-disorder-adhd-market\">attention deficit disorder (ADD)<\/a><\/strong>. Attention deficit hyperactivity disorder (ADHD) is a behavioral disorder that includes symptoms such as <strong>inattentiveness, hyperactivity and impulsiveness<\/strong>. <strong><em>Inattentiveness<\/em> <\/strong>is marked when a person wanders off task, lacks persistence, has difficulty in sustaining focus, and is disorganized. <strong><em>Hyperactivity<\/em><\/strong> is characterized when a person seems to move about constantly, including in situations in which it is not appropriate; or excessively fidgets, taps, or talks. In adults, it may be extreme restlessness or wearing others out with constant activity. On the other hand, <strong><em>Impulsivity<\/em><\/strong> means a person makes hasty actions that occur in the moment without first thinking about them and that may have high potential for harm; or a desire for immediate rewards or inability to delay gratification.<\/p>\n\n\n\n<p><strong>The Diagnostic and Statistical Manual of Mental Disorders &#8211; 5th\nedition (DSM-5TM) <\/strong>has categorized ADHD into three subtypes: <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong><em>ADHD predominantly inattentive type: <\/em><\/strong>if\nthe individual meets the criteria for inattention, but not the criteria for\nhyperactivity-impulsivity, for the past six months<\/li><li><strong><em>ADHD predominantly hyperactive-impulsive type: <\/em><\/strong>if\nthe child meets the criteria for hyperactivity-impulsivity, but not the\ncriteria for inattention, in the past six months<\/li><li><strong><em>ADHD combined type: <\/em><\/strong>if a person\nmeets the criteria for both inattention and hyperactivity-impulsivity for the\npast six months. Symptoms of the above two types are equally present in the\nperson<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-media-text alignwide\" style=\"grid-template-columns:34% auto\"><figure class=\"wp-block-media-text__media\"><img decoding=\"async\" width=\"332\" height=\"316\" src=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2018\/12\/15171538\/Capture.png\" alt=\"Attention-Deficit\/Hyperactivity Disorder\" class=\"wp-image-3848 size-full\" srcset=\"https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2018\/12\/15171538\/Capture.png 332w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2018\/12\/15171538\/Capture-300x286.png 300w, https:\/\/assets.delveinsight.com\/blog\/wp-content\/uploads\/2018\/12\/15171538\/Capture-20x20.png 20w\" sizes=\"(max-width: 332px) 100vw, 332px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p><em>According to<\/em><strong><em>DelveInsight\u2019s estimates, total diagnosed prevalent population<\/em><\/strong><em>in the<\/em><strong><em>7MM<\/em><\/strong><em>was <strong>approximately<\/strong><\/em><strong><em>29,069,744<\/em><\/strong><em>in 2016, and is expected to grow at a CAGR of 0.74% for the study period <strong>[2016-2027]<\/strong>. Higher prevalence of Attention-deficit\/hyperactivity disorder is observed in the United States. Among the European 5 countries, France had the highest prevalent cases of ADHD, followed by Italy. On the other hand, Germany had the lowest prevalent population in 2016. Japan accounted for 11% of the diagnosed prevalent population of ADHD in 2016. <\/em><\/p>\n<\/div><\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><em>Based on the\nDelveInsight\u2019s analysis, the <strong>gender-specific\n<\/strong>data revealed that<strong> males <\/strong>were<strong> more affected <\/strong>than females, both in\ncase of <strong>children and adults<\/strong>.\nFurthermore, DelveInsight has gone further to categorize the ADHD data into\nthree subtypes namely: Inattentive Type; Hyperactive\/impulsive type and\nCombined type. In terms of sub-type specific data of the disease, most of the\ndiagnosed prevalent population belongs to <strong>Combined\nType ADHD<\/strong>.&nbsp; <\/em><\/p>\n\n\n\n<p><strong><em>Correct\ndiagnosis<\/em><\/strong> and <strong><em>under-treatment<\/em><\/strong> for the <strong>adult\nADHD<\/strong> patients are the <strong>unmet needs<\/strong>\nfor the indication. Currently, no straight forward diagnostic technique is available\nin the market. A detailed assessment is required by the medical professionals\nfrom different domains to confirm Attention Deficit Hyperactivity Disorder in\nan individual. In addition, there is a requirement for the <strong><em>availability of non-stimulant\nmedication<\/em><\/strong> and <strong><em>management<\/em><\/strong> therapies <strong>with fewer side effects<\/strong>. There is a\nsignificant need for non-stimulant ADHD treatments in the marketplace,\nespecially in light of recent regulatory oversight of abuse of currently\napproved treatments. <strong><em>Challenging discrimination<\/em><\/strong> also adds\nto the unmet needs. Many a times people fail to distinguish between the\nsymptoms of ADHD and the casual hyperactivity and impulsivity of the child.\nSituations like these creates confusion and makes it even more challenging.<\/p>\n\n\n\n<p>Treatments\ninclude <strong><em>Medication, Psychotherapy, Education or Training, or a Combination of\nTreatments<\/em><\/strong>. Medications aim to reduce the symptoms of Attention-Deficit\nHyperactivity Disorder. The medication prescribed by the doctor may be\nlong-acting formulations administered as a single daily dose or short-acting\nformulations for the individuals not benefited from long-acting formulations. The\nmost common medication prescribed by the health care experts are <strong><em>Stimulants<\/em><\/strong>.<\/p>\n\n\n\n<p>Stimulant\nmedications<strong><em> (methylphenidate, amphetamine, Dextroamphetamine, Lisdexamfetamine\nderivatives)<\/em><\/strong> are <strong><em>first-line treatment<\/em><\/strong>. The stimulants\nwork by increasing the dopamine and norepinephrine levels that further increase\nalertness, attention, and energy, as well as elevate blood pressure, heart rate,\nand respiration. The <strong><em>second line of treatment<\/em><\/strong> comprises\nof <strong><em>Non-Stimulants\n<\/em><\/strong>including <strong><em>atomoxetine and Alpha-2 adrenergic agonists<\/em><\/strong> form <strong><em>second-line\nmanagement<\/em><\/strong>. Such medications prescribed by the medical professional\nmight take a little longer to show an impact. These are advised either when a\npatient is not benefited by the stimulants or when the individual is troubled\nby the bothersome side effects of the stimulants. Sometimes, the non-stimulants\nare also taken in combination with the stimulants to increase the effectiveness\nof the therapy. The other non- stimulants also include <strong><em>Antidepressants,<\/em><\/strong> which\nare used to treat anxiety, pain and insomnia in addition to depression.\nAlthough antidepressants are not FDA-approved specifically to treat ADHD,\nantidepressants are sometimes used to treat ADHD in adults. These are sometimes\nused as <strong><em>off-label therapies<\/em><\/strong> in the market.<\/p>\n\n\n\n<p>Adding\n<strong><em>psychotherapy<\/em><\/strong>\n(sometimes called \u201ctalk therapy\u201d) to treat ADHD can help patients and their\nfamilies to better cope with everyday problems. Psychotherapy is a term for a\nvariety of treatment techniques that aim to help a person identify and change\ntroubling emotions, thoughts, and behavior. Most psychotherapy takes place with\na licensed and trained mental health care professional and a patient meeting\none on one or with other patients in a group setting.<\/p>\n\n\n\n<p>The\noverall dynamics of ADHD market is anticipated to change in the coming years in\nregard to the expected launch of potential therapies in the near future. <strong>SPN-812, SPN-810, Dasotraline, centanafadine,\nKP415, KP484<\/strong> are currently in the <strong>Phase\nIII<\/strong> stage of development followed by <strong>AEVI-001,\nNLS-1, Eltoprazine, CX717 <\/strong>in <strong>phase\nII<\/strong> clinical development. SPN-810 has received fast track designation with\npositive phase II results. Therefore, the product hold a bright chance to be\nlaunched in the market in 2021. The other phase III product SPN-812 has also\nshown positive results. The two potential candidate of Kempharm KP415 and KP484\ncan also be considered as upcoming products in 2020. Also, Dasotraline is\nexpected to hit the market in 2021 for adult and pediatric population. <\/p>\n\n\n\n<p>The\nnumber of companies working actively for the development of therapeutic options\nfor Attention Deficit Hyperactivity Disorder are quite high in number. Multiple\nproducts from many companies like <strong><em>Sumitomo Dainippon Pharma, Supernus\nPharmaceuticals, Kempharm<\/em><\/strong>, etc. are being clinically developed and\ntested in the late and mid stages of developments. Therefore, the companies\nproceeding in this direction hold a bright and a positive chance to capture the\nmarket share once approved. Many <strong><em>key players<\/em><\/strong> are focused on <strong><em>developing\nnon-stimulants<\/em><\/strong> to overcome the side effects and drug abuse associated\nwith the stimulants. The upcoming non stimulant therapeutic options will drive\nthe market positively. Overall, the increasing prevalence of the disease along\nwith the <strong><em>promising emerging pipeline<\/em><\/strong> therapies will <strong><em>fuel the market<\/em><\/strong> during\nthe forecast period of 2018-2027.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Attention-deficit\/hyperactivity disorder (ADHD) is a brain disorder marked by an ongoing pattern of inattention and\/or hyperactivity-impulsivity that interferes with functioning or development. ADHD is a group of behaviors. It is also called as attention deficit disorder (ADD). Attention deficit hyperactivity disorder (ADHD) is a behavioral disorder that includes symptoms such as inattentiveness, hyperactivity and impulsiveness. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3855,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[17,17434],"tags":[16250,17690,19300,17689],"industry":[17225],"therapeutic_areas":[17229],"class_list":["post-3847","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","category-facts-and-figures","tag-adhd","tag-adhd-market","tag-attention-deficit-hyperactivity-disorder-3","tag-hyperactivity","industry-pharmaceutical","therapeutic_areas-central-nervous-system"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v25.8) - 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href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Articles<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Facts and Figures<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Articles<\/span>","<span class=\"advgb-post-tax-term\">Facts and Figures<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">ADHD<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">ADHD Market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Attention-deficit\/hyperactivity disorder<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Hyperactivity<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">ADHD<\/span>","<span class=\"advgb-post-tax-term\">ADHD 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