{"id":4127,"date":"2019-02-19T17:35:16","date_gmt":"2019-02-19T12:05:16","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=4127"},"modified":"2021-07-24T12:57:13","modified_gmt":"2021-07-24T07:27:13","slug":"notizia-91","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/notizia-91","title":{"rendered":"Notizia"},"content":{"rendered":"\n<p class=\"has-background has-very-light-gray-background-color\"><strong>CRISPR treatment delivers benefits in mice<\/strong><\/p>\n\n\n\n<p><br> The researchers from <strong>Duke University<\/strong> along with drugmaker <strong>Sarepta Therapeutics<\/strong> published a report stating that a single change in the genetic system of <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/duchenne-muscular-dystrophy-market-insight-epidemiology-and-market-forecast\">Duchenne muscular dystrophy (DMD)<\/a><\/strong> affected mice, using <strong>CRISPR <\/strong>gene editing tool resulted in increasing their life span by one year. No toxic immune responses were exhibited to <strong>Cas9 enzyme<\/strong> used for <strong>gene editing<\/strong>.  <\/p>\n\n\n\n<p class=\"has-background has-very-light-gray-background-color\"> <strong>A step ahead in treating metastatic Kidney Cancer<\/strong><\/p>\n\n\n\n<p>Drug makers <strong>Merck &amp; Co.<\/strong> and <strong>Pfizer<\/strong> conducted trials giving thumbs up to pair<strong> immunotherapy<\/strong> with a type of targeted drug to treat<strong><a href=\"https:\/\/www.delveinsight.com\/blog\/most-common-cancers\/\"> metastatic Kidney Cancer.<\/a><\/strong> In trials, patients who received Merck&#8217;s<strong> Keytruda<\/strong> and Pfizer&#8217;s <strong>Bavencio<\/strong> together showed increased chances of survival as compared to those given only <strong>Sutent<\/strong>. <\/p>\n\n\n\n<p class=\"has-background has-very-light-gray-background-color\"><g class=\"gr_ gr_12 gr-alert gr_gramm gr_inline_cards gr_run_anim Grammar only-ins replaceWithoutSep\" id=\"12\" data-gr-id=\"12\"><strong>University<\/strong><\/g><strong> of Louisville develops a drug to target <\/strong><g class=\"gr_ gr_13 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"13\" data-gr-id=\"13\"><strong>tumors<\/strong><\/g><\/p>\n\n\n\n<p><br>Researchers at<strong> University of Louisville <\/strong>have developed a drug<strong> SA-4-1BBL,<\/strong> which when used in concurrence with <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/t-cell-inhibitor-pipeline-insight\">adaptive T-cells<\/a><\/strong> can largely shield from <g class=\"gr_ gr_14 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling multiReplace\" id=\"14\" data-gr-id=\"14\">tumors<\/g>. The novel drug activates <strong>CD4+ T cells<\/strong> and <strong>Natural Killer cells <\/strong>which have the power to destroy <g class=\"gr_ gr_12 gr-alert gr_gramm gr_inline_cards gr_disable_anim_appear Grammar only-del replaceWithoutSep\" id=\"12\" data-gr-id=\"12\">the <g class=\"gr_ gr_11 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace\" id=\"11\" data-gr-id=\"11\">cancer<\/g><\/g><g class=\"gr_ gr_11 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling ins-del multiReplace\" id=\"11\" data-gr-id=\"11\"> causing<\/g> cells in the body even before they get settled. <\/p>\n\n\n\n<p class=\"has-background has-very-light-gray-background-color\"><strong>Bayer and Orion <\/strong><g class=\"gr_ gr_9 gr-alert gr_gramm gr_inline_cards gr_disable_anim_appear Grammar multiReplace\" id=\"9\" data-gr-id=\"9\"><strong>develop<\/strong><\/g><strong> a therapy to beat Prostate Cancer<\/strong><\/p>\n\n\n\n<p><br>Drug makers <strong>Bayer<\/strong> and <strong>Orion <\/strong>are jointly developing a therapy to enhance metastasis-free survival. Trials were conducted, which revealed that when <strong>Darolutamide<\/strong> added with<strong> Androgen Deprivation Therapy (ADT)<\/strong>, showed <strong>59 <\/strong><g class=\"gr_ gr_10 gr-alert gr_spell gr_inline_cards gr_disable_anim_appear ContextualSpelling multiReplace\" id=\"10\" data-gr-id=\"10\"><strong>percent<\/strong><\/g><strong> <\/strong>decline in the probability of deaths caused than in Placebo with ADT in the patients affected by <strong><a href=\"https:\/\/www.delveinsight.com\/report-store\/metastatic-prostate-cancer-market\">Prostate Cancer<\/a><\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CRISPR treatment delivers benefits in mice The researchers from Duke University along with drugmaker Sarepta Therapeutics published a report stating that a single change in the genetic system of Duchenne muscular dystrophy (DMD) affected mice, using CRISPR gene editing tool resulted in increasing their life span by one year. No toxic immune responses were exhibited [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4047,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[32],"tags":[137,2582,2295,1079,460,498,2581],"industry":[17225],"therapeutic_areas":[17235,17238,17228,17234],"class_list":["post-4127","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-notizia","tag-cancer","tag-cas9-enzyme","tag-duke-university","tag-natural-killer-cells","tag-pfizer","tag-prostate-cancer","tag-sarepta-therapeutics","industry-pharmaceutical","therapeutic_areas-cell-and-gene-therapy","therapeutic_areas-genetic-disorders","therapeutic_areas-oncology","therapeutic_areas-rare-diseases"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.8 (Yoast SEO v25.8) - 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Recent Pharma, Healthcare and Biotech Happenings<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Notizia - Recent Pharma, Healthcare and Biotech Happenings<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Cancer<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Cas9 enzyme<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Duke University<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Natural killer cells<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Pfizer<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Prostate Cancer<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/notizia\/\" class=\"advgb-post-tax-term\">Sarepta Therapeutics<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Cancer<\/span>","<span class=\"advgb-post-tax-term\">Cas9 enzyme<\/span>","<span class=\"advgb-post-tax-term\">Duke University<\/span>","<span class=\"advgb-post-tax-term\">Natural killer cells<\/span>","<span class=\"advgb-post-tax-term\">Pfizer<\/span>","<span class=\"advgb-post-tax-term\">Prostate Cancer<\/span>","<span class=\"advgb-post-tax-term\">Sarepta Therapeutics<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 7 years ago","modified":"Updated 5 years ago"},"absolute_dates":{"created":"Posted on Feb 19, 2019","modified":"Updated on Jul 24, 2021"},"absolute_dates_time":{"created":"Posted on Feb 19, 2019 5:35 pm","modified":"Updated on Jul 24, 2021 12:57 pm"},"featured_img_caption":"Kidney Cancer","series_order":"","_links":{"self":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/4127","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/comments?post=4127"}],"version-history":[{"count":0,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/posts\/4127\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media\/4047"}],"wp:attachment":[{"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/media?parent=4127"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/categories?post=4127"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/tags?post=4127"},{"taxonomy":"industry","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/industry?post=4127"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/www.delveinsight.com\/blog\/wp-json\/wp\/v2\/therapeutic_areas?post=4127"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}