{"id":5903,"date":"2019-09-05T16:56:16","date_gmt":"2019-09-05T11:26:16","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=5903"},"modified":"2021-07-24T12:57:31","modified_gmt":"2021-07-24T07:27:31","slug":"recent-pharma-happenings-vertex-acquires-semma-biomotiv-bms","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/recent-pharma-happenings-vertex-acquires-semma-biomotiv-bms","title":{"rendered":"Vertex acquires Semma; Luxturna gets approval for rare eye disorder"},"content":{"rendered":"\n

Vertex Pharmaceuticals recently has announced the acquisition of Semma Therapeutics for USD 950 million in cash. <\/strong><\/h4>\n\n\n\n

Vertex Pharmaceuticals, aimed at creating therapies for life-threatening diseases, like cystic fibrosis<\/a>, has signed a definitive agreement with Semma therapeutics, working to bring in the Healthcare market a new innovative treatment option for the diabetes patient pool. <\/p>\n\n\n\n

Surveys revealed that approximately 1.25 million Americans are living with Type 1 diabetes. And by 2050, 5 million people are expected to be diagnosed with Type 1 diabetes<\/a>.<\/p>\n\n\n\n

Semma has successfully advanced in producing large quantities of functional human pancreatic <\/a>beta cells to treat hypoglycemia <\/a>by regulating the insulin secretion and a device to protect these cells from any immune response.<\/p>\n\n\n\n

Through the agreement, Vertex\nwill get a hold of both of Semma\u2019s preclinical products, a stem cell\nmanufacturing process and a novel delivery system via the device. <\/p>\n\n\n\n

Patients affected by a rare inherited eye disorder now will be able to\naccess a new treatment option in the form of Gene therapy. <\/strong><\/h4>\n\n\n\n

The UK\u2019s National Institute for Health and Care Excellence (NICE) has given its recommendation for the use of Novartis\u2019 gene therapy Luxturna (voretigene neparvovec) to treat rare inherited retinal dystrophies. <\/p>\n\n\n\n

Luxturna, originally developed by Spark Therapeutics, is an adeno-associated virus vector-based gene therapy. Indicated for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy.<\/p>\n\n\n\n

In the therapy, the gene is\ndirectly injected into the eye directly to restore the vision. <\/p>\n\n\n\n

At the moment, there exists no standard cure for inherited retinal dystrophy. It leads to a loss of vision to a point of total blindness. The most common retinal dystrophy, Retinitis pigmentosa<\/a> (RP) has a prevalence of roughly 1:4,000.<\/p>\n\n\n\n

According to DelveInsight, the Retinitis Pigmentosa therapeutic market <\/a>in the 7MM is expected to grow by 2028 driven at a Compound Annual Growth Rate (CAGR) of 28.90%. <\/p>\n\n\n\n

In contrast to EU5 and the USA,\nJapan\u2019s Retinitis pigmentosa therapy market, so far, has been dominated by the\nuse of Luxturna. <\/p>\n\n\n\n

As per the assessments by\nDelveInsight\u2019s analysts, the market shares of prescription therapies were found\nto be USD 133.82 million in 2017.<\/p>\n\n\n\n

Despite the approval of the gene\ntherapy and the emerging therapies, the market size of the supportive therapies\nwill continue to grow due to the fact that therapies to treat all types and\nsubsequent subtypes have not yet been developed, and therefore a significant\nnumber of patient population will continue to be prescribed supportive\ntherapies as a management practice. <\/p>\n\n\n\n

Bristol-Myers Squibb has announced a strategic partnership with a drug development\naccelerator BioMotiv, to advance breakthrough drug discoveries. <\/strong><\/h4>\n\n\n\n

The partnership will augment the ability of both organizations to develop novel advanced and innovative therapies for the patient pool. <\/p>\n\n\n\n

Under the terms of the agreement, Bristol-Myers Squibb (BMS) will have an option to invest funds in specific projects of interest.  The companies have decided to fund and develop novel therapeutics in the field of disease that has unmet needs and poor standards of therapies. Moreover, the partnership will allow BMS to acquire the company solely upon the identification of new molecules for treating any indication. <\/p>\n\n\n\n

Bristol-Myers Squibb isn\u2019t the first one to form the partnership to advance the drug discovery with BioMotiv. Other global pharma leaders that are already in the collaboration with BioMotiv are Takeda Pharmaceuticals, Biogen, Arix Bioscience and Charles River Laboratories. <\/p>\n","protected":false},"excerpt":{"rendered":"

Vertex Pharmaceuticals recently has announced the acquisition of Semma Therapeutics for USD 950 million in cash. Vertex Pharmaceuticals, aimed at creating therapies for life-threatening diseases, like cystic fibrosis, has signed a definitive agreement with Semma therapeutics, working to bring in the Healthcare market a new innovative treatment option for the diabetes patient pool. Surveys revealed […]<\/p>\n","protected":false},"author":1,"featured_media":5906,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[32],"tags":[423,639],"industry":[17225],"therapeutic_areas":[17244],"class_list":["post-5903","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-notizia","tag-novartis","tag-pharma-news","industry-pharmaceutical","therapeutic_areas-ophthalmology"],"acf":[],"yoast_head":"\nVertex acquires Semma; BMS's partnership; Gene therapy updates<\/title>\n<meta name=\"description\" content=\"According to DelveInsight, the Retinitis Pigmentosa therapeutic market in the 7MM is expected to grow by 2028 driven at 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