{"id":9420,"date":"2020-05-25T18:11:39","date_gmt":"2020-05-25T12:41:39","guid":{"rendered":"https:\/\/www.delveinsight.com\/blog\/?p=9420"},"modified":"2025-05-08T13:56:45","modified_gmt":"2025-05-08T08:26:45","slug":"immune-thrombocytopenia-market","status":"publish","type":"post","link":"https:\/\/www.delveinsight.com\/blog\/immune-thrombocytopenia-market","title":{"rendered":"R&D and Upcoming therapies Paving the Way for a Potential and Better Cure for Immune Thrombocytopenia"},"content":{"rendered":"\n

The Immune Thrombocytopenia market size in the 7MM was estimated to be approximately USD 2,527.72 million in 2017. The US accounts for the largest ITP Market size. <\/strong><\/p>\n\n\n\n

A disorder that results in an\nisolated low platelet count, Immune thrombocytopenia <\/strong>(ITP), is an\nautoimmune disorder that results in convincing body killing its platelets. It is\na disorder that affects the count of blood platelets rather than affecting their\nfunction and usually takes a self-limiting and benign course. <\/p>\n\n\n\n

Earlier, when the cause of the\ndisease was still mysterious, it was termed as idiopathic thrombocytopenic\npurpura. However, the case is different now. The advent of medical technologies\nand speedy treads traversed in an understanding of the haematology has\npresented a clear picture of the pathophysiology and etiology of the disease.\nFrom being hailed as idiopathic to Immune is in itself a proof of the increased\ndisease awareness. <\/p>\n\n\n\n

Immune thrombocytopenia Market<\/strong><\/p>\n\n\n\n

The recent discovery of the role of thrombopoietin (TPO) in managing the count of platelets has paved the way for better treatment options for Immune thrombocytopenia patients. The administration of TPO resulted in an increased quantity of the platelet count. Presently, the Immune thrombocytopenia Market consists of three FDA-approved TPO-RA therapies are Nplate<\/strong> (romiplostim), Promacta<\/strong> (eltrombopag), and Doptelet<\/strong> (avatrombopag). However, in Europe and Japan, only Nplate<\/strong> and Promacta<\/strong> are given recommendations from their respective regulatory authorities. <\/p>\n\n\n\n

However, DelveInsight estimates that after the expiration of the patents of the two drugs Promacta and Nplate in the US (in 2022), in Europe in 2025 for Promacta, whereas, Nplate had already lost the patent rights last year, Doptelet is anticipated to emerge as the major product occupying Immune thrombocytopenia market share. Thus, till 2022 Doptelet will continue to compete with both the drugs – Promacta and Nplate – and after the patent expiry, Doptelet will not have any competitor in the market. After the expiration, the Immune thrombocytopenia market is likely to experience an influx of the biologics and generics of Nplate and Promacta, hence a trend resulting in a declined value of ITP Market. <\/p>\n\n\n\n

In a similar line of TPO-RA therapies, most treatment options available in the Immune thrombocytopenia market focus on increasing the platelet count and dampening of the destruction body causes to its own platelets. Besides TPO-RAs, various drugs like, Takecab<\/strong>, and Nexium<\/strong> capsules have received approval in Japan and are indicated for the eradication of Helicobacter pylori<\/em> in patients afflicted with the Immune thrombocytopenia. <\/p>\n\n\n\n

Interestingly, management of Immune\nthrombocytopenia varies widely, and current international guidelines recommend\nseveral first- and second-line options, including some medicinal products that\nhave not been approved in the EU for this particular condition. First-line\ntreatment options include corticosteroids<\/strong>, intravenous immunoglobulin<\/strong>\n(IVIg) and intravenous anti-D immunoglobulin<\/strong> (the latter only for\nnon-splenectomized Rhesus-D positive patients). Patients who fail to respond or\nwho relapse face the options of treatment with second-line drug therapy or\nsplenectomy, but there is no clear evidence to support the best approach. <\/p>\n\n\n\n

Second-line drug therapies include high dose dexamethasone<\/strong> or methylprednisolone<\/strong>, high-dose IVIg or anti-D Ig<\/strong>, vinca alkaloids<\/strong> and danazol<\/strong>; immunosuppressants such as cyclophosphamide<\/strong>, azathioprine<\/strong>, and cyclosporine<\/strong> or mycophenolate mofetil<\/strong>, and the anti-CD-20 monoclonal antibody rituximab.<\/strong><\/p>\n\n\n\n

Furthermore, prospective trials, by several pharma companies including Octapharma USA, Amgen, CSL Behring, Dova Pharmaceuticals, Rigel Pharmaceuticals, Zenyaku Kogyo\/Biogen Idec, Novartis, Bio Products Laboratory’s, Takeda Pharmaceutical Company Limited, AstraZeneca, Biotest, GC Pharma, SK Plasma, Jiangsu HengRui Medicine, Argenx, Genosco (a US-based subsidiary of Korean bio company Oscotec), Kezar Life Sciences, UCB Biopharma, Bristol-Myers Squibb, Principia Biopharma, and Protalex, are underway that may be able to enhance the approach and improve overall outcomes in ITP patients. There are many pipeline therapies under development in the Immune thrombocytopenia market<\/a><\/strong>; and with the expected launch of upcoming therapies, BT595 (Biotest) in 2021; UCB7665 (UCB Biopharma) in and ARGX-113 (Argenx BVBA) in 2023, the market will experience significant growth.<\/p>\n\n\n\n

However, it demands closer monitoring to check for the risk of relapses and potential side effects due to the administration of a combination of therapies. Moreover, it is imperative to focus on essential research that helps in distinguish between patients who would benefit from more intensive therapy, or the ability to manage persistent or chronic ITP or identification of markers that would help in prescribing the regiment that would mot benefit. Conclusively, emerging Immune thrombocytopenia therapies<\/a> in the horizon are anticipated to bring a revolutionary change in the Immune thrombocytopenia market by 2030.  <\/p>\n","protected":false},"excerpt":{"rendered":"

The Immune Thrombocytopenia market size in the 7MM was estimated to be approximately USD 2,527.72 million in 2017. The US accounts for the largest ITP Market size. A disorder that results in an isolated low platelet count, Immune thrombocytopenia (ITP), is an autoimmune disorder that results in convincing body killing its platelets. It is a 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href=\"https:\/\/www.delveinsight.com\/blog\/articles\/\" class=\"advgb-post-tax-term\">Articles<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Facts and Figures<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Articles<\/span>","<span class=\"advgb-post-tax-term\">Facts and Figures<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">ARGX-113 Argenx BVBA<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Biotest<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">BT595<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Emerging Immune Thrombocytopenia Therapies<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Immune Thrombocytopenia<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Immune Thrombocytopenia Market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Immune Thrombocytopenia Market Size<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Immune Thrombocytopenia Pipeline<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">Immune Thrombocytopenia Treatment Market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">ITP Market<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">nplate<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">promacta<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">UCB Biopharma<\/a>","<a href=\"https:\/\/www.delveinsight.com\/blog\/facts-and-figures\/\" class=\"advgb-post-tax-term\">UCB7665<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">ARGX-113 Argenx BVBA<\/span>","<span class=\"advgb-post-tax-term\">Biotest<\/span>","<span class=\"advgb-post-tax-term\">BT595<\/span>","<span class=\"advgb-post-tax-term\">Emerging Immune Thrombocytopenia Therapies<\/span>","<span class=\"advgb-post-tax-term\">Immune Thrombocytopenia<\/span>","<span class=\"advgb-post-tax-term\">Immune Thrombocytopenia Market<\/span>","<span class=\"advgb-post-tax-term\">Immune Thrombocytopenia Market Size<\/span>","<span class=\"advgb-post-tax-term\">Immune Thrombocytopenia Pipeline<\/span>","<span class=\"advgb-post-tax-term\">Immune Thrombocytopenia Treatment Market<\/span>","<span class=\"advgb-post-tax-term\">ITP Market<\/span>","<span class=\"advgb-post-tax-term\">nplate<\/span>","<span class=\"advgb-post-tax-term\">promacta<\/span>","<span class=\"advgb-post-tax-term\">UCB Biopharma<\/span>","<span class=\"advgb-post-tax-term\">UCB7665<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 6 years ago","modified":"Updated 12 months ago"},"absolute_dates":{"created":"Posted on May 25, 2020","modified":"Updated on May 8, 2025"},"absolute_dates_time":{"created":"Posted on May 25, 2020 6:11 pm","modified":"Updated on May 8, 2025 1:56 pm"},"featured_img_caption":"Immune Thrombocytopenia 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