DelveInsight’s, “Advanced Renal Cell Carcinoma - Pipeline Insight, 2022,” report provides comprehensive insights about 40+ companies and 40+ pipeline drugs in Advanced Renal Cell Carcinoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Renal cell carcinoma is the most common type of kidney cancer. It usually starts as a tumor in one of your kidneys. And like other cancers, it can spread to other parts of your body. That’s when doctors call it metastatic. As the tumor grows, it spreads into fat or major blood vessels around the kidney. It may also creep into the adrenal gland, which sits right on top of the organ. Kidney cancer most often spreads to the lungs and bones, but it can also go to the brain, liver, ovaries, and testicles. The process used to find out if cancer has spread within the kidney or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment. The following tests and procedures may be used in the staging process: CT scan; MRI (magnetic resonance imaging); Chest x-ray; and bone scan. Different types of treatments are available for patients with renal cell cancer. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials.
"Advanced Renal Cell Carcinoma - Pipeline Insight, 2022" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Advanced Renal Cell Carcinoma pipeline landscape is provided which includes the disease overview and Advanced Renal Cell Carcinoma treatment guidelines. The assessment part of the report embraces, in depth Advanced Renal Cell Carcinoma commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Advanced Renal Cell Carcinoma collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
The companies and academics are working to assess challenges and seek opportunities that could influence Advanced Renal Cell Carcinoma R&D. The therapies under development are focused on novel approaches to treat/improve Advanced Renal Cell Carcinoma.
Advanced Renal Cell Carcinoma Emerging Drugs Chapters
This segment of the Advanced Renal Cell Carcinoma report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Advanced Renal Cell Carcinoma Emerging Drugs
Atezolizumab: Roche
Atezolizumab is a humanized monoclonal antibody immune checkpoint inhibitor that selectively binds to PD-L1 to stop the interaction between PD-1 and B7. 1 (ie, CD80 receptors). The antibody still allows interaction between PD-L2 and PD-1. Currently, it is in Phase III stage of clinical trial evaluation to treat advanced Renal Cell Carcinoma.
Bempegaldesleukin (NKTR-214): Nektar Therapeutics
Bempegaldesleukin is a CD122-preferential IL-2 pathway agonist designed to stimulate the patient's own immune system to fight cancer. Bempegaldesleukin is designed to grow specific cancer-killing T cells and natural killer (NK) cell populations in the body which fight cancer, which are known as endogenous tumor-infiltrating lymphocytes (TILs). Bempegaldesleukin stimulates these cancer-killing immune cells in the body by targeting CD122 specific receptors found on the surface of these immune cells, known as CD8+ effector T cells and NK cells. CD122, which is also known as the Interleukin-2 receptor beta subunit, is a key signaling receptor that is known to increase proliferation of these effector T cells. In clinical and preclinical studies, treatment with bempegaldesleukin resulted in expansion of these cells and mobilization into the tumor micro-environment. Bempegaldesleukin has an antibody-like dosing regimen similar to the existing checkpoint inhibitor class of approved medicines.
Further product details are provided in the report……..
This segment of the report provides insights about the different Advanced Renal Cell Carcinoma drugs segregated based on following parameters that define the scope of the report, such as:
There are approx. 40+ key companies which are developing the therapies for Advanced Renal Cell Carcinoma. The companies which have their Advanced Renal Cell Carcinoma drug candidates in the most advanced stage, i.e. phase III include, Roche.
DelveInsight’s report covers around 40+ products under different phases of clinical development like
Advanced Renal Cell Carcinoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Products have been categorized under various Molecule types such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Advanced Renal Cell Carcinoma therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Advanced Renal Cell Carcinoma drugs.
Current Treatment Scenario and Emerging Therapies:
Introduction
Executive Summary
Advanced Renal Cell Carcinoma: Overview
Pipeline Therapeutics
Therapeutic Assessment
Advanced Renal Cell Carcinoma – DelveInsight’s Analytical Perspective
Late Stage Products (Phase III)
Atezolizumab: Roche
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
Guadecitabine: Astex Pharmaceuticals
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
MEDI5752: MedImmune
Drug profiles in the detailed report…..
Inactive Products
Advanced Renal Cell Carcinoma Key Companies
Advanced Renal Cell Carcinoma Key Products
Advanced Renal Cell Carcinoma- Unmet Needs
Advanced Renal Cell Carcinoma- Market Drivers and Barriers
Advanced Renal Cell Carcinoma- Future Perspectives and Conclusion
Advanced Renal Cell Carcinoma Analyst Views
Advanced Renal Cell Carcinoma Key Companies
Appendix
List of Table
Table 1: Total Products for Advanced Renal Cell Carcinoma
Table 2: Late Stage Products
Table 3: Mid Stage Products
Table 4: Early Stage Products
Table 5: Pre-clinical & Discovery Stage Products
Table 6: Assessment by Product Type
Table 7: Assessment by Stage and Product Type
Table 8: Assessment by Route of Administration
Table 9: Assessment by Stage and Route of Administration
Table 10: Assessment by Molecule Type
Table 11: Assessment by Stage and Molecule Type
Table 12: Inactive Products
List of Figures
Figure 1: Total Products for Advanced Renal Cell Carcinoma
Figure 2: Late Stage Products
Figure 3: Mid Stage Products
Figure 4: Early Stage Products
Figure 5: Preclinical and Discovery Stage Products
Figure 6: Assessment by Product Type
Figure 7: Assessment by Stage and Product Type
Figure 8: Assessment by Route of Administration
Figure 9: Assessment by Stage and Route of Administration
Figure 10: Assessment by Molecule Type
Figure 11: Assessment by Stage and Molecule Type
Figure 12: Inactive Products
• Roche
• Nektar Therapeutic
• MedImmune LLC
• CoImmune
• X4 Pharmaceuticals
• Daiichi Sankyo, Inc.
• Eli Lilly and Company
• Jiangsu HengRui Medicine Co., Ltd.
• Allogene Therapeutics
• Apexigen, Inc.
• Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
• Aravive, Inc.
• Arrowhead Pharmaceuticals
• Merck
• Apollomics
• Astex Pharmaceuticals
• Peloton Therapeutics, Inc.
• Infinity Pharmaceuticals
• Surface Oncology
• AO GENERIUM
• CRISPR Therapeutics AG
