Ankylosing Spondylitis Bekhterevs Disease Pipeline Insight

DelveInsight’s, “Ankylosing Spondylitis (Bekhterev's Disease)– Pipeline Insight, 2021,” report provides comprehensive insights about 40+ companies and 40+ pipeline drugs in Ankylosing Spondylitis (Bekhterev's Disease) pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. 

Geography Covered

  • Global coverage

Ankylosing Spondylitis (Bekhterev's Disease) Understanding

Ankylosing Spondylitis (Bekhterev's Disease): Overview

Ankylosing Spondylitis (Bekhterev's Disease) (AS) is a form of arthritis that primarily affects the spine. It causes severe inflammation of the spinal joints (Vertebrae) that can lead to chronic pain and discomfort. Ankylosing Spondylitis (Bekhterev's Disease) also cause pain, inflammation in other parts of the body such as the shoulders, hips, ribs , heels and small joints of the hands and feet. In some cases, the eyes are also involved (known as iritis or uveitis). In more advanced cases, these inflammation can lead to new bone formation in the spine, causing sections of spine top fuse in fixed, immobile position. The hallmark feature of Ankylosing Spondylitis (Bekhterev's Disease) is the involvement of sacroiliac (SI) joints during the progression of disease. Ankylosing Spondylitis (Bekhterev's Disease) (AS) symptoms occurs at any age, but they start occurring at the age of 45. It also affect children, called juvenile Ankylosing Spondylitis (Bekhterev's Disease), and more commonly occur in boys than in girls.


"Ankylosing Spondylitis (Bekhterev's Disease)- Pipeline Insight, 2021" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Ankylosing Spondylitis (Bekhterev's Disease) pipeline landscape is provided which includes the disease overview and Ankylosing Spondylitis (Bekhterev's Disease) treatment guidelines. The assessment part of the report embraces, in depth Ankylosing Spondylitis (Bekhterev's Disease) commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Ankylosing Spondylitis (Bekhterev's Disease) collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Ankylosing Spondylitis (Bekhterev's Disease) R&D. The therapies under development are focused on novel approaches to treat/improve Ankylosing Spondylitis (Bekhterev's Disease).

Ankylosing Spondylitis (Bekhterev's Disease) Emerging Drugs Chapters

This segment of the Ankylosing Spondylitis (Bekhterev's Disease) report encloses its detailed analysis of various drugs in different stages of clinical development, including Phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.


Ankylosing Spondylitis (Bekhterev's Disease) Emerging Drugs


Tofacitinib: Pfizer

Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. By inhibiting JAKs, tofacitinib prevents the phosphorylation and activation of STATs. It is in Preregistration Phase.


Bimekizumab: UCB Biopharma

Bimekizumab is an investigational humanized monoclonal IgG1 antibody that selectively inhibits both IL-17A and IL-17F. Bimekizumab binds to and neutralizes IL-17A and IL-17F, preventing their interactions with the IL-17 receptors expressed on keratinocytes, fibroblast-like synoviocytes, endothelial cells, chondrocytes and osteoblasts. It is in Phase III of clinical trial.

Further product details are provided in the report……..

Ankylosing Spondylitis (Bekhterev's Disease): Therapeutic Assessment

This segment of the report provides insights about the different Ankylosing Spondylitis (Bekhterev's Disease) drugs segregated based on following parameters that define the scope of the report, such as:

  • Major Players in Ankylosing Spondylitis (Bekhterev's Disease)

There are approx. 40+ key companies which are developing the therapies for Ankylosing Spondylitis (Bekhterev's Disease). The companies which have their Ankylosing Spondylitis (Bekhterev's Disease) drug candidates in the most advanced stage, i.e. Preregistration include, Pfizer.

Phases

DelveInsight’s report covers around 40+ products under different phases of clinical development like

  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration


Ankylosing Spondylitis (Bekhterev's Disease) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral
  • Intravenous
  • Subcutaneous
  • Intramuscular
  • Topical.
  • Molecule Type


Products have been categorized under various Molecule types such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Ankylosing Spondylitis (Bekhterev's Disease): Pipeline Development Activities

The report provides insights into different therapeutic candidates in Phase III, II, I, preclinical and discovery stage. It also analyses Ankylosing Spondylitis (Bekhterev's Disease) therapeutic drugs key players involved in developing key drugs.


Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Ankylosing Spondylitis (Bekhterev's Disease) drugs.

Ankylosing Spondylitis (Bekhterev's Disease) Report Insights

  • Ankylosing Spondylitis (Bekhterev's Disease) Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Ankylosing Spondylitis (Bekhterev's Disease) Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

  • How many companies are developing Ankylosing Spondylitis (Bekhterev's Disease) drugs?
  • How many Ankylosing Spondylitis (Bekhterev's Disease) drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Ankylosing Spondylitis (Bekhterev's Disease)?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Ankylosing Spondylitis (Bekhterev's Disease) therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Ankylosing Spondylitis (Bekhterev's Disease) and their status?
  • What are the key designations that have been granted to the emerging drugs?

Introduction

Executive Summary

Ankylosing Spondylitis (Bekhterev's Disease): Overview

  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management

Pipeline Therapeutics

  • Comparative Analysis

Therapeutic Assessment

  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type

Ankylosing Spondylitis (Bekhterev's Disease)– DelveInsight’s Analytical Perspective

In-depth Commercial Assessment

  • Ankylosing Spondylitis (Bekhterev's Disease)companies’ collaborations, Licensing, Acquisition -Deal Value Trends

Ankylosing Spondylitis (Bekhterev's Disease) Collaboration Deals

  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis

Late Stage Products (Registered/Launch)

  • Comparative Analysis

MSB11022: Fresenius Kabi

  • Product Description
  • Research and Development
  • Product Development Activities

Late Stage Products (Preregistration)

  • Comparative Analysis

Tofacitinib: Pfizer

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Late Stage Products (Phase III)

  • Comparative Analysis

Bimekizumab: UCB Biopharma

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Mid Stage Products (Phase II/III)

  • Comparative Analysis

Tildrakizumab: Sun Pharma Global

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Mid Stage Products (Phase II)

  • Comparative Analysis

Namilumab: Izana Bioscience

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Early Stage Products (Phase I)

  • Comparative Analysis

KIN-1901: Kinevant Sciences

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Preclinical Stage Products

  • Comparative Analysis

Xcimzane: Xbrane Biopharma

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Discovery Stage Products

  • Comparative Analysis

DNA-encoded library (DEL) technology: Dice molecules

  • Product Description
  • Research and Development
  • Product Development Activities

Inactive Products

  • Comparative Analysis

Ankylosing Spondylitis (Bekhterev's Disease) Key Companies

Ankylosing Spondylitis (Bekhterev's Disease) Key Products

Ankylosing Spondylitis (Bekhterev's Disease)- Unmet Needs

Ankylosing Spondylitis (Bekhterev's Disease)- Market Drivers and Barriers

Ankylosing Spondylitis (Bekhterev's Disease)- Future Perspectives and Conclusion

Ankylosing Spondylitis (Bekhterev's Disease) Analyst Views

Ankylosing Spondylitis (Bekhterev's Disease) Key Companies

Appendix

List of Table

Table 1: Total Products for Ankylosing Spondylitis (Bekhterev's Disease)

Table 2: Late Stage Products

Table 3: Mid Stage Products

Table 4: Early Stage Products

Table 5: Pre-clinical & Discovery Stage Products

Table 6: Assessment by Product Type

Table 7: Assessment by Stage and Product Type

Table 8: Assessment by Route of Administration

Table 9: Assessment by Stage and Route of Administration

Table 10: Assessment by Molecule Type

Table 11: Assessment by Stage and Molecule Type

Table 12: Inactive Products

List of Figures

Figure 1: Total Products for Ankylosing Spondylitis (Bekhterev's Disease)

Figure 2: Late Stage Products                               

Figure 3: Mid Stage Products

Figure 4: Early Stage Products

Figure 5: Preclinical and Discovery Stage Products

Figure 6: Assessment by Product Type

Figure 7: Assessment by Stage and Product Type

Figure 8: Assessment by Route of Administration

Figure 9: Assessment by Stage and Route of Administration

Figure 10: Assessment by Molecule Type

Figure 11: Assessment by Stage and Molecule Type

Figure 12: Inactive Products    

• Fresenius Kabi

• Shanghai Henlius Biotech

• Pfizer

• Fujifilm Kyowa Kirin Biologics

• Hetero Biopharma

• Bio-Thera Solutions

• Amgen

• CinnaGen

• Zydus cadilla

• Cadila Pharmaceuticals

• Sandoz

• Innovent Biologics

• Fresenius Kabi

• Torrent Pharmaceuticals

• Cipla

• Emcure Pharmaceuticals

• Biogen

• Boehringer Ingelheim

• Zhejiang Hisun Pharmaceuticals

• Biocad

• Biocad

• AbbVie

• Mycenax Biotech

• Celltrion

• UCB Biopharma

• Gilead Sciences

• Amgen

• Sun Pharma Global

• Jiangsu HengRui Medicine Co., Ltd.

• Izana Bioscience

• Suzhou Zelgen Biopharmaceuticals

• Iltoo Pharma

• Kinevant Sciences

• Qyuns Therapeutics

• Akeso Biopharma

• Nimbus Therapeutics

• Enzene Biosciences

• Xbrane Biopharma

• Dice molecules

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