Arteriovenous Fistula Av Pipeline Insight

DelveInsight’s, “Arteriovenous fistula (AV) – Pipeline Insights, 2021,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in Arteriovenous fistula (AV) pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. 

Geography Covered

  • Global coverage

Arteriovenous fistula (AV) Understanding

Arteriovenous fistula (AV): Overview

Arteriovenous fistula (AV) is an abnormal connection between an artery and a vein, in which blood flows directly from an artery into a vein, bypassing some capillaries. Small arteriovenous fistulas in your legs, arms, lungs, kidneys or brain are not much complicated while a large untreated arteriovenous fistula can lead to serious complications. An AV can develop anywhere in the body, though typically occur in the head, neck, spine, and liver.They can be caused from congenital defects or acquired as a results of cardiac catheterization complication, injuries that pierce the skin, and genetic conditions.


Arteriovenous fistulas are often surgically created by vascular surgeon for use in dialysis in people with severe kidney disease.

Symptoms

Small arteriovenous fistulas often won't have any signs or symptoms and are usually don't need specialized treatment. Large arteriovenous fistulas may cause signs and symptoms. The symptoms of large Arteriovenous fistula (AV) include:

  • Heartburn or gastroesophageal reflux (backup of stomach contents into the esophagus)
  • Purplish, bulging veins that you can see through your skin, similar to varicose veins
  • Swelling in the arms or legs
  • Decreased blood pressure
  • Fatigue
  • Heart failure
  • bluish tinge on the skin
  • Clubbing of fingers
  • Coughing up blood
  • An arteriovenous fistula in your gastrointestinal tract can cause bleeding in digestive tract

Diagnosis

A diagnosis of Arteriovenous fistula (AV) is made based upon a thorough clinical evaluation, a detailed patient history, and a variety of specialized tests. Tests to diagnose an Arteriovenous fistula can include: Duplex ultrasound, Computerized tomography (CT) angiogram, and Magnetic resonance angiography (MRA).

Treatment

For small arteriovenous fistula a close monitoring by a doctor is sufficient, these fistula may close by themselves without treatment. Treatment options for large fistula includes endovascular embolization, ultrasound-guided compression, microsurgery, or stereotactic radiosurgery.

Arteriovenous fistula (AV) Emerging Drugs Chapters

This segment of the Arteriovenous fistula (AV) report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Arteriovenous fistula (AV) Emerging Drugs

  • REM-001: Kintara Therapeutics

REM-001 is a photosensitizer agent. REM-001, a photodynamic therapy (PDT) that consists of a drug, a laser light source and a light delivery device.


Kintara Therapeutics has received Small Business Technology Transfer grant to study REM-001 for the prevention of arteriovenous fistula maturation failure (AFMF).

Further product details are provided in the report……..

Arteriovenous fistula (AV): Therapeutic Assessment

This segment of the report provides insights about the different Arteriovenous fistula (AV) drugs segregated based on following parameters that define the scope of the report, such as:


  • Major Players in Arteriovenous fistula (AV)

There are approx. 5+ key companies which are developing the therapies for Arteriovenous fistula (AV). The companies which have their Arteriovenous fistula (AV) drug candidates in the most advanced stage, i.e. phase II include, Enceladus Pharmaceuticals.


  • Phases

DelveInsight’s report covers around 5+ products under different phases of clinical development like

  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration


Arteriovenous fistula (AV) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral
  • Parenteral
  • intravitreal
  • Subretinal
  • Topical.
  • Molecule Type


Products have been categorized under various Molecule types such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.


Arteriovenous fistula (AV): Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Arteriovenous fistula (AV) therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Arteriovenous fistula (AV) drugs.

Report Highlights

  • The companies and academics are working to assess challenges and seek opportunities that could influence Arteriovenous fistula (AV) R&D. The therapies under development are focused on novel approaches to treat/improve Arteriovenous fistula (AV).


Arteriovenous fistula (AV) Report Insights

  • Arteriovenous fistula (AV) Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs


Arteriovenous fistula (AV) Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

  • How many companies are developing Arteriovenous fistula (AV) drugs?
  • How many Arteriovenous fistula (AV) drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Arteriovenous fistula (AV)?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Arteriovenous fistula (AV) therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Arteriovenous fistula (AV) and their status?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Kintara Therapeutics
  • Enceladus Pharmaceuticals
  • Symic Bio
  • Vascular Therapies
  • C. R. Bard

Key Products

  • Rostaporfin
  • Liposome encapsulated prednisolone
  • Proteoglycan-like compounds
  • Sirolimus-eluting implant
  • Lutonix DCB

 

Introduction

Executive Summary

Arteriovenous fistula (AV): Overview

• Causes

• Mechanism of Action

• Signs and Symptoms

• Diagnosis

• Disease Management

Pipeline Therapeutics

• Comparative Analysis

Therapeutic Assessment

• Assessment by Product Type

• Assessment by Stage and Product Type

• Assessment by Route of Administration

• Assessment by Stage and Route of Administration

• Assessment by Molecule Type

• Assessment by Stage and Molecule Type

Arteriovenous fistula (AV) – DelveInsight’s Analytical Perspective

In-depth Commercial Assessment

• Arteriovenous fistula (AV) companies’ collaborations, Licensing, Acquisition -Deal Value Trends

Arteriovenous fistula (AV) Collaboration Deals

• Company-Company Collaborations (Licensing / Partnering) Analysis

• Company-University Collaborations (Licensing / Partnering) Analysis

Mid Stage Products (Phase II)

• Comparative Analysis

Liposome encapsulated prednisolone: Enceladus Pharmaceuticals

• Product Description

• Research and Development

• Product Development Activities

Drug profiles in the detailed report…..

Pre-clinical and Discovery Stage Products

• Comparative Analysis

Rostaporfin - Kintara Therapeutics

• Product Description

• Research and Development

• Product Development Activities

Drug profiles in the detailed report…..

Inactive Products

• Comparative Analysis

Arteriovenous fistula (AV) Key Companies

Arteriovenous fistula (AV) Key Products

Arteriovenous fistula (AV)- Unmet Needs

Arteriovenous fistula (AV)- Market Drivers and Barriers

Arteriovenous fistula (AV)- Future Perspectives and Conclusion

Arteriovenous fistula (AV) Analyst Views

Arteriovenous fistula (AV) Key Companies

Appendix

List of Table

 Table 1 Total Products for Arteriovenous fistula (AV)

Table 2 Late Stage Products

Table 3 Mid Stage Products

Table 4 Early Stage Products

Table 5 Pre-clinical & Discovery Stage Products

Table 6 Assessment by Product Type

Table 7 Assessment by Stage and Product Type

Table 8 Assessment by Route of Administration

Table 9 Assessment by Stage and Route of Administration

Table 10 Assessment by Molecule Type

Table 11 Assessment by Stage and Molecule Type

Table 12 Inactive Products

List of Figures

Figure 1 Total Products for Arteriovenous fistula (AV)

Figure 2 Late Stage Products

Figure 3 Mid Stage Products

Figure 4 Early Stage Products

Figure 5 Preclinical and Discovery Stage Products

Figure 6 Assessment by Product Type

Figure 7 Assessment by Stage and Product Type

Figure 8 Assessment by Route of Administration

Figure 9 Assessment by Stage and Route of Administration

Figure 10 Assessment by Molecule Type

Figure 11 Assessment by Stage and Molecule Type

Figure 12 Inactive Products

• Kintara Therapeutics

• Enceladus Pharmaceuticals

• Symic Bio

• Vascular Therapies

• C. R. Bard

  • Tags:
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  • Arteriovenous fistula drugs
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  • Arteriovenous fistula

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