Bronchopulmonary Dysplasia Pipeline Insight

DelveInsight’s, “Bronchopulmonary Dysplasia - Pipeline Insight, 2022,” report provides comprehensive insights about 12+ companies and 12+ pipeline drugs in Bronchopulmonary Dysplasia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. 

Geography Covered

  • Global coverage

Bronchopulmonary Dysplasia Understanding

Bronchopulmonary Dysplasia: Overview

Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease that most often occurs in low-weight or premature infants who have received supplemental oxygen or have spent long periods of time on a breathing machine (mechanical ventilation), such as infants who have acute respiratory distress syndrome. BPD can also occur in older infants who experience abnormal lung development or some infants that have had an infection before birth (antenatal infection) or placental abnormalities (such as preeclampsia). Antenatal steroid treatment prior to preterm birth and early treatment with surfactant have reduced the need for high levels of respiratory support after birth. Some infants who develop BPD have a condition called respiratory distress syndrome (RSD), which is a breathing disorder that affects some premature infants immediately after birth. It is characterized by rapid, shallow breathing and leads to the need for oxygen and respiratory support in the first days of life. BPD is caused by damage to the delicate tissue of the lungs. This damage is most often occurs in infants who have required extended treatment with supplemental oxygen or breathing assistance with a machine (mechanical ventilation) such as infants who are born prematurely and have acute respiratory distress syndrome.

 

"Bronchopulmonary Dysplasia - Pipeline Insight, 2022" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Bronchopulmonary Dysplasia pipeline landscape is provided which includes the disease overview and Bronchopulmonary Dysplasia treatment guidelines. The assessment part of the report embraces, in depth Bronchopulmonary Dysplasia commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Bronchopulmonary Dysplasia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

  • A better understanding of disease pathogenesis contributing to the development of novel therapeutics for Bronchopulmonary Dysplasia.   
  • In the coming years, the Bronchopulmonary Dysplasia market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
  • The companies and academics that are working to assess challenges and seek opportunities that could influence Bronchopulmonary Dysplasia R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition.
  • A detailed portfolio of major pharma players who are involved in fueling the Bronchopulmonary Dysplasia treatment market. Several potential therapies for Bronchopulmonary Dysplasia are under investigation. With the expected launch of these emerging therapies, it is expected that there will be a significant impact on the Bronchopulmonary Dysplasia market size in the coming years. 
  • Our in-depth analysis of the pipeline assets (in early-stage, mid-stage and late stage of development for the treatment of Bronchopulmonary Dysplasia) includes therapeutic assessment and comparative analysis. This will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.

Bronchopulmonary Dysplasia Emerging Drugs Chapters

This segment of the Bronchopulmonary Dysplasia report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

 

Bronchopulmonary Dysplasia Emerging Drugs

 

PNEUMOSTEM: MEDIPOST Co., Ltd.

PNEUMOSTEM® an allogeneic umbilical cord blood-derived mesenchymal stem cell product, is currently under development for the preventive treatment of Bronchopulmonary Dysplasia (BPD) in premature infants. Currently, Phase 2 clinical trial is ongoing in Korea and PNEUMOSTEM® has been Orphan Drug designated by US FDA and EMA. Recently, US FDA granted a Fast Track Designation for PNEUMOSTEM®.

 

AT-100:Airway Therapeutics

AT-100 is a novel recombinant human protein rhSP-D, an engineered version of an endogenous protein that reduces inflammation and infection in the body while modulating the immune response to break the cycle of injury and inflammation. Airway is focused on advancing AT-100 for the prevention of BPD in very preterm born babies and as a therapeutic for seriously ill COVID-19 patients. AT-100’s anti-inflammatory and anti-infective properties also make it a potential treatment for other respiratory diseases such as influenza, respiratory syncytial virus (RSV) and inflammatory diseases outside the lung. The FDA and European Medicines Agency have granted AT-100 Orphan Drug Designation.

Further product details are provided in the report……..

Bronchopulmonary Dysplasia: Therapeutic Assessment

This segment of the report provides insights about the different Bronchopulmonary Dysplasia drugs segregated based on following parameters that define the scope of the report, such as:

 

Major Players in Bronchopulmonary Dysplasia

There are approx. 12+ key companies which are developing the therapies for Bronchopulmonary Dysplasia. The companies which have their Bronchopulmonary Dysplasia drug candidates in the most advanced stage, i.e. phase III include, AstraZeneca.

 

Phases

DelveInsight’s report covers around 12+ products under different phases of clinical development like

  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates

 

Route of Administration

Bronchopulmonary Dysplasia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Inhalation
  • Inhalation/Intravenous/Oral
  • Intranasal
  • Intravenous
  • Intravenous/ Subcutaneous
  • NA
  • Oral
  • Oral/intranasal/subcutaneous
  • Parenteral
  • Subcutaneous

 

Molecule Type

Products have been categorized under various Molecule types such as

  • Antibody
  • Antisense oligonucleotides
  • Immunotherapy
  • Monoclonal antibody
  • Peptides
  • Protein
  • Recombinant protein
  • Small molecule
  • Stem Cell
  • Vaccine

 

Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Bronchopulmonary Dysplasia: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Bronchopulmonary Dysplasia therapeutic drugs key players involved in developing key drugs.

 

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Bronchopulmonary Dysplasia drugs.

Bronchopulmonary Dysplasia Report Insights

  • Bronchopulmonary Dysplasia Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Bronchopulmonary Dysplasia Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

  • How many companies are developing Bronchopulmonary Dysplasia drugs?
  • How many Bronchopulmonary Dysplasia drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Bronchopulmonary Dysplasia?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Bronchopulmonary Dysplasia therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Bronchopulmonary Dysplasia and their status?
  • What are the key designations that have been granted to the emerging drugs?

Introduction

Executive Summary

Bronchopulmonary Dysplasia: Overview

  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management

Pipeline Therapeutics

  • Comparative Analysis

Therapeutic Assessment

  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type

Bronchopulmonary Dysplasia – DelveInsight’s Analytical Perspective

Late Stage Products (Phase III)

  • Comparative Analysis

Drug name: Company name

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Mid Stage Products (Phase II)

  • Comparative Analysis

PNEUMOSTEM: MEDIPOST Co., Ltd.

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Early Stage Products (Phase I)

  • Comparative Analysis

AT-100: Airway Therapeutics

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Preclinical and Discovery Stage Products

  • Comparative Analysis

AVR 48: AyuVis Research

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Inactive Products

  • Comparative Analysis

Bronchopulmonary Dysplasia Key Companies

Bronchopulmonary Dysplasia Key Products

Bronchopulmonary Dysplasia- Unmet Needs

Bronchopulmonary Dysplasia- Market Drivers and Barriers

Bronchopulmonary Dysplasia- Future Perspectives and Conclusion

Bronchopulmonary Dysplasia Analyst Views

Bronchopulmonary Dysplasia Key Companies

Appendix

List of Table

Table 1: Total Products for Bronchopulmonary Dysplasia

Table 2: Late Stage Products

Table 3: Mid Stage Products

Table 4: Early Stage Products

Table 5: Pre-clinical & Discovery Stage Products

Table 6: Assessment by Product Type

Table 7: Assessment by Stage and Product Type

Table 8: Assessment by Route of Administration

Table 9: Assessment by Stage and Route of Administration

Table 10: Assessment by Molecule Type

Table 11: Assessment by Stage and Molecule Type                                              

Table 12: Inactive Products

List of Figures

Figure 1: Total Products for Bronchopulmonary Dysplasia

Figure 2: Late Stage Products                             

Figure 3: Mid Stage Products

Figure 4: Early Stage Products

Figure 5: Preclinical and Discovery Stage Products

Figure 6: Assessment by Product Type                                                                       

Figure 7: Assessment by Stage and Product Type

Figure 8: Assessment by Route of Administration

Figure 9: Assessment by Stage and Route of Administration

Figure 10: Assessment by Molecule Type

Figure 11: Assessment by Stage and Molecule Type

Figure 12: Inactive Products

• MEDIPOST Co., Ltd.
• Airway Therapeutics
• Oak Hill Bio Ltd
• Meridigen Biotech
• AyuVis Research
• CHIESI Farmaceutici S.p.A.
• Velvio
• Orphanix
• Alveolus Bio Inc
• Advent Therapeutics
• Trimunocor
• The Cell Factory BVBA
• Windtree Therapeutics

 

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