Diabetic Foot Ulcers Dfus Epidemiology Forecast Insight
DelveInsight’s ‘Diabetic Foot Ulcer (DFU) - Epidemiology Forecast to 2030’ report delivers an in-depth understanding of the disease, historical and forecasted DFU epidemiology in the 7MM, i.e., the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
Geographies Covered
- The United States
- EU5 (Germany, France, Italy, Spain, and the United Kingdom)
- Japan
Study Period: 2018–2030
Diabetic Foot Ulcer (DFU) Understanding
Diabetic Foot Ulcer Overview
Diabetic foot ulcer (DFU) is an open sore or wound in patients with diabetes; they occur in type 1 and type 2 diabetes mellitus. The average duration of diabetes before ulceration is >10 years. The wound is commonly located on the bottom of the foot. A DFU is caused by neuropathic (nerve) and vascular (blood vessel) complications of diabetes. Nerve damage due to diabetes causes altered or complete loss of feeling in the foot and/or leg, known as peripheral neuropathy.
DFU may result in an infection or other ulcer-related complications that can lead to hospitalization. Foot ulcers are a common complication of poorly controlled diabetes. Diabetic foot ulcers form when the lower layers are exposed after the skin tissues break down. When blood sugar levels are high or regularly fluctuate, skin that would usually heal may not properly repair itself because of nerve damage. These ulcers are most common under the big toes and the balls of feet and can affect the feet down to the bones.
DFUs are complex, chronic wounds, which have a major long-term impact on the morbidity, mortality, and quality of patients’ lives. Individuals who develop a DFU are at greater risk of premature death, myocardial infarction, and fatal stroke than those without a history of DFU. Unlike other chronic wounds, the development and progression of a DFU are often complicated by wide-ranging diabetic changes, such as neuropathy and vascular disease. In most DFU patients, peripheral neuropathy and peripheral arterial disease (PAD) (or both) play a central role. Therefore, DFU can be commonly classified into three types i.e. Neuropathic, Ischemic, and Neuro-ischemic.
Diabetic Foot Ulcer (DFU) Diagnosis
The most significant risk factors for foot ulceration are diabetic neuropathy, peripheral arterial disease, and consequent traumas of the foot. Other risk factors include tobacco use, alcohol consumption, poorly fitted or poor quality shoes, poor hygiene, improper trimming of toenails, poor glycemic control, and previous foot ulcerations. Diagnosis of DFU includes the doctor investigating the patient’s medical history for signs of any previous complication or medical condition. Other than this diagnosis of DFU requires a physical examination for checking the current condition, a few blood tests for screening any infection, and a metabolic profile to measure glucose levels. Radiological imaging tests, such as CT scan, MRI, Arteriography, etc. may also be used to gather detailed information about the DFU.
Epidemiology Perspective by DelveInsight
The DFU epidemiology division provides insights about historical and current DFU patient pool and forecasted trends for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Key Findings
In the year 2020, the total prevalent case of DFU was 5,994,978 cases in the 7MM which are expected to grow during the study period, i.e., 2018–2030.
The disease epidemiology covered in the report provides historical as well as forecasted DFU epidemiology [segmented as Total Prevalent Cases of DFU, Total Diagnosed Cases of DFU, Gender-specific cases of DFU, Age-specific Cases of DFU, DFU cases by severity/chronicity of wound, and Treated cases of DFU] in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2018 to 2030.
Country Wise- DFU Epidemiology
Estimates show that the highest cases of DFU in the 7MM were in the United States, followed by Italy, Germany, France, the United Kingdom, Spain, and Japan in 2020.
- In the United States, the total number of prevalent cases of DFU was 4,551,498 cases in the year 2020 which are expected to grow during the study period, i.e., 2018–2030.
- In the year 2020, the total prevalent cases of DFU were 1,274,933 cases in EU-5 which are expected to grow during the study period, i.e., 2018–2030.
- In Japan, the total number of prevalent cases of DFU was 168,547 cases in the year 2020 which are expected to grow during the study period, i.e., 2018–2030.
- In the 7MM, the total gender-specific prevalent cases of DFU were 2,149,948 for males and 1,374,864 for females in the year 2020.
- In the 7MM, the total age-specific prevalent cases of DFU were 506,498, 1,529,831, and 1,488,484 cases for the age group less than 18–44, 45–64, and ≥75 years, respectively in 2020.
Scope of the Report
- The DFU report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis, and treatment patterns.
- The DFU Report and Model provide an overview of the risk factors and global trends of DFU in the seven major markets (7MM: The United States, Germany, France, Italy, Spain, and the United Kingdom, and Japan)
- The report provides insight about the historical and forecasted patient pool of DFU in seven major markets covering the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
- The report helps to recognize the growth opportunities in the 7MM concerning the patient population.
- The report assesses the disease risk and burden and highlights the unmet needs of DFU.
- The report provides the segmentation of the DFU epidemiology by total prevalent cases in the 7MM.
- The report provides the segmentation of the DFU epidemiology by total diagnosed cases in the 7MM.
- The report provides the segmentation of the DFU epidemiology by gender-specific prevalent cases in the 7MM.
- The report provides the segmentation of the DFU epidemiology by age-specific prevalent cases in the 7MM.
- The report provides the segmentation of the DFU epidemiology by severity/chronicity of wound in the 7MM.
- The report provides the segmentation of the DFU epidemiology by treated cases in the 7MM.
Report Highlights
- 10-Year Forecast of DFU epidemiology
- 7MM Coverage
- Total Prevalent Cases of DFU
- Total Diagnosed Cases of DFU
- Gender-Specific Prevalent Cases of DFU
- Age-Specific Prevalent Cases of DFU
- Severity/chronicity of wound Cases of DFU
- Treated Cases of DFU
KOL-Views
We interview KOL’s and SME's opinion through primary research to fill the data gaps and validate our secondary research. The opinion helps to understand the total patient population and current treatment pattern. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the indications.
Key Questions Answered
- What will be the growth opportunities in the 7MM concerning the patient population of DFU?
- What are the key findings of the DFU epidemiology across the 7MM and which country will have the highest number of patients during the study period (2018–2030)?
- What would be the total number of patients of DFU across the 7MM during the study period (2018–2030)?
- Among the EU5 countries, which country will have the highest number of patients during the study period (2018–2030)?
- At what CAGR the patient population is expected to grow in the 7MM during the study period (2018–2030)?
- What are the various recent and upcoming events which are expected to improve the diagnosis of DFU?
Reasons to buy
The DFU Epidemiology report will allow the user to -
- Develop business strategies by understanding the trends shaping and driving the global DFU market
- Quantify patient populations in the global DFU market to improve product design, pricing, and launch plans
- Organize sales and marketing efforts by identifying the gender that presents the best opportunities for DFU therapeutics in each of the markets covered
- Understand the magnitude of DFU population by its severity
- The DFU epidemiology report and model were written and developed by Masters and Ph.D. level epidemiologists
- The DFU Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over an 10-year forecast period using reputable sources
Key Assessments
- Patient Segmentation
- Disease Risk and Burden
- Risk of disease by the segmentation
- Factors driving growth in a specific patient population
