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Diverticulitis Pipeline Insight

DelveInsight’s,“Diverticulitis – Pipeline Insights, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Diverticulitis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. 

Geography Covered

  • Global coverage

Diverticulitis Understanding

Diverticulitis: Overview

Diverticulitis is inflammation of one or more balloon-like sacs (diverticula). Diverticulitis usually affects the large intestine (colon). Diverticulitis occurs in people, when a diverticulum develops a small (sometimes microscopic) hole that allows bacteria from the intestines to be released. Diverticulitis is inflammation of one or more balloon-like sacs (diverticula). Infection may or may not develop.

Symptoms

The symptoms of Diverticulitis include:

  • Abdominal pain
  • Bloating
  • Fever
  • Inflammation can lead to bowel obstruction
  • Constipation

Diagnosis

The diagnosis includes clinical data, routine laboratory tests for inflammation, calprotectin in stool, coloscopy, ultrasound, CT and magnetic resonance.

Treatment

Antibiotics, dietary modification, and pain control have been the mainstays of treatment for patients with uncomplicated diverticulitis; surgical resection has been the cornerstone for treatment of complicated diverticulitis and recurrence. The basis for the treatment of symptomatic uncomplicated diverticular disease consists of drugs bringing symptomatic relief, fibre, probiotics, mesalazine and non-absorbable antibiotics, nonetheless the results of a number of studies are not fully convincing. The recommended treatment should be initiated with dietary fibre and probiotics, in the case of lasting problems add a non-absorbable antibiotic rifaximine with cyclic administration. Mild diverticulitis should essentially be treated by means of hydration and adjustments in the dietary regimen, antibiotics are not necessary when its course is uncomplicated and improvement is achieved, however the decision is individual and risk factors such as immunosuppression, diabetes, old age, pregnancy etc. Antibiotics are reserved for the treatment of severe or repeated diverticulitis, sepsis and complications. As prevention of further attacks, again probiotics, mesalazine and cyclically non-absorbable antibiotics are used, e,g. for a period of 10 days at monthly intervals.

Diverticulitis Emerging Drugs Chapters

This segment of the Diverticulitis report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Diverticulitis Emerging Drugs

  • Rifamycin: Salix Pharmaceuticals

Rifamycin is in Phase II trial of clinical study, which acts as DNA- directed RNA polymerase inhibitors and is being developed by Salix Pharmaceuticals.

Further product details are provided in the report……..

Diverticulitis: Therapeutic Assessment

This segment of the report provides insights about the different Diverticulitis drugs segregated based on following parameters that define the scope of the report, such as:


  • Major Players in Diverticulitis

There are approx. 10+ key companies which are developing the therapies for Diverticulitis. The companies which have their Diverticulitis drug candidates in the most advanced stage, i.e. phase II include, Salix Pharmaceuticals.


  • Phases

DelveInsight’s report covers around 10+ products under different phases of clinical development like

  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration


Diverticulitis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral
  • Parenteral
  • intravitreal
  • Subretinal
  • Topical.
  • Molecule Type


Products have been categorized under various Molecule types such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.


Diverticulitis: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Diverticulitis therapeutic drugs key players involved in developing key drugs.


Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Sturge- Weber Syndrome drugs.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Diverticulitis R&D. The therapies under development are focused on novel approaches to treat/improve Diverticulitis.

Diverticulitis Report Insights

  • Diverticulitis Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Diverticulitis Disease Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

  • How many companies are developing Diverticulitis drugs?
  • How many Diverticulitis drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Diverticulitis?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Diverticulitis therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Diverticulitis and their status?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Salix Pharmaceuticals
  • Emmaus Medical

Key Products

  • Rifamycin
  • Glutamine

 

Introduction

Executive Summary

Diverticulitis: Overview

• Causes

• Mechanism of Action

• Signs and Symptoms

• Diagnosis

• Disease Management

Pipeline Therapeutics

• Comparative Analysis

Therapeutic Assessment

• Assessment by Product Type

• Assessment by Stage and Product Type

• Assessment by Route of Administration

• Assessment by Stage and Route of Administration

• Assessment by Molecule Type

• Assessment by Stage and Molecule Type

Diverticulitis– DelveInsight’s Analytical Perspective

In-depth Commercial Assessment

• Diverticulitis Disease companies’ collaborations, Licensing, Acquisition -Deal Value Trends

Diverticulitis Collaboration Deals

• Company-Company Collaborations (Licensing / Partnering) Analysis

• Company-University Collaborations (Licensing / Partnering) Analysis

Late Stage Products (Phase II/III)

• Comparative Analysis

Drug Name: Company Name

• Product Description

• Research and Development

• Product Development Activities

Mid Stage Products (Phase II)

• Comparative Analysis

Rifamycin: Salix Pharmaceuticals

• Product Description

• Research and Development

• Product Development Activities

Drug profiles in the detailed report…..

Early Stage Products (Phase I)

• Comparative Analysis

Glutamine: Emmaus Medical

• Product Description

• Research and Development

• Product Development Activities

Drug profiles in the detailed report…..

Pre-clinical and Discovery Stage Products

• Comparative Analysis

Drug Name: Company Name

• Product Description

• Research and Development

• Product Development Activities

Drug profiles in the detailed report…..

Inactive Products

• Comparative Analysis

Diverticulitis Key Companies

Diverticulitis Key Products

Diverticulitis- Unmet Needs

Diverticulitis- Market Drivers and Barriers

Diverticulitis- Future Perspectives and Conclusion

Diverticulitis Analyst Views

Diverticulitis Key Companies

Appendix

List of Table

Table 1 Total Products for Diverticulitis

Table 2 Late Stage Products

Table 3 Mid Stage Products

Table 4 Early Stage Products

Table 5 Pre-clinical & Discovery Stage Products

Table 6 Assessment by Product Type

Table 7 Assessment by Stage and Product Type

Table 8 Assessment by Route of Administration

Table 9 Assessment by Stage and Route of Administration

Table 10 Assessment by Molecule Type

Table 11 Assessment by Stage and Molecule Type

Table 12 Inactive Products

List of Figures

Figure 1 Total Products for Diverticulitis

Figure 2 Late Stage Products

Figure 3 Mid Stage Products

Figure 4 Early Stage Products

Figure 5 Preclinical and Discovery Stage Products

Figure 6 Assessment by Product Type

Figure 7 Assessment by Stage and Product Type

Figure 8 Assessment by Route of Administration

Figure 9 Assessment by Stage and Route of Administration

Figure 10 Assessment by Molecule Type

Figure 11 Assessment by Stage and Molecule Type

Figure 12 Inactive Products

• Salix Pharmaceuticals

• Emmaus Medical

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