Hypoparathyroidism Market

DelveInsight’s ‘Hypoparathyroidism -Market Insights, Epidemiology, and Market Forecast–2032’ report deliver an in-depth understanding of the Hypoparathyroidism , historical and forecasted epidemiology as well as the Hypoparathyroidism  market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.

The Hypoparathyroidism market report provides current treatment practices, emerging drugs, and market share of the individual therapies, current and forecasted 7MM Hypoparathyroidism market size from 2019 to 2032. The Report also covers current Hypoparathyroidism treatment practice, market drivers, market barriers, SWOT analysis, reimbursement, and market access, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.

Geography Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study Period: 2019–2032

Hypoparathyroidism Disease Understanding and Treatment Algorithm

Hypoparathyroidism (hypoPTH) is a rare condition in which the parathyroid glands fail to produce sufficient amounts of parathyroid hormone or lacks biological activity. The parathyroid glands are part of the endocrine system—the network of glands that secrete hormones into the bloodstream, where they travel to various body areas. These hormones regulate the chemical processes (metabolism) that influence various organs and activities within the body. Hormones are involved in numerous vital processes, including regulating heart rate, body temperature, blood pressure, cell differentiation and growth, and modulation of several metabolic processes. Parathyroid hormone (along with vitamin D and the hormone calcitonin, which is produced by the thyroid gland) plays a role in regulating the levels of calcium and phosphorus in the blood and in determining bone growth and bone cell activity. Due to a deficiency of the parathyroid hormone, individuals may exhibit abnormally low levels of calcium in the blood (hypocalcemia) and high levels of phosphorus (hyperphosphatemia).

Continued in the report…..

Hypoparathyroidism Diagnosis

A diagnosis of Hypoparathyroidism is made based upon the identification of characteristic symptoms, a detailed patient history, a thorough clinical evaluation, and a variety of specialized tests. Blood tests can reveal abnormal levels of calcium, phosphorus, magnesium, creatinine, and intact parathyroid hormone. Urine tests can reveal if the body is excreting too much calcium.

In addition, the Food and Drug Administration (FDA) has approved the use of the synthetic parathyroid hormone teriparatide as a diagnostic agent to distinguish hypoPTH from pseudohypoparathyroidism.

Additional tests may be performed to detect complications that may be associated with hypoPTH. For example, an electrocardiogram, a test that records the heart's electrical activity, can reveal arrhythmias that are sometimes associated with low calcium levels and Hypoparathyroidism. An ophthalmologic exam should also be done to check for cataracts.

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Hypoparathyroidism Treatment

Unlike most other hormonal deficits, hypoPTH is not treated with replacing the missing hormone, parathyroid hormone (PTH).

Currently, the standard treatment consists of activated vitamin D (calcitriol) and calcium supplements. Some people may also need magnesium supplementation. Conventional therapy requires many pills taken throughout the day.

Diet recommendations usually include eating foods high in calcium, such as dairy products, breakfast cereals, fortified orange juice, and green, leafy vegetables, or avoiding foods high in phosphorus, such as meat, poultry, fish, nuts, whole grains, and beans. Conventional therapy with vitamin D and calcium may lead to a buildup of calcium in the kidneys. This buildup may lead to problems, including kidney stones and deposits of calcium, reduced kidney function, tissue damage, or even kidney failure. In January 2015, the US Food and Drug Administration approved PTH 1-84 for adult hypoPTH patients who do not respond well to standard treatment as an add-on to that treatment

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Hypoparathyroidism Epidemiology  

The Hypoparathyroidism epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Prevalent Cases of Hypoparathyroidism, Diagnosed Prevalent Cases of Hypoparathyroidism, Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism, Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism, Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism and Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism scenario in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom) and Japan from 2019 to 2032.

Hypoparathyroidism Prevalence

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Hypoparathyroidism Key Findings

  • The total Hypoparathyroidism prevalent population in the 7MM ranges from 280,275 in 2021 growing at a CAGR of 1.23% during the study period [2019–2032].
  • The total diagnosed prevalent population of hypoparathyroidism in the United States ranges from 81,320 in 2021 growing at a CAGR of 1.50% during the study period [2019–2032].
  • Among the European five countries, United Kingdom had the highest prevalent population of hypoparathyroidism with 34,569 cases, followed by Germany and France in 2021. On the other hand, Spain had the lowest prevalent population.
  • Japan had 22,310 prevalent cases of hypoparathyroidism in 2021.
  • As per DelveInsight’s analysis, a higher percentage of Hypoparathyroidism prevalence was observed for females, in comparison to males, in all the 7MM countries.
  • According to DelveInsight’s analysis, it has been observed that hypoparathyroidism prevalence varied across the 7MM countries, based on the age-specific prevalence of the disease. For instance, the highest proportion was observed in the 65+ Years age group in the US, while in the EU-5 countries, people aged 55-64 Years accounted for the maximum patient pool.
  • Among the major types of hypoparathyroidism, i.e., Chronic and transient hypoparathyroidism, the former one accounts for a higher number of prevalent cases of hypoparathyroidism.

Country -Wise Hypoparathyroidism Epidemiology

The epidemiology segment also provides the Hypoparathyroidism epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

Hypoparathyroidism Drug Chapters

Hypoparathyroidism Emerging Drugs

TransCon PTH is an investigational prodrug of parathyroid hormone (PTH) and is under development as a once-daily hormone replacement therapy. It is designed to restore physiologic levels of PTH for 24 h each day. The company believes that this therapy can address both the short-term symptoms and long-term complications of hypoparathyroidism (HP).

The company’s goal is to provide a PTH replacement therapy that normalizes serum and urinary calcium, as well as serum phosphate levels, and improves the quality of life. In September 2020, the company submitted an amendment to IND to initiate PaTHway, a global Phase III clinical trial evaluating the safety, tolerability, and efficacy of the therapy in adults with HP following discussions with FDA and European regulatory authorities. In addition, the company is planning to conduct a Phase III study in Japan designed to evaluate the safety, tolerability, and efficacy of the therapy

Products detail in the report…

EB612: EnteraBio

EB612, an oral human parathyroid hormone (1-34) (PTH), the parathyroid glands are part of the endocrine system, a network of glands that secrete hormones into the bloodstream, which then travel to various areas of the body. PTH (along with vitamin D and the hormone calcitonin, which the thyroid gland produces) plays a role in regulating the levels of calcium and phosphorus in the blood. Due to a deficiency of PTH, individuals may exhibit abnormally low levels of calcium in the blood (hypocalcemia) and high levels of phosphorus (hyperphosphatemia). The common practice in treating these patients is with calcium and Vitamin D supplements at high doses in addition to other various drugs to treat the symptoms

Products detail in the report…

List to be continued in the report…

Hypoparathyroidism Market Outlook

Hypoparathyroidism is a rare condition in which the parathyroid glands fail to produce sufficient amounts of parathyroid hormone or the parathyroid hormone produced lacks biological activity. The parathyroid glands are part of the endocrine system, the network of glands that secrete hormones into the bloodstream, where they travel to various areas of the body. The severity of the condition can range from mild symptoms such as a tingling or numbness in the fingers, toes, or around the lips (paresthesias) to severe muscle cramps and muscle spasms.

The treatment of hypoparathyroidism is directed toward the specific symptoms that are apparent in each individual and the lab tests. Treatment is aimed at raising calcium levels high enough to provide symptom relief without causing abnormally high levels of calcium in the blood (hypercalcemia) or the urine (hypercalciuria). The specific therapies used may vary depending upon the disease severity, the specific symptoms present, an individual’s age and overall health, personal preference, and additional factors.

Oral calcium supplements can increase calcium levels in the blood. However, at high doses, calcium supplements can cause gastrointestinal side effects, such as constipation, in some people. There are several different types of calcium supplements available. Some brands may work better for certain people. High doses of vitamin D, generally in the form of calcitriol, can help the body absorb calcium and eliminate phosphorus. Another form of vitamin D that may be used is ergocalciferol or cholecalciferol. Outside the US, doctors use alpha calcidol. Ergocalciferol and cholecalciferol have a longer duration of action than calcitriol or alpha calcidol because the former two forms of vitamin D are stored in the body for long times.

If the magnesium level is low and the patient experiences symptoms of hypoparathyroidism, the doctor may recommend taking a magnesium supplement. If the calcium levels remain low even with treatment, thiazide diuretics can help decrease the amount of calcium lost through the urine. However, some people with hypoparathyroidism, including people who inherited the condition, should not take thiazide diuretics.

Some individuals, especially those with severe symptoms due to low blood calcium levels, may require immediate relief through intravenous calcium therapy, even if their calcium levels are only mildly reduced. Intravenous therapy means that a substance (e.g., calcium) is delivered into the bloodstream through an injection or infusion directly into a vein.

Furthermore, some may be encouraged to make dietary changes to help treat their condition. Affected individuals may be encouraged to eat foods high in calcium, such as dairy products, breakfast cereals, and fortified orange juice, and green, leafy vegetables.

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Hypoparathyroidism Market Size

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Hypoparathyroidism Key Findings

  • The Hypoparathyroidism market size in the 7MM was anticipated to be USD 235 million in 2021, and is anticipated to increase during the study period (2019–2032).
  • The current Hypoparathyroidism therapeutic landscape in the 7MM is driven by several approved therapy, including those with off-labelled products.
  • Natpara (parathyroid hormone/rhPTH [1-84]) is one and only approved drug for the treatment of hypoparathyroidism, which is approved in the US as well as in Europe.
  • Of all the Hypoparathyroidism therapies, in the 7MM the majority of the market share is accommodated by TransCon PTH, which is expected to generate market size of USD 1,342 million, in 2032. 

The United States: Hypoparathyroidism Market Outlook

This section provides the total Hypoparathyroidism market size and; market size by therapies in the United States.

EU-5: Hypoparathyroidism Market Outlook

The total Hypoparathyroidism market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.

Japan: Hypoparathyroidism Market Outlook

The total Hypoparathyroidism market size and market size by therapies in Japan are provided.

Hypoparathyroidism Drugs Uptake

This section focuses on the rate of uptake of the potential drugs recently launched in the Hypoparathyroidism market or expected to get launched in the market during the study period 2019–2032. The analysis covers the Hypoparathyroidism market uptake by drugs; patient uptake by therapies; and sales of each drug.  

This helps in understanding the Hypoparathyroidism drugs with the most rapid uptake, reasons behind the maximal use of new drugs, and allows the comparison of the drugs based on market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Hypoparathyroidism Development Activities

The report provides insights into different therapeutic candidates in phase II, and phase III stage. It also analyzes key players involved in developing targeted therapeutics.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition, and merger, licensing, and patent details for Hypoparathyroidism emerging therapies.

Reimbursement Scenario in Hypoparathyroidism

Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In the report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

Competitive Intelligence Analysis

We perform competitive and market Intelligence analysis of the Hypoparathyroidism market by using various competitive intelligence tools that include–SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability. 

Scope of the Report

  • The Hypoparathyroidism market report covers the descriptive overview of Hypoparathyroidism, explaining its causes, symptoms, pathophysiology, genetic basis, and currently available therapies.
  • Comprehensive insight has been provided into the Hypoparathyroidism epidemiology and treatment.
  • Additionally, an all-inclusive account of both the current and emerging therapies for Hypoparathyroidism is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape.
  • A detailed review of the Hypoparathyroidism market; historical and forecasted is included in the report, covering the 7MM drug outreach.
  • The report provides an edge while developing business strategies, by understanding trends shaping and driving the 7MM Hypoparathyroidism market.

Hypoparathyroidism Report Highlights

  • The robust pipeline with novel MOA and oral ROA, increasing prevalence, effectiveness of drugs as both mono and combination therapy will positively drive the Hypoparathyroidism market.
  • The companies and academics are working to assess challenges and seek opportunities that could influence Hypoparathyroidism R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition.
  • Major players are involved in developing therapies for Hypoparathyroidism. The launch of emerging therapies will significantly impact the Hypoparathyroidism market.
  • Our in-depth analysis of the pipeline assets across different stages of development (phase III and phase II), different emerging trends and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.

Hypoparathyroidism Report Insights

  • Hypoparathyroidism Patient Population
  • Hypoparathyroidism Therapeutic Approaches
  • Hypoparathyroidism Pipeline Analysis
  • Hypoparathyroidism Market Size
  • Hypoparathyroidism Market Trends
  • Hypoparathyroidism Market Opportunities
  • Impact of upcoming Hypoparathyroidism Therapies

Hypoparathyroidism Report Key Strengths

  • 11 Years Forecast
  • 7MM Coverage
  • Hypoparathyroidism  Epidemiology Segmentation
  • Key Cross Competition
  • Highly Analyzed Hypoparathyroidism Market
  • Hypoparathyroidism Drugs Uptake

Hypoparathyroidism Report Assessment

  • Current Treatment Practices
  • Hypoparathyroidism Unmet Needs
  • Hypoparathyroidism Pipeline Product Profiles
  • Hypoparathyroidism Market Attractiveness
  • Hypoparathyroidism Market Drivers
  • Hypoparathyroidism Market Barriers
  • SWOT analysis

 

Report Metrics

Details

Study Period

2019 to 2032

Base Year

2021

Forecast Period

2022 to 2032

CAGR

17.7%

Market Size

USD 235 million in 2021

Key Companies

Shire (Takeda), Ascendis Pharma, EnteraBio, Bridgebio, Calcilytix Therapeutics and Others.

Key Questions

Hypoparathyroidism Market Insights:

  • What was the Hypoparathyroidism market share (%) distribution in 2018 and how it would look like in 2032?
  • What would be the Hypoparathyroidism total market size as well as market size by therapies across the 7MM during the forecast period (2022–2032)?
  • What are the key findings pertaining to the market across the 7MM and which country will have the largest Hypoparathyroidism  market size during the forecast period (2022–2032)?
  • At what CAGR, the Hypoparathyroidism market is expected to grow at the 7MM level during the forecast period (2022–2032)?
  • What would be the Hypoparathyroidism market outlook across the 7MM during the forecast period (2022–2032)?
  • What would be the Hypoparathyroidism market growth till 2032 and what will be the resultant market size in the year 2032?
  • How would the market drivers, barriers, and future opportunities affect the market dynamics and subsequent analysis of the associated trends?

Hypoparathyroidism Epidemiology Insights:

  • What are the disease risk, burdens, and unmet needs of Hypoparathyroidism?
  • What is the historical Hypoparathyroidism patient pool in the United States, EU5 (Germany, France, Italy, Spain, and the UK), and Japan?
  • What would be the forecasted patient pool of Hypoparathyroidism at the 7MM level?
  • What will be the growth opportunities across the 7MM with respect to the patient population pertaining to Hypoparathyroidism?
  • Out of the above-mentioned countries, which country would have the highest prevalent population of Hypoparathyroidism during the forecast period (2022–2032)?
  • At what CAGR the population is expected to grow across the 7MM during the forecast period (2022–2032)?

Current Treatment Scenario, Marketed Drugs, and Emerging Therapies:

  • What are the current options for the treatment of Hypoparathyroidism along with the approved therapy?
  • What are the current treatment guidelines for the treatment of Hypoparathyroidism in the US and Europe?
  • What are the Hypoparathyroidism marketed drugs and their MOA, regulatory milestones, product development activities, advantages, disadvantages, safety, and efficacy, etc.?
  • How many companies are developing therapies for the treatment of Hypoparathyroidism?
  • How many emerging therapies are in the mid-stage and late stages of development for the treatment of Hypoparathyroidism?
  • What are the key collaborations (Industry–Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Hypoparathyroidism therapies?
  • What are the recent novel therapies, targets, mechanisms of action, and technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Hypoparathyroidism and their status?
  • What are the key designations that have been granted for the emerging therapies for Hypoparathyroidism?
  • What are the 7MM historical and forecasted market of Hypoparathyroidism?

Reasons to buy

  • The report will help in developing business strategies by understanding trends shaping and driving Hypoparathyroidism.
  • To understand the future market competition in the Hypoparathyroidism market and Insightful review of the key market drivers and barriers.
  • Organize sales and marketing efforts by identifying the best opportunities for Hypoparathyroidism in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors.
  • Organize sales and marketing efforts by identifying the best opportunities for the Hypoparathyroidism market.
  • To understand the future market competition in the Hypoparathyroidism market.

Frequently Asked Questions

What is Hypoparathyroidism?
Hypoparathyroidism (hypoPTH) is a rare condition in which the parathyroid glands fail to produce sufficient amounts of parathyroid hormone or lacks biological activity. The parathyroid glands are part of the endocrine system—the network of glands that secrete hormones into the bloodstream, where they travel to various body areas.
What was the Hypoparathyroidism market size in 2021?
The Hypoparathyroidism market size in the 7MM was anticipated to be USD 235 million in 2021, and is anticipated to increase during the study period (2019–2032).
Who are the leading companies in Hypoparathyroidism Market Landscape?
Some of the leading Hypoparathyroidism Companies working in the domain are Shire (Takeda), Ascendis Pharma, EnteraBio, Bridgebio, Calcilytix Therapeutics and Others.
What are the key strengths of Hypoparathyroidism Market Report?
Key strengths of Hypoparathyroidism Market Report are 11 Years Forecast, 7MM Coverage, Epidemiology Segmentation, Market Size, Drug Uptake, Pipeline Therapies, Market Drivers and Market Barriers.
Which country is expected to account for the most significant prevalent cases for Hypoparathyroidism in the 7MM?
The US is expected to account for the highest Hypoparathyroidism prevalent cases.

1. Key Insights

2. Report Introduction

3. Hypoparathyroidism Market Overview at a Glance

3.1. Market Share by Therapies (%) Distribution of Hypoparathyroidism in 2019

3.2. Market Share by Therapies (%) Distribution of Hypoparathyroidism in 2032

4. Future Prospects

5. Executive Summary of Hypoparathyroidism

6. Key Events

7. Disease Background and Overview

7.1. Introduction

7.2. Causes of Hypoparathyroidism

7.3. Symptoms of Hypoparathyroidism

7.4. Mechanisms/pathophysiology Hypoparathyroidism

7.5. Diagnosis of Hypoparathyroidism

7.5.1. Guidelines for diagnosis and evaluation

7.5.2. European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults

8. Treatment

8.1. Management of Hypoparathyroidism: Summary Statement and Guidelines

8.2. European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism (HypoPT) in adults

8.3. The American Association of Endocrine Surgeons Guidelines for Definitive Management of Primary Hyperparathyroidism

8.4. Standards of care for hypoparathyroidism in adults: a Canadian and International Consensus

9. Epidemiology and Patient Population

9.1. Key Findings

9.2. Epidemiology Methodology

9.3. Total Prevalent Cases of Hypoparathyroidism in the 7MM

9.4. Total Diagnosed Prevalent Cases of Hypoparathyroidism in the 7MM

9.5. Epidemiology of Hypoparathyroidism

9.6. The United States

9.6.1. Prevalent Cases of Hypoparathyroidism in the United States

9.6.2. Diagnosed Prevalent Cases of Hypoparathyroidism in the United States

9.6.3. Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States

9.6.4. Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States

9.6.5. Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States

9.6.6. Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States

9.7. EU5

9.7.1. Prevalent Cases of Hypoparathyroidism in EU5

9.7.2. Diagnosed Prevalent Cases of Hypoparathyroidism in EU5

9.7.3. Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5

9.7.4. Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5

9.7.5. Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5

9.7.6. Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5

9.8. Japan

9.8.1. Prevalent Cases of Hypoparathyroidism in Japan

9.8.2. Diagnosed Prevalent Cases of Hypoparathyroidism in Japan

9.8.3. Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan

9.8.4. Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan

9.8.5. Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan

9.8.6. Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan

10. Patient Journey

11. Marketed Drugs

11.1. Natpara (parathyroid hormone/rhPTH[1-84]): Shire (Takeda)

11.1.1. Product Description

11.1.2. Regulatory Milestones

11.1.3. Clinical Development

11.1.4. Clinical Trials Information

11.1.5. Safety and Efficacy

11.1.6. Product Profile

12. Emerging Therapies

12.1. Key Cross

12.2. TransCon PTH: Ascendis Pharma

12.2.1. Drug Description

12.2.2. Other Developmental Activities

12.2.3. Clinical Development

12.2.4. Clinical Trials Information

12.2.5. Safety and Efficacy

12.2.6. Product Profile

12.3. EB612: EnteraBio

12.3.1. Drug Description

12.3.2. Other Developmental Activities

12.3.3. Clinical Development

12.3.4. Clinical Trials Information

12.3.5. Safety and Efficacy

12.3.6. Product Profile

12.4. Encaleret (BBP-305/CLTX-305): Bridgebio/Calcilytix Therapeutics

12.4.1. Drug Description

12.4.2. Other Developmental Activities

12.4.3. Clinical Development

12.4.4. Clinical Trials Information

12.4.5. Safety and Efficacy

12.4.6. Product Profile

13. Potential of Current Therapies and Emerging Therapies

14. Hypoparathyroidism: Seven Major Market Analysis

14.1. Key Findings

14.2. Market Methodology

14.3. Market Size of Hypoparathyroidism in the 7MM in USD Million (2019–2032)

14.4. Market Size of Hypoparathyroidism by Therapies in the 7MM

14.5. Market Outlook

14.6. Attribute Analysis

14.7. Key Market Forecast Assumptions

14.8. United States Market Size

14.8.1. Total Market Size of Hypoparathyroidism in the United States

14.8.2. Market Size of Hypoparathyroidism by Therapies in the United States

14.9. EU-5 Market Size

14.9.1. Total Market size of Hypoparathyroidism in Europe

14.9.2. Market Size of Hypoparathyroidism by Therapies in Europe

14.10. Japan

14.10.1. Total Market size of Hypoparathyroidism in Japan

14.10.2. Market Size of Hypoparathyroidism by Therapies in Japan

15. KOL Views

16. Market Drivers

17. Market Barriers

18. SWOT Analysis

19. Unmet Needs

20. Reimbursement and Market Access

21. Appendix

21.1. Bibliography

21.2. Report Methodology

22. DelveInsight Capabilities

23. Disclaimer

24. About DelveInsight

List of Table

Table 1: Summary of Hypoparathyroidism Market, and Epidemiology (2019–2032)

Table 2: Key Events

Table 3: Acute and chronic manifestations of hypocalcemia and hypoparathyroidism

Table 4: Total Prevalent Cases of Hypoparathyroidism in the 7MM (2019–2032)

Table 5: Total Diagnosed Prevalent Cases of Hypoparathyroidism in the 7MM (2019-2032)

Table 6: Total Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Table 7: Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Table 8: Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the US (2019–2032)

Table 9: Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Table 10: Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Table 11: Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Table 12: Total Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Table 13: Total Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Table 14: Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Table 15: Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Table 16: Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Table 17: Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Table 18: Total Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Table 19: Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Table 20: Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Table 21: Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan(2019–2032)

Table 22: Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Table 23: Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Table 24: Natpara/rhPTH(1-84), Clinical Trial Description, 2022

Table 25: Comparison of emerging drugs under development

Table 26: TransCon PTH, Clinical Trial Description, 2022

Table 27: EB612, Clinical Trial Description, 2022

Table 28: Encaleret, Clinical Trial Description, 2022

Table 29: Market Size of Hypoparathyroidism in the 7MM in USD Million (2019–2032)

Table 30: Market Size of Hypoparathyroidism by therapies in the 7MM, in USD Million (2019–2032)

Table 31: Key Market Forecast Assumptions for Natpara

Table 32: Key Market Forecast Assumptions for TransCon PTH

Table 33: Key Market Forecast Assumptions for EB612

Table 34: Key Market Forecast Assumptions for Encaleret (BBP-305/CLTX-305)

Table 35: Market Size of Hypoparathyroidism by therapies in the US, in USD Million (2019–2032)

Table 36: EU5 Market Size of Hypoparathyroidism in USD Million (2019–2032)

Table 37: Market Size of Hypoparathyroidism by therapies in EU5, in USD Million (2019–2032)

Table 38: Japan Market Size of Hypoparathyroidism in USD Million (2019–2032)

Table 39: Market Size of Hypoparathyroidism by therapies in Japan, in USD Million (2019–2032)

List of Figures

Figure 1: Anatomy of Thyroid and parathyroid glands

Figure 2: Symptoms of Hypoparathyroidism

Figure 3: Total Prevalent Cases of Hypoparathyroidism in the 7MM (2019–2032)

Figure 4: Total Diagnosed Prevalent Cases of Hypoparathyroidism in the 7MM (2019–2032)

Figure 5: Total Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Figure 6: Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Figure 7: Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the US (2019–2032)

Figure 8: Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Figure 9: Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Figure 10: Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in the United States (2019–2032)

Figure 11: Total Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Figure 12: Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Figure 13: Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Figure 14: Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Figure 15: Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019-2032)

Figure 16: Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in EU5 (2019–2032)

Figure 17: Total Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Figure 18: Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Figure 19: Gender-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Figure 20: Type-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Figure 21: Age-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Figure 22: Cause-specific Diagnosed Prevalent Cases of Hypoparathyroidism in Japan (2019–2032)

Figure 23: Market Size of Hypoparathyroidism in the 7MM in USD Million (2019–2032)

Figure 24: Seven Major Market Size of Hypoparathyroidism by Therapies in the 7MM, in USD Million (2019–2032)

Figure 25: Market Size of Hypoparathyroidism in the US, USD Millions (2019–2032)

Figure 26: Market Size of Hypoparathyroidism in the US, USD Millions (2019–2032)

Figure 27: Market Size of Hypoparathyroidism by therapies in the United States, in USD Million (2019–2032)

Figure 28: Market Size of Hypoparathyroidism in EU5, USD Million (2019–2032)

Figure 29: EU5 Market Size of Hypoparathyroidism by Therapies in USD Million (2019–2032)

Figure 30: Market Size of Hypoparathyroidism in Japan, USD Million (2019–2032)

Figure 31: Japan Market Size of Hypoparathyroidism by Therapies in USD Million (2019–2032)

Figure 32: Market Drivers

Figure 33: Market Barriers

Figure 34: SWOT Analysis

Figure 35: Unmet Needs

Shire (Takeda)
Ascendis Pharma
EnteraBio
Bridgebio
Calcilytix Therapeutics

 

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