Merkel Cell Carcinoma collaborations, licensing, mergers and acquisition, funding, designations, and other product-related details, drug market 2030

Merkel Cell Carcinoma Pipeline Insight, pipeline drugs

DelveInsight&rsquo;s, &ldquo;Merkel Cell Carcinoma &ndash; Pipeline Insight, 2025,&rdquo; report provides comprehensive insights about 14+ companies and 14+ pipeline drugs in Merkel Cell Carcinoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
<h2>Geography Covered</h2>
<ul>
<li>Global coverage</li>
</ul>
<h2>Merkel Cell Carcinoma Understanding</h2>
Merkel Cell Carcinoma: Overview
Merkel cell carcinoma (MCC) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cells are located deep in the top layer of skin. Merkel cells are connected to nerves, signaling touch sensation as &ldquo;touch receptors.&rdquo; MCC tumors often, but not always, appear on sun-exposed areas of the body. The tumors are not nearly as distinctive as other skin cancers and can appear as a pearly pimple-like lump, sometimes skin-colored, red, purple or bluish-red, though they are rarely tender to the touch. Treatments for Merkel cell carcinoma can include: surgery, Radiation therapy, immunotherapy, and chemotherapy.
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"Merkel Cell Carcinoma - Pipeline Insight, 2025" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Merkel Cell Carcinoma pipeline landscape is provided which includes the disease overview and Merkel Cell Carcinoma treatment guidelines. The assessment part of the report embraces, in depth Merkel Cell Carcinoma commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Merkel Cell Carcinoma collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
<h2>Report Highlights</h2>
The companies and academics are working to assess challenges and seek opportunities that could influence Merkel Cell Carcinoma R&amp;D. The therapies under development are focused on novel approaches to treat/improve Merkel Cell Carcinoma.
<h2>Merkel Cell Carcinoma Emerging Drugs Chapters</h2>
This segment of the Merkel Cell Carcinoma report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
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Merkel Cell Carcinoma Emerging Drugs
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Domatinostat: 4SC
Domatinostat is an orally administered histone deacetylase (HDAC) inhibitor with a unique mode of action that was designed to strengthen the body&rsquo;s own anti-tumor immune response. Domatinostat &ldquo;opens&rdquo; the tumor microenvironment and encourages infiltration of immune cells into the tumor. To advance the development program, 4SC has also signed a drug supply agreement with Merck KGaA for avelumab (anti-PD-L1 antibody) to conduct a Phase II clinical trial of domatinostat in combination with avelumab in advanced-stage Merkel cell carcinoma (MCC) patients progressing on previous anti-PD-(L)1 monotherapy (MERKLIN 2).
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Cavrotolimod: Exicure
Cavrotolimod (AST-008) is a toll-like receptor 9 agonist designed to activate the innate immune system and induce a potent anti-cancer immune response, especially in combination with checkpoint inhibitors. During the first half of 2019, five clinical trial sites were opened and began dosing patients for the Phase I/II clinical trial. The Phase 1b stage was an open-label, multi-center trial designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of intratumoral cavrotolimod (AST-008) injections alone and in combination with intravenous pembrolizumab in patients with advanced solid tumors. The U.S. Food and Drug Administration (FDA) has granted two Fast Track designations to cavrotolimod (AST-008). Exicure initiated the Phase II stage of the clinical trial with dose-expansion cohorts of intratumoral cavrotolimod in combination with approved checkpoint inhibitors to treat two cohorts of patients with locally advanced or metastatic MCC or CSCC.
Further product details are provided in the report&hellip;&hellip;..
<h2>Merkel Cell Carcinoma: Therapeutic Assessment</h2>
This segment of the report provides insights about the different Merkel Cell Carcinoma drugs segregated based on following parameters that define the scope of the report, such as:
<ul>
<li>Major Players in Merkel Cell Carcinoma</li>
</ul>
There are approx. 14+ key companies which are developing the therapies for Merkel Cell Carcinoma. The companies which have their Merkel Cell Carcinoma drug candidates in the most advanced stage, i.e. Phase II include, 4SC.
<h2>Phases</h2>
DelveInsight&rsquo;s report covers around 14+ products under different phases of clinical development like
<ul>
<li>Late stage products (Phase III)</li>
<li>Mid-stage products (Phase II)</li>
<li>Early-stage product (Phase I) along with the details of</li>
<li>Pre-clinical and Discovery stage candidates</li>
<li>Discontinued &amp; Inactive candidates</li>
<li>Route of Administration</li>
</ul>
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Merkel Cell Carcinoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as 
<ul>
<li>Oral</li>
<li>Parenteral</li>
<li>Intravenous</li>
<li>Subcutaneous</li>
<li>Topical.</li>
<li>Molecule Type</li>
</ul>
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Products have been categorized under various Molecule types such as
<ul>
<li>Monoclonal Antibody</li>
<li>Peptides</li>
<li>Polymer</li>
<li>Small molecule</li>
<li>Gene therapy</li>
<li>Product Type</li>
</ul>
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
<h2>Merkel Cell Carcinoma: Pipeline Development Activities</h2>
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Merkel Cell Carcinoma therapeutic drugs key players involved in developing key drugs.
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Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Merkel Cell Carcinoma drugs.
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Learn how the therapeutic market will evolve and grow in the coming years:&nbsp;<a href="https://www.delveinsight.com/report-store/merkel-cell-carcinoma-market">Merkel Cell Carcinoma Market</a> &nbsp;
<h2>Merkel Cell Carcinoma Report Insights</h2>
<ul>
<li>Merkel Cell Carcinoma Pipeline Analysis</li>
<li>Therapeutic Assessment</li>
<li>Unmet Needs</li>
<li>Impact of Drugs</li>
</ul>
<h2>Merkel Cell Carcinoma Report Assessment</h2>
<ul>
<li>Pipeline Product Profiles</li>
<li>Therapeutic Assessment</li>
<li>Pipeline Assessment</li>
<li>Inactive drugs assessment</li>
<li>Unmet Needs</li>
</ul>
<h2>Key Questions</h2>
Current Treatment Scenario and Emerging Therapies:
<ul>
<li>How many companies are developing Merkel Cell Carcinoma drugs?</li>
<li>How many Merkel Cell Carcinoma drugs are developed by each company?</li>
<li>How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Merkel Cell Carcinoma?</li>
<li>What are the key collaborations (Industry&ndash;Industry, Industry&ndash;Academia), Mergers and acquisitions, licensing activities related to the Merkel Cell Carcinoma therapeutics?</li>
<li>What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?</li>
<li>What are the clinical studies going on for Merkel Cell Carcinoma and their status?</li>
<li>What are the key designations that have been granted to the emerging drugs?</li>
</ul>

Introduction
Executive Summary
Merkel Cell Carcinoma: Overview
<ul>
<li>Causes</li>
<li>Mechanism of Action</li>
<li>Signs and Symptoms</li>
<li>Diagnosis</li>
<li>Disease Management</li>
</ul>
Pipeline Therapeutics
<ul>
<li>Comparative Analysis</li>
</ul>
Therapeutic Assessment
<ul>
<li>Assessment by Product Type</li>
<li>Assessment by Stage and Product Type</li>
<li>Assessment by Route of Administration</li>
<li>Assessment by Stage and Route of Administration</li>
<li>Assessment by Molecule Type</li>
<li>Assessment by Stage and Molecule Type</li>
</ul>
Mid Stage Products (Phase II) 
<ul>
<li>Comparative Analysis</li>
</ul>
Domatinostat: 4SC
<ul>
<li>Product Description</li>
<li>Research and Development</li>
<li>Product Development Activities</li>
</ul>
Drug profiles in the detailed report&hellip;..
Early Stage Products (Phase I/II) 
<ul>
<li>Comparative Analysis</li>
</ul>
XmAb18087: Xencor
<ul>
<li>Product Description</li>
<li>Research and Development</li>
<li>Product Development Activities</li>
</ul>
Drug profiles in the detailed report&hellip;..
Preclinical stage products 
<ul>
<li>Comparative Analysis</li>
</ul>
SNS-401-NG: Sensei Biotherapeutics
<ul>
<li>Product Description</li>
<li>Research and Development</li>
<li>Product Development Activities</li>
</ul>
Drug profiles in the detailed report&hellip;..
Inactive Products
<ul>
<li>Comparative Analysis</li>
</ul>
Merkel Cell Carcinoma Key Companies
Merkel Cell Carcinoma Key Products
Merkel Cell Carcinoma- Unmet Needs
Merkel Cell Carcinoma- Market Drivers and Barriers
Merkel Cell Carcinoma- Future Perspectives and Conclusion
Merkel Cell Carcinoma Analyst Views
Merkel Cell Carcinoma Key Companies
Appendix

Merkel Cell Carcinoma - Pipeline Insight, 2025

Merkel Cell Carcinoma Pipeline Insights, 2025 report by DelveInsight outlays comprehensive insights of present clinical development scenario and growth prospects across the market