Non Small Cell Lung Cancer Nsclc Pipeline Insight

DelveInsight’s, “Non-Small-Cell Lung cancer (NSCLC) - Pipeline Insight, 2021,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Non-Small-Cell Lung cancer (NSCLC) pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

  • Global coverage

Non-Small-Cell Lung cancer (NSCLC) Understanding

Non-Small-Cell Lung cancer (NSCLC): Overview

Non-small-cell lung cancer (NSCLC) is any type of epithelial lung cancer other than small-cell lung cancer (SCLC) and accounts for about 85% of all lung cancers. There are three kinds of NSCLC tumors: a) Adenocancer starts in cells inside air sacs that make mucus and other substances, often in the outer parts of your lungs. It's the most common kind of lung cancer among both smokers and nonsmokers and people under 45. It often grows more slowly than other lung cancers. b) Squamous cell lung cancer starts in cells that line the inner airways of the lungs. About a quarter of lung cancers are this kind. c) Large cell (undifferentiated) cancer grows and spreads more quickly. That can make it tougher to treat. It's about 10% of lung cancers. An effective treatment for non-small cell adenocancer depends on the cancer’s stage. Surgery to remove all or only part of the lung is usually required if the cancer hasn’t spread.


"Non-Small-Cell Lung cancer (NSCLC)- Pipeline Insight, 2021" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Non-Small-Cell Lung cancer (NSCLC) pipeline landscape is provided which includes the disease overview and Non-Small-Cell Lung cancer (NSCLC) treatment guidelines. The assessment part of the report embraces, in depth Non-Small-Cell Lung cancer (NSCLC) commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Non-Small-Cell Lung cancer (NSCLC) collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Non-Small-Cell Lung cancer (NSCLC) R&D. The therapies under development are focused on novel approaches to treat/improve Non-Small-Cell Lung cancer (NSCLC).

Non-Small-Cell Lung cancer (NSCLC) Emerging Drugs Chapters

This segment of the Non-Small-Cell Lung cancer (NSCLC) report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.


Non-Small-Cell Lung cancer (NSCLC) Emerging Drugs


AMG 510: Amgen

AMG 510 is being developed by Amgen. Phase 1 clinical trials were completed in late 2020. Because the G12C KRAS mutation is relatively common in some cancer types, 14% of non-small-cell lung cancer adenocancer patients and 5% of colorectal cancer patients, and AMG 510 is the first drug candidate to target this mutation, there have been high expectations for the drug. The Food and Drug Administration has granted a fast track designation to AMG 510 for the treatment of metastatic non-small-cell lung cancer with the G12C KRAS mutation. The drug is in preregistration stage for the treatment of NSCLC.


CMP 001: Cytos Biotechnology

CMP 001 is a short piece of DNA, called an oligonucleotide that Checkmate designed to mimic the DNA of bacteria. It encapsulated the DNA in noninfectious virus-like particles, or VLPs. The company created CMP-001 to be administered directly to a tumor. When this occurs, the immune system sees VLPs as foreign. It generates immune cells called antigen presenting cells that release the DNA from the VLPs. CMP 001 is in phase 1 of clinical trials for the treatment of non-small cell lung cancer.

Further product details are provided in the report……..

Non-Small-Cell Lung cancer (NSCLC): Therapeutic Assessment

This segment of the report provides insights about the different Non-Small-Cell Lung cancer (NSCLC) drugs segregated based on following parameters that define the scope of the report, such as:

  • Major Players in Non-Small-Cell Lung cancer (NSCLC)

There are approx. 10+ key companies which are developing the therapies for Non-Small-Cell Lung cancer (NSCLC). The companies which have their Non-Small-Cell Lung cancer (NSCLC) drug candidates in the mid to advanced stage, i.e.Phase I include, Amgen.

Phases

DelveInsight’s report covers around 10+ products under different phases of clinical development like

  • Late-stage products (Phase III)
  • Mid-stage products (Phase II and Phase I/II)
  • Early-stage products (Phase I/II and Phase I) along with the details of 
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration


Non-Small-Cell Lung cancer (NSCLC) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as 

  • Subcutaneous
  • Intravenous
  • Oral
  • Parenteral
  • Intramuscular
  • Molecule Type


Products have been categorized under various Molecule types such as

  • Small molecules
  • Peptides
  • Polymer
  • Gene Therapy
  • Monoclonal antibodies
  • Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Non-Small-Cell Lung cancer (NSCLC): Pipeline Development Activities 

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Non-Small-Cell Lung cancer (NSCLC) therapeutic drugs key players involved in developing key drugs. 


Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Non-Small-Cell Lung cancer (NSCLC) drugs.

Non-Small-Cell Lung cancer (NSCLC) Report Insights

  • Non-Small-Cell Lung cancer (NSCLC) Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Non-Small-Cell Lung cancer (NSCLC) Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

  • How many companies are developing Non-Small-Cell Lung cancer (NSCLC) drugs?
  • How many Non-Small-Cell Lung cancer (NSCLC) drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Non-Small-Cell Lung cancer (NSCLC)?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Non-Small-Cell Lung cancer (NSCLC) therapeutics? 
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies? 
  • What are the clinical studies going on for Non-Small-Cell Lung cancer (NSCLC) and their status?
  • What are the key designations that have been granted to the emerging drugs? 

Introduction

Executive Summary

Non-Small-Cell Lung cancer (NSCLC): Overview

  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management

Pipeline Therapeutics

  • Comparative Analysis

Therapeutic Assessment

  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type

Non-Small-Cell Lung cancer (NSCLC) – DelveInsight’s Analytical Perspective

In-depth Commercial Assessment

  • Non-Small-Cell Lung cancer (NSCLC) companies’ collaborations, Licensing, Acquisition -Deal Value Trends
  • Non-Small-Cell Lung cancer (NSCLC) Collaboration Deals
  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis

Late Stage Products (Pre Registration)

  • Comparative Analysis

AMG 510: Amgen

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Mid Stage Products (Phase II)

  • Comparative Analysis

Drug Name: Company Name

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Early Stage Products (Phase I)

  • Comparative Analysis

CMP 001: Cytos Biotechnology

  • Product Description
  • Research and Development
  • Product Development Activities
  • Product Development Activities

Drug profiles in the detailed report…..

Inactive Products

  • Comparative Analysis

Non-Small-Cell Lung cancer (NSCLC) Key Companies

Non-Small-Cell Lung cancer (NSCLC) Key Products

Non-Small-Cell Lung cancer (NSCLC)- Unmet Needs

Non-Small-Cell Lung cancer (NSCLC)- Market Drivers and Barriers

Non-Small-Cell Lung cancer (NSCLC)- Future Perspectives and Conclusion

Non-Small-Cell Lung cancer (NSCLC) Analyst Views

Non-Small-Cell Lung cancer (NSCLC) Key Companies

Appendix

List of Table

Table 1: Total Products for Non-Small-Cell Lung cancer (NSCLC)

Table 2: Late Stage Products

Table 3: Mid Stage Products

Table 4: Early Stage Products

Table 5: Pre-clinical & Discovery Stage Products

Table 6: Assessment by Product Type

Table 7: Assessment by Stage and Product Type

Table 8: Assessment by Route of Administration

Table 9: Assessment by Stage and Route of Administration

Table 10: Assessment by Molecule Type

Table 11: Assessment by Stage and Molecule Type

Table 12: Inactive Products

List of Figures

Figure 1: Total Products for Non-Small-Cell Lung Cancer (NSCLC)

Figure 2: Late Stage Products

Figure 3: Mid Stage Products

Figure 4: Early Stage Products

Figure 5: Preclinical and Discovery Stage Products

Figure 6: Assessment by Product Type

Figure 7: Assessment by Stage and Product Type

Figure 8: Assessment by Route of Administration

Figure 9: Assessment by Stage and Route of Administration

Figure 10: Assessment by Molecule Type

Figure 11: Assessment by Stage and Molecule Type

Figure 12: Inactive Products


• GlaxoSmithKline

• Novartis

• AstraZeneca

• Eli Lilly and Company

• Pfizer Inc.

• F. Hoffmann-La Roche Ltd.

• Merck

• Millennium Pharmaceuticals, Inc.

• Boehringer Ingelheim Pharmaceuticals, Inc.

• Bristol Myers Squibb

• Sanofi

• IO Biotech

• Transgene

• Immutep S.A.

• Daiichi Sankyo, Inc.

• Regeneron Pharmaceuticals

• Hanmi Pharmaceutical Company Limited

• TYK Medicines, Inc

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