DelveInsight’s, “Non-Small Cell Lung Cancer (NSCLC) – Pipeline Insight, 2020,” report provides comprehensive insights about 200+ companies and 200+ pipeline drugs in Non-Small Cell Lung Cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Non-Small Cell Lung Cancer (NSCLC): Overview
Lung cancer is a type of cancer that starts in the lungs. Cancer starts when cells in the body begin to grow out of control. About 80% to 85% of lung cancers are Non-Small Cell Lung Cancer. The main subtypes of Non-Small Cell Lung Cancer are adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. These subtypes, which start from different types of lung cells are grouped together as Non-Small Cell Lung Cancer because their treatment and prognoses (outlook) are often similar.
The three main histological subtypes of Non-Small Cell Lung Cancer are:
Symptoms of lung cancer that are in the chest:
Tests that examine the lungs are used to diagnose and stage non-small cell lung cancer.
Treatment primarily involves surgery, chemotherapy, or radiation therapy. Because most lung cancers cannot be cured with currently available therapeutic modalities, the appropriate application of skilled palliative care is an important part of the treatment of patients with Non-Small Cell Lung Cancer.
This segment of the Non-Small Cell Lung Cancer report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Canakinumab is an interleukin (IL)-1β blocker that is being evaluated in CANOPY trial. CANOPY-A is a Phase III multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of canakinumab as adjuvant therapy in adult subjects with stages II-IIIA and NSCLC following complete surgical resection. The primary endpoint is disease-free survival
Libtayo is a fully-human monoclonal antibody targeting the immune checkpoint receptor PD-1 on T-cells. By binding to PD-1, Libtayo has been shown to block cancer cells from using the PD-1 pathway to suppress T-cell activation. The open-label, randomized, multi-center Phase 3 trial investigated the first-line treatment of Libtayo monotherapy compared to platinum-doublet chemotherapy in squamous or non-squamous advanced NSCLC that tested positive for PD-L1 in ≥50% of tumor cells. A separate Phase 3 trial evaluating a first-line combination of Libtayo and chemotherapy in patients with advanced NSCLC irrespective of PD-L1 expression is also underway and expected to be fully enrolled in 2020.
Further product details are provided in the report……..
This segment of the report provides insights about the different Non-Small Cell Lung Cancer drugs segregated based on following parameters that define the scope of the report, such as:
There are approx. 200+ key companies which are developing the therapies for Non-Small Cell Lung Cancer. The companies which have their Non-Small Cell Lung Cancer drug candidates in the mid to advanced stage, i.e. phase III and Phase II include, Spectrum Pharmaceuticals, Bristol-Myers Squibb, Merck, Eisai, Novartis Pharmaceuticals, Ariad Pharmaceuticals, Takeda, Regeneron Pharmaceuticals, Innovent Biologics etc.
DelveInsight’s report covers around 200+ products under different phases of clinical development like
Non-Small Cell Lung Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Products have been categorized under various Molecule types such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Non-Small Cell Lung Cancer therapeutic drugs key players involved in developing key drugs.
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Non-Small Cell Lung Cancer drugs.
Current Treatment Scenario and Emerging Therapies:
Introduction
Executive Summary
Non-Small Cell Lung Cancer: Overview
• Causes
• Mechanism of Action
• Signs and Symptoms
• Diagnosis
• Disease Management
Pipeline Therapeutics
• Comparative Analysis
Therapeutic Assessment
• Assessment by Product Type
• Assessment by Stage and Product Type
• Assessment by Route of Administration
• Assessment by Stage and Route of Administration
• Assessment by Molecule Type
• Assessment by Stage and Molecule Type
Non-Small Cell Lung Cancer – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
• Non-Small Cell Lung Cancer companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Non-Small Cell Lung Cancer Collaboration Deals
• Company-Company Collaborations (Licensing / Partnering) Analysis
• Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
• Comparative Analysis
Avelumab: Merck
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
• Comparative Analysis
Eftilagimod: Immutep Limited
• Product Description
• Research and Development
• Product Development Activities
Poziotinib: Hanmi Pharmaceutical Company Limited
• Product Description
• Research and Development
• Product Development Activities
Early Stage Products (Phase I)
• Comparative Analysis
DZD 9008: Dizal Pharmaceutical
• Product Description
• Research and Development
• Product Development Activities
TY-9591: TYK Medicines, Inc.
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Pre-clinical and Discovery Stage Products
• Comparative Analysis
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
• Comparative Analysis
Non-Small Cell Lung Cancer Key Companies
Non-Small Cell Lung Cancer Key Products
Non-Small Cell Lung Cancer- Unmet Needs
Non-Small Cell Lung Cancer- Market Drivers and Barriers
Non-Small Cell Lung Cancer- Future Perspectives and Conclusion
Non-Small Cell Lung Cancer Analyst Views
Non-Small Cell Lung Cancer Key Companies
Appendix
List of Tables
Table 1 Total Products for Non-Small Cell Lung Cancer
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
List of Figures
Figure 1 Total Products for Non-Small Cell Lung Cancer
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
• GlaxoSmithKline
• Novartis
• AstraZeneca
• Eli Lilly and Company
• Pfizer Inc.
• F. Hoffmann-La Roche Ltd.
• Merck
• Millennium Pharmaceuticals, Inc.
• Boehringer Ingelheim Pharmaceuticals, Inc.
• Bristol Myers Squibb
• Sanofi
• IO Biotech
• Transgene
• Immutep S.A.
• Daiichi Sankyo, Inc.
• Regeneron Pharmaceuticals
• Hanmi Pharmaceutical Company Limited
• TYK Medicines, Inc
