DelveInsight’s ‘West Syndrome - Market Insights, Epidemiology and Market Forecast– 2030’ report delivers an in-depth understanding of the West Syndrome, historical and forecasted epidemiology as well as the West Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
The West Syndrome market report provides current treatment practices, emerging drugs, and market share of the individual therapies, current and forecasted 7MM West Syndrome market size from 2017 to 2030. The report also covers current West Syndrome treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
Study Period: 2017–2030
West Syndrome Overview
West syndrome is an age-related specific epileptic encephalopathy due to multiple and diverse causes. It is characterized by a unique type of seizure called epileptic (infantile) spasms and gross EEG abnormalities of hypsarrhythmia. Usually, West syndrome consists of a characteristic triad: infantile spasms, the arrest of psychomotor development, and hypsarrhythmia, although one element may be missing. Spasms may be flexor, extensor, lightning, or nods, but most commonly they are mixed. Onset peaks are observed between the ages of 4–7 months and always occur before the age of 1 year. Also, boys are more commonly affected, and the prognosis is generally poor.
West syndrome may be separated into two groups: the symptomatic group, which is characterized by previous existence of brain damage signs (psychomotor retardation, neurologic signs, radiologic signs, or other types of seizures) or by a known etiology, and the smaller, cryptogenic group that is characterized by a lack of previous signs of brain damage and known etiology. The prognosis appears to be partly based on early therapy with adrenocorticotropic hormone or oral steroids. Besides, the ILAE new diagnostic scheme classifies West syndrome amongst ‘epileptic encephalopathies’ and prefers ‘epileptic spasms’ rather than ‘infantile spasms’.
It is a constellation of symptoms which are characterized by epileptic or infantile spasms, abnormal pattern of brain waves called hypsarrhythmia, and mental disability. The spasms that occur may range from violent jack-knife or “salaam” movements where the entire body bends in half, or they may change as little as a slight twitching of the shoulder or eye. These spasms usually start in the early months after birth, and medication can sometimes be used to help. They can also occur in elderly patients; they are called “epileptic spasms” rather than infantile spasms if this occurs.
West Syndrome Diagnosis
The diagnosis of infantile spasms is made by a detailed account of the seizures or history of someone who has seen them. Ideally, this will also include being able to watch some seizure videos. The video is especially helpful when the child is experiencing spasm clusters; this is because a variety of nonepileptic disorders (as well as colic) arise in infancy and can be confused with childhood spasms. West syndrome diagnosis is based on a combination of the clinical features and a typical EEG. The EEG’s pattern is rather disorganized, called hypsarrhythmia. EEG is often irregular in children with West syndrome, but the abnormality is often only seen during sleep. Infantile spasms and West syndrome have several different causes similar to many other epilepsy syndromes. In 7–8 out of every 10 children with West syndrome, one specific cause will be found.
Both children who have childhood spasms will require an EEG. Two EEGs may sometimes be needed. The first EEG is often done when the baby is awake, but if this does not show the pattern of hypsarrhythmia, then another EEG will be done when the baby sleeps. A magnetic resonance imaging (MRI) brain scan is also required for all children with infantile spasms and West syndrome. Also, they may need several additional tests, which involve blood checks, urine tests, and even other tests to try to determine the root cause of such a fluid stream from the spine.
West Syndrome Treatment
Therapy targets for children with childhood spasms are the highest quality of life (without seizures), fewest adverse effects from therapy, and the lowest number of drugs. Treatment may require a team of specialists to coordinate the efforts. Pediatrists, neurologists, surgeons and/or other health care professionals may need to plan treatment for an affected child systematically and comprehensively.
In some children, treatment with anticonvulsant drugs may help to reduce or control various types of West syndrome-related seizure activity. Adrenocorticotropic hormone (ACTH), prednisone, vigabatrin, and pyridoxine are among the most common medications used to treat epileptic spasms. The benefits of the drug must be compared with the risks of each treatment causing side effects. ACTH, prednisone and other steroids, for example, are known to cause immunosuppression problems, hypertension, inflammation, gastric problems, anxiety and irritability. Vigabatrin can cause deep structures in the MRI to cause permanent visual field defects, irritability and transient hyperintensities. There is no standard protocol for using ACTH or any other treatment with steroids. Whether high dose ACTH or low dose ACTH is effective is unknown, or whether prednisone use is more effective than ACTH.
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Prevalent Population of West Syndrome, Diagnosed Prevalent Population of West Syndrome and Gender-specific Diagnosed Prevalence of West Syndrome in the 7MM market covering the United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom) and Japan from 2017 to 2030.
Key Findings
This section provides glimpse of the West Syndrome epidemiology in the 7MM.
Country Wise- West Syndrome Epidemiology
The epidemiology segment also provides the West Syndrome epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.
The drug chapter segment of the West Syndrome report encloses the detailed analysis of West Syndrome marketed drugs and mid and late stage pipeline drugs. It also helps to understand the West Syndrome clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details of each included drug and the latest news and press releases.
West Syndrome Marketed Drugs
Sabril (Vigabatrin): Lundbeck
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although the drug is administered as a racemic mixture, only the S(+) enantiomer is pharmacologically active. It is an antiepileptic agent chemically unrelated to other anticonvulsants. It prevents the metabolism of GABA by irreversibly inhibiting GABA transaminase (GABA-T). Since, the drug is an irreversible inhibitor of gamma-aminobutyric acid transaminase (GABA-T), its duration of effect is thought to be dependent on the rate of GABA-T re-synthesis rather than on the rate of drug elimination. It is also indicated as monotherapy in the treatment of infantile spasms in patients between 1 month and 2 years of age for whom the potential benefits outweigh the risk of vision loss.
Product details in the report…
H.P. Acthar Gel: Questcor Pharmaceuticals/Mallinckrodt Pharmaceuticals
H.P. Acthar Gel is an adrenocorticotropic hormone (ACTH) analogue indicated as monotherapy for the treatment of infantile spasms in infants and children under 2 years of age and also indicated for the treatment of exacerbations of multiple sclerosis in adults. This gel was approved by the FDA in 1952 and has been used to treat IS for more than 50 years. It is recommended by the American Academy of Neurology and the Child Neurology Society as a treatment for IS. It was previously approved for various indications, including acute multiple sclerosis exacerbations and nephrotic syndrome. It is a purified preparation of adrenocorticotropic hormone (ACTH), obtained from the pituitary glands of pigs.
Product details in the report…
West Syndrome Emerging Drugs
Cannabidiol (CBD) oral solution: INSYS Therapeutics
Cannabidiol (CBD) oral solution is being developed by INSYS Therapeutics. It is a phytocannabinoid that belongs to the class of 113 cannabinoids in cannabis plants, accounting for up to 40% of the plants extract. CBD is found to act on cannabinoid (CB) receptors of the endocannabinoid system, which are found in numerous areas of the body, including the peripheral and central nervous systems, including the brain. The endocannabinoid system regulates many physiological responses of the body, including pain, memory, appetite, and mood. More specifically, CB1 receptors can be found within the pain pathways of the brain and spinal cord where they may affect CBD-induced analgesia and anxiolysis, and CB2 receptors have an effect on immune cells, where they may affect CBD-induced anti-inflammatory processes.
Product details in the report…
Epidiolex (GWP42003-P): GW Pharmaceuticals
Epidiolex (GWP42003-P), whose active product ingredient is cannabidiol, is an orally administered cannabinoid CB1 receptor antagonist for being investigated for the treatment of infantile spasms by GW Pharmaceuticals along with its US subsidiary Greenwich Biosciences. Epidiolex is GW pharmaceutical’s lead product and is a highly purified plant-derived (marijuana) cannabidiol.
CBD has been shown to have analgesic, anticonvulsant, muscle relaxant, anxiolytic, neuroprotective, anti-oxidant, and anti-psychotic activity. This wide variety of effects is likely due to its complex pharmacological mechanisms. In addition to binding to CB1 and CB2 receptors of the endocannabinoid system, there is evidence that CBD activates 5-HT1A serotonergic and TRPV1–2 vanilloid receptors, antagonizes alpha-1 adrenergic and µ-opioid receptors, inhibits synaptosomal uptake of noradrenaline, dopamine, serotonin and g-aminobutyric acid and cellular uptake of anandamide, acts on mitochondria Ca2 stores, blocks low-voltage-activated (T-type) Ca2 channels, stimulates the activity of the inhibitory glycine-receptor, and inhibits the activity of fatty amide hydrolase (FAAH).
Product details in the report…
JBPOS0101: BioPharm Solutions
JBPOS0101 is an antiepileptic drug candidate, which possesses highly potent and broad-spectrum antiepileptic activity as demonstrated in testing done by BioPharm Solutions and NIH NINDS Anticonvulsant Screening Program. It is an antagonist of metabotropic glutamate receptors 1 and 7. Additionally, JBPOS0101 may have a strong functional role in blood–brain barrier related neuroprotection against lithium-pilocarpine induced status epilepticus, collagenase induced hemorrhage and tPA induced cell death.
JBPOS0101 controls the occurrence of spasms directly and indirectly, and it works on the mGluR family receptor, including other unknown mechanisms. Unlike other existing drugs, it directly works on the ion channel related to the mode of action; as a result, it has a low probability of developing tolerance and has more extensive therapeutic coverage. The candidate has also been awarded orphan drug status for the West Syndrome.
Product details in the report…
• Sabril (Vigabatrin): Lundbeck
• H.P. Acthar Gel: Questcor Pharmaceuticals/Mallinckrodt Pharmaceuticals
• Cannabidiol (CBD) oral solution: INSYS Therapeutics
• Epidiolex (GWP42003-P): GW Pharmaceuticals
• JBPOS0101: BioPharm Solutions
• And Many More
This section of the report includes the dynamics of market scenario for West Syndrome in the 7MM, i.e., the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
The National Organization for Rare Disorders (NORD) defines West syndrome as a rare neurological syndrome with a constellation of symptoms characterized by epileptic/infantile spasms, abnormal brain wave patterns called hypsarrhythmia and intellectual disability. Any disorder that can lead to brain damage can be an underlying cause of West syndrome including trauma, brain malformations such as hemimegalencephaly or cortical dysplasia, infections, chromosomal abnormalities such as Down syndrome, or neurocutaneous disorders such as tuberous sclerosis complex (TSC). Since there are so many potential causes of West syndrome, treatment is based on the cause. It has been estimated that 0.31/1000 live births in the United States are affected by this syndrome.
Adrenocorticotropic hormone (ACTH), prednisone, vigabatrin, and pyridoxine are among the most common medications used to treat epileptic spasms. Nitrazepam, sodium valproate (Epilim) and zonisamide (Zonegran) may also be helpful in treatment. Apart from ACTH and prednisone, other types of corticosteroids such as prednisolone and hydrocortisone are also used. Other therapies, including the ketogenic diet and other anti-pileptics medications, may also prove useful in the treatment of infantile spasms.
The current market of West Syndrome possesses only two approved products, namely Sabril (vigabatrin) and Acthar Gel (corticotropin injection) to treat infantile spasms.
As per our analysis, the major pipeline drugs that are expected to enter the market of West Syndrome comprises of two cannabinoid therapies in phase III of clinical development, namely Cannabidiol (CBD) oral solution (INSYS Therapeutics) and Epidiolex (GW Pharmaceuticals). Another drug JBPOS0101 (Bio-Pharm Solutions) is an antiepileptic agent, which is being explored for the treatment of infantile spasms in phase II clinical trial in the US.
Key Findings
This section includes a glimpse of the West Syndrome 7MM market.
The United States Market Outlook
This section provides the total West Syndrome market size and market size by therapies in the United States.
EU-5 Market Outlook
The total aspregillosis market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.
Japan Market Outlook
The total West Syndrome market size and market size by therapies in Japan are provided.
This section focusses on the rate of uptake of the potential drugs recently launched in the West Syndrome market or expected to get launched in the market during the study period 2017–2030. The analysis covers West Syndrome market uptake by drugs; patient uptake by therapies; and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report provides insights into different therapeutic candidates in phase II, and phase III stage. It also analyzes key players involved in developing targeted therapeutics.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing and patent details for West Syndrome emerging therapies.
We perform competitive and market Intelligence analysis of the West Syndrome market by using various competitive intelligence tools that include–SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.
Market Insights:
Epidemiology Insights:
Current Treatment Scenario, Marketed Drugs and Emerging Therapies:
Which geography accounted for the largest West Syndrome market size?
The United States accounts for the largest market size of West Syndrome, in comparison to EU5 (the United Kingdom, Germany, Italy, France, and Spain) and Japan.
What was West Syndrome market size in 2017?
The market size of West Syndrome in the 7MM is estimated to be USD 171.10 Million in 2017.
What are the present West Syndrome market drivers?
Clinical Development Activities, Product Innovations and Technological Advancements, Support from Various Organizations and Growing Number of Births and Rising Prevalence of Infantile Spasms.
What are the West Syndrome market barriers?
Delayed Diagnosis and Treatment, Serious Side Effects of Medications, Lack of Prevalence-based Studies for Infantile Spasms , Challenges in Conducting Clinical Trials for Rare Diseases and Lack of Late Phase Clinical Studies.
Which are the leading companies in West Syndrome market?
Key Companies - Lundbeck, Questcor Pharmaceuticals/Mallinckrodt Pharmaceuticals, INSYS Therapeutics, GW Pharmaceuticals, BioPharm Solutions and several others.
How is epidemiology segmented for West Syndrome?
Total Incident Cases of West Syndrome in the 7MM, Gender-Specific Incidence of West Syndrome in the 7MM, Gender-Specific Incidence of West Syndrome in the 7MM, Incidence of West Syndrome by Extremities (%) in the 7MM, Stage-Specific Incidence of West Syndrome in the 7MM and Age-Specific Incidence of West Syndrome in the 7MM.
1 Key Insights
2 West Syndrome Market Overview at a Glance
2.1 Market Share (%) Distribution of West Syndrome in 2017
2.2 Market Share (%) Distribution of West Syndrome in 2030
3 Executive Summary of West Syndrome
4 West Syndrome: Disease Background and Overview
4.1 Introduction
4.2 Metabolic etiologies in West syndrome
4.3 Etiology-specific Subtypes of West syndrome
4.4 Causes and Risk Factors
4.5 Clinical Manifestations
4.6 Symptoms
4.7 Pathophysiology
4.8 Diagnosis
4.9 Differential Diagnosis
4.10 Prognosis
5 Diagnostic Algorithm for West Syndrome
6 Clinical Algorithm for Epileptic Spasms (Infantile Spasms) By Texas Children’s Hospital
7 Epidemiology and Patient Population
7.1 Key Findings
7.2 7MM Total Prevalent Population of West Syndrome
7.3 7MM Total Diagnosed Prevalent Population of West Syndrome
8 Country Wise-Epidemiology of West Syndrome
8.1 Assumptions and Rationale: 7MM Countries
8.2 United States
8.2.1 Assumptions and Rationale
8.2.2 Total Prevalent Population of West Syndrome in the United States
8.2.3 Total Diagnosed Prevalent Population of West Syndrome in the United States
8.2.4 Gender-specific Diagnosed Prevalent Population of West Syndrome in the United States
8.3 EU5 Countries
8.3.1 Assumptions and Rationale
8.4 Germany
8.4.1 Total Prevalent Population of West Syndrome in Germany
8.4.2 Total Diagnosed Prevalent Population of West Syndrome in Germany
8.4.3 Gender-specific Diagnosed Prevalent Population of West Syndrome in Germany
8.5 France
8.5.1 Total Prevalent Population of West Syndrome in France
8.5.2 Total Diagnosed Prevalent Population of West Syndrome in France
8.5.3 Gender-specific Diagnosed Prevalent Population of West Syndrome in France
8.6 Italy
8.6.1 Total Prevalent Population of West Syndrome in Italy
8.6.2 Total Diagnosed Prevalent Population of West Syndrome in Italy
8.6.3 Gender-specific Diagnosed Prevalent Population of West Syndrome in Italy
8.7 Spain
8.7.1 Total Prevalent Population of West Syndrome in Spain
8.7.2 Total Diagnosed Prevalent Population of West Syndrome in Spain
8.7.3 Gender-specific Diagnosed Prevalent Population of West Syndrome in Spain
8.8 United Kingdom
8.8.1 Total Prevalent Population of West Syndrome in the United Kingdom
8.8.2 Total Diagnosed Prevalent Population of West Syndrome in the United Kingdom
8.8.3 Gender-specific Diagnosed Prevalent Population of West Syndrome in the United Kingdom
8.9 Japan
8.9.1 Assumptions and Rationale
8.9.2 Total Prevalent Population of West Syndrome in Japan
8.9.3 Total Diagnosed Prevalent Population of West Syndrome in Japan
8.9.4 Gender-specific Diagnosed Prevalent Population of West Syndrome in Japan
9 Treatment
10 Treatment Algorithm for West Syndrome
11 Guidelines for the Management and Treatment of Infantile Seizures
11.1 Clinical Assessment
11.2 Interventions for treatment
12 Recognized Establishments
13 Unmet Needs
14 Marketed Profiles
14.1 Sabril (Vigabatrin): Lundbeck
14.1.1 Drug Description
14.1.2 Regulatory Milestones
14.1.3 Other Development Activities
14.1.4 Safety and Efficacy
14.1.5 Product Profile
14.2 H.P. Acthar Gel: Questcor Pharmaceuticals/Mallinckrodt Pharmaceuticals
14.2.1 Drug Description
14.2.2 Regulatory Milestones
14.2.3 Other Development Activities
14.2.4 Safety and Efficacy
14.2.5 Product Profile
15 Emerging Drugs
15.1 Key Competitors
15.2 Cannabidiol (CBD) oral solution: INSYS Therapeutics
15.2.1 Product Description
15.2.2 Other Development Activities
15.2.3 Clinical Development
15.2.4 Clinical Trials Information
15.2.5 Safety and Efficacy
15.2.6 Product Profile
15.3 Epidiolex (GWP42003-P): GW Pharmaceuticals
15.3.1 Product Description
15.3.2 Other Development Activities
15.3.3 Clinical Development
15.3.4 Clinical Trials Information
15.3.5 Product Profile
15.4 JBPOS0101: BioPharm Solutions
15.4.1 Product Description
15.4.2 Other Development Activities
15.4.3 Clinical Development
15.4.4 Product Profile
16 West Syndrome: 7 Major Market Analysis
16.1 Key Findings
16.2 Market Size of West Syndrome in the 7MM
17 The United States Market Outlook
17.1 United States Market Size
17.1.1 Total Market size of West Syndrome
17.1.2 Market Size by Therapies
18 EU-5 Countries: Market Outlook
18.1 Germany
18.1.1 Total Market size of West Syndrome
18.1.2 Market Size by Therapies
18.2 France
18.2.1 Total Market size of West Syndrome
18.2.2 Market Size by Therapies
18.3 Italy
18.3.1 Total Market size of West Syndrome
18.3.2 Market Size by Therapies
18.4 Spain
18.4.1 Total Market size of West Syndrome
18.4.2 Market Size by Therapies
18.5 United Kingdom
18.5.1 Total Market size of West Syndrome
18.5.2 Market Size by Therapies
19 Japan Market Outlook
19.1 Japan Market Size
19.1.1 Total Market size of West Syndrome
19.1.2 Market Size by Therapies
20 Case Reports
20.1 A 10-year-review of West syndrome Cases: Descriptive Analysis and Outcome Prognostic Factors (Spain)
20.2 Alexander Disease with Mild Dorsal Brainstem Atrophy and Infantile Spasms (Japan)
21 Market Drivers
22 Market Barriers
23 SWOT Analysis of West Syndrome
24 Appendix
24.1 Bibliography
24.2 Report Methodology
25 DelveInsight Capabilities
26 Disclaimer
27 About DelveInsight
List of Tables:
Table 1: Summary of West Syndrome, Market, Epidemiology and Key Events (2017–2030)
Table 2: Metabolic etiologies in Infantile Spasms
Table 3: Proportion of occurrence of different symptoms in West Syndrome patients
Table 4: Examinations to be conducted for West Syndrome
Table 5: Differential Diagnosis for Infantile spasms
Table 6: Total Prevalent Population of West Syndrome in the 7MM (2017–2030)
Table 7: Total Diagnosed Prevalent Population of West Syndrome in the 7MM (2017–2030)
Table 8: Total Prevalent Population of West Syndrome in the United States (2017–2030)
Table 9: Total Diagnosed Prevalent Population of West Syndrome in the United States (2017–2030)
Table 10: Gender-specific Diagnosed Prevalent Population of West Syndrome in the United States (2017–2030)
Table 11: Total Prevalent Population of West Syndrome in Germany (2017–2030)
Table 12: Total Diagnosed Prevalent Population of West Syndrome in Germany (2017–2030)
Table 13: Gender-specific Diagnosed Prevalent Population of West Syndrome in Germany (2017–2030)
Table 14: Total Prevalent Population of West Syndrome in France (2017–2030)
Table 15: Total Diagnosed Prevalent Population of West Syndrome in France (2017–2030)
Table 16: Gender-specific Diagnosed Prevalent Population of West Syndrome in France (2017–2030)
Table 17: Total Prevalent Population of West Syndrome in Italy (2017–2030)
Table 18: Total Diagnosed Prevalent Population of West Syndrome in Italy (2017–2030)
Table 19: Gender-specific Diagnosed Prevalent Population of West Syndrome in Italy (2017–2030)
Table 20: Total Prevalent Population of West Syndrome in Spain (2017–2030)
Table 21: Total Diagnosed Prevalent Population of West Syndrome in Spain (2017–2030)
Table 22: Gender-specific Diagnosed Prevalent Population of West Syndrome in Spain (2017–2030)
Table 23: Total Prevalent Population of West Syndrome in the United Kingdom (2017–2030)
Table 24: Total Diagnosed Prevalent Population of West Syndrome in the United Kingdom (2017–2030)
Table 25: Gender-specific Diagnosed Prevalent Population of West Syndrome in the United Kingdom (2017–2030)
Table 26: Total Prevalent Population of West Syndrome in the Japan (2017–2030)
Table 27: Total Diagnosed Prevalent Population of West Syndrome in Japan (2017–2030)
Table 28: Gender-specific Diagnosed Prevalent Population of West Syndrome in Japan (2017–2030)
Table 29: Treatment options for infantile spasms
Table 30: Recommendations for an approach to the infant with epilepsy suspected to have a metabolic condition
Table 31: Comparison of emerging drugs under development
Table 32: Cannabidiol (CBD) oral solution, Clinical Trial Description, 2020
Table 33: Epidiolex (GWP42003-P), Clinical Trial Description, 2020
Table 34: JBPOS0101, Clinical Trial Description 2020
Table 35: 7 Major Market Size of West Syndrome in USD Million (2017–2030)
Table 36: Total Market Size of West Syndrome in the United States, in USD Million (2017–2030)
Table 37: Market size of West Syndrome by therapies in the United States, in USD Million (2017–2030)
Table 38: Total Market Size of West Syndrome in Germany, in USD Million (2017–2030)
Table 39: Market size of West Syndrome by therapies in Germany, in USD Million (2017–2030)
Table 40: Total Market Size of West Syndrome in France, in USD Million (2017–2030)
Table 41: Market size of West Syndrome by therapies in France , in USD Million (2017–2030)
Table 42: Total Market Size of West Syndrome in Italy, in USD Million (2017–2030)
Table 43: Market size of West Syndrome by therapies in Italy, in USD Million (2017–2030)
Table 44: Total Market Size of West Syndrome in Spain, in USD Million (2017–2030)
Table 45: Market size of West Syndrome by therapies in Spain, in USD Million (2017–2030)
Table 46: Total Market Size of West Syndrome in the United Kingdom, in USD Million (2017–2030)
Table 47: Market size of West Syndrome by therapies in the United Kingdom, in USD Million (2017–2030)
Table 48: Total Market Size of West Syndrome in Japan, in USD Million (2017–2030)
Table 49:Market size of West Syndrome by therapies in Japan, in USD Million (2017–2030)
List of Figures:
Figure 1: Key Causes of West Syndrome
Figure 2: Symptoms of West Syndrome
Figure 3: Main characteristic symptoms of West Syndrome
Figure 4: Diagnostic Algorithm for West Syndrome
Figure 5: Clinical Algorithm for Epileptic Spasms (Infantile Spasms)
Figure 6: Total Prevalent Population of West Syndrome in the 7MM (2017–2030)
Figure 7: Total Diagnosed Prevalent Population of West Syndrome in the 7MM (2017–2030)
Figure 8: Total Prevalent Population of West Syndrome in the United States (2017–2030)
Figure 9: Total Diagnosed Prevalent Population of West Syndrome in the United States (2017–2030)
Figure 10: Gender-specific Diagnosed Prevalent Population of West Syndrome in the US (2017–2030)
Figure 11: Total Prevalent Population of West Syndrome in Germany (2017–2030)
Figure 12: Total Diagnosed Prevalent Population of West Syndrome in Germany (2017–2030)
Figure 13: Gender-specific Diagnosed Prevalent Population of West Syndrome in Germany (2017–2030)
Figure 14: Total Prevalent Population of West Syndrome in France (2017–2030)
Figure 15: Total Diagnosed Prevalent Population of West Syndrome in France (2017–2030)
Figure 16: Gender-specific Diagnosed Prevalent Population of West Syndrome in France (2017–2030)
Figure 17: Total Prevalent Population of West Syndrome in Italy (2017–2030)
Figure 18: Total Diagnosed Prevalent Population of West Syndrome in Italy (2017–2030)
Figure 19: Gender-specific Diagnosed Prevalent Population of West Syndrome in Italy (2017–2030)
Figure 20: Total Prevalent Population of West Syndrome in Spain (2017–2030)
Figure 21: Total Diagnosed Prevalent Population of West Syndrome in Spain (2017–2030)
Figure 22: Gender-specific Diagnosed Prevalent Population of West Syndrome in Spain (2017–2030)
Figure 23: Total Prevalent Population of West Syndrome in the United Kingdom (2017–2030)
Figure 24: Total Diagnosed Prevalent Population of West Syndrome in the United Kingdom (2017–2030)
Figure 25: Gender-specific Diagnosed Prevalent Population of West Syndrome in the UK (2017–2030)
Figure 26: Total Prevalent Population of West Syndrome in Japan (2017–2030)
Figure 27: Total Diagnosed Prevalent Population of West Syndrome in Japan (2017–2030)
Figure 28: Gender-specific Diagnosed Prevalent Population of West Syndrome in Japan (2017–2030)
Figure 29: Treatment algorithm for West Syndrome/ Infantile Spasms
Figure 30: Unmet Needs
Figure 31: 7 Major Market Size of West Syndrome in USD Million (2017–2030)
Figure 32: Total Market Size of West Syndrome in the United States, USD Millions (2017–2030)
Figure 33: Market size of West Syndrome by therapies in the United States, in USD Million (2017–2030)
Figure 34: Total Market Size of West Syndrome in Germany, USD Millions (2017–2030)
Figure 35: Market size of West Syndrome by therapies in Germany, in USD Million (2017–2030)
Figure 36: Total Market Size of West Syndrome in France, USD Millions (2017–2030)
Figure 37: Market size of West Syndrome by therapies in France, in USD Million (2017–2030)
Figure 38: Total Market Size of West Syndrome in Italy, USD Millions (2017–2030)
Figure 39: Market size of West Syndrome by therapies in Italy, in USD Million (2017–2030)
Figure 40: Total Market Size of West Syndrome in Spain, USD Millions (2017–2030)
Figure 41: Market size of West Syndrome by therapies in Spain, in USD Million (2017–2030)
Figure 42: Total Market Size of West Syndrome in the United Kingdom, USD Millions (2017–2030)
Figure 43: Market size of West Syndrome by therapies in the United Kingdom, in USD Million (2017–2030)
Figure 44: Total Market Size of West Syndrome in Japan, USD Millions (2017–2030)
Figure 45: Market size of West Syndrome by therapies in Japan, in USD Million (2017–2030)
Figure 46: Market Drivers
Figure 47: Market Barriers
Figure 48: SWOT Analysis of West Syndrome
• Sabril (Vigabatrin): Lundbeck
• H.P. Acthar Gel: Questcor Pharmaceuticals/Mallinckrodt Pharmaceuticals
• Cannabidiol (CBD) oral solution: INSYS Therapeutics
• Epidiolex (GWP42003-P): GW Pharmaceuticals
• JBPOS0101: BioPharm Solutions
• And Many More