Epidemiology Assessment

Objective:

Performing Deep Assessment to Understand the Epidemiological Scenario of Cutaneous Squamous Cell Carcinoma (cSCC)

The objective of this study was to conduct a comprehensive epidemiology assessment of Cutaneous Squamous Cell Carcinoma (cSCC) across multiple global regions. The focus was on evaluating the percentage of solid organ transplant recipients (SOTRs) who develop cSCC, with detailed insights spanning 15 countries, including the United States, major European markets, and key APAC regions.

This analysis aimed to help the client understand disease burden, patient risk segmentation, and country-wise epidemiological variations to support strategic planning and market insights.

Problem Statement

A US-based client sought a robust and data-driven epidemiological evaluation to quantify the incidence and risk of cSCC among solid organ transplant recipients across 15 geographically diverse countries.

They required:

• Country-specific estimates of SOTR populations
• Percentages and risk distribution of SOTRs developing Cutaneous Squamous Cell Carcinoma
• A consistent epidemiological framework for cross-country comparison
• Expert-backed validation through primary intelligence
  
  

This would support their internal asset evaluation, strategic planning, and future market landscape modeling.

Our Methodology

DelveInsight adopted a structured, two-tiered approach integrating secondary research and primary KOL validation to ensure accuracy and global relevance.

1. Secondary Assessment

Our epidemiology team conducted extensive secondary research using:

• Scientific literature and peer-reviewed epidemiology studies
• National transplant registries and global organ donation databases
• Country-level dermatology and oncology statistics
• Government health portals and disease burden reports
  
  

This helped establish baseline epidemiological inputs, prevalence ranges, and risk factors for cSCC in immunosuppressed populations.

2. Primary Assessment

To validate and refine secondary findings, DelveInsight performed:

• Interviews with Key Opinion Leaders (KOLs) across dermatology, oncology, and transplant medicine
• Consultations with regional experts from the US, EU5, and APAC
• Expert assessment of real-world incidence rates, treatment trends, and diagnostic challenges
  
  

Primary insights played a critical role in adjusting prevalence estimates and capturing country-specific variations in SOTR management and cSCC detection.

Results

DelveInsight delivered a detailed, data-rich epidemiology package containing:

Excel-Based Epidemiology Model

A dynamic model covering:

• Country-specific solid organ transplant populations
• Calculated percentages of SOTRs who develop cSCC
• Epidemiological segmentation by organ type, risk factors, and regional variation
  
  

Comprehensive PowerPoint Report

An executive summary presenting:

• Key epidemiology insights across all 15 countries
• Comparative analysis of cSCC burden in SOTRs
• Regional differences in transplant practices and cSCC incidence
  
  

In-Depth KOL Insights

Valuable qualitative intelligence including:

• Diagnostic challenges and screening patterns
• Risk factors influencing cSCC progression in immunosuppressed patients
• Expert commentary on unmet needs and disease management practices