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Pfizer’s TALA (talazoparib) in metastatic castration-resistant prostate cancer (mCRPC) |
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AstraZeneca and Merck’s Lynparza (olaparib) in Metastatic Castration-resistant Prostate Cancer (mCRPC) |
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Bayer Healthcare and Orion's Nubeqa (darolutamide) in Non-metastatic castration-resistant prostate cancer (nmCRPC) |
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Roche’s Ipatasertib (RG7440) in Metastatic Castration-resistant Prostate Cancer (mCRPC) |
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GSK has a strong say in ASCO 2020 as they are announcing key data on Cell Therapy and Next-generation Immuno-oncology |
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Can much awaited JAVELIN data give any surprise in ASCO 2020? |
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Another new combination approaches for front line multiple myeloma may bring a new option to patients |
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How effectively microsatellite instability-high/mismatch repair can be used for proper positioning in the Colorectal Cancer treatment landscape? |
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Another win for blockbuster Osimertinib (in an early stage of EGFR NSCLC) will further strengthen its potential in Lung Cancer |
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KEYNOTE-355: Randomized, double-blind, phase III study of pembrolizumab + chemotherapy versus placebo + chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative... |
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Alpelisib (ALP) + fulvestrant (FUL) in patients (pts) with PIK3CA-mutated (mut) hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2–) advanced breast cancer (ABC)... |
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PARSIFAL: A randomized, multicenter, open-label, phase II trial to evaluate palbociclib in combination with fulvestrant or letrozole in endocrine-sensitive patients with estrogen receptor (ER)[+]/HER2... |
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Association of tumor mutational burden (TMB) and clinical outcomes with pembrolizumab (pembro) versus chemotherapy (chemo) in patients with metastatic triple-negative breast cancer (mTNBC) from KEYNOT... |
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Results of ENCORE 602 (TRIO025), a phase II, randomized, placebo-controlled, doubleblinded, multicenter study of atezolizumab with or without entinostat in patients with advanced triple-negative breas... |
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A phase Ib/II study of eribulin (ERI) plus pembrolizumab (PEMBRO) in metastatic triplenegative breast cancer (mTNBC) (ENHANCE 1). |
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Phase II trial of bicalutamide in combination with palbociclib for the treatment of androgen receptor (+) metastatic breast cancer. |
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A phase Ib study to evaluate the oral selective estrogen receptor degrader GDC-9545 alone or combined with palbociclib in metastatic ER-positive HER2-negative breast cancer. |
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SOPHIA analysis by chemotherapy (Ctx) choice: A phase III (P3) study of margetuximab (M) + Ctx versus trastuzumab (T) + Ctx in patients (pts) with pretreated HER2+ metastatic (met) breast cancer (MBC)... |
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Preliminary safety, efficacy and pharmacokinetics (PK) results of KN026, a HER2 bispecific antibody in patients (pts) with HER2-positive metastatic breast cancer. |
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A phase Ib study of abemaciclib in combination with pembrolizumab for patients with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) locally advanced or metas... |
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Phase Ib trial to evaluate safety and anti-tumor activity of the AKT inhibitor, ipatasertib, in combination with endocrine therapy and a CDK4/6 inhibitor for patients with hormone receptor positive (H... |
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Phase I/II study of SAR439859, an oral selective estrogen receptor degrader (SERD), in estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-) metastatic breast canc... |
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23 |
Dual anti-CTLA-4 and anti-PD-1 blockade in metaplastic carcinoma of the breast: (DART=Dual Anti-CTLA-4 & Anti-PD-1 blockade in Rare Tumors) (SWOG S1609, Cohort 36). |
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A phase Ib trial of the cyclin-dependent kinase inhibitor dinaciclib (dina) in combination with pembrolizumab (P) in patients with advanced triple-negative breast cancer (TNBC) and response correlatio... |
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A phase III study of trastuzumab emtansine (T-DM1) + pertuzumab versus trastuzumab + pertuzumab + taxane, after anthracyclines as adjuvant therapy for high-risk HER2-positive early breast cancer (EBC) |
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IMvigor130 results might support the usage of combination of atezolizumab +/- platinum/gemcitabine as an important new treatment option for patients with untreated mUC. |
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Another missed trial of the ASCO 2020 as Adjuvant treatment with the PD-L1 inhibitor did not significantly improve disease-free survival (DFS) in patients with muscle-invasive bladder cancer |
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Promising results from IMbrave150 TRIAL of Atezolizumab + Bevacizumab may shift the treatment paradigsm for advanced HCC |
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Good clinical response for dual immune checkpoint inhibitors (Tremelimumab + Durvalumab) in second line HCC however, tough fight ahead in first line setting from much promising Atezolizumab + Bevacizu... |
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Long term follow up of Lifileucel treatment in a heavily pretreated metastatic melanoma patients who progressed on multiple prior therapies, including anti-PD1 and BRAF/MEK inhibitors |
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Future directions for Head and Neck treatment based on TMB studies |
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32 |
Long term follow up study of the use of pembrolizumab and its combination as first line treatment for recurrent/metastatic head and neck cancer |
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Encorafenib plus cetuximab with or without binimetinib for BRAF V600E metastatic colorectal cancer: Updated survival results from a randomized, three-arm, phase III study versus choice of either irino... |
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Pembrolizumab monotherapy for patients with advanced MSI-H colorectal cancer: Longerterm follow-up of the phase II, KEYNOTE-164 study. |
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Nivolumab (NIVO) + low-dose ipilimumab (IPI) as first-line (1L) therapy in microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): Two-year clinical... |
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A Phase II, multicenter, open-label study of trastuzumab deruxtecan in patients with HER2-expressing metastatic colorectal cancer |
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Interim analysis of ZUMA-5: A phase II study of axi-cel in pts with R/R iNHL |
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Lisocabtagene maraleucel (liso-cel) for treatment of 2L TNE R/R aggressive large B-cell NHL |
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Effect of enasidenib plus azacitidine (AZA) on Complete and overall response versus AZA monotherapy in mutant-IDH2 newly diagnosed AML |
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Tolerability and efficacy of anti-CD47 antibody magrolimab combined with azacitidine in MDS and AML: Phase Ib results |
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Glasdegib plus low-dose cytarabine in AML or MDS: BRIGHT AML 1003 final report and four-year OS follow-up |
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42 |
Five year results of a phase III study of CPX-351 versus 7+3 in older adults with newly diagnosed high-risk/secondary AML |
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43 |
6 month update: Phase III study of venetoclax plus low-dose cytarabine in previously untreated older patients with AML (VIALE-C) |
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Long-term survivors and gilteritinib safety post 1 year in FLT3-mutated R/R AML: ADMIRAL trial |
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Glasdegib in combination with azacitidine in patients with untreated higher-risk MDS, AML and CMML: Effects on marrow recovery and transfusion independence |
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CC-486 is safe and well-tolerated as maintenance therapy in patients >75 years with AML in first remission following induction chemotherapy: Phase III QUAZAR AML-001 trial |
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HRQoL in the phase III QUAZAR-AML-001 trial of CC-486 as maintenance therapy for patients with AML in first remission following induction chemotherapy |
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Venetoclax + intensive chemo with CLIA achieves high rates of durable complete remission with low rates of MRD in pts with newly diagnosed AML |
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49 |
Phase II study of lower-dose pracinostat plus azacitidine safety and efficacy in patients with high/very high-risk MDS |
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50 |
Phase I study of teclistamab, a dual-targeting immunotherapeutic, in relapse/refractory Multiple Myeloma |
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51 |
Initial results from phase III BOSTON study, comparing weekly selinexor + Vd versus twice weekly Vd in patients with R/R multiple myeloma |
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Initial KarMMa results : bb2121, a BCMA-targeted CAR T-cell therapy, in R/R multiple myeloma patients |
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Phase 1/2 update from EVOLVE study : orva-cel, a BCMA- directed CAR T cell therapy for patients with R/R multiple myeloma |
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Efficacy of SCRI-CAR19x22 T cell product in B-ALL and persistence of antiCD22 activity |
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Safety and efficacy results of GC027: The first-in-human, universal CART cell therapy for adult r/r T-ALL |
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56 |
Update of CARTITUDE-1: A phase Ib/II study of JNJ-4528, a BCMA-directed CAR-T-cell therapy, in R/R multiple myeloma |
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Primary analysis of phase II trial of VRd with/without elotuzumab for newly diagnosed multiple myeloma (SWOG-1211). |
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Depth of response to isatuximab + KRd (Isa-KRd) in front-line treatment of multiple myeloma: Interim analysis of the GMMG-CONCEPT trial |
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Updates from BELLINI, a phase III study of venetoclax or placebo in combination with Vd in R/R multiple myeloma |
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Selinexor, daratumumab, and dexamethasone in patients with R/R multiple myeloma |
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VRd superiority to lenalidomide, adriamycin, and dexamethasone (RAd) prior to risk-adapted transplant in newly diagnosed myeloma |
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Phase III TOURMALINE-MM4 : Ixazomib vs placebo maintenance for newly diagnosed multiple myeloma patients not undergoing ASCT |
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63 |
DREAMM-2 study: Single-agent belantamab mafodotin (GSK2857916) in patients with R/R multiple myeloma refractory to PI, IMiD, and anti-CD38 mAb |
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BELLINI study : Evaluation of MRD in R/R multiple myeloma patients treated with venetoclax or placebo with Vd |
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DREAMM-6: Safety and tolerability of belantamab mafodotin in combination with Vd in R/R multiple myeloma |
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First-in-human data of ALLO-501 and ALLO-647 in R/R LBCL/FL: ALPHA study |
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Comparison of efficacy and safety with obinutuzumab plus chemo vs. rituximab plus chemo in patients with previously untreated FL: Updates from phase III Gallium Study |
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First-line immunochemotherapy for FL in the GALLIUM study: Prognostic value of PET-CT status after long-term follow-up |
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Bosutinib for CP-CML after imatinib failure: 8-year update |
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Independent review: Arterial occlusive events due to ponatinib in PACE trial Ph+ CML |
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Bosutinib in patients with chronic phase chronic myeloid leukemia intolerant to prior tyrosine kinase inhibitors: Analyses from the BYOND study |
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KEYNOTE-204: Phase III study of Pembrolizumab vs Brentuximab vedotin in relapsed or refractory classic Hodgkin lymphoma |
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HALO Trial: Brentuximab vedotin and bendamustine as first-line treatment of Hodgkin lymphoma in the elderly |
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Frontline brentuximab vedotin as monotherapy or in combination for older Hodgkin lymphoma patients. |
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Gls-010 in Chinese patients with relapsed or refractory classical Hodgkin lymphoma: Impressive Phase II Results |
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Long-term follow-up of anti-CD19 CAR T-cell therapy for B-cell NHL and CLL |
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Safety and efficacy of optimized tandem CD19/CD20 CAR-engineered T cells in patients with R/R NHL |
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78 |
Phase I/II study of avadomide (CC-122) in combination with R-CHOP for newly diagnosed DLBCL |
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Phase I study of AUTO3 with pembrolizumab in patients with r/r DLBCL |
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Epcoritamab (GEN3013) to induce CR in pts with R/R B-NHL: Complete dose escalation data and efficacy results from a phase I/II trial |
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Retreatment of pts with refractory DLBCL with axi-cel in ZUMA-1 |
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Final results of Lenalidomide plus R-GDP (R2-GDP) - GOTEL in relapsed/refractory diffuse large B-cell lymphoma |
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RE-MIND study: A propensity score-based 1:1 matched comparison of tafasitamab + lenalidomide (L-MIND) versus lenalidomide monotherapy in transplant-ineligible pts with R/R DLBCL |
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Outpatient treatment with liso-cel across a variety of clinical sites from three ongoing clinical studies in R/R LBCL. |
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Atezolizumab + obinutuzumab + venetoclax in patients with R/R DLBCL: Primary analysis of a phase II trial from LYSA |
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Finally Opdivo in combination with Yervoy has got success in much awaited lucrative first line NSCLC patients whose tumors express PD-L1≥1% and approval is further supported by long term data |
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Wthin a space of 11 days, Opdivo-Yervoy with chemo bagged another approval in first line NSCLC irrespective of PD-L1 expression |
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Frontline durvalumab and tremelimumab combo misses overal survival endpoint in metastatic NSCLC |
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Another new combination of tiragolumab and atezolizumab has shown efficacy signals in lucrative first line NSCLC |
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Novartis unveils more capmatinib data from GEOMETRY mono-1 study |
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Osimertinib trial results in NSCLC patients with EGFR exon 20 insertions from ECOG-ACRIN 5162 trial |
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Roche presented long term data of alectinib from ALEX study in frontline advanced ALK+ NSCLC |
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Another MET inhibitor expected to make their way in METex14+ mutated NSCLC |
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Novartis presented the data from GEOMETRY mono-1 study to support the capmatinib usage in second line setting |
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Takeda published brigatinib data from J-ALTA study to supprt its approval in Japanese patients |
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96 |
Heat Biologics's allogeneic cellular vaccine in combination with nivolumab shown efficacy signals in phase I/II data |
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97 |
Pembrolizumab usage along with radiothreapy associated with better efficacy outcomes |
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Merck presented the data from VISION study to support its FDA approval in patients with NSCLC with METex14 skipping |
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Two year follow up data of bintrafusp alfa presented by Merck with encouraging efficacy signals |
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CheckMate 568 Part 2 data will further support the approval of nivolumab plus ipilimumab with two cycles of chemotherapy combo in firstline NSCLC setting |
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Pegilodecakin did not show any improvement in efficacy when added to pembrolizumab in first line NSCLC |
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Data from exploratory RELAY+ study of ramucirumab plus gefitinib supports its usage in first line EGFR mutated NSCLC |
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Phase II study of venetoclax plus dose-adjusted R-EPOCH for Richter’s syndrome |
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104 |
Good interim data from phase 2 trial of first-line pembrolizumab and vorinostat in patients with metastatic NSCLC |
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Initial results of MRD driven time limited therapy with zanubrutinib, obinutuzumab, and venetoclax |
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Novartis presented Phase II data of one more promising irreversible 3rd-generation EGFR TKI |
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TAK-788 vs real-world data outcomes in refractory non-small cell lung cancer (NSCLC) with EGFR exon 20 insertions |
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108 |
Acalabrutinib versus idelalisib plus rituximab or bendamustine plus rituximab in R/R CLL: ASCEND final results |
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Final data of KEYNOTE-189 study in patients with newly diagnosed metastatic nonsquamous NSCLC |
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110 |
Updated overall survival (OS) and genomic analysis from a single-arm phase II study of dabrafenib + trametinib in patients with BRAF V600E mutant metastatic NSCLC |
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Patient-reported outcomes (PROs) in the randomized, phase III IMpower110 study of atezolizumab (atezo) vs chemotherapy in 1L metastatic NSCLC |
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Effect of adding ublituximab to ibrutinib on efficacy in previously treated high-risk CLL: GENUINE phase III study |
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113 |
Some supporting data of Lorlatinib; irreversible 3rd-generation EGFR TKI in patients with ALK-positive NSCLC |
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Mute response of Durvalumab trial as Durvalumab plus tremelimumab fails to show the clinical activity in patients with acquired resistance to PD-1 checkpoint inhibitors |
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Acalabrutinib in treatment-naïve CLL: Mature results from Ph II study demonstrating durable remissions and longterm tolerability |
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116 |
Fixed-duration venetoclax-obinutuzumab for previously untreated pts with CLL: Follow-up results from phase III CLL14 trial |
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117 |
Supportive data from Nivolumab trial for its use as monotherapy or in combination with cisplatin/carboplatin and etoposide as frontline therapy for extensive-stage small cell lung cancer (ES-SCLC) |
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Phase III MURANO study results: Impact of premature venetoclax discontinuation/interruption on outcomes in R/R CLL |
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119 |
Consistent result of tazemetostat in terms of Efficacy, safety, and immune priming effect in patients with epithelioid sarcoma. |
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120 |
Eribulin and pembrolizumab disappointed with its efficacy results in Uterine leiomyosarcoma (LMS) |
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121 |
Role of CDK4/6 inhibitors in treating advanced Soft Tissue Sarcoma (STS) |
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Highest reported efficacy of doxorubicin + pembrolizumab till date in a preliminary advanced STS trial |
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AKT inhibition by Ipatasertib in mCRPC: The A.MARTIN Randomized Phase II trial |
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Updated results from ARAMIS phase III trial showed darolutamide improves overall survival (OS) over placebo in nmCRPC patients |
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125 |
Updated overall survival results from PROSPER: A phase III, randomized, double-blind, placebo controlled study of enzalutamide (ENZA) in men with nmCRPC |
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Apalutamide Plus ADT Leads to Significantly Improved Outcomes in Nonmetastatic CRPC: Results from the phase III SPARTAN trial |
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Novel AKT inhibitor fails to demonstrate a difference in the primary outcome of PFS: Results from phase II ProCAID trial |
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128 |
Pembrolizumab plus enzalutamide in patients with abiraterone acetate pretreated mCRPC: KEYNOTE-365 cohort C efficacy, safety, and biomarker results |
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129 |
HERO phase III trial: Results comparing relugolix, an oral GnRH receptor antagonist, versus leuprolide acetate for advanced prostate cancer |
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Impact of Olaparib vs Physician’s Choice of New Hormonal Agent On Burden of Pain in mCRPC: Results from PROfound |
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131 |
AstraZeneca presented the Health-related quality of life (HRQoL) data for olaparib versus enzalutamide or abiraterone in mCRPC with HRR gene alterations |
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132 |
Exelixis reports data from Phase 1b COSMIC-021 Trial of Cabozantinib in Combination With Atezolizumab in Patients With mCRPC |
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Pfizer has presented the positive interim data of PARP inhibitor from the TALAPRO-1 phase II trial |
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Data from CARD study Confirm Benefit of Cabazitaxel Over Abiraterone or Enzalutamide in mCRPC |
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135 |
Much awaited result of Trastuzumab + trimodality treatment for HER2+ esophageal adenocarcinoma brought disappointment with its failure in reaching the primary end point |
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136 |
No significant survival benefit of pembrolizumab over 2L paclitaxel in previusly treated PD-L1+ advanced gastric or gastroesophageal junction cancer |
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137 |
Tumor mutational burden (TMB) demonstrates a positive association with clinical outcomes with pembrolizumab in gastric cancer |
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Another PD-1 inhibitor (Sintilimab) jointly developed by Innovent and Eli Lilly has met its primary endpoint of overall survival in the second-line treatment of patients with metastatic esophageal squ... |
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In gastric cancer no treatment till date has shown such a strong data, Definately Enhetru will be positioned much ahead of Kadcyla |
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140 |
A rare failure of Olaparib brought a lot of disappointment for ovarian cancer patient community |
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141 |
Role of DOCK8, EP 400, and PDX1 mutations as prognostic biomarkers & its association with longer survival in patients treated with Selinexor. |
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142 |
Role of MDNA55 (Interleukin-4 Receptor) in a difficult to treat population (de novo GBM, IDH wild-type, not eligible for surgery at recurrence) & its benefit for patient resistant to temozolomide. |
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143 |
Another novel combination approach (INO-5401 + INO-9012 with Cemiplimab) for newly diagnosed GBM patients |
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Not so encouraging results for Atezolizumab in comination of Temozolomide for newly diagnosed GBM |
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145 |
Savolitinib can be a better treatment choice than sunitinib due to its improved efficacy and safety profile |
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146 |
Results from TIVO-3 supports use of Tivozanib for highly treatment refractory RCC patients |
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Not very promising but Cabozantinib is an effective treatment option for the patients with advanced refractory RCC |
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148 |
The result from KEYNOTE-426 warrants the use of pembrolizumab and axitinib as a standard of care for patients with previously untreated RCC |
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149 |
Lenvatinib plus Pembrolizumab shows strong data for mccRCC with disease progression following prior PD-1/PDL-1 therapy |
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150 |
Tumor Mutation Burden (TMB): One Size fits for all? Not really! |
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Lilly overthrows Pfizer in Early HR+/HER2- Breast Cancer, what Next? |
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152 |
ESMO 2020 – Major trials in focus and Our View Points |
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153 |
Triumphs and Troubles for Combination Therapies in Melanoma: COMBI-I Trial Failure Story |
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154 |
Will ADC’s be in focus in ESMO 2020 too? |
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BMS/Exelixis face-off with Merck’s Keytruda in front-line renal cancer |
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156 |
Gilead's ASCENT into Oncology: Sacituzumab results at ESMO 2020 |
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157 |
ADAURA trial results presented at ESMO established proven clinical activity of Tagrisso (osimertinib) in the adjuvant treatment of early-stage EGFR-mutated lung cancer (EGFRm) |
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ASCENT trial results establish Sacituzumab as new standard of care in third line for metastatic TNBC |
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159 |
Promising results from the CROWN trial supports Lorbrena (lorlatinib) as a future first-line standard treatment in ALK+ NSCLC |
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ESMO 2020: CheckMate 9ER Provides New First-Line Treatment Option for Patients Advanced RCC |
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161 |
Head & Neck Cancers ESMO 2020 Insights |
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Health-related quality of life (HRQoL) in patients (pts) treated with pembrolizumab (pembro) vs chemotherapy as first-line treatment in microsatellite instability-high (MSI-H) and/or deficient mismatc... |
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163 |
Avelumab plus cetuximab in pre-treated RAS wild type metastatic colorectal cancer patients as a rechallenge strategy: The phase II CAVE (cetuximab-avelumab) mCRC study |
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164 |
Trastuzumab deruxtecan (T-DXd; DS-8201) in patients with HER2-low, advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma: Results of the exploratory cohorts in the phase II, multicenter,... |
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165 |
Phase I/II study with CXCL12 inhibitor NOX-A12 and pembrolizumab in patients with microsatellite-stable, metastatic colorectal or pancreatic cancer |
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166 |
Ipatasertib (IPAT) + paclitaxel (PAC) for PIK3CA/AKT1/PTEN-altered hormone receptor-positive (HR+) HER2- negative advanced breast cancer (aBC): Primary results from Cohort B of the IPATunity130 random... |
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167 |
Overall survival (os) results from SOLAR-1, a phase III study of alpelisib (ALP) + fulvestrant (FUL) for hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2–) adva... |
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168 |
PALLAS: A randomized phase III trial of adjuvant palbociclib with endocrine therapy versus endocrine therapy alone for HR+/HER2- early breast cancer |
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169 |
nextMONARCH: Final overall survival analysis of abemaciclib monotherapy or in combination with tamoxifen in patients with HR+, HER2- metastatic breast cancer |
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170 |
Primary results from IMpassion131, a double-blind placebo-controlled randomised phase III trial of first-line paclitaxel (PAC) ± atezolizumab (atezo) for unresectable locally advanced/metastatic tripl... |
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IMpassion130: Final OS analysis from the pivotal phase III study of atezolizumab + nab-paclitaxel vs placebo + nab-paclitaxel in previously untreated locally advanced or metastatic triple-negative bre... |
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172 |
IMpassion031: Results from a phase III study of neoadjuvant (neoadj) atezolizumab + chemotherapy in early triple-negative breast cancer (TNBC) |
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173 |
Pembrolizumab versus placebo after complete resection of high-risk stage III melanoma: Final results regarding distant metastasis-free survival from the EORTC 1325-MG/Keynote 054 double-blinded phase... |
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174 |
Spartalizumab plus dabrafenib and trametinib (Sparta-DabTram) in patients (pts) with previously untreated BRAF V600–mutant unresectable or metastatic melanoma: Results from the randomized part 3 of th... |
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175 |
Lenvatinib (len) plus pembrolizumab (pembro) for advanced melanoma (MEL) that progressed on a PD-1 or PD-L1 inhibitor: Initial results of LEAP-004 |
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176 |
Adjuvant nivolumab (NIVO) vs ipilimumab (IPI) in resected stage III/IV melanoma: 4-y recurrence-free and overall survival (OS) results from CheckMate 238 |
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177 |
Estimating long-term survivorship in patients with advanced melanoma treated with immune-checkpoint inhibitors: Analyses from the phase III CheckMate 067 trial |
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178 |
First report of efficacy and safety from the phase II study SECOMBIT (SEquential COMBo Immuno and Targeted therapy study) |
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179 |
LEAP-005: Phase II study of lenvatinib (len) plus pembrolizumab (pembro) in patients (pts) with previously treated advanced solid tumours |
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180 |
Durability of clinical benefit and biomarkers in patients (pts) with advanced non-small cell lung cancer (NSCLC) treated with AMG 510 (sotorasib) |
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181 |
Amivantamab (JNJ-61186372), an EGFR-MET bispecific antibody, in combination with lazertinib, a 3rd-generation tyrosine kinase inhibitor (TKI), in advanced EGFR NSCLC |
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182 |
Exploratory patient-reported outcomes among patients with RET-mutant medullary thyroid cancer in LIBRETTO-001: A phase I/II trial of selpercatinib (LOXO-292) |
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183 |
POD1UM-201: A phase II study of retifanlimab (INCMGA00012) in advanced or metastatic Merkel cell carcinoma (MCC) |
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184 |
Phase I Alexander study of AUTO3, the first CD19/22 dual targeting CAR.T cell, with pembrolizumab in patients with relapsed/refractory (r/r) DLBCL |
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185 |
Phase 2 Trial of Lenvatinib + Pembrolizumab for Progressive Disease After PD-1/PD-L1 Immune Checkpoint Inhibitor in Metastatic Clear Cell Renal Cell Carcinoma: Results by Independent Imaging Review an... |
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186 |
Phase II study of the oral HIF-2α inhibitor MK-6482 for Von Hippel-Lindau (VHL) disease-associated clear cell renal cell carcinoma (ccRCC): Update on RCC and non-RCC disease |
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187 |
A phase III, randomized, open-label study of first-line durvalumab (D) with or without tremelimumab (T) vs standard of care chemotherapy in patients with unresectable, locally advanced or metastatic u... |
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188 |
Long-term outcomes from KEYNOTE-048: Pembrolizumab (pembro) alone or with chemotherapy (pembro+C) vs EXTREME (E) as first-line (1L) therapy for recurrent/metastatic (R/M) head and neck squamous cell c... |
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189 |
Primary results of the phase III JAVELIN head & neck 100 trial: Avelumab plus chemoradiotherapy (CRT) followed by avelumab maintenance vs CRT in patients with locally advanced squamous cell carcinoma... |
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190 |
Pembrolizumab versus cetuximab, concomitant with radiotherapy (RT) in locally advanced head and neck squamous cell carcinoma (LA-HNSCC): Results of the GORTEC 2015-01 “PembroRad” randomized trial |
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191 |
TROPHY-U-01 cohort 1 final results: A phase II study of sacituzumab govitecan (SG) in metastatic urothelial cancer (mUC) that has progressed after platinum (PLT) and checkpoint inhibitors (CPI) |
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192 |
Pembrolizumab plus chemotherapy versus chemotherapy as first-line therapy in patients with advanced esophageal cancer: The phase 3 KEYNOTE-590 study |
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193 |
Nivolumab (nivo) plus chemotherapy (chemo) versus chemo as first-line (1L) treatment for advanced gastriccancer/gastroesophageal junction cancer (GC/GEJC)/esophageal adenocarcinoma (EAC): First result... |
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194 |
Adjuvant nivolumab in resected esophageal or gastroesophageal junction cancer (EC/GEJC) following neoadjuvant chemoradiation therapy (CRT): First results of the CheckMate 577 study |
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195 |
EMPOWER-Lung 1: Phase 3 first-line (1L) cemiplimab monotherapy vs platinum-doublet chemotherapy (chemo) in advanced non-small cell lung cancer (NSCLC) with programmed cell death-ligand 1 (PD-L1) ≥50% |
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196 |
Final overall survival (OS) analysis of PROfound: Olaparib vs physician’s choice of enzalutamide or abiraterone in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) and homol... |
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197 |
HR+/HER2- Breast Cancer ESMO 2020 Insights |
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198 |
PROfound Phase III trial results presented at ESMO established proven clinical activity of Lynparza (olaparib) in men with metastatic castration-resistant prostate cancer (mCRPC) with BRCA1/2 or ATM g... |
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199 |
Highlights in Urothelial Carcinoma- ESMO 2020 |
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200 |
ESMO 2020: Best of GI Cancers |
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201 |
COSMIC-021: Another exceptional findings by Exelixis after the success of CheckMate -9ER study results |
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202 |
ESMO 2020 – Ovarian Cancer Highlights |
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203 |
ASCO 2021 Preview - Showstoppers in Gastric Cancers |
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204 |
Amgen and Mirati – Leading Players With High Hopes for the Undruggable KRAS Mutation? |
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205 |
We Have Got You Covered – Major Data Readouts at ASCO 2021 Annual Meeting |
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206 |
ASC0 2021 Preview: Opdivo Boosting Relatlimab (LAG-3 Immunotherapy) Expected to Steal the Show? |
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207 |
Triumph of Trop-2 in Antibody-Drug Conjugate (ADC) Space |
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208 |
ASCO 2021 – MAGE-A4: Expectations from one of the most promising target in Oncology |
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209 |
ASCO 2021-OlympiA Trial: Label Expansion of Lynparza Could Open New Commercial Opportunities |
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210 |
Antibody Drug Conjugates Market Expansion: Steady Foothold in Cancer Treatment Through Significant Pacts |
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211 |
Novartis’ Phase III VISION Study: Radio-ligand Therapy Heading for Regulatory Approval |
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212 |
Day 1: ASCO 2021 Bladder Cancer Highlights |
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213 |
Day 1: ASCO 2021 Cholangiocarcinoma Highlights |
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214 |
Day 1 Highlights from Renal Cell Carcinoma (RCC) – ASCO 2021 |
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215 |
Day 1 Highlights in Sarcoma - ASCO 2021 |
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216 |
Day 1- ASCO 2021: Esophageal-Squamous Cell Carcinoma Highlights |
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217 |
Day 1 Highlights in Breast Cancer- ASCO 2021 (Local/Regional/Adjuvant) |
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218 |
Day 1 Highlights in Pancreatic Cancer- ASCO 2021 |
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219 |
Day 1 Highlights from Lung cancer - ASCO 2021 |
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220 |
Day 1 Highlights from Hematological cancer - ASCO 2021 |
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221 |
Day 2 Highlights in Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer- ASCO 2021 |
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222 |
Day 1-2 Highlights from Head and Neck Cancer (HNSCC) – ASCO 2021 |
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223 |
Day 1-2 ASCO 2021 Colorectal Cancer Highlights |
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224 |
Day 2 Highlights in Breast Cancer- ASCO 2021 |
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225 |
Day 2 Highlights from Hematological cancer – ASCO 2021 |
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226 |
Day 3 Nasopharyngeal Carcinoma Highlights ASCO21 |
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227 |
Day 3 Glioblastoma Multiforme (GBM) - ASCO 2021 Highlights |
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228 |
Day 3 Highlights from Lung cancer - ASCO 2021 |
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229 |
Day 3 RCC Highlights ASCO 2021 |
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230 |
ASCO 2021: Spotlight on Major Abstract in the Melanoma Segment |
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231 |
Day 4 Highlights from Prostate Cancer - ASCO 2021 |
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232 |
Day 4 Highlights from Hematological Cancers - ASCO 2021 |
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233 |
Day 4 Highlights-Gynecological Cancer- ASCO 2021 |
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234 |
Day 4- Nasopharyngeal cancer (NPC) Highlights: ASCO 2021 |
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235 |
Day 4 - Colorectal Cancer ASCO 2021 Highlights |
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236 |
Thyroid Cancer Highlights - ASCO 2021 |
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237 |
Highlights from Melanoma - ASCO 2021 |
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238 |
ESMO 2021 Preview: Margenza—a breast cancer drug—sets its niche in HER2 positive Gastric Cancer Space |
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239 |
ESMO 2021 Preview: Lilly and Innovent’s Sintilimab all set to present its high phase results in Esophageal Squamous Cell Cancer and Gastroesophageal Adenocarcinoma |
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240 |
Cheers to new headways in Oncology: Are you all ready for ESMO 2021 Annual Meeting? |
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241 |
ESMO 2021 Preview: Merck now Moving Ahead with Welireg and Cabozantinib Combination in Advanced ccRCC, Post-Welireg’s Speedy Approval in VHL-associated RCC |
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242 |
KRAS Players in ESMO 2021 – Mirati’s Adagrasib expected to Knockout Amgen’s much-hyped Lumakras in Colorectal Cancer: Can Toxicity Issues Ruin Mirati’s Plan? |
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243 |
ESMO 2021 Preview: Daiichi and AstraZeneca’s Antibody Drug Conjugate (ADC) in advanced NSCLC |
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244 |
ESMO 2021 Preview: Keytruda, already approved as a second-line treatment in Cervical Cancer, now eyeing first line setting |
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245 |
Abstract LBA1: DS-8201– keeping up with a continuous need for newer options and better outcomes for Breast Cancer patients |
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246 |
Bristol Myers Squibb to disclose data on Checkmate-651 trial evaluating Opdivo and Yervoy combination in frontline SCCHN after the regimen surprisingly fails to meet the primary endpoint |
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247 |
Merck to present overall survival results from KEYNOTE-355 in frontline Triple-Negative Breast Cancer to further support accelerated approval received in late 2020 |
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248 |
Evolving Landscape in First-Line HER2+ gastric cancer and gastro esophageal junction (GEJ) cancer |
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249 |
ESMO 2021: Leap Therapeutics flags the potential in advanced first-line Gastroesophageal adenocarcinoma (GEA) |
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|
250 |
ESMO 2021: Promising results of Ayala Pharma’s AL101 in Phase II ACCURACY trial for a rare form of cancer, Adenoid Cystic Carcinoma (ACC) |
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251 |
ESMO 2021: Gritstone to advance its Neo-antigen Immunotherapy in Phase II/III metastatic, microsatellite-stable (MSS)-Colorectal Cancer (CC) |
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252 |
ESMO 2021 Highlights: Sneak peek into some early phase results of Lung, Pancreatic, Prostate Cancer and others |
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253 |
ESMO 2021: Merck provides first glimpse of combination activity of belzutifan and cabozantinib in advanced clear cell renal cell carcinoma (ccRCC). |
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254 |
Merck’s Keytruda already carrying cervical cancer label in second-line, now spells a win in front-line setting with or without Avastin |
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255 |
ZENITH20 (LBA46) Phase II trial shows positive results with Poziotinib in treatment-naïve NSCLC harboring HER2 exon 20 mutations |
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256 |
ESMO 2021 Lung Cancer Highlights: Onboarding of Libtayo-Chemotherapy combo in first-line NSCLC. Should Merck worry? |
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257 |
Glad tidings for the Chinese Biopharmaceuticals in the Gastro-intestinal (GI) cancer |
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258 |
ESMO 2021: Post Tivdak’s successful approval in second line cervical cancer, the ADC now heading towards first-line setting as combination regimen |
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259 |
ESMO 2021: Daiichi and AstraZeneca’s Antibody Drug Conjugates (ADCs) in early phase trials, post Enhertu’s outstanding success in breast cancer |
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|
260 |
BMS’ LAG-3 and PD-1 inhibitor combo all set to fulfill high hopes in melanoma, post receiving priority review by the FDA |
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261 |
Already approved as an adjuvant therapy in late stage melanoma, Merck’s Keytruda is now eyeing completely resected high-risk stage II melanoma patients (KEYNOTE-716) |
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|
262 |
Exelixis excited to receive Cabometyx’s approval in radioiodine-refractory differentiated thyroid cancer (DTC) |
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263 |
ASCO 2022: A Quick preview of Late-Breaking Abstracts (LBA) on Lung Cancer. Let’s not miss it! |
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264 |
ASCO 2022 Preview Content for Breast Cancer |
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265 |
ASCO 2022 Preview: Prostate Cancer |
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266 |
ASCO 2022 Preview: Follicular Lymphoma |
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267 |
ASCO 2022: A quick preview of key abstract on melanoma. Let’s not miss it! |
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268 |
ASCO 2022: A Quick preview on Diffuse large B-cell lymphoma (DLBCL) |
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269 |
ASCO 2022 PREVIEW: GYNECOLOGIC CANCER |
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|
270 |
Cullinan Oncology’s CLN-081 demonstrates encouraging response in NSCLC patients with EGFR Exon 20 Insertion Mutations. |
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|
271 |
Immutep's next-generation immunotherapy performs well in first-line NSCLC, offering some relief following the recent failure of the novel anti-TIGIT in lung cancer. |
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272 |
Mirati’s Adagrasib overthrows Amgen’s Sotorasib and yielded a response rate of 43% in KRAS G12C mutation mNSCLC. Do first-mover advantage and safety give an edge to Sotorasib? |
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273 |
Exelixis’ flagship product Cabozantinib demonstrated an ORR of 54% with 91% clinical benefit in Head and Neck Squamous Cell Carcinoma |
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274 |
Roche’s Glofitamab, a CD20xCD3 bispecific mab, shows durable responses in R/R DLBCL in a pivotal phase II trial. Can Epcoritamab beat the CR rate of 39%? |
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|
275 |
Braftovi shows a higher response rate in a triplet combination after adding Opdivo. Shifting focus towards microsatellite stable metastatic colorectal cancer (MSS CRC) patients. |
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276 |
Closely watched Janssen and Legend Biotech's CAR-T cell therapy demonstrated durable responses in the earlier setting of Multiple Myeloma: Updated findings from the CARTITUDE-2 trial. |
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|
277 |
Genmab/Abbvie’s Epcoritamab achieves a 100% response rate in patients with R/R follicular lymphoma (FL). Could safety issues be a concern? |
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|
278 |
Gilead in trouble waters as Trodelvy shows below par response in 3L+ HR+/HER2- Breast Cancer Setting. Likelihood of a delayed launch and reduced market share? |
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|
279 |
Daiichi’s Patritumab, its third ADC making headway in HER3 expressing metastatic Breast Cancer |
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|
280 |
Enhertu carving out a new space for itself in HER2 low patients. A major-label expansion is likely on the way. |
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|
281 |
Yet another failure in treating Small-Cell Lung Cancer as Roche's much-anticipated anti-TIGIT immunotherapy fails in Phase III |
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282 |
Consistent results across all sub-groups seen in the newly launched first in class LAG-3 combination drug Opdualag |
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283 |
Encouraging results of nivolumab + bevacizumab + FOLFOXIRI in patients with RAS/BRAF mutations as a 1st Line treatment option, Opportunity for BMS for further expanding its blockbuster label for CRC p... |
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284 |
Merus’ Zenocutuzumab, a HER2-HER3 Bispecific Antibody, Successfully Targets NRG1 Fusions in Lung and Pancreatic Cancer |
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|
285 |
Teclistamab, a soon-to-be-approved bispecific antibody, demonstrates its promise in Multiple Myeloma during ASCO 2022. |
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|
286 |
Can Breyanzi be a hit CAR-T in second-line treatment after failing in the first-line setting for the patients with R/R Large B-cell lymphoma (LBCL)? |
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|
287 |
The PROs further support Durvalumab + Chemo in becoming the new standard of care in 1st Line Advanced Biliary Tract Cancer, patients with high treatment unmet needs. |
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288 |
Takeda’s flagship product panitumumab (PAN) + mFOLFOX6 versus bevacizumab (BEV) + mFOLFOX6 demonstrated better outcomes in primary endpoints for the Left-sided tumor population in metastatic colorecta... |
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289 |
Making way for immunotherapy in the GI cancers, Durvalumab to become the new standard of care for advanced biliary tract cancers |
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|
290 |
With modest efficacy, Neratinib continues to be a potential treatment option for HER2+ive biliary tract cancers. Puma Biotech to continue its search for more effective combination therapies. |
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291 |
Is there enough opportunity in the competitive therapeutic landscape of Multiple Myeloma for new CAR-T cell therapies? Let's have a look at the promising results of early-stage CAR-T cell therapy pres... |
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292 |
AbbVie’s telisotuzumab vedotin (Teliso-V) demonstrated encouraging responses in c-MET NSCLC patients who progressed on previous treatments. |
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|
293 |
Daiichi’s novel HER3 ADC has shown to have a spark in HER3 NSCLC, post success in HER3 Breast Cancer trial. |
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294 |
Junshi’s domestic Toripalimab’s significant results in recurrent or metastatic HNSCC. CRL issued on Nasopharyngeal Carcinoma could prove to be a setback? |
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295 |
Sermonix’s Lasofoxifene, a potent oral SERM, emerges as a critical player in ESR1 mutated advanced HR+ breast cancer |
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296 |
Mimivax’s SurVaxM improves survival time in newly diagnosed glioblastoma. A ray of hope flickers in deadly cancer. |
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297 |
Novartis’s Tafinlar and Mekinist’s combo might receive a first-mover advantage in BRAF mutated Low-grade glioma. |
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|
298 |
Is Paxalisib better than Temozolomide in the first-line setting? Approval seems quite challenging, though. |
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|
299 |
With the emergence of Next-generation SERDs, Sanofi might hit the mark; however, competition seems tough |
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300 |
Elranatamab exhibits a 60.6% ORR and a tolerable safety profile, according to new results from a planned interim analysis of the Phase II MagnetisMM-3 registration-enabling study. |
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301 |
Sanofi’s ADC is targeting CEACAM5 in patients with NSCLC. CEACAM5 is expressed in 20% of patients with NSCLC adenocarcinoma. |
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302 |
Performance of Veru Pharma’s Sabizabulin in Phase I/II mCRPC trial. Phase III VERACITY trial has already commenced. |
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303 |
Is GSK's Jemperli giving hope that cancer can be cured? 100% Response rate is unbelievable. |
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304 |
CEL-SCI Corporation presents first of its kind results for lower-risk advanced primary SCCHN population in 25+ years through its Phase III IT-MATTERS study. |
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305 |
Rocky road for Next-generation SERDs and Dominance of Verzenio in Adjuvant Setting: ER+/HER2− Early Stage Breast Cancer Insights |
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306 |
ESMO 2022 Preview: Metastatic Castration Resistant Prostate Cancer (mCRPC) |
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307 |
Early stage results of fianlimab, a human lymphocyte activation gene-3 (LAG-3) monoclonal antibody, in combination with cemiplimab in advanced melanoma |
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|
308 |
AmMax Bio’s AMB-05X shows an optimal balance of safety and efficay in TSGCT patients |
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|
309 |
Derazantinib in intrahepatic cholangiocarcinoma (iCCA) patients with FGFR2 mutations. |
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|
310 |
Already established combination in refractory mCRC patients to show results in the front-line patients to capture market share |
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311 |
Do tucatinib and trastuzumab have the potential to get the first mover advantage in HER2 positive mCRC? |
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|
312 |
Can fruquintinib prove to be more beneficial than the best supportive care in colorectal cancer? |
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313 |
AstraZeneca’s Triplet regimen (durvalumab + Olaparib + Bevacizumab) elicits excellent efficacy profile than doublet (olaparib plus durvalumab) in non gBRCA mutated (wild type), platinum-sensitive ovar... |
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314 |
Clinical study evaluating intermittent relacorilant with nab-paclitaxel in pretreated ovarian cancer |
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315 |
Postmarking clinical assessment of rucaparib vs. chemotherapy in advanced, relapsed patients with deleterious BRCA1/2 mutation in ovarian cancer |
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316 |
Extended follow-up results of Phase I/II study of DS-7300 (B7-H3 DXd antibody-drug conjugate [ADC]) in patients with advanced solid tumors (Lung Cancer, Esophageal Cancer, and Prostate Cancer) |
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317 |
Updated efficacy and safety of adagrasib (MRTX849) with or without cetuximab in patients with advanced colorectal cancer (CRC) harboring a KRASG12C mutation from the KRYSTAL-1 study |
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318 |
Amgen is attempting to expand into the CRC market with a cocktail of LUMAKRAS and VECTIBIX, however prior evidence indicates liver toxicity signals in Lung Cancer |
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319 |
Beyond Adagrasib and Lumakras, Roche's GDC-6036's phase I data are also scheduled to be presented at ESMO 2022. |
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320 |
Interim analysis of Phase III trial of Dalpiciclib plus letrozole or anastrozole as first-line treatment for HR+/HER2- advanced breast cancer (DAWNA-2) |
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321 |
Verzenio, an Eli Lilly CDK4/6 inhibitor, missed the statistical significance in the second interim overall survival analysis, but exhibited a favorable trend; all eyes are now on the final OS analysis... |
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322 |
Data from the planned second interim overall survival (OS) analysis further support Trodelvy (sacituzumab govitecan) in HR+/HER2– metastatic breast cancer |
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323 |
Confirmatory clinical OS results raising questions about the use of rucaparib in advanced Ovarian Cancer |
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324 |
Safety and efficacy results for Phase III trial of a dual anti-HER2 regimen of pyrotinib plus trastuzumab and docetaxel compared with placebo plus trastuzumab and docetaxel in untreated HER2-positive... |
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325 |
The combination of nivolumab with or without ipilimumab in R/M cervical cancer showed encouraging safety and efficacy results |
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326 |
Efficacy results from Phase II (FIDES-01) study with FGFR2F or FGFRMA patients with advanced iCCA with A, ≥1 prior chemotherapy |
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327 |
A Groundbreaking Study in Head and Neck Cancer to Improve Cure Rate by Adding new Treatment to SoC |
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328 |
Talimogene laherparepvec (T-VEC) as neoadjuvant treatment plus surgery vs immediate surgery in patients with resectable stage IVM1a melanoma |
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329 |
Naporafenib (LXH-254) combinations prove to exhibit favorable efficacy with a tolerable safety profile in NRAS-Mutant Unresectable/Metastatic Melanoma |
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330 |
Clinical efficacy and safety analysis update of intermittent relacorilant with nab-paclitaxel in heavily pretreated ovarian cancer patients |
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331 |
Cemiplimab in comparison with Investigator’s choice (IC) of chemotherapy in recurrent/metastatic cervical carcinoma |
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332 |
AstraZeneca’s Triplet regimen (durvalumab + Olaparib + Bevacizumab) bested over olaparib plus durvalumab doublet regimen in critical clinical profile evaluation in ovarian cancer |
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333 |
Adjuvant setting in RCC is a hard nut to crack, nivolumab + ipilimumab combo fails, whereas Keytruda leads |
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334 |
Trastuzumab Deruxtecan (Enhertu), the first US FDA-authorized HER2-directed treatment, produces clinically significant tumor response in patients with HER2m NSCLC in the Phase II DESTINY-Lung02 study |
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335 |
MEDI5752 plus chemotherapy doubled the duration of response among patients with treatment-naïve non-squamous NSCLC, according to findings from a phase Ib/II study |
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336 |
The Keynote-412 trial displays statistically insignificant results for Pembrolizumab plus CRT in locally advanced head and neck squamous cell carcinoma |
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337 |
Closely watched Lynparza, the first PARP inhibitor to enter the first-line metastatic castration-resistant Prostate Cancer (mCRPC) setting demonstrated superior clinical benefit over abiraterone alone |
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338 |
Triplet combination of tremelimumab + durvalumab + chemotherapy (T + D + CT) generated long-term overall survival (OS) benefit in frontline patients with metastatic NSCLC |
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339 |
Preliminary Phase II results of the CYPIDES study of ODM-208 in metastatic castration-resistant prostate (mCRPC) cancer patients |
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340 |
Initial results from the INSIGHT 2 study evaluating Tepotinib plus Osimertinib for EGFRm NSCLC with MET amplification (METamp) after progression on first-line (1L) osimertinib |
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341 |
Results from the randomized Phase II study of amcenestrant versus endocrine treatment of physician’s choice in patients with endocrine-resistant ER+/HER2− advanced breast cancer (AMEERA-3) |
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342 |
Already established combination in refractory mCRC patients to show results in the front-line patients to capture market share |
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343 |
Data from Phase III CodeBreak200 study showed superior PFS of Lumakras over docetaxel in previously treated non-small cell lung cancer (NSCLC) patients |
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344 |
A promising option for refractory patients expressing HER2+ tucatinib and trastuzumab have the potential to get the first mover advantage in mCRC |
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345 |
FRESCO-2 is a global Phase III study evaluating the safety and efficacy of fruquintinib in heavily pretreated mCRC patients |
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346 |
The clinical results of the DeFi trial of nirogacestat excels in adults with progressing desmoid tumors |
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347 |
Initial Findings from the Phase II/III Trial of AL102 for Desmoid Tumor treatment (DT) |
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348 |
Phase II Study of Belzutifan plus Cabozantinib as First-line Treatment of Advanced Renal Cell Carcinoma (RCC): Cohort 1 of LITESPARK-003 |
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349 |
ASCO 2023 PREVIEW CONTENT FOR BREAST CANCER: GRIPPING INSIGHTS INTO BREAST CANCER |
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ASCO 2023 PREVIEW CONTENT FOR NON-SMALL CELL LUNG CANCER (NSCLC) |
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351 |
ASCO 2023: A Quick preview of Late-Breaking Abstracts (LBA) and Late Phase abstracts on Head and Neck Cancer |
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352 |
Will the DESTINY-PanTumor02 trial serve to reinforce the potential of ENHERTU in treating a range of HER2-expressing cancers? |
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353 |
Nivolumab plus chemotherapy as a postoperative adjuvant therapy for stage III G/GEJ Cancer fell short of meeting the primary endpoint. However, it stimulates contemplation and prompts deeper reflectio... |
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354 |
IMerge: Promising Results of a Phase III Study Show Imetelstat's Potential in Transfusion-Dependent Non-del (5q) Lower-Risk Myelodysplastic Syndromes |
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355 |
Novartis unveils groundbreaking results from the pivotal Phase III NATALEE trial in early breast cancer patients |
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356 |
FELIX Study Validates Impressive Product Profile of Obe-cel: Efficacy and Safety in Perfect Harmony |
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357 |
Can REBLOZYL become a potential new first-line standard of care (SoC) for transfusion-dependent, lower-risk myelodysplastic syndromes? |
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358 |
A first-in-human study of CD123 NK Cell Engager SAR443579 in relapsed or refractory acute myeloid leukemia, B-cell acute lymphoblastic leukemia or high risk-myelodysplasia |
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359 |
Elranatamab Sparks Remarkable Responses in Relapsed/Refractory Myeloma Patients Following BCMA Therapy |
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360 |
Potent Responses Observed in Relapsed/Refractory Multiple Myeloma with Talquetamab Plus Daratumumab Combination Therapy |
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361 |
Janssen's Dual Bispecific Combination Study Achieves Unprecedented 96% Overall Response Rate in Relapsed or Refractory Multiple Myeloma Patients |
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362 |
Pfizer revealed the first-in-human data of potent and innovative CDK2-selective inhibitor PF-07104091 in advanced solid tumors, enriched for CDK4/6 inhibitor resistant HR+/HER2- breast cancer |
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363 |
Next-Gen CDK4-Selective Inhibitor PF-07220060 shines in first-in-human Phase I/IIa study, unveiling impressive results for advanced solid tumors enriched with HR+ HER2- mBC patients who experienced pr... |
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364 |
Improved outcomes in advanced ovarian cancer: LYNPARZA and IMFINZI combination reduces disease progression risk by 37% in DUO-O Phase III trial for patients without tumor BRCA mutations |
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365 |
BCMA/CD19 dual-targeting GC012F demonstrates highly promising activity in RRMM including high-risk patients and heavily pretreated patients with prior exposure to anti-38 mAb, PI, IMIDs |
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366 |
Luveltamab Tazevibulin provides significant clinical benefit for ovarian cancer patients, regardless of the varying levels of FolRα-expression heterogeneity |
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367 |
Jazz Pharmaceuticals and Zymeworks Present Positive Pivotal Phase IIb Trial Data of HERIZON-BTC-01 study Evaluating Zanidatamab in HER2-Amplified Biliary Tract Cancers |
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368 |
Oncolytics unveils groundbreaking findings from BRACELET-1 (PrE0113) trial, harnessing inflammatory phenotype in metastatic HR+/HER2- breast cancer with pelareorep, paclitaxel, and avelumab combinatio... |
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369 |
Junshi Biosciences revealed the impressive findings from the Phase III trial of toripalimab versus placebo, in combination with nab-P for patients with metastatic or recurrent TNBC |
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370 |
Ipsen presents the updated OS (overall survival) data for NALIRIFOX compared to Gem+NabP as a first-line therapy in patients with mPDAC. |
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371 |
Elicio Therapeutics shared encouraging interim findings from the AMPLIFY-201 –Phase I trial of therapeutic cancer immunotherapy. |
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372 |
ESR1 ER+/HER2- metastatic breast cancer market to witness the entry of a SERM in pretreated patients |
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373 |
Intracranial Efficacy of Sotorasib vs. Docetaxel in KRAS G12C-Mutated NSCLC: Insights from a Phase III Trial (Abstract # LBA9016) |
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374 |
ELAHERE results from MIRASOL recognized as transformative for the treatment of FRα-positive platinum-resistant ovarian cancer |
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375 |
AstraZeneca demonstrated the significant findings from the SERENA-2 Phase II trial of camizestrant versus fulvestrant |
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376 |
Linvoseltamab demonstrates high response rate and manageable toxicity in pretreated myeloma patients |
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377 |
A reduced dosage of Trastuzumab Deruxtecan demonstrates anti-tumor effectiveness in patients with HER2-positive mCRC |
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378 |
Alaunos Therapeutics presented early data from their Phase I study on Sleeping Beauty TCR-T cells targeting shared KRAS and TP53 mutations in solid tumors, showing promising safety and efficacy. |
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379 |
Kelun Pharma’s TROP2-targeting ADC shows early signs of potential in NSCLC patients |
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380 |
Roche presented the promising findings from the expansion stage of an ongoing Phase Ib study of glofitamab + Pola-R-CHP in patients with previously untreated diffuse large B-cell lymphoma (DLBCL) |
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381 |
Radiation Therapy Combined with TLR Agonists Like BDB001 and Atezolizumab Displays Enhanced Anti-Tumor Immunity With Promising DCR. |
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382 |
Phase 3 THOR Study: BALVERSA Outperforms Chemotherapy, Resulting in Over Four-Month Improvement in Median Overall Survival in Cohort 1 Patients |
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383 |
Vorasidenib Significantly Delays Disease Progression in Grade II IDH-Mutated Glioma |
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384 |
Promising Results from Phase I Clinical Trial of Investigational Agent ABBV-011 |
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385 |
AstraZeneca’s rilvegostomig, a TIGIT and PD-1 bispecific, offers hope for advanced pd-l1+ NSCLC after prior treatment resistance. |
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386 |
Janssen’s Talquetamab Shows Durable Responses in Heavily Pretreated Multiple Myeloma |
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387 |
Promising early Phase II results of Merck’s zilovertamab vedotin demonstrate efficacy against relapsed or refractory DLBCL |
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388 |
Gilead Sciences unveiled the striking results of Phase III ZUMA-7 study, highlighting YESCARTA CAR T-cell therapy's superiority over standard of care in initial treatment for curative Setting in R/R L... |
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389 |
Immutep Presents the Final Results from TACTI-002 Part C Study, Showing Encouraging Results in Second-line HNSCC Patients |
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390 |
Genfleet Therapeutics Presented the Updated Clinical Findings on GFH018 and Toripalimab Used in Combination for the Advanced Solid Tumor Patients |
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391 |
Toripalimab in combination with gemcitabine-cisplatin chemotherapy demonstrates significant improvement in the overall survival and progression-free survival |
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392 |
Pfizer revealed the promising Phase III Results from TALAPRO-2 study, paving the way for breakthrough treatment in gene-mutated mCRPC |
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393 |
Roche’s Atezolizumab and Exelixis’s Cabozantinib Combination Yields No Added Benefit in Second-Line Advanced Renal Cell Carcinoma |
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394 |
Impressive ORR of 37.1%: ENHERTU by AstraZeneca and Daiichi Sankyo Shines in DESTINY-PanTumor02 Phase II Trial |
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395 |
GenEros released encouraging findings from the Phase I clinical trial of GEC255, demonstrating its potential in treating advanced non-small cell lung cancer (NSCLC) patients who have the KRAS G12C mut... |
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396 |
BeiGene’s ROSEWOOD Study Reveals Strong Efficacy and Safety of Zanubrutinib plus Obinutuzumab in Heavily Pretreated Relapsed/Refractory FL Patients |
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397 |
KEYTRUDA: Effective Treatment for R/R cHL and R/R PMBCL with Manageable Safety Profile |
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398 |
Qualigen Therapeutics presented findings from the preclinical studies of their novel Pan-KRAS inhibitors, demonstrating the impact on efficacy and resistance to AMG-510 and MRTX-1133 in pancreatic can... |
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399 |
InventisBio released encouraging findings from the Phase I/II clinical trial of D-1553, demonstrating its potential as a monotherapy or in combination for treating advanced colorectal cancer patients... |
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400 |
Erasca Announces Update on ERAS-007, an ERK Inhibitor, from HERKULES-3 Trial |
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401 |
CodeBreaK 101: Promising Safety and Efficacy of Sotorasib, Panitumumab, and FOLFIRI in Previously Treated KRAS G12C-Mutated Metastatic Colorectal Cancer |
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402 |
AFNT-211: Empowering TCR-T Therapy to Conquer KRAS G12V Mutated Solid Tumors with Enhanced FAS-41BB Activation |
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403 |
Encouraging Responses in Follicular Lymphoma with the Addition of Epcoritamab to Rituximab and Lenalidomide |
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404 |
Bristol Myers Squibb's BREYANZI Demonstrates Swift Responses and Impressive Undetectable MRD Rates in Relapsed/Refractory CLL/SLL |
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405 |
Disease Stabilization in 26.9% of all Patients was Observed After the Treatment with ISA101b (peltopepimut-S) and Cemiplimab in Patients with Advanced HPV16+ Oropharyngeal Cancer. |
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|
406 |
With a median PFS of 10.4 months, the Combination of PDS0101 and Pembrolizumab in Subjects with HPV16 + Recurrent and/or Metastatic HNSCC appears promising. |
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407 |
OPDIVO and AVD Combination Emerges as the New Standard Therapy for Advanced-Stage Hodgkin Lymphoma |
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408 |
Innovent Biologics has released the findings of the CONTINUUM trial, which provide support for utilizing the combination of sintilimab and chemoradiotherapy as the new recommended treatment option |
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409 |
Daiichi Sankyo and AstraZeneca's breakthrough combo yields promising tumor reduction in advanced lung cancer patients: TROPION-Lung02 Phase Ib trial |
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410 |
Dizal Pharmaceuticals unveiled the astounding results of sunvozertinib in Chinese NSCLC patients with EGFR Exon 20 insertion mutations, resistant to platinum-based chemotherapy |
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411 |
Golidocitinib Demonstrates Promising Tumor Responses in Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL). |
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412 |
With Well-established Safety and Efficacy, Darolutamide (ODM-201) can Address the Needs of Patients with Androgen Receptor-positive Salivary Gland Carcinoma. |
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413 |
Sichuan Baili Pharmaceutical Presents the Updated Results of the Phase II clinical studies Performed on Patients with Recurrent and Metastatic HNSCC |
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414 |
Enfortumab Vedotin Used as a Single Treatment Showed Encouraging Effectiveness with Meaningful Clinical Responses |
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415 |
Mitazalimab with mFOLFIRINOX as a Promising Treatment Option for Individuals with Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC). |
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416 |
CARVYKTI Outperforms Two Standard Treatments in Progression-Free Survival at 16-Month Median Follow-Up in Lenalidomide-refractory Multiple Myeloma Patients |
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417 |
Preliminary Data Reveals Favorable Safety and Promising Activity of IBI351 Monotherapy in KRASG12C Mutated Advanced Colorectal Cancer. |
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418 |
Novartis presented the promising efficacy and safety data of JDQ443 in KRAS G12C-mutated solid tumors including NSCLC (KontRASt-01) |
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