Advanced Ovarian Cancer Pipeline Insight
DelveInsight’s, “Advanced Ovarian Cancer - Pipeline Insight, 2023,” report provides comprehensive insights about 60+ companies and 70+ pipeline drugs in Advanced Ovarian Cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Advanced Ovarian Cancer Understanding
Advanced Ovarian Cancer: Overview
Advanced Ovarian Cancer means that the cancer has spread outside the ovary. It may have spread within the pelvis or abdomen, or further away to other parts of the body such as the lungs. Some women have Advanced Ovarian Cancer when they are first diagnosed, and treatment can cure their cancer. This depends on several factors, including the exact stage of the cancer. Chemotherapy, surgery and targeted cancer drugs are all treatments for Advanced Ovarian Cancer. Some women may have radiotherapy. Targeted cancer drugs can help the body to control the growth of cancer cells. Occasionally doctors suggest radiotherapy for Advanced Ovarian Cancer. Radiotherapy can shrink tumours and reduce symptoms.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Advanced Ovarian Cancer R&D. The therapies under development are focused on novel approaches to treat/improve Advanced Ovarian Cancer.
Advanced Ovarian Cancer Emerging Drugs Chapters
This segment of the Advanced Ovarian Cancer report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Advanced Ovarian Cancer Emerging Drugs
Oregovomab: OncoQuest
Oregovomab is a murine IgG against CA 125. Indirect immunization with oregovomab interacts with immune modulating properties of infused paclitaxel and carboplatin resulting in synergistic clinical benefit as observed in a phase 2 trial. In a randomized Phase 2 clinical trial of 97 patients, treatment with Oregovomab in combination with chemotherapy had demonstrated a highly statistically significant and clinically meaningful outcome for both progression-free and overall survival compared to standard of care chemotherapy (carboplatin and paclitaxel). The risk of progression and of death was reduced by more than 50% when compared to control arm, and safety data showed that oregovomab did not add incremental toxicity to the chemotherapy regimen. Currently, the drug is in Phase III stage of Clinical trial evaluation for the treatment of advanced ovarian cancer.
SC 10914: Jiangxi Qingfeng Pharmaceutical Co. Ltd.
SC10914 is a highly selective inhibitor of PARP enzymes, including PARP1 and PARP2. SC10914 has a similar structure with olaparib. Currently the drug is in Phase II stage of Clinical trial evaluation for the treatment of Advanced Ovarian Cancer.
Stenoparib: Allarity Therapeutics
Stenoparib (2X-121) is a unique, small molecule dual targeted inhibitor of Poly ADP-Ribose Polymerases (PARP 1 and 2) and telomerase maintenance enzymes (Tankyrase 1 and 2). Allarity exclusively in-licensed it (globally) from Eisai. Currently the drug is in Phase II stage of Clinical trial evaluation for the treatment of Advanced Ovarian Cancer.
Further product details are provided in the report……..
Advanced ovarian cancer: Therapeutic Assessment
This segment of the report provides insights about the different advanced ovarian cancer drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in Advanced ovarian cancer
There are approx. 60+ key companies which are developing the therapies for advanced ovarian cancer. The companies which have their advanced ovarian cancer drug candidates in the most advanced stage, i.e. phase III include, OncoQuest.
Phases
DelveInsight’s report covers around 70+ products under different phases of clinical development like
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
Route of Administration
Advanced ovarian cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Oral
- Parenteral
- Intravenous
- Subcutaneous
- Topical.
Molecule Type
Products have been categorized under various Molecule types such as
- Monoclonal Antibody
- Peptides
- Polymer
- Small molecule
- Gene therapy
Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Advanced Ovarian Cancer: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Advanced Ovarian Cancer therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Advanced Ovarian Cancer drugs.
Advanced Ovarian Cancer Report Insights
- Advanced Ovarian Cancer Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
Advanced Ovarian Cancer Report Assessment
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Key Questions
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Advanced Ovarian Cancer drugs?
- How many Advanced Ovarian Cancer drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Advanced Ovarian Cancer?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Advanced Ovarian Cancer therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Advanced Ovarian Cancer and their status?
- What are the key designations that have been granted to the emerging drugs?
Introduction
Executive Summary
Advanced ovarian cancer: Overview
- Causes
- Mechanism of Action
- Signs and Symptoms
- Diagnosis
- Disease Management
Pipeline Therapeutics
- Comparative Analysis
Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
Advanced ovarian cancer – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
- Advanced ovarian cancer companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Advanced ovarian cancer Collaboration Deals
- Company-Company Collaborations (Licensing / Partnering) Analysis
- Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
- Comparative Analysis
Oregovomab: OncoQuest
- Product Description
- Research and Development
- Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
- Comparative Analysis
EP0057: Ellipses Pharma
- Product Description
- Research and Development
- Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
- Comparative Analysis
DS-6000a: Daiichi Sankyo Company
- Product Description
- Research and Development
- Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
- Comparative Analysis
Drug name: Company name
- Product Description
- Research and Development
- Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
- Comparative Analysis
Advanced ovarian cancer Key Companies
Advanced ovarian cancer Key Products
Advanced ovarian cancer- Unmet Needs
Advanced ovarian cancer- Market Drivers and Barriers
Advanced ovarian cancer- Future Perspectives and Conclusion
Advanced ovarian cancer Analyst Views
Advanced ovarian cancer Key Companies
Appendix
List of Table
Table 1: Total Products for Advanced Ovarian Cancer
Table 2: Late Stage Products
Table 3: Mid Stage Products
Table 4: Early Stage Products
Table 5: Pre-clinical & Discovery Stage Products
Table 6: Assessment by Product Type
Table 7: Assessment by Stage and Product Type
Table 8: Assessment by Route of Administration
Table 9: Assessment by Stage and Route of Administration
Table 10: Assessment by Molecule Type
Table 11: Assessment by Stage and Molecule Type
Table 12: Inactive Products
List of Figures
Figure 1: Total Products for Advanced Ovarian Cancer
Figure 2: Late Stage Products
Figure 3: Mid Stage Products
Figure 4: Early Stage Products
Figure 5: Preclinical and Discovery Stage Products
Figure 6: Assessment by Product Type
Figure 7: Assessment by Stage and Product Type
Figure 8: Assessment by Route of Administration
Figure 9: Assessment by Stage and Route of Administration
Figure 10: Assessment by Molecule Type
Figure 11: Assessment by Stage and Molecule Type
Figure 12: Inactive Products
• OncoQuest
• Allarity Therapeutics
• AstraZeneca
• Jiangxi Qingfeng Pharmaceutical Co. Ltd.
• CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
• Ellipses Pharma
• Merck KGaA
• Pfizer
• Jiangsu HengRui Medicine Co., Ltd.
• Boehringer Ingelheim
• Impact Therapeutics, Inc.
• Glycotope
• Puma Biotechnology, Inc.
• Bayer
• Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
• Daiichi Sankyo, Inc.
• Astellas Pharma Inc