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Cytomegalovirus (CMV) Infections - Market Insight, Epidemiology and Market Forecast - 2028

Published Date : 2019
Pages : 275
Region : United States, Japan, EU4 & UK
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cytomegalovirus cmv infection market insight epidemiology and market forecast

DelveInsight's "Cytomegalovirus (CMV) Infections - Market Insight, Epidemiology and Market Forecast - 2028" report deliver an in-depth understanding of the disease, historical and forecasted epidemiology as well as the market trends of Cytomegalovirus (CMV) Infections in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

CMV affects young children mainly, but it is estimated that by age 30 in the United States, half of all adults are, or have been, infected. The virus can pass from an infected, pregnant mother to her child through the shared blood supply (umbilical cord).

Among healthy individuals, CMV infection usually causes no symptoms; however, when CMV is transmitted congenitally (congenital CMV or cCMV) it can cause severe sequel. Despite the relatively high prevalence of cCMV infections and potentially serious effects, many women are unfamiliar with the risk of cCMV.

 

Geography Covered

• The United States

• EU5 (Germany, France, Italy, Spain, and the United Kingdom)

• Japan

 

Study Period: 2017-2028

 

Cytomegalovirus (CMV) Infections - Disease Understanding and Treatment Algorithm

The DelveInsight’s Cytomegalovirus (CMV) Infection market report gives a thorough understanding of the Cytomegalovirus (CMV) Infection by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis, and treatment.

Cytomegalovirus (CMV) Infection Diagnosis

This segment of the report covers the detailed diagnostic methods or tests for Cytomegalovirus (CMV) Infection.

Cytomegalovirus (CMV) Infection Treatment

It covers the details of conventional and current medical therapies available in the Cytomegalovirus (CMV) Infection market for the treatment of the condition. It also provides Cytomegalovirus (CMV) Infection treatment algorithms and guidelines in the United States, Europe, and Japan.

According to DelveInsight, the total diagnosed cases of CMV were found out to be approximately 110,540 in the 7MM. The number of CMV cases in the 7MM is expected to increase during the study period of 2017-2028. In 7MM, Hematopoietic Stem Cell Transplants (allogeneic HSCT) patients is increasing throughout the study period (2017-2028). While, HIV patients is decreasing throughout the study period (2017-2018) due to the High Active Antiretroviral Therapy (HAART).

Cytomegalovirus (CMV) Infections Drug Chapters

This segment of the Cytomegalovirus (CMV) Infections report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. Currently, antiviral drugs are used for CMV infection following transplant procedures. The drugs include valganciclovir, ganciclovir, cidofovir, foscarnet, or a combination, etc. Recently, Prevymis (Letermovir) received FDA approval for the prevention of Human Cytomegalovirus (HCMV) infection in transplant patients.

There are two major strategies for CMV disease prevention after liver transplantation that includes preemptive therapy and antiviral prophylaxis. Before ART was widely available, daily use of oral ganciclovir (no longer marketed in the United States) for primary prophylaxis significantly reduced the incidence of CMV disease in a randomized, placebo-controlled trial.

The first-line options for therapy of CMV disease, are almost always intravenous ganciclovir or oral valganciclovir. Foscavir (FOS) is considered second-line therapy but is the preferred drug for patients who are failing GCV therapy due to viral resistance, or those who cannot be treated with GCV due to dose-limiting neutropenia or leucopenia. Another second-line therapy for CMV disease, cidofovir (Vistide, Gilead), is—like foscarnet—an inhibitor of the CMV DNA polymerase.

CMV Infection market is flooded with Generic products as the top-selling drugs have gone off-patent. Most recent gone off the patent drug was Valcyte, which lost its patent in 2013 and 2015 in the US and Europe, respectively.

 

Cytomegalovirus (CMV) Infections Market Outlook

According to DelveInsight, the market of Cytomegalovirus (CMV) Infections in 7MM was found to be approximately USD 1195.10 million in 2017. Cytomegalovirus (CMV) Infections market size in the United States accounted for approx. 68.16% of the total market in 2017.

Among the EU5 countries, in 2017, France had the highest market size with approximately USD 84.00 million, while Italy had the lowest market size for CMV Infection with approximately USD 47.00 million.

The market size of prophylactic and therapeutic CMV Infection in seven major markets was approximately USD 771.00 million and 423.00 million in 2017.

 

Cytomegalovirus (CMV) Infections Drugs Uptake

The dynamics of Cytomegalovirus Infection market is anticipated to change during the forecasted period owing to the expected launch of emerging therapies. There are many pipeline therapies under development for the prevention of Congenital Cytomegalovirus and treatment of Cytomegalovirus infection following transplant (allogeneic hematopoietic stem cell transplantation/Solid-organ transplantation). The therapies which are under development for the prophylaxis or treatment of CMV Infection are Maribavir (Shire), ATA230 (Atara Biotherapeutics), Viralym-M (ViraCyte), V160 (Merck Sharp and Dohme Corp), Cytotect-70 (BioTest, (EU5 only)) and Triplex (Helocyte).

 

Cytomegalovirus (CMV) Infections Report Insights

• Patient Population by Total diagnosed cases

• Infants born with Congenital CMV

• CMV Patients among Hematopoietic Stem Cell Transplants (HSCT)

• CMV Patients among Solid Organ Transplants (SOT)

• Refractory CMV Patients after HSCT/SOT

• CMV Retinitis among HIV Patients

• Therapeutic Approaches

• Pipeline Analysis

• Market Size and Trends

• Market Opportunities

• Impact of upcoming Therapies

 

Cytomegalovirus (CMV) Infections Report Key Strengths

• 10 Year Forecast

• 7MM Coverage

• Epidemiology Segmentation

• Drugs Uptake

• Highly Analyzed Market

• Key Cross Competition

 

Cytomegalovirus (CMV) Infections Report Assessment

• Current Treatment Practices

• Unmet Needs

• Detailed Pipeline Product Profiles

• Market Attractiveness

• Market Drivers and Barriers

 

Key Benefits

• This DelveInsight report will help to develop Business Strategies by understanding the trends shaping and driving Cytomegalovirus (CMV) Infections market

• Organize sales and marketing efforts by identifying the best opportunities for Cytomegalovirus (CMV) Infections market

• To understand the future market competition in the Cytomegalovirus (CMV) Infections market.

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