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Cytomegalovirus Cmv Infection Pipeline Insight

DelveInsight’s, “Cytomegalovirus (CMV) Infection - Pipeline Insight, 2021,” report provides comprehensive insights about 20+ companies and 20+ pipeline drugs in Cytomegalovirus (CMV) Infection pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

  • Global coverage

Cytomegalovirus (CMV) Infection Understanding

Cytomegalovirus (CMV) Infection: Overview

Cytomegalovirus (CMV) infection is caused by the human cytomegaloviruses. These are a subgroup of infective agents who belongs to the Herpesviridae family and is closely related to the herpes group of viruses. Cytomegalovirus (CMV) Infection is a common herpesvirus infection with a wide range of symptoms including fever and fatigue (resembling infectious mononucleosis), swollen glands, pneumonia with hypoxemia, or low blood oxygen, and sore throat. CMV spreads by direct contact of body fluids, such as saliva, blood, urine, semen, vaginal fluids, congenital infection, and breast milk. Diagnosis of a CMV infection can be confirmed by detection of CMV-induced large inclusion bodies present in urine sediment. The currently available antivirals for CMV therapy works by inhibiting the viral DNA polymerase. The approved treatment includes: Ganciclovir, valganciclovir, cidofovir, and foscarnet, to treat diseases caused by CMV in immunocompromised patients.

"Cytomegalovirus (CMV) Infection - Pipeline Insight, 2021" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Cytomegalovirus (CMV) Infection pipeline landscape is provided which includes the disease overview and Cytomegalovirus (CMV) Infection treatment guidelines. The assessment part of the report embraces, in depth Cytomegalovirus (CMV) Infection commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Cytomegalovirus (CMV) Infection collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Cytomegalovirus (CMV) Infection R&D. The therapies under development are focused on novel approaches to treat/improve Cytomegalovirus (CMV) Infection.

Cytomegalovirus (CMV) Infection Emerging Drugs Chapters

This segment of the Cytomegalovirus (CMV) Infection report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Cytomegalovirus (CMV) Infection Emerging Drugs

mRNA-1647: Moderna Therapeutics

mRNA-1647 is a vaccine combining six mRNAs in a single vial, which encode for two antigens located on the surface of CMV: five mRNAs encoding the subunits that form the membrane-bound pentamer complex and one mRNA encoding the full-length membrane-bound glycoprotein B (gB). The vaccine is in Phase II clinical studies for the treatment of CMV.

Maribavir: Takeda

TAK-620 (maribavir), is an investigational, orally bioavailable, ganciclovir kinase inhibitor based antiviral compound. The FDA has granted Maribavir Orphan Drug Designation for the treatment of clinically significant CMV viremia and disease in at-risk patients. The FDA has also granted maribavir Breakthrough Therapy Designation as a treatment for CMV infection and disease in transplant patients resistant or refractory to prior therapy. In May 2021, Takeda announced that the US Food & Drug Administration (FDA) had accepted a New Drug Application (NDA) for maribavir for the treatment of CMV infection in those that are refractory with or without resistance (R/R), in solid organ transplant (SOT) or hematopoietic cell transplant (HCT) recipients.

Further product details are provided in the report……..

Cytomegalovirus (CMV) Infection: Therapeutic Assessment

This segment of the report provides insights about the different Cytomegalovirus (CMV) Infection drugs segregated based on following parameters that define the scope of the report, such as:

  • Major Players in Cytomegalovirus (CMV) Infection

There are approx. 20+ key companies which are developing the therapies for Cytomegalovirus (CMV) Infection. The companies which have their Cytomegalovirus (CMV) Infection drug candidates in the most advanced stage, i.e. Preregistration include, Takeda.


DelveInsight’s report covers around 20+ products under different phases of clinical development like

  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration

Cytomegalovirus (CMV) Infection pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral
  • Parenteral
  • Intravitreal
  • Subretinal
  • Topical
  • Molecule Type

Products have been categorized under various Molecule types such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Cytomegalovirus (CMV) Infection: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Cytomegalovirus (CMV) Infection therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Cytomegalovirus (CMV) Infection drugs.

Cytomegalovirus (CMV) Infection Report Insights

  • Cytomegalovirus (CMV) Infection Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Cytomegalovirus (CMV) Infection Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

  • How many companies are developing Cytomegalovirus (CMV) Infection drugs?
  • How many Cytomegalovirus (CMV) Infection drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Cytomegalovirus (CMV) Infection?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Cytomegalovirus (CMV) Infection therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Cytomegalovirus (CMV) Infection and their status?
  • What are the key designations that have been granted to the emerging drugs?


Executive Summary

Cytomegalovirus (CMV) Infection: Overview

  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management

Pipeline Therapeutics

  • Comparative Analysis

Therapeutic Assessment

  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type

Cytomegalovirus (CMV) Infection – DelveInsight’s Analytical Perspective

Late Stage Products (Preregistration)

  • Comparative Analysis

Maribavir: Takeda

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Mid Stage Products (Phase II)

  • Comparative Analysis

V 160: Merck & Co

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Early Stage Products (Phase I)

  • Comparative Analysis

mRNA-1647: Moderna Therapeutics

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Preclinical/Discovery Stage Products

  • Comparative Analysis

Cytomegalovirus vaccine: SpyBiotech

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Inactive Products

  • Comparative Analysis

Cytomegalovirus (CMV) Infection Key Companies

Cytomegalovirus (CMV) Infection Key Products

Cytomegalovirus (CMV) Infection- Unmet Needs

Cytomegalovirus (CMV) Infection- Market Drivers and Barriers

Cytomegalovirus (CMV) Infection- Future Perspectives and Conclusion

Cytomegalovirus (CMV) Infection Analyst Views


List of Table

Table 1: Total Products for Cytomegalovirus (CMV) Infection

Table 2: Late Stage Products

Table 3: Mid Stage Products

Table 4: Early Stage Products

Table 5: Pre-clinical & Discovery Stage Products

Table 6: Assessment by Product Type

Table 7: Assessment by Stage and Product Type

Table 8: Assessment by Route of Administration

Table 9: Assessment by Stage and Route of Administration

Table 10: Assessment by Molecule Type

Table 11: Assessment by Stage and Molecule Type

Table 12: Inactive Products

List of Figures

Figure 1: Total Products for Cytomegalovirus (CMV) Infection

Figure 2: Late Stage Products                             

Figure 3: Mid Stage Products

Figure 4: Early Stage Products

Figure 5: Preclinical and Discovery Stage Products

Figure 6: Assessment by Product Type

Figure 7: Assessment by Stage and Product Type

Figure 8: Assessment by Route of Administration

Figure 9: Assessment by Stage and Route of Administration

Figure 10: Assessment by Molecule Type

Figure 11: Assessment by Stage and Molecule Type

Figure 12: Inactive Products   

• Moderna Therapeutics

• Takeda

• AlloVir

• SpyBiotech

• Trinomab Biotech

• Evrys Bio

• Merck & Co

• Biotest

• Stadius Biopharma

• Citranvi Biosciences

• Xyphos

• Orbis Biosciences

• Nobelpharma

• Hookipa Biotech

• AlphaVax, Inc.

• Trellis Bioscience

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