Gingival Recession Market

 

Key Highlights

 

• Sekino et al. (2020) found that the mean plaque score and gingival bleeding rate of the residents were 64 and 48%, respectively, and that the degree of attachment loss increased with age. In conclusion, it was stated that periodontal disease is still prevalent in the current Japanese population, even though some improvement occurred.

 

• The Gingival recession epidemiology is segmented as Total Prevalent Cases of Gingival recession, Age-specific prevalent cases of Gingival Recession, Gender-specific prevalent cases of Gingival Recession, Diagnosed and Treatable cases of Gingival Recession in the 7MM covering the United States, EU4 countries (Germany, France, Italy, Spain), the United Kingdom, and Japan from 2019 to 2032.

 

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DelveInsight’s “Gingival recession Market Insights, Epidemiology, and Market Forecast – 2032” report delivers an in-depth understanding of the Gingival recession, historical and forecasted epidemiology as well as the Gingival recession market trends in the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

 

The Gingival recession market report provides current treatment practices, emerging drugs, Gingival recession market share of the individual therapies, and current and forecasted Gingival recession market size from 2019 to 2032, segmented by seven major markets. The report also covers current Gingival recession treatment practices/algorithms and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.

 

Geography Covered

• The United States
• EU4 (Germany, France, Italy, Spain), and the United Kingdom
• Japan

 

Study period: 2019–2032

 

Gingival Recession Market Disease: Understanding and Treatment Algorithm

 

The DelveInsight’s Gingival recession market report gives a thorough understanding of Gingival recession by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis, and treatment. 

 

Gingival recession, also known as receding gums, is one of the most common esthetic concerns associated with the periodontal tissues. It is characterized by the displacement of the gingival margin apically from the cementoenamel junction, or CEJ, or from the former location of the CEJ in which restorations have distorted the location or appearance of the CEJ. Several classifications have been proposed in the literature to facilitate the diagnosis of gingival recessions. Miller (1985) proposed a classification system which is probably still the most widely used system for describing the gingival recession. Four types of recession defects were categorized as class I, class II, class III and class IV. 

 

Gingival recession is a very common dental problem; therefore, most people do not know they have gum recession as it occurs gradually. The first sign of gum recession is usually tooth sensitivity, or the patient may notice a tooth which looks longer than normal. Typically, a notch can be felt near the gum line as well.

 

Primary causes of gingival recession are low-level and long-lasting trauma, also known as chronic trauma. Other causes are chronic inflammatory periodontal disease, periodontal treatment, genetics, insufficient dental care, tobacco product consumption, and grinding and clenching of teeth. The consequences of these are poor aesthetics, gingival bleeding and plaque retention, hypersensitivity and risk of the development of root caries as root surfaces are exposed to oral environment and aid in the withholding of plaque. 

 

 Gingival recession Diagnosis

Receding gums are diagnosed by a dentist. A physical examination can indicate issues. A probe may also be used to measure gum pockets. A probe is a process that uses a small, painless ruler. According to the National Institute of Dental and Craniofacial Research, normal pocket sizes range between 1–3 millimeters. Anything larger is a sign of gum disease.

 

Gingival recession Treatment

Depending on the symptoms the patient exhibits, the diagnostic process is carried out. Treatment usually involves restorations, crowns, and veneers, construction of gingival mask, root conditioning, frenectomy and lastly surgical root coverage techniques.

 

Gingival recession Epidemiology 

The Gingival recession epidemiology section provides insights into historical and current Gingival recession patient pool and forecasted trends for seven individual major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Gingival recession report also provides the diagnosed patient pool, their trends and assumptions undertaken.

 

Key findings

 

• In a study conducted by Carlos et al (2018), 69.7% of subjects had ≥ 1 site with recession ≥ 1 mm, and 30.3% had ≥ 1 site with recession ≥ 3 mm. A total of 28.6% of teeth were affected by recession ≥ 1 mm, and 7.6% by recession ≥ 3 mm. The most frequently affected tooth types were first maxillary molars, first and second mandibular premolars, and the first maxillary premolar. Factors signify- cantly associated with recession ≥ 4 mm were: older age, male gender, lower income, former smoker, diabetes, and less frequent tooth brushing.

 

• A study by Sather (2014) assessed the recession descriptives by gender. Forty-four teeth were measured for the gingival recession in males, and 70 teeth were measured in females. Mean recession was higher in males than females (1.83mm ± 2.06mm vs. 1.73mm ± 1.28mm); however, this difference was not statistically significant (Mann-Whitney U Test, p = 0.33). Males showed a greater range of recession than females (0–6.72mm vs. 0–5.7mm, respectively).

 

• The prevalence of recession in the anterior zone in patients at the University of Santiago de Compostela (USC) dental faculty was 26%. The average age of the patients in this study was 53.35 years. Of the total patients with the gingival recession in the anterior zone, 57.7% were women (Lorenzo et al., 2019). 

 

• In a study published by the Journal of Dental Research, the Centers for Disease Control and Prevention (CDC) estimated that at 52.79% and 51.10% respectively, New Mexico and Hawaii had the United States’ highest prevalence of periodontitis, the advanced form of gum disease (American Academy of Periodontology, 2016).

 

• Sekino et al. (2020) found that the mean plaque score and gingival bleeding rate of the residents were 64 and 48%, respectively, and that the degree of attachment loss increased with age. In conclusion, it was stated that periodontal disease is still prevalent in the current Japanese population, even though some improvement occurred.

 

• The Gingival recession epidemiology is segmented as Total Prevalent Cases of Gingival recession, Age-specific prevalent cases of Gingival Recession, Gender-specific prevalent cases of Gingival Recession, Diagnosed and Treatable cases of Gingival Recession in the 7MM covering the United States, EU4 countries (Germany, France, Italy, Spain), the United Kingdom, and Japan from 2019 to 2032.

 

Country-wise Gingival recession Epidemiology

The epidemiology segment also provides the Gingival recession epidemiology data and findings across the United States, EU4 (Germany, France, Italy, Spain), the United Kingdom, and Japan.

 

Gingival recession Drug Chapters

The drug chapter segment of the Gingival recession report encloses the detailed analysis of Gingival recession marketed drugs and late-stage (Phase III and Phase II) Gingival recession pipeline drugs. It also helps understand the Gingival recession clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

 

Emerging Gingival Recession Drugs

 

The emerging landscape of Gingival Recession is not very prominent. Not many companies have indulged themselves in developing a novel treatment option. Markman Biologics Corporation recently announced the execution of a strategic agreement with The McGuire Institute as a principal investigators for an upcoming clinical trial on humans. The main objective of the trial which is being conducted is to evaluate clinical healing outcomes of microsurfaced cadaveric ADM (Markman Biologics) used in sites with < 1 mm of attached gingiva requiring soft tissue grafting without root coverage as compared to control cadaveric ADM.

 

There are various institutes that are working on Gingival Recession by using Mesenchymal Stem Cells, and Ubiquinon (Coenzyme Q10) Application. Majorly companies are developing devices to address this condition.

 

Gingival recession Market Outlook

 

Gingival recession can have several causes. The treatment of receding gums mainly depends upon the cause. Gum recession can not be reversed; this means receded gum tissue would not grow back. However, one can keep the problem from getting poorer. If the gums become unattached from the tooth, it is important to treat gum recession. Otherwise, with the passage of time, this condition gets worse. 

 

If hard brushing or poor dental hygiene is the cause, it is recommended to talk to the dental hygienist about changing the brushing and flossing behaviors. An individual may need to have occasional deep cleaning treatments called “scaling and root planing” to treat gum recession. 

 

Mild gum recession can be treated by a professional deep cleaning in the affected area. During the deep cleaning, plaque and tartar are removed, and the exposed root area is smoothed over, making it more difficult for bacteria to attach itself. If deep cleaning is not sufficient to treat the condition, because of excess loss of bone and deep pockets, then receding gums surgery is required. In addition, an effective management and prevention program should help to improve patient awareness about gingival recession and to adopt adequate oral hygiene measures.

 

Open flap scaling and root planing: During this procedure, the dentist or periodontist (gum doctor) folds back the affected gum tissue, removes the harmful bacteria from the pockets, and then snugly secures the gum tissue in place over the tooth root, thus eliminating the pockets or reducing their size. The pedicle flap was the first periodontal plastic surgery procedure proposed in 1956 for root coverage. This procedure consists of the repositioning of the donor tissue from an area adjacent to the recession defect to cover the exposed root surface. Since the flap remains attached at the base, it retains its blood supply, facilitating the revascularisation with the recipient site. 

 

Pinhole surgical technique: Pinhole surgical technique (PST) is a relatively new treatment for mild to moderate receding gums. PST is a minimally invasive procedure that involves making a tiny hole in the gum tissue above the exposed tooth root. A dentist will insert a special tool into the hole to separate the gum from the tooth, and then they will stretch and reposition the gum back over the exposed tooth root.

 

Construction of Gingival Mask: Patients who have several teeth with recession may have unaesthetic appearance because of black triangles. In these cases, where a surgical procedure is not appropriate, silicone flexible gingival veneer or mask may be used.

 

Antibiotic treatments can be used either in combination with surgery and other therapies or alone, to reduce or temporarily eliminate the bacteria associated with gum disease or suppress the destruction of the tooth's attachment to the bone. Few commonly used antibiotic drugs are doxycycline and tetracycline,, as prescribed by the dentist.

 

Apart from these, one of the traditional ways to treat gum recession is through the use of gum grafting which has been a proven method to restore a healthy gum line, but this procedure requires cutting and stitching. It can be a painful process for our patients, and it can take several weeks to heal. 

 

Key findings

 

This section includes a glimpse of the Gingival recession market in 7MM.

 

The United States: Gingival recession Market Outlook

This section provides the total Gingival recession market size and market size by therapies in the United States.

 

EU4 and the UK Countries: Gingival recession Market Outlook

The total Gingival recession market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.

 

Japan: Gingival recession Market Outlook

The total Gingival recession market size and market size by therapies in Japan are also mentioned.

 

Gingival recession Drug Uptake

 

This section focuses on the rate of uptake of the potential drugs recently launched in the Gingival recession market or expected to get launched in the market during the study period 2019–2032. The analysis covers Gingival recession market uptake by drugs, patient uptake by therapies, and sales of each drug.  

 

This will help in understanding the Gingival recession drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on market share and size, which again will be useful in investigating factors important in the market uptake and in making financial and regulatory decisions.

 

Gingival recession Pipeline Development Activities

 

The report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Gingival recession’s key players involved in developing targeted therapeutics.

 

Gingival Recession Clinical Trial Development Activities

 

The Gingival recession clinical trial report covers detailed information on collaborations, acquisitions, and mergers, licensing patent details, and other information for Gingival recession emerging therapies.

 

Gingival recession Reimbursement Scenario

 

Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

 

KOL Views

 

To keep up with current epidemiology and market trends, we take KOLs and SMEs' opinions working in the Gingival recession domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies and treatment patterns along with Gingival recession market trends. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the market and the Gingival Recession unmet needs.

 

Competitive Intelligence Analysis

 

We perform competitive and market intelligence analysis of the Gingival recession market by using various competitive intelligence tools that include – SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.

 

Scope of the Gingival Recession Market Report

• Descriptive overview of Gingival recession, disease overview, patient journeys, treatment algorithms, diagnosis, and currently available therapies
• Comprehensive insight into the Gingival recession epidemiology and forecasts in the 7MM
• An all-inclusive account of both the current and emerging therapies for Gingival recession, along with the assessment of new therapies, expected to have an impact on the current treatment landscape
• Exhaustive analysis of the Gingival recession market; historical and forecasted covering drug outreach in the 7MM
• Detailed patient-based Gingival Recession market forecasting determines the trends shaping and driving the global Gingival recession market

 

Gingival Recession Market Report Highlights

• In the coming years, the gingival recession market is set to change due to the rising awareness of the disease and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
• The companies and academics are working to assess challenges and seek opportunities that could influence gingival recession R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition   
• Major players are involved in developing gingival recession therapies. The launch of emerging therapies will significantly impact the gingival recession market
• A better understanding of gingival recession pathogenesis will also contribute to the development of novel therapeutics for gingival recession
• Our in-depth analysis of the gingival recession pipeline assets across different stages of development (Phase III and Phase II), emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

 

Gingival Recession Market Report Insights

• Patient-Based Gingival Recession Market Forecasting 
• Therapeutic approaches
• Gingival recession pipeline analysis
• Gingival recession market size and trends
• Gingival recession market opportunities
• Impact of upcoming therapies

 

Gingival Recession Report Key Strengths

• 11 years forecast
• 7MM Coverage
• Gingival recession epidemiology segmentation
• Key cross competition
• KOL views
• Gingival recession drugs uptake

 

Gingival Recession Report Assessment

• Current treatment practices
• Gingival Recession Unmet needs
• Gingival recession pipeline product profiles
• Gingival recession market attractiveness

 

Key Questions

 

Gingival Recession Market Insights:

• What would be the Gingival recession market growth till 2032, and what will be the resultant market size in 2032?
•  What was the Gingival recession drug class share (in percentage) distribution in 2019, and how would it look in 2032?
• What would be the Gingival recession total market size and market size by therapies across the 7MM during the forecast period (2019–2032)?
• What are the key findings of the market across 7MM, and which country will have the largest Gingival recession market size during the forecast period (2019–2032)
• How would the unmet needs affect the Gingival recession market dynamics and subsequent analysis of the associated trends?

 

Gingival recession Epidemiology Insights:

• What are the disease risk, burden, and regional/ethnic differences of Gingival recession?
• What is the historical and forecasted Gingival recession patient pool in 7MM, and where can one observe the highest patient population and growth opportunities? 
• What are the key factors driving the epidemiology trends for seven major markets covering the United States, EU4 (Germany, Spain, France, Italy), the UK, and Japan?

 

Current Treatment Scenario, Gingival Recession Marketed Drugs, and Gingival Recession Emerging Therapies

• What are the current treatment guidelines and treatment options, in addition to approved therapies for Gingival recession in the US, Europe, and Japan?
• What are the key collaborations (Industry–Industry, Industry-Academia), mergers and acquisitions, and licensing activities related to Gingival recession therapies?
• What are the recent novel therapies, targets, mechanisms of action, and technologies being developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for Gingival recession and its status, along with the challenges faced?

 

Reasons to Buy

• The patient-based Gingival Recession market forecast analysis will help in developing business strategies by understanding trends shaping and driving the Gingival recession market
• Organize sales and marketing efforts by identifying the best opportunities for Gingival recession in the US, Europe (Germany, Spain, Italy, France), the United Kingdom, and Japan
• Identification of strong upcoming players in the market that will help devise strategies that will help in getting ahead of competitors