kyphoscoliosis epidemiology forecast

Key Highlights:

• Kyphoscoliosis is a complex spinal deformity characterized by an abnormal curvature of the spine in both the sagittal and coronal planes, often accompanied by axial rotation.
• Kyphoscoliosis is a spinal disorder that combines two conditions: scoliosis and kyphosis. Scoliosis results in an abnormal sideways curvature of the spine, while kyphosis leads to an exaggerated outward curve.
• In population-based studies, the overall prevalence of kyphoscoliosis is estimated to be approximately 1 in 1,000 individuals, although this varies with age and etiology.
• Kyphoscoliosis is multifactorial in origin, often depending on a patient’s age, genetic background, comorbidities, and functional status. For clinical clarity, etiologies are typically categorized as idiopathic, secondary (acquired or disease-related), congenital, or functional.
• This condition can occur at any age, including at birth. According to a case report about the condition, 80% of cases are idiopathic. This means there’s no known cause of the condition.
• Scheuermann disease, also known as juvenile kyphosis or juvenile discogenic disease, is a slowly progressive disorder of the spine most commonly affecting adolescents and involves the wedging of 3 or more adjacent vertebrae at an angle of more than 5 degrees.
• In the majority of hyperkyphosis cases in the elderly, approximately 60–70%, are not caused by underlying vertebral compression fractures but by other factors like degenerative disc disease, reduced back extensor muscle strength, and poor posture.

DelveInsight’s “Kyphoscoliosis – Epidemiology Forecast – 2034” report delivers an in-depth understanding of kyphoscoliosis, historical and forecasted epidemiology in the United States, EU4 (Germany, France, Italy, and Spain), and the United Kingdom, and Japan.

Geography Covered

• The United States
• EU4 (Germany, France, Italy, and Spain) and the United Kingdom
• Japan

Study Period: 2020–2034

Kyphoscoliosis Disease Understanding

Kyphoscoliosis Overview

Kyphoscoliosis is the abnormal curvature of the spine in two planes: The sagittal plane, which is the backward-to-forward angle, and the coronal plane, which is the side-to-side angle. It may also be associated with spinal axis rotation. Sideways deviation of the spine curvature is known as Scoliosis, and abnormal forward to backward rounding of the back is known as Kyphosis. The impact of these abnormal curvatures on the body depends upon the location, degree of curvature, spinal axis rotation, and severity.

Kyphoscoliosis Diagnosis

Kyphoscoliosis can be diagnosed based on medical history, physical examination, functional assessment, and diagnostic imaging scans.

• Medical history: A thorough medical history of the age of onset of the disease, appearance of changes, along with neurological and psychosocial impacts, is noted.
• Physical examination: It involves evaluation of spinal alignment, height, movements, degree of flexibility, reflexes, sensations, and muscle strength.
• Functional assessment: A walking test for 6 minutes or standing up from a sitting position helps in assessing the severity of the disease.
• Diagnostic imaging: X-rays may be taken to assess the degree of asymmetry, and MRI and bone mineral density scans may be recommended if additional investigations are required.

In severe cases, lung function tests such as Functional Residual Capacity (FRC) and Forced Vital Capacity (FVC) are carried out.

Further details related to country-based variations are provided in the report.

Kyphoscoliosis Epidemiology

The kyphoscoliosis epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by total diagnosed prevalent cases of kyphoscoliosis, age-specific prevalent cases of kyphoscoliosis, gender-specific prevalent cases of kyphoscoliosis, severity-specific prevalent cases of kyphoscoliosis, in the 7MM covering the United States, EU4 (Germany, France, Italy, and Spain), and the United Kingdom, and Japan from 2020 to 2034.

• According to secondary research, kyphoscoliosis affects approximately 2% of people in the US, mostly young children who are going through a growing spurt.
• Kyphoscoliosis affects approximately 1 in 1000 individuals, and about 1 in 10,000 affected individuals has a severe spinal deformity.
• Scheuermann disease, a frequent cause of kyphoscoliosis in adolescents, has a reported prevalence ranging from 0.4% to 8%, depending on diagnostic criteria and population sampled. It predominantly affects adolescents between the ages of 12 and 17 years, with a male predominance reported in several studies.
• The degree of thoracic kyphosis increases with age from 20 to 29 degrees in individuals younger than 40 years old, 53 degrees in those aged 60 to 74, and 66 degrees in patients older than 75 years.

Kyphoscoliosis Report Insights

• Patient Population
• Country-wise Epidemiology Distribution

Kyphoscoliosis Report Key Strengths

• Ten-Year Forecast
• 7MM Coverage
• Kyphoscoliosis Epidemiology Segmentation

Kyphoscoliosis Report Assessment

• Unmet Needs
• Current Diagnostic Practices

FAQs

• What are the disease risks, burdens, and unmet needs of kyphoscoliosis? What will be the growth opportunities across the 7MM concerning the patient population with kyphoscoliosis?
• What is the historical and forecasted kyphoscoliosis patient pool in the US, EU4 (Germany, France, Italy, and Spain), the UK, and Japan?

Reasons to buy

• Insights on patient burden/disease incidence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• To understand KOLs’ perspectives on the accessibility, acceptability, and compliance-related challenges of kyphoscoliosis to overcome barriers in the future.
• Detailed insights into various factors hampering disease diagnosis and other existing diagnostic challenges.