Lipoxygenase Inhibitor Lox Inhibitor Pipeline Insight

DelveInsight’s, “Lipoxygenase Inhibitor (LOX Inhibitor) - Pipeline Insight, 2022,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Lipoxygenase Inhibitor (LOX Inhibitor) pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. 

Geography Covered

  • Global coverage

Lipoxygenase Inhibitor (LOX Inhibitor) Understanding

Lipoxygenase Inhibitor (LOX Inhibitor): Overview

Lipoxygenase (LOX) is a kind of rate-limiting enzyme in the process of arachidonic acid metabolism into leukotriene (LT) which mediates the occurrence of inflammation. The inhibition of LOX can reduce LT, thereby producing an anti-inflammatory effect. Lipoxygenase (LOX) can catalyze fatty acid to produce a number of active metabolic products that are involved in a lot of vital diseases. For instance, type 1 and type 2 diabetes (or both), cardiovascular diseases, hypertension, renal diseases, and neurological conditions such as Alzheimer's disease and Parkinson's disease.


LOX inhibitors are developed more slowly than COX inhibitors due to a lack of specific structure of LOXs. Additionally, as a result of the coexistence of LOXs in the same organism, LOX inhibitors should be designed seriously so as to achieve the targeting effect. In particular, another regulatory domain that is different from the two known domains of the C-terminal catalytic domain and the N-terminal β-barrel domain has been found, which will provide new ideas for the design of new LOX inhibitors.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Lipoxygenase Inhibitor (LOX Inhibitor) R&D. The therapies under development are focused on novel approaches for Lipoxygenase Inhibitor (LOX Inhibitor).

Lipoxygenase Inhibitor (LOX Inhibitor) Emerging Drugs Chapters

This segment of the Lipoxygenase Inhibitor (LOX Inhibitor) report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.


Lipoxygenase Inhibitor (LOX Inhibitor) Emerging Drugs


Epeleuton: Afimmune

Epeleuton, previously named DS102, is 15-hydroxy eicosapentaenoic acid (15(S)-HEPE) ethyl ester, a second-generation synthetic n-3 fatty acid and derivative of an endogenous downstream metabolite of EPA. Epeleuton is a new chemical entity with additional therapeutic effects compared with other n-3 fatty acid. It acts as 5-Lipoxygenase Inhibitor (LOX Inhibitor) and is currently in Phase II of clinical trial for Alcoholic hepatitis, Chronic obstructive pulmonary disease, Diabetic neuropathies, Hypertriglyceridaemia, Idiopathic pulmonary fibrosis, Non-alcoholic fatty liver disease, Non-alcoholic steatohepatitis, Type 2 diabetes mellitus.


Tipelukast: MediciNova

Tipelukast is being developed by MediciNova and is in Phase II forIdiopathic pulmonary fibrosis, Non-alcoholic steatohepatitis. It acts as 5-Lipoxygenase Inhibitor (LOX Inhibitor).

Further product details are provided in the report……..

Lipoxygenase Inhibitor (LOX Inhibitor): Therapeutic Assessment

This segment of the report provides insights about the different Lipoxygenase Inhibitor (LOX Inhibitor) drugs segregated based on following parameters that define the scope of the report, such as:

  • Major Players working on Lipoxygenase Inhibitor (LOX Inhibitor)

There are approx. 10+ key companies which are developing the Lipoxygenase Inhibitor (LOX Inhibitor). The companies which have their Lipoxygenase Inhibitor (LOX Inhibitor) drug candidates in the most advanced stage, i.e. phase II include, Afimmune.

Phases

DelveInsight’s report covers around 10+ products under different phases of clinical development like

  • Late-stage products (Phase III and
  • Mid-stage products (Phase II and
  • Early-stage products (Phase I/II and Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration


Lipoxygenase Inhibitor (LOX Inhibitor) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Infusion
  • Intradermal
  • Intramuscular
  • Intranasal
  • Intravaginal
  • Oral
  • Parenteral
  • Subcutaneous
  • Topical
  • Molecule Type


Products have been categorized under various Molecule types such as

  • Vaccines
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Lipoxygenase Inhibitor (LOX Inhibitor): Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Lipoxygenase Inhibitor (LOX Inhibitor) therapeutic drugs key players involved in developing key drugs.


Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Lipoxygenase Inhibitor (LOX Inhibitor) drugs.

Lipoxygenase Inhibitor (LOX Inhibitor) Report Insights

  • Lipoxygenase Inhibitor (LOX Inhibitor) Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Lipoxygenase Inhibitor (LOX Inhibitor) Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Scenario and Emerging Therapies:

  • How many companies are developing Lipoxygenase Inhibitor (LOX Inhibitor) drugs?
  • How many Lipoxygenase Inhibitor (LOX Inhibitor) drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for Lipoxygenase Inhibitor (LOX Inhibitor)?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Lipoxygenase Inhibitor (LOX Inhibitor) therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Lipoxygenase Inhibitor (LOX Inhibitor) and their status?
  • What are the key designations that have been granted to the emerging drugs?

Introduction

Executive Summary

Lipoxygenase Inhibitor (LOX Inhibitor): Overview

  • Structure
  • Mechanism of Action

Pipeline Therapeutics

  • Comparative Analysis

Therapeutic Assessment

  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type

Lipoxygenase Inhibitor (LOX Inhibitor) - DelveInsight’s Analytical Perspective

In-depth Commercial Assessment

  • Lipoxygenase Inhibitor (LOX Inhibitor) companies’ collaborations, Licensing, Acquisition -Deal Value Trends

Lipoxygenase Inhibitor (LOX Inhibitor) Collaboration Deals

  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis

Mid Stage Products (Phase II)

  • Comparative Analysis

Epeleuton: Afimmune

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Early Stage Products (Phase I)

  • Comparative Analysis

PTC 857: BioElectron Technology

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Pre-clinical and Discovery Stage Products

  • Comparative Analysis

VLX 1005: Veralox Therapeutics

  • Product Description
  • Research and Development
  • Product Development Activities

Drug profiles in the detailed report…..

Inactive Products

  • Comparative Analysis

Lipoxygenase Inhibitor (LOX Inhibitor) Key Companies

Lipoxygenase Inhibitor (LOX Inhibitor) Key Products

Lipoxygenase Inhibitor (LOX Inhibitor)- Unmet Needs

Lipoxygenase Inhibitor (LOX Inhibitor)- Market Drivers and Barriers

Lipoxygenase Inhibitor (LOX Inhibitor)- Future Perspectives and Conclusion

Lipoxygenase Inhibitor (LOX Inhibitor) Analyst Views

Lipoxygenase Inhibitor (LOX Inhibitor) Key Companies

Appendix

List of Table

Table 1: Total Products for Lipoxygenase Inhibitor (LOX Inhibitor)

Table 2: Late Stage Products

Table 3: Mid Stage Products

Table 4: Early Stage Products

Table 5: Pre-clinical & Discovery Stage Products

Table 6: Assessment by Product Type

Table 7: Assessment by Stage and Product Type

Table 8: Assessment by Route of Administration

Table 9: Assessment by Stage and Route of Administration

Table 10: Assessment by Molecule Type

Table 11: Assessment by Stage and Molecule Type

Table 12: Inactive Products

List of Figures

Figure 1: Total Products for Lipoxygenase Inhibitor (LOX Inhibitor)

Figure 2: Late Stage Products

Figure 3: Mid Stage Products

Figure 4: Early Stage Products

Figure 5: Preclinical and Discovery Stage Products

Figure 6: Assessment by Product Type

Figure 7: Assessment by Stage and Product Type

Figure 8: Assessment by Route of Administration

Figure 9: Assessment by Stage and Route of Administration

Figure 10: Assessment by Molecule Type

Figure 11: Assessment by Stage and Molecule Type

Figure 12: Inactive Products      

• Afimmune

• MediciNova

• Mariposa Health Limited

• MedWell Laboratories

• BioElectron Technology

• CSPC Ouyi Pharmaceutical

• Veralox Therapeutics

• Qurient Therapeutics

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