DelveInsight’s, “MALT1 Protein Inhibitors – Pipeline Insight, 2022,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in MALT1 Protein Inhibitors pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
MALT1 Protein Inhibitors: Overview
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 is a protein that in humans is encoded by the MALT1 gene. MALT1 is a paracaspase, which is related to the caspase (cysteine-aspartic proteases) family of proteases but cleaves after Arg residues instead of Asp. MALT1 cleavage activity is linked to the pathogenesis of activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL), a chemoresistant form of DLBCL. MALT1 is a unique paracaspase protein that transduces aberrant oncogenic signaling in ABC-DLBCL. MALT1 represents a potentially important therapeutic target for ABC-DLBCL and MALT lymphoma. MALT1 small molecule inhibitors might be useful chemical tools for studying MALT1 biology and treating MALT1-addicted tumors.
"MALT1 Protein Inhibitors - Pipeline Insight, 2022" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the MALT1 Protein Inhibitors pipeline landscape is provided which includes the disease overview and MALT1 Protein Inhibitors treatment guidelines. The assessment part of the report embraces, in depth MALT1 Protein Inhibitors commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, MALT1 Protein Inhibitors collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
The companies and academics are working to assess challenges and seek opportunities that could influence MALT1 Protein Inhibitors R&D. The therapies under development are focused on novel approaches to treat/improve MALT1 Protein Inhibitors.
This segment of the MALT1 Protein Inhibitors report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
MALT1 Protein Inhibitors Emerging Drugs
MPT-0118: Monopteros Therapeutics
MPT-0118, a first-in-class MALT1 inhibitor for the treatment of solid tumors, has dosed the first patient in its Phase 1/1b dose escalation and cohort expansion clinical trial. Inhibition of MALT1 results in the selective reprogramming of the tumor-associated Tregs, characterized by the loss of their immunosuppressive function and pro-inflammatory interferon-gamma production. Treg reprogramming through MPT-0118 therefore has the potential to enable a powerful anti-tumor immune attack in cancer patients that are otherwise not responsive to checkpoint inhibitor therapy.
Further product details are provided in the report……..
This segment of the report provides insights about the different MALT1 Protein Inhibitors drugs segregated based on following parameters that define the scope of the report, such as:
There are approx. 5+ key companies which are developing the therapies for MALT1 Protein Inhibitors. The companies which have their MALT1 Protein Inhibitors drug candidates in the most advanced stage, i.e. phase I include Monopteros Therapeutics.
DelveInsight’s report covers around 5+ products under different phases of clinical development like
MALT1 Protein Inhibitors pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Products have been categorized under various Molecule types such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses MALT1 Protein Inhibitors therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging MALT1 Protein Inhibitors drugs.
Current Treatment Scenario and Emerging Therapies:
Introduction
Executive Summary
MALT1 Protein Inhibitors: Overview
Pipeline Therapeutics
Therapeutic Assessment
Early Stage Products (Phase I)
MPT-0118: Monopteros Therapeutics
Drug profiles in the detailed report…..
Preclinical Stage Products
Research programme: MALT-1 inhibitors - C4X Discovery
Drug profiles in the detailed report…..
Inactive Products
MALT1 Protein Inhibitors Key Companies
MALT1 Protein Inhibitors Key Products
MALT1 Protein Inhibitors- Unmet Needs
MALT1 Protein Inhibitors- Market Drivers and Barriers
MALT1 Protein Inhibitors- Future Perspectives and Conclusion
MALT1 Protein Inhibitors Analyst Views
MALT1 Protein Inhibitors Key Companies
Appendix
List of Table
Table 1: Total Products for MALT1 Protein Inhibitors
Table 2: Late Stage Products
Table 3: Mid Stage Products
Table 4: Early Stage Products
Table 5: Pre-clinical & Discovery Stage Products
Table 6: Assessment by Product Type
Table 7: Assessment by Stage and Product Type
Table 8: Assessment by Route of Administration
Table 9: Assessment by Stage and Route of Administration
Table 10: Assessment by Molecule Type
Table 11: Assessment by Stage and Molecule Type
Table 12: Inactive Products
List of Figures
Figure 1: Total Products for MALT1 Protein Inhibitors
Figure 2: Late Stage Products
Figure 3: Mid Stage Products
Figure 4: Early Stage Products
Figure 5: Preclinical and Discovery Stage Products
Figure 6: Assessment by Product Type
Figure 7: Assessment by Stage and Product Type
Figure 8: Assessment by Route of Administration
Figure 9: Assessment by Stage and Route of Administration
Figure 10: Assessment by Molecule Type
Figure 11: Assessment by Stage and Molecule Type
Figure 12: Inactive Products
• Rheos Medicines
• Monopteros Therapeutics
• Janssen Research & Development
• Aurigene Discovery Technologies
• C4X Discovery
• AbbVie
