Post-Surgical Pain Market

• The Post-Surgical Pain Market Size is anticipated to increase with a notable CAGR during the forecast period (2023-2032).
• The leading Post-Surgical Pain Companies such as AbbVie (Allergan), Heron Therapeutics, Cali Biosciences, Acadia Pharmaceuticals, Virpax Pharmaceuticals, GlaxoSmithKline Plc, Pacira Pharmaceuticals Inc., Johnson & Johnson (Janssen Pharmaceuticals), AFT Pharmaceuticals, Alembic Pharmaceuticals, InvaGen Pharmaceuticals Inc., SiteOne Therapeutics, Pfizer Inc., and others are debveloping therapies for Post-Surgical Pain Treatment.
• Up to 88% of patients may suffer post-operative pain, and of those, 34-62% will likely describe it as moderate to severe. 

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DelveInsight’s “Post-Surgical Pain Market Insights, Epidemiology, and Market Forecast – 2032” report delivers an in-depth understanding of the Post-Surgical Pain, historical and forecasted epidemiology as well as the Post-Surgical Pain market trends in the United States, EU4 (Germany, France, Italy, Spain), and  the United Kingdom, and Japan.

The Post-Surgical Pain market report provides current treatment practices, emerging drugs, Post-Surgical Pain market share of the individual therapies, and current and forecasted Post-Surgical Pain market size from 2019 to 2032, segmented by seven major markets. The report also covers current Post-Surgical Pain treatment practices/algorithms and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.

Geography Covered

• The United States
• EU4 (Germany, France, Italy, Spain), and the United Kingdom
• Japan

Study period: 2019–2032

Post-Surgical Pain Understanding and Treatment Algorithm

The DelveInsight’s Post-Surgical Pain market report gives a thorough understanding of Post-Surgical Pain by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis, and treatment.

Post-Surgical Pain Overview

Postoperative pain is an anticipated and temporary increase in background pain that occurs following surgical procedures. It is a type of pain that typically lasts less than a few days to months or pain directly related to soft tissue damage such as a sprained ankle or a paper cut. The pain is of short duration, but it gradually resolves as the injured tissues heal. It is further classified as acute and chronic pain based on the duration.

Post-Surgical Pain Diagnosis

Proper diagnosis of the type and intensity of pain is crucial for an adequate and targeted treatment of acute pain. It requires a highly professional approach in terms of expertise, psychology, and ethics. The examination of acute postoperative pain involved medical history, physical examination, and specific evaluation of pain; measuring pain; rating scales provide a simple means for patients to rate pain intensity; verbal expression to assess the intensity of pain and other assessments.

Post-Surgical Pain Treatment

Postoperative pain management aims not only to decline pain intensity but also to increase patient comfort and to improve postoperative outcomes. Pharmacologic therapies for pain include drugs from several drug classes. Pain-relieving analgesics include opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen. Providers also elect to manage acute pain with benzodiazepines, muscle relaxants, antidepressants, alpha-2 agonists, gamma-aminobutyric agonists, and cannabinoids. Topical agents, such as capsaicin and lidocaine, are also used.

Post-Surgical Pain Epidemiology

The Post-Surgical Pain epidemiology section provides insights into historical and current Post-Surgical Pain patient pool and forecasted trends for seven individual major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Post-Surgical Pain report also provides the diagnosed patient pool, their trends and assumptions undertaken.

Key findings

The Post-Surgical Pain epidemiology covered in the report provides historical as well as forecasted Post-Surgical Pain epidemiology [segmented as Total number of surgical procedures, Total incident cases of Post-surgical pain, and Severity-specific incident cases of Post-surgical pain] in the 7MM covering the United States, EU4 (Germany, France, Italy, Spain), and the United Kingdom, and Japan from 2019 to 2032.

Country-wise Post-Surgical Pain Epidemiology

The epidemiology segment also provides the Post-Surgical Pain epidemiology data and findings across the United States, EU4 (Germany, France, Italy, Spain), and the United Kingdom, and Japan.

Post-Surgical Pain Drug Chapters

The drug chapter segment of the Post-Surgical Pain report encloses the detailed analysis of Post-Surgical Pain marketed drugs and late-stage (Phase III and Phase II) Post-Surgical Pain pipeline drugs. It also helps understand the Post-Surgical Pain clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

Post-Surgical Pain Marketed Drugs

Zalviso: AcelRx Pharmaceuticals

Zalviso is a drug/device combination product designed to deliver 15 mcg sufentanil, a high therapeutic index opioid, formulated in a proprietary noninvasive sublingual dosage form via a novel hand-held, pre-programmed, patient-controlled analgesia system. Zalviso is approved in the European Union, it remains an investigational product in the United States.

Olinvyk (Olinvo) (oliceridine): Trevena, Inc.

OLINVYK is an opioid agonist indicated in adults for the management of acute pain severe enough to require an intravenous opioid analgesic and for whom alternative treatments are inadequate.

Note: Detailed Current therapies assessment will be provided in the full report...

Emerging Post-Surgical Pain Drugs

PRF-110: PainReform LTD

PainReform LTD is developing PRF-110, a viscous clear oil-based solution instilled (deposited) directly into the surgical wound and spreadable over the complete wound surface to provide localized and extended postoperative analgesia. Also, Phase III study design has been IND approved; FDA confirmed 505(b)(2) designation. The company is anticipating study readouts ~9 months after dosing the first patient and NDA submission ~22 months following Phase III trial initiation.

OCS-01: Oculis

Oculis is developing OCS-01 (dexamethasone cyclodextrin nanoparticle ophthalmic suspension 1.5% mg/mL), a novel formulation of dexamethasone using Oculis proprietary Solubilizing Nanoparticle (SNP) technology. OCS-01 has successfully completed a Phase II trial in inflammation and pain following cataract surgery (SKYGGN trial), with 153 patients providing the first POC of a once-daily topical steroid.

Note: Detailed emerging therapies assessment will be provided in the full report...

Post-Surgical Pain Market Outlook

Postoperative pain management aims not only to decline pain intensity but also to increase patient comfort and to improve postoperative outcomes. Pharmacologic therapies for pain include drugs from several drug classes. Pain-relieving analgesics include opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen. Providers also elect to manage acute pain with benzodiazepines, muscle relaxants, antidepressants, alpha-2 agonists, gamma-aminobutyric agonists, and cannabinoids. Topical agents, such as capsaicin and lidocaine, are also used.

NSAIDs are a sensible choice because of their effectiveness after surgical procedures. However, before surgeons start prescribing NSAIDs in place of opioids, it is crucial first to understand their potential postoperative complications. NSAIDs provide anti-inflammatory, antipyretic, analgesic, and thrombotic effects through the inhibition of the enzymes cyclooxygenases 1 and 2 (COX-1 and COX-2).

According to DelveInsight, the Post-Surgical Pain market in 7MM is expected to witness a major change in the study period 2019–2032.

Key findings

This section includes a glimpse of the Post-Surgical Pain market in 7MM.

The United States: Post-Surgical Pain Market Outlook

This section provides the total Post-Surgical Pain market size and market size by therapies in the United States.

EU4 and the UK Countries: Post-Surgical Pain Market Outlook

The total Post-Surgical Pain market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.

Japan: Post-Surgical Pain Market Outlook

The total Post-Surgical Pain market size and market size by therapies in Japan are also mentioned.

Post-Surgical Pain Drug Uptake

This section focuses on the rate of uptake of the potential drugs recently launched in the Post-Surgical Pain market or expected to get launched in the market during the study period 2019–2032. The analysis covers Post-Surgical Pain market uptake by drugs, patient uptake by therapies, and sales of each drug. 

This will help in understanding the Post-Surgical Pain drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on market share and size, which again will be useful in investigating factors important in the market uptake and in making financial and regulatory decisions.

Post-Surgical Pain Pipeline Development Activities

The Post-Surgical Pain report provides insights into Post-Surgical Pain Clinical Trials within Phase II, and Phase III stages. It also analyses Post-Surgical Pain’s key players involved in developing targeted therapeutics.

Post-Surgical Pain market clinical trial development activities

The report covers detailed information on collaborations, acquisitions, and mergers, licensing patent details, and other information for Post-Surgical Pain emerging therapies.

Post-Surgical Pain Reimbursement Scenario

Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

KOL Views

To keep up with current epidemiology and market trends, we take KOLs and SMEs' opinions working in the Post-Surgical Pain domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies and treatment patterns along with Post-Surgical Pain market trends. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the market and the unmet needs.

Competitive Intelligence Analysis

We perform competitive and market intelligence analysis of the Post-Surgical Pain market by using various competitive intelligence tools that include – SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.

Scope of the Post-Surgical Pain Market Report

• Descriptive overview of Post-Surgical Pain, disease overview, patient journeys, treatment algorithms, diagnosis, and currently available therapies
• Comprehensive insight into the Post-Surgical Pain epidemiology and forecasts in the 7MM
• An all-inclusive account of both the current and emerging therapies for Post-Surgical Pain, along with the assessment of new therapies, expected to have an impact on the current treatment landscape
• Exhaustive analysis of the Post-Surgical Pain market; historical and forecasted covering drug outreach in the 7MM
• Detailed patient-based market forecasting determines the trends shaping and driving the global Post-Surgical Pain market

Post-Surgical Pain Market Report Highlights

• In the coming years, the Post-Surgical Pain market is set to change due to the rising awareness of the disease and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
• The companies and academics are working to assess challenges and seek opportunities that could influence Post-Surgical Pain R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition  
• Major players are involved in developing Post-Surgical Pain therapies. The launch of emerging therapies will significantly impact the Post-Surgical Pain market
• A better understanding of Post-Surgical Pain pathogenesis will also contribute to the development of novel therapeutics for Post-Surgical Pain.
• Our in-depth analysis of the Post-Surgical Pain pipeline assets across different stages of development (Phase III and Phase II), emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

Post-Surgical Pain Report Insights

• Patient-Based Market Forecasting
• Post-Surgical Pain Therapeutic approaches
• Post-Surgical Pain pipeline analysis
• Post-Surgical Pain market size and trends
• Post-Surgical Pain market opportunities
• Impact of Upcoming Post-Surgical Pain Therapies

Post-Surgical Pain Report Key Strengths

• 10 year forecast
• 7MM Coverage
• Post-Surgical Pain epidemiology segmentation
• Key cross competition
• KOL views
• Post-Surgical Pain drugs uptake

Post-Surgical Pain Report Assessment

• Current Post-Surgical Pain treatment practices
• Post-Surgical Pain Unmet needs
• Post-Surgical Pain pipeline product profiles
• Post-Surgical Pain market attractiveness
• Post-Surgical Pain Market Drivers
• Post-Surgical Pain Market Barreirs

Key Questions Answered In The Post-Surgical Pain Market Report

Post-Surgical Pain market insights:

• What would be the Post-Surgical Pain market growth till 2032, and what will be the resultant market size in 2032?
•  What was the Post-Surgical Pain drug class share (in percentage) distribution in 2019, and how would it look in 2032?
• What would be the Post-Surgical Pain total market size and market size by therapies across the 7MM during the forecast period (2023–2032)?
• What are the key findings of the market across 7MM, and which country will have the largest Post-Surgical Pain market size during the forecast period (2023–2032)?
• How would the unmet needs affect the Post-Surgical Pain market dynamics and subsequent analysis of the associated trends?

Surgical Pain Epidemiology Insights:

• What are the disease risk, burden, and regional/ethnic differences of Post-Surgical Pain?
• What is the historical and forecasted Post-Surgical Pain patient pool in 7MM, and where can one observe the highest patient population and growth opportunities?
• What are the key factors driving the epidemiology trends for seven major markets covering the United States, EU4 (Germany, France, Italy, Spain), and the UK, and Japan?

Current Treatment Scenario, Marketed Drugs, and Emerging Therapies

• What are the current treatment guidelines and treatment options, in addition to approved therapies for Post-Surgical Pain in the US, Europe, and Japan?
• What are the key collaborations (Industry–Industry, Industry-Academia), mergers and acquisitions, and licensing activities related to Post-Surgical Pain therapies?
• What are the recent novel therapies, targets, mechanisms of action, and technologies being developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for Post-Surgical Pain and its status, along with the challenges faced?

Reasons to Buy Post-Surgical Pain Market Report

• The patient-based market forecast analysis will help in developing business strategies by understanding trends shaping and driving the Post-Surgical Pain market
• Organize sales and marketing efforts by identifying the best opportunities for Post-Surgical Pain in the US, EU4 (Germany, France, Italy, Spain), and the United Kingdom, and Japan
• Identification of strong upcoming players in the market that will help devise strategies that will help in getting ahead of competitors