Rotator Cuff Injuries Market

 

Key Highlights

 

• According to a study by Varacallo et al.(2022) , on a global basis, millions of individuals are affected with rotator cuff syndrome (RCS) and its related diseases. RCS affects patients at varying levels of intensity depending on their age, ranging from 5% to 10% of patients under the age of 20 to over 60% of individuals over the age of 80. Age-related RC changes include collagen fiber disorientation and myxoid degeneration. Also there is a correlation between smoking and RC degeneration, symptomatic cuff tears, and even the increase in the size of the cuff tear when present.

 

• The disease epidemiology covered in the report provides historical as well as forecasted Rotator Cuff Injuries epidemiology [segmented as Total Prevalent cases of Rotator Cuff Injury, Age-specific Prevalence of Rotator Cuff Injury, Etiology-specific Prevalence of Rotator Cuff Injury, and Diagnosed and Treatable cases of Rotator Cuff Injury] in the 7MM covering the United States, EU4 countries (Germany, France, Italy, Spain) the United Kingdom, and Japan from 2019 to 2032.

 

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DelveInsight's "Rotator Cuff Injuries Market Insights, Epidemiology, and Market Forecast — 2032" report delivers an in-depth understanding of the Rotator Cuff Injuries, historical and forecasted epidemiology as well as the Rotator Cuff Injuries market trends in the United States, EU4 (Germany, Spain, Italy, France) and the United Kingdom, and Japan.

 

The Rotator Cuff Injuries market report provides current treatment practices, emerging drugs, Rotator Cuff Injuries market share of the individual therapies, current and forecasted Rotator Cuff Injuries market size from 2019 to 2032 segmented by seven major markets. The Report also covers current Rotator Cuff Injuries treatment practice/algorithm, and unmet medical needs to curate best of the opportunities and assess the underlying potential of the market.

 

Geography Covered

• The United States
• EU4 (Germany, France, Italy, Spain), and the United Kingdom
• Japan

 

Study Period: 2019–2032

 

Rotator Cuff Injuries Market Disease Understanding and Treatment Algorithm

The rotator cuff is a set of muscles and tendons that surrounds the shoulder joint and retains the upper arm bone's head securely within the shoulder's shallow socket. A rotator cuff injury can result in a dull aching in the shoulder that typically gets worse when the arm is used away from the body. The rotator cuff is a commonly injured area. The most common injuries are strains, tears, and tendinitis.

 

The etiology of rotator cuff disease is complex and multifactorial, including age-related degeneration, micro trauma, and macro trauma. Smoking, hypercholesterolemia, and genetics have all been shown to influence the development of rotator cuff tearing. Age is the most common factor of them all for rotator cuff disease due to progressive degeneration or wear and tear of the tendon tissue. Repetitive overhead activity or heavy lifting over a prolonged period of time may irritate or damage the tendon.

 

The symptoms associated with a rotator cuff injury include, a dull ache deep in the shoulder, disturbed sleep, difficulty to reach the back and arm weakness. Pain with overhead activity, localizing to the deltoid region, and loss of active range of motion of the shoulder are among the most common presenting symptoms.

 

Rotator Cuff Injuries Diagnosis

During physical examination, doctor presses on different parts of the shoulder and move the arm into different positions. X-rays, Ultrasound and Magnetic resonance imaging (MRI) are various imaging tests recommended to confirm diagnosis.

 

Rotator Cuff Injuries Treatment

Physical therapy to surgical repair employing a variety of procedures are among the treatment options available, depending on the severity of the condition and the patient's symptoms. To heal from a rotator cuff injury, conservative therapies such as rest, ice, and physical therapy are required. If conservative therapy fail, the doctor may provide a steroid injection. Physical therapy is usually one of the first treatments suggested and is also an important part of the recovery process after rotator cuff surgery. Surgeries for rotator cuff injuries if the injury is severe include Arthroscopic tendon repair, Open tendon repair, Tendon transfer and Shoulder replacement.

 

Rotator Cuff Injuries Epidemiology 

The Rotator Cuff Injuries epidemiology section provides insights about historical and current Rotator Cuff Injuries patient pool and forecasted trends for individual seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

 

Key Findings

 

• According to a study by Varacallo et al.(2022) , on a global basis, millions of individuals are affected with rotator cuff syndrome (RCS) and its related diseases. RCS affects patients at varying levels of intensity depending on their age, ranging from 5% to 10% of patients under the age of 20 to over 60% of individuals over the age of 80. Age-related RC changes include collagen fiber disorientation and myxoid degeneration. Also there is a correlation between smoking and RC degeneration, symptomatic cuff tears, and even the increase in the size of the cuff tear when present.

 

• In a prospective German population study by Tempelhof et al., (1999) on 411 volunteers, there was 23% overall prevalence of RC tears with 31% in those of age 70 and 51% in those aged 80. Therefore a high rate of rotator cuff tears in patients with asymptomatic shoulders was thus observed with increasing patient age. 

 

• A study by Yamaguchi et al., (2006) showed that the prevalence of rotator cuff tear increases with age. According to the study the group of patients without rupture had a mean age of 48 years, those with unilateral lesions had 58 years and the ones with bilateral tears had a mean of 67 years. 

 

• The disease epidemiology covered in the report provides historical as well as forecasted Rotator Cuff Injuries epidemiology [segmented as Total Prevalent cases of Rotator Cuff Injury, Age-specific Prevalence of Rotator Cuff Injury, Etiology-specific Prevalence of Rotator Cuff Injury, and Diagnosed and Treatable cases of Rotator Cuff Injury] in the 7MM covering the United States, EU4 countries (Germany, France, Italy, Spain) the United Kingdom, and Japan from 2019 to 2032.

 

Country Wise- Rotator Cuff Injuries Epidemiology

This section provides a glimpse of the Rotator Cuff Injuries epidemiology in the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

Rotator Cuff Injuries Recent Developments

• In February 2025, Atreon Orthopedics, LLC, a Columbus-based innovator in tissue healing, announced FDA 510(k) clearance and the full market launch of BioCharge® Autobiologic Matrix. This bioresorbable synthetic implant is designed to improve rotator cuff repair integrity and long-term patient outcomes.

Rotator Cuff Injuries Drug Chapters

The drug chapter segment of the Rotator Cuff Injuries report encloses the detailed analysis of Rotator Cuff Injuries marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the Rotator Cuff Injuries clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

 

Rotator Cuff Injuries Marketed Drugs

Note: Detailed Current therapies assessment will be provided in the full report of Rotator Cuff Injuries

 

Rotator Cuff Injuries Emerging Drugs

Ortho-R/PRP, being developed by Ortho Regenerative Technologies, is a freeze-dried chitosan-platelet-rich plasma (PRP) hybrid. It is a drug/biologic combination product containing a chitosan component and trehalose. It is also a disaccharide that acts as a lyoprotectant during the lyophilization process and calcium chloride, which acts as a PRP coagulation agent. This formulation augments the healing rate of occupational and sports related injuries. The physicochemical configuration of this proprietary biopolymer matrix acts as a biodegradable mucoadhesive scaffold that chemically interacts with the PRP biologic components thereby increasing the residency time of the PRP bioactive material delivered at the surgically repaired site, leading to prolonged release of growth factors from PRP, enhancing the therapeutic effect. The drug is currently being evaluated for its safety in Phase I/II trials.

 

Angiocrine Bioscience is developing E-CEL UVEC (AB-207), an investigational product consists of endothelial cells derived from the walls of the blood vessels of human umbilical cords that have been genetically modified to maintain their stability and their regenerative properties. In its preclinical studies the cell therapy showed accelerated healing and an increase in the strength of the tendon attachment at the repair site. The US FDA has granted Investigational New Drug (IND) status to the cell therapy which is currently being evaluated in Phase Ib/II. 

 

REGENETEN Bioinductive Implant (Smith & Nephew): The REGENETEN Bioinductive Implant, comprises of type 1 collagen, is an advanced healing solution for biological enhancement and tendon regeneration across all rotator cuff tear types. It stimulates a natural healing response to induce new tendon-like tissue growth and disrupt rotator cuff disease progression across the tear spectrum. 

 

Note: Detailed emerging therapies assessment will be provided in the full report of Rotator Cuff Injuries

 

Rotator Cuff Injuries Market Outlook

The treatment depends on the age of the patient, their functional demands, and the acuteness or chronicity of the tear. For complete tears in patients under 40, surgical treatment is the generally recommended treatment followed by appropriate rehabilitation. These are usually traumatic injuries and respond well to surgery. 

 

The American Academy of Orthopedic Surgeons developed recommendations determining high-level evidence of surgical treatment for full-thickness tears was weak. 

 

First, non-surgical management is always appropriate, providing they are responding with improved function and decreased pain. Second, repairs can be appropriate even if the patient responds to non-surgical care. Third, for those healthy patients who remain symptomatic, then repair is the appropriate treatment. Fourth, for cases of chronic, massive tears, debridement/partial repair and/or reconstruction may be indicated. Finally, for those with painful pseudo paralysis with an irreparable tear, arthroplasty may be appropriate.

 

Pain control and inflammation reduction are initially required to allow progression of healing and initiation of an active rehabilitation program in patients with a rotator cuff injury. Conservative treatments such as rest, ice, acetaminophen and physical therapy are needed to recover from a rotator cuff injury. If injury is severe, surgery becomes needful. If conservative treatments fail to reduce pain, steroid based injection into shoulder joint is recommended. While such shots are often temporarily helpful, they should be used judiciously, as they can contribute to weakening of the tendon and may lower the success of surgery if this is eventually needed.

 

Therapy: Physical therapy is usually one of the first treatments that doctors suggest. Exercises tailored to the specific location of rotator cuff injury helps to restore flexibility and give strength to the shoulder. Physical therapy is also an important part of the recovery process after rotator cuff surgery.

 

Arthroscopic tendon repair: In this procedure, surgeons insert a tiny camera (arthroscope) and tools through small incisions to reattach the torn tendon to the bone.

 

Open tendon repair: In some situations, an open tendon repair may be a better option. In these types of surgeries, surgeon works through a larger incision to reattach the damaged tendon to the bone.

 

Tendon transfer: If the torn tendon is too damaged to be reattached to the arm bone, surgeons may decide to use a nearby tendon as a replacement.

 

Shoulder replacement: Massive rotator cuff injuries may require shoulder replacement surgery. To improve the artificial joint's stability, an innovative procedure (reverse shoulder arthroplasty) installs the ball part of the artificial joint onto the shoulder blade and the socket part onto the arm bone.

 

Over-the-counter pain relievers: The pain from a minor rotator cuff injury often diminishes on its own, with proper care. Over-the-counter pain relievers such as ibuprofen (Advil, Motrin IB) or acetaminophen (Tylenol, others) also may be helpful.

According to DelveInsight, the Rotator Cuff Injuries market in 7MM is expected to witness a major change in the study period 2019-2032.

 

Rotator Cuff Injuries Drugs Uptake

This section focuses on the rate of uptake of the potential drugs recently launched in the Rotator Cuff Injuries market or expected to get launched in the market during the study period 2019-2032. The analysis covers Rotator Cuff Injuries market uptake by drugs; patient uptake by therapies; and sales of each drug.

 

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs, and allows the comparison of the drugs based on market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions. 

 

Note: Detailed emerging therapies assessment will be provided in the full report of Rotator Cuff Injuries.

 

Rotator Cuff Injuries Pipeline Development Activities

The report provides insights into different therapeutic candidates in Phase II and Phase III stage. It also analyzes Rotator Cuff Injuries key players involved in developing targeted therapeutics.

 

Rotator Cuff Injuries Clinical Trials Development Activities

The Rotator Cuff Injuries clinical trials report covers the detailed information of collaborations, acquisition and merger, licensing, patent details and other information for Rotator Cuff Injuries emerging therapies.

 

Reimbursement Scenario in Rotator Cuff Injuries

Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

 

KOL- Views

To keep up with current market trends, we take KOLs and SMEs ' opinions working in the Rotator Cuff Injuries domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies treatment patterns or Rotator Cuff Injuries market trends. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the market and the Rotator Cuff Injuries unmet needs.

 

Competitive Intelligence Analysis

We perform Competitive and Market Intelligence analysis of the Rotator Cuff Injuries Market by using various Competitive Intelligence tools that include - SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies etc. The inclusion of the analysis entirely depends upon the data availability.

 

Scope of the Rotator Cuff Injuries Market Report

• The report covers the descriptive overview of Rotator Cuff Injuries, explaining its causes, signs and symptoms, pathophysiology, diagnosis, and currently available therapies
• Comprehensive insight has been provided into the Rotator Cuff Injuries epidemiology and treatment in the 7MM
• Additionally, an all-inclusive account of both the current and emerging therapies for Rotator Cuff Injuries are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
• A detailed review of the Rotator Cuff Injuries market; historical and forecasted is included in the report, covering drug outreach in the 7MM
• Detailed Patient Based Rotator Cuff Injuries Market Forecasting determines the trends shaping and driving the global Rotator Cuff Injuries market

 

Rotator Cuff Injuries Market Report Highlights

• In the coming years, the Rotator Cuff Injuries market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
• The companies and academics are working to assess challenges and seek opportunities that could influence Rotator Cuff Injuries R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition      
• Major players are involved in developing therapies for Rotator Cuff Injuries. The launch of emerging therapies will significantly impact the Rotator Cuff Injuries market
• A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Rotator Cuff Injuries
• Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

 

Rotator Cuff Injuries Report Insights

• Patient Based Rotator Cuff Injuries Market Forecasting
• Rotator Cuff Injuries Therapeutic Approaches
• Rotator Cuff Injuries Pipeline Analysis
• Rotator Cuff Injuries Market Size and Trends
• Rotator Cuff Injuries Market Opportunities
• Impact of upcoming Therapies

 

Rotator Cuff Injuries Report Key Strengths

• 11 Years Forecast
• 7MM Coverage
• Rotator Cuff Injuries Epidemiology Segmentation
• Key Cross Competition
• Highly Analyzed Market
• Drugs Uptake

 

Rotator Cuff Injuries Report Assessment

• Current Treatment Practices
• Unmet Needs
• Pipeline Product Profiles
• Market Attractiveness

 

Key Questions

 

Rotator Cuff Injuries Market Insights:

• What was the Rotator Cuff Injuries drug class share (%) distribution in 2019 and how it would look like in 2032?
• What would be the Rotator Cuff Injuries total market size as well as market size by therapies across the 7MM during the forecast period (2019-2032)?
• What are the key findings of the market across 7MM and which country will have the largest Rotator Cuff Injuries market size during the forecast period (2019-2032)?
• At what CAGR, the Rotator Cuff Injuries market is expected to grow by 7MM during the forecast period (2019-2032)?
• What would be the Rotator Cuff Injuries market outlook across the 7MM during the forecast period (2019-2032)?
• What would be the Rotator Cuff Injuries market growth till 2032, and what will be the resultant market Size in the year 2032?
• How would the Rotator Cuff Injuries unmet needs affect the market dynamics and subsequent analysis of the associated trends?

 

Rotator Cuff Injuries Epidemiology Insights:

• What are the disease risk, burden, and regional/ethnic differences of Rotator Cuff Injuries?
• What are the key factors driving the epidemiology trend for seven major markets covering the United States, EU4 (Germany, Spain, France, Italy) and the UK, and Japan?
• What is the historical Rotator Cuff Injuries patient pool in seven major markets covering the United States, EU4 (Germany, Spain, France, Italy) and  the UK, and Japan?
• What would be the forecasted patient pool of Rotator Cuff Injuries in seven major markets covering the United States, EU4 (Germany, Spain, France, Italy) and  the UK, and Japan?
• Where will be the growth opportunities in the 7MM concerning the patient population about Rotator Cuff Injuries?
• Out of all 7MM countries, which country would have the highest incident population of Rotator Cuff Injuries during the forecast period (2019-2032)?
• At what CAGR the patient population is expected to grow by 7MM during the forecast period (2019-2032)?

 

Current Treatment Scenario, Rotator Cuff Injuries Marketed Drugs, and Rotator Cuff Injuries Emerging Therapies:

• What are the current options for the Rotator Cuff Injuries treatment in addition to the approved therapies?
• What are the current treatment guidelines for the treatment of Rotator Cuff Injuries in the US, Europe, and Japan?
• What are the Rotator Cuff Injuries marketed drugs and their respective MOA, regulatory milestones, product development activities, advantages, disadvantages, safety, efficacy, etc.?
• How many companies are developing therapies for the treatment of Rotator Cuff Injuries?
• How many therapies are in-development by each company for Rotator Cuff Injuries treatment?
• How many are emerging therapies in mid-stage, and late stage of development for Rotator Cuff Injuries treatment?
• What are the key collaborations (Industry - Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Rotator Cuff Injuries therapies?
• What are the recent novel therapies, targets, mechanisms of action, and technologies being developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for Rotator Cuff Injuries and its status?
• What are the current challenges faced in drug development?
• What are the key designations that have been granted for the emerging therapies for Rotator Cuff Injuries?
• What are the global historical and forecasted markets of Rotator Cuff Injuries?

 

Reasons to buy

• The Patient Based Rotator Cuff Injuries Market Forecasting analysis report will help in developing business strategies by understanding trends shaping and driving the Rotator Cuff Injuries market
• Organize sales and marketing efforts by identifying the best opportunities for Rotator Cuff Injuries in the US, Europe (Germany, Spain, Italy, France) and the United Kingdom, and Japan
• Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
• Organize sales and marketing efforts by identifying the best opportunities for the Rotator Cuff Injuries market
• To understand the future market competition in the Rotator Cuff Injuries market