Sudden Sensorineural hearing loss Market

Key Highlights

 

• As per Thomas and Jeffrey (2013), the annual incidence of Sudden Sensorineural Hearing Loss was 27/100,000 in the United States. The incidence increased with increasing age, ranging from 11/100,000 for patients younger than 18 years to 77/100,000 for patients 65 years and older. There was an overall slight male preponderance with a male-to-female ratio of 1.07:1. This was more pronounced in patients 65 years and older, with a ratio of 1.30:1. As per the study, more than 66,000 new cases of Sudden Sensorineural Hearing Loss are seen annually in the United States. The disorder is more common in men and the elderly.

 

• Sudden Sensorineural Hearing Loss epidemiology is segmented as Total Incident Cases of Sudden Sensorineural Hearing Loss, Gender-specific Cases of Sudden Sensorineural Hearing Loss, Age-specific Cases of Sudden Sensorineural Hearing Loss, Severity-specific Cases of Sudden Sensorineural Hearing Loss, Nature-specific Cases of Sudden Sensorineural Hearing Loss, and Total Treated Cases of Sudden Sensorineural Hearing Loss] in the Sudden Sensorineural Hearing Loss market report.

 

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DelveInsight’s “Sudden Sensorineural Hearing Loss Market Insights, Epidemiology, and Market Forecast – 2032” report delivers an in-depth understanding of the Sudden Sensorineural Hearing Loss, historical and forecasted epidemiology as well as the Sudden Sensorineural Hearing Loss market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

 

The Sudden Sensorineural Hearing Loss market report provides current treatment practices, emerging drugs, Sudden Sensorineural Hearing Loss market share of the individual therapies, and current and forecasted Sudden Sensorineural Hearing Loss market size from 2019 to 2032, segmented by the seven major markets. The report also covers current Sudden Sensorineural Hearing Loss treatment practices/algorithms and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.

 

Geography Covered

• The United States
• EU4 (Germany, France, Italy, and Spain) and the United Kingdom
• Japan

 

Study period: 2019–2032

 

Sudden Sensorineural Hearing Loss Market: Understanding and Treatment Algorithm

DelveInsight’s Sudden Sensorineural Hearing Loss market report gives a thorough understanding of Sudden Sensorineural Hearing Loss by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis, and treatment.

 

Sudden Sensorineural Hearing Loss is defined as a sensorineural hearing loss of at least 30dB in 3 sequential frequencies with onset over 3 days or less. Although it has a high spontaneous recovery rate (32%-65%), the high incidence rate makes it a prevalent condition in many countries.

 

Although Sudden Sensorineural Hearing Loss can result from a variety of identifiable causes (neoplastic, infectious, autoimmune, neurologic, ototoxicity), 90% of cases are idiopathic in nature. The viral theory suggests Sudden Sensorineural Hearing Loss occurs when the cochlea or cochlear nerve is compromised by either an invading virus or reactivation of a latent neurotropic virus in the inner ear. Alternatively, a systemic viral infection can trigger an immune-mediated response or activation of the cellular stress pathway in the cochlea.

 

Sudden Sensorineural Hearing Loss can also be a consequence of impaired blood flow to the cochlea resulting from acute vascular hemorrhage, embolic occlusion, vascular disease, vasospasm, or hyperviscosity. Several autoimmune disorders, including cogan’s syndrome, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, and behçet syndrome can give rise to Sudden Sensorineural Hearing Loss.

 

Sudden Sensorineural Hearing Loss can be categorized into congenital and acquired sensorineural hearing loss. Congenital sensorineural hearing loss happens during pregnancy, some causes include prematurity, maternal diabetes, lack of oxygen during birth, genetics, and others. Whereas acquired sensorineural hearing loss occurs after birth and is speculative and probably multifactorial, various etiological theories have been proposed.

 

Sudden Sensorineural Hearing Loss is an emergency case that can lead to permanent hearing loss if not treated quickly and properly. Many patients with Sudden Sensorineural Hearing Loss have a history of a clear and sudden change in hearing or of awakening with new hearing loss, complaining of having a “blocked ear”. Many patients just think that they have an ear infection and don’t go to the doctor right away. These symptoms resemble those in patients with conductive hearing loss (CHL), making it crucial to differentiate between the two early on to ensure proper management. CHL is the most common type of hearing loss and involves problems affecting the external and middle ear, while Sudden Sensorineural Hearing Loss involves the inner ear. Tinnitus and dizziness are non-specific and may help to differentiate between CHL and Sudden Sensorineural Hearing Loss.

 

Sudden Sensorineural Hearing Loss Diagnosis

Tuning fork tests, audiograms, otoscopy, and thorough case history is essential in making a proper diagnosis of Sudden Sensorineural Hearing Loss. A crucial first step for physicians is to differentiate between Sudden Sensorineural Hearing Loss and other hearing issues. Due to the nature of Sudden Sensorineural Hearing Loss, patients most of the time have normal external auditory canals and tympanic membranes, resulting in a normal otoscopic exam.

 

Tuning fork tests, specifically the Weber and Rinne tests, can be used to differentiate between CHL and Sudden Sensorineural Hearing Loss. Although more time-consuming than tuning fork tests, standard pure tone audiometry is the most reliable method in differentiating between CHL and Sudden Sensorineural Hearing Loss. Pure tone audiometry contains diagnostic and prognostic values, capable of determining the degree and type of hearing loss.

 

Magnetic resonance imaging (MRI) with gadolinium contrast of the internal acoustic meatus and brain, coupled with cerebellopontine angles for tumors (specifically vestibular schwannomas and meningiomas) is used by many physicians to diagnose unilateral Sudden Sensorineural Hearing Loss. Auditory brainstem response testing (ABR) can be a useful alternative when MRI is not available or contraindicated. The sensitivity of ABR compared to MRI in diagnosing tumors is lower.

 

Sudden Sensorineural Hearing Loss Treatment

The mainstay treatment for idiopathic Sudden Sensorineural Hearing Loss is oral corticosteroids. The use of steroids should be tailored to the individual patient, and any comorbidities or risk factors taken into account and discussed with the patient. Even in diabetic patients, the individual risk-benefit analysis usually favors steroid use, with appropriate monitoring and management of diabetes.

 

Treatment with oral steroids is usually between 7–14 days, and tapering is not required with shorter courses. The guidelines suggest the use of intratympanic steroid injections should this initial therapy fail, as it may offer some hope as a salvage treatment if the response to systemic steroids is poor. Patients who do not respond to oral steroids should be referred early for consideration of intratympanic steroids.

 

Several other agents used to treat Sudden Sensorineural Hearing Loss due to other causes include anti-inflammatory agents, antimicrobials, calcium antagonists, vitamins, essential minerals, vasodilators, volume expanders, defibrinogenators, diuretics, and hyperbaric oxygen. Sudden Sensorineural Hearing Loss may be managed with hearing aids, when hearing aids are not enough, this type of hearing loss can be surgically treated with cochlear implants.

Sudden Sensorineural Hearing Loss Epidemiology

The Sudden Sensorineural Hearing Loss epidemiology section provides insights into the historical and current Sudden Sensorineural Hearing Loss patient pool and forecasted trends for the seven individual major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Sudden Sensorineural Hearing Loss report also provides the incident patient pool, their trends, and assumptions undertaken.

 

Key findings

 

• As per Thomas and Jeffrey (2013), the annual incidence of Sudden Sensorineural Hearing Loss was 27/100,000 in the United States. The incidence increased with increasing age, ranging from 11/100,000 for patients younger than 18 years to 77/100,000 for patients 65 years and older. There was an overall slight male preponderance with a male-to-female ratio of 1.07:1. This was more pronounced in patients 65 years and older, with a ratio of 1.30:1. As per the study, more than 66,000 new cases of Sudden Sensorineural Hearing Loss are seen annually in the United States. The disorder is more common in men and the elderly.

 

• The Sudden Sensorineural Hearing Loss epidemiology covered in the report provides historical as well as forecasted Sudden Sensorineural Hearing Loss epidemiology [segmented as Total Incident Cases of Sudden Sensorineural Hearing Loss, Gender-specific Cases of Sudden Sensorineural Hearing Loss, Age-specific Cases of Sudden Sensorineural Hearing Loss, Severity-specific Cases of Sudden Sensorineural Hearing Loss, Nature-specific Cases of Sudden Sensorineural Hearing Loss, and Total Treated Cases of Sudden Sensorineural Hearing Loss] in the 7MM covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2019 to 2032.

 

Country-wise Sudden Sensorineural Hearing Loss Epidemiology

The epidemiology segment also provides the Sudden Sensorineural Hearing Loss epidemiology data and findings across the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

 

Learn more about the evolving epidemiology trends and key developments: Sudden Sensorineural hearing loss (SSNHL) Epidemiology Forecast
 

Sudden Sensorineural Hearing Loss Drug Chapters

The drug chapter segment of the Sudden Sensorineural Hearing Loss report encloses a detailed analysis of Sudden Sensorineural Hearing Loss marketed drugs and late-stage (Phase III and Phase II) Sudden Sensorineural Hearing Loss pipeline drugs. It also helps understand the Sudden Sensorineural Hearing Loss clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

 

Emerging Sudden Sensorineural Hearing Loss drugs

The report details the emerging Sudden Sensorineural Hearing Loss therapies under the late and mid-stage of development for Sudden Sensorineural Hearing Loss treatment.

Sudden Sensorineural Hearing Loss Market Outlook

The Sudden Sensorineural Hearing Loss market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Sudden Sensorineural Hearing Loss market trends by analyzing the impact of current therapies on the market, unmet needs, and demand for better technology.

 

This segment gives a thorough detail of the Sudden Sensorineural Hearing Loss market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need for the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

 

According to DelveInsight, the Sudden Sensorineural Hearing Loss market in the 7MM is expected to witness a major change in the study period 2019–2032.

 

Key findings

This section includes a glimpse of the Sudden Sensorineural Hearing Loss market in the 7MM.

 

The United States: Sudden Sensorineural Hearing Loss Market Outlook

• This section provides the total Sudden Sensorineural Hearing Loss market size and market size by therapies in the United States.

 

EU4 and the United Kingdom: Sudden Sensorineural Hearing Loss Market Outlook

• The total Sudden Sensorineural Hearing Loss market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.

 

Japan: Sudden Sensorineural Hearing Loss Market Outlook

• The total Sudden Sensorineural Hearing Loss market size and market size by therapies in Japan are also mentioned.

Sudden Sensorineural Hearing Loss Drug Uptake

This section focuses on the rate of uptake of the potential drugs recently launched in the Sudden Sensorineural Hearing Loss market or expected to get launched in the market during the study period 2019–2032. The analysis covers the Sudden Sensorineural Hearing Loss market uptake by drugs, patient uptake by therapies, and sales of each drug. 

 

This will help in understanding the Sudden Sensorineural Hearing Loss drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on market share and size, which again will be useful in investigating factors important in the market uptake and in making financial and regulatory decisions.

 

Sudden Sensorineural Hearing Loss Pipeline Development Activities

The report provides insights into different therapeutic candidates in the Phase II, and Phase III stages. It also analyses Sudden Sensorineural Hearing Loss’s key players involved in developing targeted therapeutics.

 

Sudden Sensorineural Hearing Loss Clinical Trial Development Activities

The report covers detailed information on collaborations, acquisitions, and mergers, licensing patent details, and other information for Sudden Sensorineural Hearing Loss emerging therapies.

 

Sudden Sensorineural Hearing Loss Reimbursement Scenario

Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

 

Learn more about the emerging therapies and key companies active in the therapeutics segment: Sudden Sensorineural hearing loss (SSNHL) Pipeline Insight
 

KOL Views

To keep up with current epidemiology and market trends, we take KOLs and SMEs' opinions working in the Sudden Sensorineural Hearing Loss domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies and treatment patterns along with Sudden Sensorineural Hearing Loss market trends. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the market and the unmet needs.

 

Competitive Intelligence Analysis

We perform competitive and market intelligence analysis of the Sudden Sensorineural Hearing Loss market by using various competitive intelligence tools that include – SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.

 

Scope of the Sudden Sensorineural Hearing Loss Market Report

• Descriptive overview of Sudden Sensorineural Hearing Loss, disease overview, patient journeys, treatment algorithms, diagnosis, and currently available therapies
• Comprehensive insight into the Sudden Sensorineural Hearing Loss epidemiology and forecasts in the 7MM
• An all-inclusive account of both the current and emerging therapies for Sudden Sensorineural Hearing Loss, along with the assessment of new therapies, expected to have an impact on the current treatment landscape
• Exhaustive analysis of the Sudden Sensorineural Hearing Loss market; historical and forecasted covering drug outreach in the 7MM
• Detailed Patient Based Market Forecasting determines the trends shaping and driving the global Sudden Sensorineural Hearing Loss market

 

Sudden Sensorineural Hearing Loss Market Report Highlights

• In the coming years, the Sudden Sensorineural Hearing Loss market is set to change due to the rising awareness of the disease and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
• The companies and academics are working to assess challenges and seek opportunities that could influence Sudden Sensorineural Hearing Loss R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition  
• Major players are involved in developing Sudden Sensorineural Hearing Loss therapies. The launch of emerging therapies will significantly impact the Sudden Sensorineural Hearing Loss market
• A better understanding of Sudden Sensorineural Hearing Loss pathogenesis will also contribute to the development of novel therapeutics for Sudden Sensorineural Hearing Loss
• Our in-depth analysis of the Sudden Sensorineural Hearing Loss pipeline assets across different stages of development (Phase III and Phase II), emerging trends, and comparative analysis of pipeline products with detailed Sudden Sensorineural Hearing Loss clinical trial profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

 

Sudden Sensorineural Hearing Loss Report Insights

• Patient Based Market Forecasting
• Therapeutic approaches
• Sudden Sensorineural Hearing Loss pipeline analysis
• Sudden Sensorineural Hearing Loss market size and trends
• Sudden Sensorineural Hearing Loss market opportunities
• Impact of upcoming therapies

 

Sudden Sensorineural Hearing Loss Report Key Strengths

• 11 years forecast
• The 7MM Coverage
• Sudden Sensorineural Hearing Loss epidemiology segmentation
• Key cross competition
• KOL views
• Sudden Sensorineural Hearing Loss drugs uptake

 

Sudden Sensorineural Hearing Loss Report Assessment

• Current treatment practices
• Unmet needs
• Sudden Sensorineural Hearing Loss pipeline product profiles
• Sudden Sensorineural Hearing Loss market attractiveness

 

Key Questions

• Sudden Sensorineural Hearing Loss market insights:
• What would be the Sudden Sensorineural Hearing Loss market growth till 2032, and what will be the resultant market size in 2032?
• What was the Sudden Sensorineural Hearing Loss drug class share (in percentage) distribution in 2019, and how would it look in 2032?
• What would be the Sudden Sensorineural Hearing Loss total market size and market size by therapies across the 7MM during the forecast period (2022–2032)?
• What are the key findings of the market across the 7MM, and which country will have the largest Sudden Sensorineural Hearing Loss market size during the forecast period (2022–2032)
• How would the unmet needs affect the Sudden Sensorineural Hearing Loss market dynamics and subsequent analysis of the associated trends?

 

Sudden Sensorineural Hearing Loss Epidemiology Insights:

• What are the disease risk, burden, and regional/ethnic differences of Sudden Sensorineural Hearing Loss?
• What is the historical and forecasted Sudden Sensorineural Hearing Loss patient pool in the 7MM, and where can one observe the highest patient population and growth opportunities?
• What are the key factors driving the epidemiology trends for the seven major markets covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan?
• ent Treatment Scenario, Marketed Drugs, and Emerging Therapies
• What are the current treatment guidelines and treatment options, in addition to approved therapies for Sudden Sensorineural Hearing Loss in the United States, Europe, and Japan?
• What are the key collaborations (Industry–Industry, Industry-Academia), mergers and acquisitions, and licensing activities related to Sudden Sensorineural Hearing Loss therapies?
• What are the recent novel therapies, targets, mechanisms of action, and technologies being developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for Sudden Sensorineural Hearing Loss and its status, along with the challenges faced?

 

Reasons to Buy

• The Patient Based Market Forecasting analysis will help in developing business strategies by understanding trends shaping and driving the Sudden Sensorineural Hearing Loss market
• Organize sales and marketing efforts by identifying the best opportunities for Sudden Sensorineural Hearing Loss in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan
• Identification of strong upcoming players in the market that will help devise strategies that will help in getting ahead of competitors.