Surgical Site Infection Ssi Epidemiology Forecast Insight

DelveInsight’s ‘Surgical site infection (SSI)–Epidemiology Forecast—2030’ report delivers an in-depth understanding of the Surgical site infection (SSI), historical and forecasted epidemiology in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom) and Japan.

Geographies Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study Period: 2018–2030

Surgical site infection (SSI) Disease Understanding

Surgical Site infections (SSI) are the infections following an invasive surgical procedure and are the most frequently reported hospital-acquired infections (HAI). SSI is a type of hospital-acquired infection (HAI) that arises following surgery and it is related to the surgical site. Currently, SSI is defined as an infection that happens within 30 days of the operation if no implant is left in place or within a year of operation if an implant is left in place.


The United States Centers for Disease Control and Prevention (CDC) has developed a definition for SSI as an “infection related to an operative procedure that occurs at or near the surgical incision within 30 days of the procedure or within 90 days if prosthetic material is implanted at surgery.”


According to the Centers for Disease Control and Prevention [CDC], a surgical site infection (SSI) is an infection that occurs after surgery in the part of the body where the surgery took place. Surgical site infections can sometimes be superficial infections involving the skin only. Other surgical site infections are more serious and can involve tissues under the skin, organs, or implanted material.


The most common types of inpatient surgical procedures include cesarean section, orthopedic procedures (hip and knee replacement, hip fracture repair), neurosurgical procedures (spinal fusion and laminectomy), and intraabdominal procedures (cholecystectomy and colorectal resections). Increasing numbers of patients also undergo surgery at ambulatory surgery centers (facilities specifically designed for certain types of surgery after which the patient can be discharged home directly).


SSIs occur in a very few percentage of the patients undergoing inpatient surgical procedures. Although most infections are treatable with antibiotics, SSIs remain a significant cause of morbidity and mortality after surgery. They are the leading cause of readmissions to the hospital following surgery and a few patients who contract an SSI die as a consequence.

Surgical site infection (SSI) Epidemiology

The Surgical site infection (SSI) epidemiology division provides insights about the historical and current patient pool along with the forecasted trend for every seven major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.


Key Findings

The disease epidemiology covered in the report provides historical as well as forecasted surgical site infection (SSI) epidemiology segmented as the Total Surgical Procedures, Number of Surgical Procedures by Type, Total Incident cases of Surgical Site Infections (SSI) and Incidence of Surgical Site Infections (SSI) by Type. The report includes the Incident scenario of Surgical site infection (SSI) symptoms in 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2018 to 2030.

Country-wise Surgical site infection (SSI) Epidemiology

The epidemiology segment also provides the Surgical site infection (SSI) epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.


The total Incident population of Surgical site infection (SSI) Associated in 7MM countries was estimated to be 1,275,912 cases in 2020 and expected to decline at a CAGR of −5.11% for the study period, i.e., 2018–2030.

  • As per the estimates, the US has the highest Incident population of Surgical site infection (SSI)
  • Among the EU5 countries, UK had the highest Incident population of surgical site infection (SSI). On the other hand, Italy had the lowest number of cases, as 61,942 cases in 2020.

Scope of the Report

  • Surgical site infection (SSI) report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis, and treatment patterns
  • Surgical site infection (SSI) Epidemiology Report and Model provide an overview of the risk factors and global trends of Surgical site infection (SSI) in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan)
  • The report provides insight into the historical and forecasted patient pool of Surgical site infection (SSI) in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan
  • The report helps recognize the growth opportunities in the 7MM concerning the patient population
  • The report assesses the disease risk and burden and highlights the unmet needs of Surgical site infection (SSI)
  • The report provides the segmentation of the Surgical site infection (SSI) epidemiology by Incident Cases of Surgical site infection (SSI) in 7MM
  • The report provides the segmentation of the Surgical site infection (SSI) epidemiology by Type-specific Incident Cases of Surgical site infection (SSI) in 7MM

Report Highlights

  • 10-year Forecast of Surgical site infection (SSI) epidemiology
  • 7MM Coverage
  • Total Incident Cases of Surgical site infection (SSI)
  • Incident Cases according to segmentation: Type-specific Incidence of Surgical site infection (SSI)

KOL Views

We interview KOLs, and SME’s opinion through primary research to fill the data gaps and validate our secondary research. The opinion helps understand the total patient population and current treatment pattern. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the indications.

Key Questions Answered

  • What will be the growth opportunities in the 7MM concerning the patient population about surgical site infection (SSI)?
  • What are the key findings of surgical site infection (SSI) epidemiology across 7MM, and which country will have the highest number of patients during the forecast period (2018–2030)?
  • What would be the total number of patients with surgical site infection (SSI) across the 7MM during the forecast period (2018–2030)?
  • Among the EU5 countries, which country will have the highest number of patients during the forecast period (2018–2030)?
  • At what CAGR the patient population is expected to grow by 7MM during the forecast period (2018–2030)?
  • What are the disease risk, burden, and unmet needs of surgical site infection (SSI)?
  • What are the currently available treatments for surgical site infection (SSI)?

Reasons to buy

The Surgical site infection (SSI) Epidemiology report will allow the user to -

  • Develop business strategies by understanding the trends shaping and driving the global Surgical site infection (SSI) market
  • Quantify patient populations in the global Surgical site infection (SSI) market to improve product design, pricing, and launch plans
  • Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for Surgical site infection (SSI) therapeutics in each of the markets covered
  • Understand the magnitude of Surgical site infection (SSI) population by its Incidence cases
  • Understand the magnitude of Surgical site infection (SSI) population by its Type-specific cases
  • The Surgical site infection (SSI) epidemiology report and model was written and developed by Masters and PhD level epidemiologists
  • The Surgical site infection (SSI) Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources

Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of disease by the segmentation
  • Factors driving growth in a specific patient population

1. Key Insights

2. Report Introduction

3. Executive Summary of Surgical Site Infection

4. Disease Background and Overview

4.1. Introduction

4.2. Types

4.3. Signs and Symptoms

4.4. Causes

4.5. Risk Factors

4.5.1. Assessing Patient Risks during the Preoperative Phase

4.5.2. Modifiable and Non-Modifiable Host Risk Factors

4.5.3. Extrinsic or External Risk Factors

4.6. Pathogenesis

4.7. Diagnosis

4.7.1. Diagnosis Based on Types

4.7.2. Diagnosis Based on Microbes

5. Epidemiology and Patient Population

5.1. Key Findings

5.2. 7MM Total Patient Population of Surgical Site Infection

5.3. The United States

5.3.1. Assumptions and Rationale

5.3.2. Total Surgical Procedures in the United States

5.3.3. Number of surgical procedures by types in the United States

5.3.4. Total Incident cases of Surgical Site Infections in the United States

5.3.5. Incidence of Surgical Site Infections by types in the United States

5.4. EU5

5.4.1. Assumtions and Rationale

5.4.2. Germany

5.4.2.1. Total Surgical Procedures in Germany

5.4.2.2. Number of surgical procedures by types in Germany

5.4.2.3. Total Incident cases of Surgical Site Infections in Germany

5.4.2.4. Incidence of Surgical Site Infections by types in Germany

5.4.3. France

5.4.3.1. Total Surgical Procedures of Surgical Site Infection in France

5.4.3.2. Number of surgical procedures by types in France

5.4.3.3. Total Incident cases of Surgical Site Infections in France

5.4.3.4. Incidence of Surgical Site Infections by types in France

5.4.4. Italy

5.4.4.1. Total Surgical Procedures in Italy

5.4.4.2. Number of surgical procedures by types in Italy

5.4.4.3. Total Incident cases of Surgical Site Infections in Italy

5.4.4.4. Incidence of Surgical Site Infections by types in Italy

5.4.5. Spain

5.4.5.1. Total Surgical Procedures in Spain

5.4.5.2. Number of surgical procedures by types in Spain

5.4.5.3. Total Incident cases of Surgical Site Infections in Spain

5.4.5.4. Incidence of Surgical Site Infections by types in Spain

5.4.6. United Kingdom

5.4.6.1. Total Surgical Procedures in the United Kingdom

5.4.6.2. Number of surgical procedures by types in the United Kingdom

5.4.6.3. Total Incident cases of Surgical Site Infections in the United Kingdom

5.4.6.4. Incidence of Surgical Site Infections by types in the United Kingdom

5.5. Japan

5.5.1. Assumptions and Rationale

5.5.2. Total Surgical Procedures in Japan

5.5.3. Number of surgical procedures by types in Japan

5.5.4. Total Incident cases of Surgical Site Infections in Japan

5.5.5. Incidence of Surgical Site Infections by types in Japan

6. Treatment and Management

6.1. Treatment Algorithm of Surgical Site Infections (SSIs)

7. Prevention

7.1. Preoperative Measures

7.2. Intraoperative Measures

7.3. Postoperative Measures

7.4. Antibiotic Prophylaxis (AP)

7.5. Prevention Guideline for Surgical Site Infections (SSIs)

7.5.1. Centers for Disease (CDC): Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017

7.5.2. World Health Organization (WHO): Global Guidelines for the Prevention of Surgical Site Infection

7.5.3. National Institute for Health and Care Excellence (NICE): Surgical Site Infections: Prevention and Treatment Guidelines

8. Appendix

8.1. Bibliography

8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

List of Table

Table 1: Summary of Surgical Site Infection, Market, Epidemiology, and Key Events (2018–2030)

Table 2: Summary of treatment market size of SSI (2018–2030)

Table 3: Types of Surgical Site Infections (SSIs)

Table 4: Pathogens commonly associated with Different Surgical Procedures

Table 5: Host (Intrinsic or Internal) Characteristics in Surgical Patients

Table 6: Types of Surgical Site Infections (SSIs)

Table 7: Total Patient Population of Surgical Site Infection in thousands in 7MM (2018–2030)

Table 8: Total Surgical Procedures in the United States (2018–2030)

Table 9: Number of surgical procedures by types in thousands in the United States (2018–2030)

Table 10: Total Incidence cases of Surgical Site Infections in the United States (2018–2030)

Table 11: Incidence of Surgical Site Infection by types in the United States (2018–2030)

Table 12: Total Surgical Procedures in thousands in Germany (2018–2030)

Table 13: Number of surgical procedures by types in Germany (2018–2030)

Table 14: Total Incidence cases of Surgical Site Infections in Germany (2018–2030)

Table 15: Incidence of Surgical Site Infection by types in Germany (2018–2030)

Table 16: Total Surgical Procedures in thousands in France (2018–2030)

Table 17: Number of surgical procedures by types in thousands in France (2018–2030)

Table 18: Total Incident cases of Surgical Site Infections in France (2018–2030)

Table 19: Incidence of Surgical Site Infections by types in France (2018–2030)

Table 20: Total Surgical Procedures in thousands in Italy (2018–2030)

Table 21: Number of surgical procedures by types in thousands in Italy (2018–2030)

Table 22: Total Incident cases of Surgical Site Infections in Italy (2018–2030)

Table 23: Incidence of Surgical Site Infection by types in Italy (2018–2030)

Table 24: Total Surgical Procedures in thousands in Spain (2018–2030)

Table 25: Number of surgical procedures by types in thousands in Spain (2018–2030)

Table 26: Total Incident cases of Surgical Site Infections in Spain (2018–2030)

Table 27: Incidence of Surgical Site Infections by types in Spain (2018–2030)

Table 28: Total Surgical Procedures in thousands in the United Kingdom (2018–2030)

Table 29: Number of surgical procedures by types in thousands in the United Kingdom (2018–2030)

Table 30: Total Incident cases of Surgical Site Infections in the United Kingdom (2018–2030)

Table 31: Incidence of Surgical Site Infections by types in the United Kingdom (2018–2030)

Table 32: Total Surgical Procedures in thousands in Japan (2018–2030)

Table 33: Number of surgical procedures by types in thousands in Japan (2018–2030)

Table 34: Total Incident cases of Surgical Site Infections in Japan (2018–2030)

Table 35: Incidence of Surgical Site Infections by types in Japan (2018–2030)

Table 36: Surgical Site Infection (SSI) Treatment Algorithm

Table 37: Most Commonly Prescribed Agents for Patients Who Received Any Antimicrobial or Combination of Antimicrobials Consistent with Surgical Antimicrobial Prophylaxis Guidelines*

Table 38: Summary of core topics, research questions and recommendations for the prevention of surgical site infection.

Table 39: Options for Antiseptic Skin Preparation

List of Figures

Figure 1: Total Patient Population of Surgical Site Infection in thousands in 7MM (2018–2030)

Figure 2: Total Surgical Procedures in thousands in the United States (2018–2030)

Figure 3: Number of surgical procedures by types in thousands in the United States (2018–2030)

Figure 4: Total Incident cases of Surgical Site Infections in the United States (2018–2030)

Figure 5: Incidence of Surgical Site Infection by types in the United States (2018–2030)

Figure 6: Total Surgical Procedures in thousands in Germany (2018–2030)

Figure 7: Number of surgical procedures by types in thousands in Germany (2018–2030)

Figure 8: Total Incident cases of Surgical Site Infections in Germany (2018–2030)

Figure 9: Incidence of Surgical Site Infection by types in Germany (2018–2030)

Figure 10: Total Surgical Procedures in thousands in France (2018–2030)

Figure 11: Number of surgical procedures by types in thousands in France (2018–2030)

Figure 12: Total Incident cases of Surgical Site Infections in France (2018–2030)

Figure 13: Incidence of Surgical Site Infections by types in France (2018–2030)

Figure 14: Total Surgical Procedures in thousands in Italy (2018–2030)

Figure 15: Number of surgical procedures by types in thousands in Italy (2018–2030)

Figure 16: Total Incident cases of Surgical Site Infections in Italy (2018–2030)

Figure 17: Incidence of Surgical Site Infections by types in Italy (2018–2030)

Figure 18: Total Surgical Procedures in thousands in Spain (2018–2030)

Figure 19: Number of surgical procedures by types in thousands in Spain (2018–2030)

Figure 20: Total Incident cases of Surgical Site Infections in Spain (2018–2030)

Figure 21: Incidence of Surgical Site Infections by types in Spain (2018–2030)

Figure 22: Total Surgical Procedures in thousands in the United Kingdom (2018–2030)

Figure 23: Number of surgical procedures by types in thousands in the United Kingdom (2018–2030)

Figure 24: Total Incident cases of Surgical Site Infections in the United Kingdom (2018–2030)

Figure 25: Incidence of Surgical Site Infections by types in the United Kingdom (2018–2030)

Figure 26: Total Surgical Procedures in thousands in Japan (2018–2030)

Figure 27: Number of surgical procedures by types in thousands in Japan (2018–2030)

Figure 28: Total Incident cases of Surgical Site Infections in Japan (2018–2030)

Figure 29: Incidence of Surgical Site Infections by types in Japan (2018–2030)

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