The U.S. government’s revival of the Most-Favored-Nation (MFN) model and proposed tariffs of up to 250% represent one of the most disruptive policy shifts in pharmaceutical history. With $200–300B in annual revenues at risk, the coming months will determine winners and losers across oncology, autoimmune, diabetes, and rare disease markets.
In our in-depth analysis, you’ll uncover:
The real numbers behind the MFN mandate and its global ripple effects
Which companies and blockbuster drugs are most exposed
The strategic pivots pharma leaders are deploying to navigate uncertainty
How these policies could reshape R&D, innovation, and global pricing power
With a September 29, 2025 compliance deadline approaching, pharmaceutical leaders face a pivotal moment. The ripple effects extend well beyond the U.S., putting global supply chains, launch sequencing, and R&D pipelines under direct pressure.
Executives who act with foresight can mitigate risk, protect shareholder value, and seize competitive advantage in this volatile landscape.
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