Allergic Rhinitis Epidemiology Forecast Insight

DelveInsight’s ‘Allergic Rhinitis - Epidemiology Forecast to 2030’ report delivers an in-depth understanding of the disease, historical and forecasted Allergic Rhinitis epidemiology in the 7MM, i.e., the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

Geographies Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study Period: 2018–2030

Allergic Rhinitis Understanding

Allergic Rhinitis is a condition that occurs when the body (the immune system) overreacts to something in the environment (triggers). It is caused by allergens, which are usually harmless substances but trigger an allergic reaction in some people. When the symptoms occur in late summer or early fall, some people call it hay fever. Those with rhinitis are prone to symptoms such as runny nose, sneezing, congestion, and sinus pressure. In addition, rhinitis can contribute to other problems such as asthma, sinus or ear conditions, or trouble sleeping.

 

Rhinitis is one of the most common chronic conditions for which medical care is sought. Allergic rhinitis is an IgE-mediated disorder of the nose caused by the interaction of airborne allergens with specific IgE-type antibodies on the surface of mast cells. The IgE-allergen interaction leads to the mast cell releasing and synthesizing several chemicals, which then cause the surrounding tissues to become inflamed. Typical initial symptoms include rhinorrhea, nasal itching, sneezing, and nasal congestion, although extranasal symptoms such as allergic conjunctivitis, itchy ears and palate, and asthma are commonly associated as well. A positive correlation between the clinical history and allergen sensitization is usually enough to support the diagnosis of allergic rhinitis.

 

Allergic Rhinitis can last several weeks, longer than a cold or the flu. It does not cause fever, and the nasal discharge from hay fever is thin, watery, and clear, whereas nasal discharge from a cold or the flu tends to be thicker. Itching (mostly in the eyes, nose, mouth, throat, and skin) is common with allergic rhinitis but not with a cold or the flu. Sneezing occurs more with allergic rhinitis, and patients may even have severe sneeze attacks.

 

Allergic Rhinitis is increasing worldwide, and environmental impact on disease is evident; some populations tend to be affected more and have the more severe clinical presentation of allergic disease. Thus, genetic studies are important in understanding the pathology of the disease. Monozygotic twins demonstrate concordance of 45–60% in the development of allergic rhinitis, and dizygotic twins have a concordance rate of 25%. Chromosome 3 has three regions linked to allergic rhinitis, 3q13, 3q13.31, and 3p24. A possible involved region on chromosome 4 is 4q24-q27.

 

Allergic Rhinitis Diagnosis

Allergic rhinitis is often under-recognized owing to poor public awareness, limited access to allergologists, and confounding diagnoses, such as the common cold. Its diagnosis is made by considering a detailed history that is supported by examination findings (physical examination and, if needed, nasal endoscopy) and, if necessary, testing for allergen-specific IgE. Other tests such as nasal allergen challenge, CT scans, evaluation of nasal nitric oxide and ciliary beat frequency, nasal smears, nasal cultures, and analysis of nasal fluid for β-transferrin) may be required to include or exclude different forms of rhinitis.

 

The most common diagnostic tests for allergic rhinitis are the percutaneous skin test and the allergen-specific immunoglobulin E (IgE) antibody test. Less common diagnostic tools include nasal provocation testing, nasal cytology (e.g., blown secretions, scraping, lavage, and biopsy), nasolaryngoscopy, and intradermal skin testing. The WHO report offers limited recommendations on when to use these tests but notes that they generally are used by subspecialists or in research and do not play a role in the routine evaluation of allergic rhinitis.

Epidemiology Perspective by DelveInsight

The Allergic Rhinitis epidemiology division provides insights about historical and current Allergic Rhinitis patient pool and forecasted trends for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

 

Key Findings

In the year 2020, the total prevalent cases of Allergic Rhinitis was 188.40 million cases in the 7MM which are expected to grow during the study period, i.e., 2018–2030.

 

The disease epidemiology covered in the report provides historical as well as forecasted Allergic Rhinitis epidemiology [segmented as Total Prevalent Cases of Allergic Rhinitis, Total Diagnosed Cases of Allergic Rhinitis, Total Age group-specific Cases of Allergic Rhinitis, Total Allergen-specific Cases of Allergic Rhinitis, and Total Treated Cases of Allergic Rhinitis] in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2018 to 2030.

Country Wise- Allergic Rhinitis Epidemiology

  • Estimates show that the highest cases of Allergic Rhinitis in the 7MM were in Japan, followed by the United States, Germany, France, the United Kingdom, Italy, and Spain in 2020.
  • In the United States, the total number of prevalent cases of Allergic Rhinitis was 52.26 million cases in the year 2020 which are expected to grow during the study period, i.e., 2018–2030.
  • In the year 2020, the total prevalent cases of Allergic Rhinitis were 76.86 million cases in EU-5 which are expected to grow during the study period, i.e., 2018–2030.
  • In Japan, the total number of prevalent cases of Allergic Rhinitis was 59.29 million cases in the year 2020 which are expected to grow during the study period, i.e., 2018–2030.

Scope of the Report

  • The Allergic Rhinitis report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis, and treatment patterns.
  • The Allergic Rhinitis Report and Model provide an overview of the risk factors and global trends of Allergic Rhinitis in the seven major markets (7MM: The United States, Germany, France, Italy, Spain, the United Kingdom, and Japan)
  • The report provides insight about the historical and forecasted patient pool of Allergic Rhinitis in seven major markets covering the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
  • The report helps to recognize the growth opportunities in the 7MM concerning the patient population.
  • The report assesses the disease risk and burden and highlights the unmet needs of Allergic Rhinitis.
  • The report provides the segmentation of the Allergic Rhinitis epidemiology by total prevalent cases in the 7MM.
  • The report provides the segmentation of the Allergic Rhinitis epidemiology by total diagnosed cases in the 7MM.
  • The report provides the segmentation of the Allergic Rhinitis epidemiology by total age group-specific cases in the 7MM.
  • The report provides the segmentation of the Allergic Rhinitis epidemiology by total allergen-specific cases in the 7MM.
  • The report provides the segmentation of the Allergic Rhinitis epidemiology by total treated cases in the 7MM.

Report Highlights

  • 10-Year Forecast of Allergic Rhinitis epidemiology
  • 7MM Coverage
  • Total Prevalent Cases of Allergic Rhinitis
  • Total Diagnosed Cases of Allergic Rhinitis
  • Total Age group-Specific Cases of Allergic Rhinitis
  • Total Allergen-Specific Cases of Allergic Rhinitis
  • Total Treated Cases of Allergic Rhinitis

KOL-Views

We interview KOL’s and SME's opinion through primary research to fill the data gaps and validate our secondary research. The opinion helps to understand the total patient population and current treatment pattern. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the indications.

Key Questions Answered

  • What will be the growth opportunities in the 7MM concerning the patient population of Allergic Rhinitis?
  • What are the key findings of the Allergic Rhinitis epidemiology across the 7MM and which country will have the highest number of patients during the study period (2018–2030)?
  • What would be the total number of patients of Allergic Rhinitis across the 7MM during the study period (2018–2030)?
  • Among the EU5 countries, which country will have the highest number of patients during the study period (2018–2030)?
  • At what CAGR the patient population is expected to grow in the 7MM during the study period (2018–2030)?
  • What are the various recent and upcoming events which are expected to improve the diagnosis of Allergic Rhinitis?

Reasons to buy

The Allergic Rhinitis Epidemiology report will allow the user to -

  • Develop business strategies by understanding the trends shaping and driving the global Allergic Rhinitis market
  • Quantify patient populations in the global Allergic Rhinitis market to improve product design, pricing, and launch plans
  • Organize sales and marketing efforts by identifying the gender that presents the best opportunities for Allergic Rhinitis therapeutics in each of the markets covered
  • Understand the magnitude of Allergic Rhinitis population by its age group-specificity
  • The Allergic Rhinitis epidemiology report and model were written and developed by Masters and Ph.D. level epidemiologists
  • The Allergic Rhinitis Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over an 10-year forecast period using reputable sources

Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of disease by the segmentation
  • Factors driving growth in a specific patient population

1. Key Insights

2. Report Introduction

3. Executive Summary of Allergic rhinitis

3.1. Key Events

4. Epidemiology Methodology

5. Disease Background and Overview

5.1. Introduction

5.2. Types of Allergic Rhinitis

5.3. Signs and Symptoms of Allergic Rhinitis

5.4. Risk Factors and Causes of Allergic rhinitis

5.5. Pathogenesis of Allergic rhinitis

5.6. Genetics of Allergic rhinitis

5.7. Complications of Allergic rhinitis

6. Diagnosis of Allergic rhinitis

6.1. Diagnostic Algorithm of Allergic rhinitis

6.2. Detailed History from the patient

6.3. Skin Test

6.4. IgE Antibody Test

6.5. Nasal Allergen Challenges (NAC)

6.6. Differential Diagnosis of Allergic Rhinitis

6.7. Diagnosis Guidelines of Allergic Rhinitis

6.7.1. American Academy of Otolaryngology–Head and Neck Surgery (2015)

6.7.2. Rhinitis 2020: A Practice Parameter

7. Conclusion

8. Epidemiology and Patient Population

8.1. Key Findings

8.2. Epidemiology of Allergic Rhinitis

8.3. Epidemiology Scenario

8.3.1. Total Prevalent Cases of Allergic Rhinitis

8.3.2. Total Diagnosed Cases of Allergic Rhinitis

8.3.3. Total Age group-specific Cases of Allergic Rhinitis

8.3.4. Total Allergen-specific Cases of Allergic Rhinitis

8.3.5. Total Treated Cases of Allergic Rhinitis

9. KOL Views

10. Appendix

10.1. Bibliography

10.2. Report Methodology

11. DelveInsight Capabilities

12. Disclaimer

13. About DelveInsight

List of Table

Table 1: Summary of Allergic rhinitis, Market, Epidemiology, and Key Events (2018–2030)

Table 2: Total Prevalent Cases of Allergic Rhinitis (in Millions) in the 7MM (2018–2030)

Table 3: Total Diagnosed Cases of Allergic Rhinitis (in Millions) in the 7MM (2018–2030)

Table 4: Total Age group-specific Cases of Allergic Rhinitis (in Millions) in the 7MM (2018–2030)

Table 5: Total Allergen-specific Cases of Allergic Rhinitis (in Millions) in the 7MM (2018–2030)

Table 6: Total Treated Cases of Allergic Rhinitis (in Millions) in the 7MM (2018–2030)

List of Figures

Figure 1: Epidemiology and Market Methodology

Figure 2: Understanding of Allergic rhinitis

Figure 3: Classification of Allergic rhinitis

Figure 4: Types of Allergic rhinitis

Figure 5: Sign and Symptoms of Allergic rhinitis

Figure 6: Causes of Allergic rhinitis

Figure 7: Pathogenesis of Allergic rhinitis

Figure 8: Complications of Allergic rhinitis

Figure 9: Diagnostic Algorithm of Allergic rhinitis

Figure 10: Skin Prick Test

Figure 11: Nasal Allergen Challenges (NAC)

Figure 12: Treatment Algorithm of Allergic rhinitis

Figure 13: Intranasal steroids

Figure 14: Sublingual and Subcutaneous Immunotherapy

Figure 15: Recommendations for Adding a Second Medication to Treat Allergic rhinitis

Figure 16: Total Prevalent Cases of Allergic Rhinitis in the 7MM (2018–2030)

Figure 17: Total Diagnosed Cases of Allergic Rhinitis in the 7MM (2018–2030)

Figure 18: Total Allergen-specific Cases of Allergic Rhinitis in the 7MM (2018–2030)

Figure 19: Total Treated Cases of Allergic Rhinitis in the 7MM (2018–2030)

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