Aplastic Anemia Pipeline Insight
DelveInsight’s, “Aplastic Anemia - Pipeline Insight, 2022,” report provides comprehensive insights about 8+ companies and 8+ pipeline drugs in Aplastic Anemia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
- Global coverage
Aplastic Anemia Understanding
Aplastic Anemia: Overview
Aplastic anemia is a medical condition that damages stem cells in a person’s bone marrow. These cells are responsible for making red blood cells, white blood cells, and platelets, which are vital to human health. A rare and serious condition, aplastic anemia can develop at any age. It can occur suddenly, or it can come on slowly and worsen over time. It can be mild or severe. Treatment for aplastic anemia might include medications, blood transfusions or a stem cell transplant, also known as a bone marrow transplant. The most common cause of aplastic anemia is from your immune system attacking the stem cells in your bone marrow. Other factors that can injure bone marrow and affect blood cell production include: Radiation and chemotherapy treatments, exposure to toxic chemicals, use of certain drugs, autoimmune disorders, a viral infection and unknown factors.
"Aplastic Anemia - Pipeline Insight, 2022" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Aplastic Anemia pipeline landscape is provided which includes the disease overview and Aplastic Anemia treatment guidelines. The assessment part of the report embraces, in depth Aplastic Anemia commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Aplastic Anemia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence Aplastic Anemia R&D. The therapies under development are focused on novel approaches for Aplastic Anemia.
Aplastic Anemia Emerging Drugs Chapters
This segment of the Aplastic Anemia report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Aplastic Anemia Emerging Drugs
PF-06462700: Pfizer
PF-06462700 is classified as an immunosuppressant/ immunosuppressive agent. It is the purified, concentrated, and sterile gamma globulin, primarily monomeric immunoglobulin G (IgG), from hyperimmune serum of horses that are immunized with human thymus lymphocytes. PF-06462700 is being developed by Pfizer for Aplastic anaemia and is currently in phase III stage of development.
REGN7257: Regeneron Pharmaceuticals
REGN7257is being developed by Regeneron Pharmaceuticals for Aplastic Anemia. It is currently in phase I/II stage of development. LB-001 acts as a modulator of Interleukin 2 and immunomodular.
BL-8040: BioLineRx, Ltd.
BL-8040 (Motixafortide) targets CXCR4, a chemokine receptor and a well-validated therapeutic target that is over-expressed in many human cancers, including PDAC. CXCR4 plays a key role in tumor growth, invasion, angiogenesis, metastasis, therapeutic resistance, and CXCR4 overexpression correlated with poor prognosis. A Phase II clinical trial has been completed for BL-8040 for the treatment of Aplastic Anemia.
Further product details are provided in the report……..
Aplastic Anemia: Therapeutic Assessment
This segment of the report provides insights about the different Aplastic Anemia drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players working on Aplastic Anemia
There are approx. 8+ key companies which are developing the Aplastic Anemia. The companies which have their Aplastic Anemia drug candidates in the most advanced stage, i.e. Phase III include, Pfizer.
Phases
DelveInsight’s report covers around 8+ products under different phases of clinical development like
- Late-stage products (Phase III and
- Mid-stage products (Phase II and
- Early-stage products (Phase I/II and Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
Aplastic Anemia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Infusion
- Intradermal
- Intramuscular
- Intranasal
- Intravaginal
- Oral
- Parenteral
- Subcutaneous
- Topical
- Molecule Type
Products have been categorized under various Molecule types such as
- Vaccines
- Monoclonal Antibody
- Peptides
- Polymer
- Small molecule
- Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Aplastic Anemia: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Aplastic Anemia therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Aplastic Anemia drugs.
Aplastic Anemia Report Insights
- Aplastic Anemia Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
Aplastic Anemia Report Assessment
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Key Questions
Current Scenario and Emerging Therapies:
- How many companies are developing Aplastic Anemia drugs?
- How many Aplastic Anemia drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for Aplastic Anemia?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Aplastic Anemia therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Aplastic Anemia and their status?
- What are the key designations that have been granted to the emerging drugs?
Introduction
Executive Summary
Aplastic Anemia: Overview
- Structure
- Mechanism of Action
Pipeline Therapeutics
- Comparative Analysis
Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
Aplastic Anemia– DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
- Aplastic Anemia companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Aplastic Anemia Collaboration Deals
- Company-Company Collaborations (Licensing / Partnering) Analysis
- Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
- Comparative Analysis
PF-06462700: Pfizer
- Product Description
- Research and Development
- Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
- Comparative Analysis
BL-8040: BioLineRx, Ltd.
- Product Description
- Research and Development
- Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
- Comparative Analysis
REGN7257: Regeneron Pharmaceuticals
- Product Description
- Research and Development
- Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
- Comparative Analysis
Aplastic Anemia Key Companies
Aplastic Anemia Key Products
Aplastic Anemia- Unmet Needs
Aplastic Anemia- Market Drivers and Barriers
Aplastic Anemia- Future Perspectives and Conclusion
Aplastic Anemia Analyst Views
Aplastic Anemia Key Companies
Appendix
List of Table
Table 1: Total Products for Aplastic Anemia
Table 2: Late Stage Products
Table 3: Mid Stage Products
Table 4: Early Stage Products
Table 5: Pre-clinical & Discovery Stage Products
Table 6: Assessment by Product Type
Table 7: Assessment by Stage and Product Type
Table 8: Assessment by Route of Administration
Table 9: Assessment by Stage and Route of Administration
Table 10: Assessment by Molecule Type
Table 11: Assessment by Stage and Molecule Type
Table 12: Inactive Products
List of Figures
Figure 1: Total Products for Aplastic Anemia
Figure 2: Late Stage Products
Figure 3: Mid Stage Products
Figure 4: Early Stage Products
Figure 5: Preclinical and Discovery Stage Products
Figure 6: Assessment by Product Type
Figure 7: Assessment by Stage and Product Type
Figure 8: Assessment by Route of Administration
Figure 9: Assessment by Stage and Route of Administration
Figure 10: Assessment by Molecule Type
Figure 11: Assessment by Stage and Molecule Type
Figure 12: Inactive Products
• Pfizer
• BioLineRx, Ltd.
• Regeneron Pharmaceuticals
• Gamida Cell
• Elixirgen
• Hangzhou Zede Pharmaceutical Technology
• Cellenkos
• Hemogenyx Pharmaceuticals