Chronic Rhinosinusitis without Nasal Polyps Epidemiology

Key Highlights

• Chronic Rhinosinusitis without Nasal Polyps prevalence is expected to rise, driven by the increasing prevalence of CRS and a growing awareness of the disease.
• DelveInsight’s analysis indicates that approximately 81% of the total diagnosed cases of CRS in the 7MM were diagnosed as CRSsNP in 2022. Contributing to a large subset of CRS, CRSsNP diagnosis and pathophysiology is still limiting, hereby increasing the disease burden.
• The 7MM gender assessments show that females are predominantly affected by CRSsNP.
• According to DelveInsight’s estimates, the US alone accounted for 52% of the total diagnosed prevalent cases of CRS in the 7MM in 2022.

DelveInsight’s “Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) – Epidemiology – 2034” report delivers an in-depth understanding of Chronic Rhinosinusitis without Nasal Polyps, historical and forecasted epidemiology of Chronic Rhinosinusitis without Nasal Polyps in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

Geography Covered

• The United States
• EU4 (Germany, France, Italy, and Spain) and the United Kingdom
• Japan

Study Period: 2021-2034

Chronic Rhinosinusitis Without Nasal Polyps Disease Understanding

Chronic Rhinosinusitis Without Nasal Polyps Overview

Rhinosinusitis is a broad umbrella term covering multiple disease entities, including acute RS (ARS), CRS with nasal polyps (CRSwNP), and CRS without Nasal Polyps (CRSsNP). Chronic Rhinosinusitis (CRS) is a common complex inflammatory disease defined as persistent sinonasal symptoms lasting at least 12 weeks. Chronic rhinosinusitis without nasal polyps (CRSsNP) is characterized by long-lasting nasal and sinus passages inflammation. Unlike in chronic rhinosinusitis with nasal polyps (CRSwNP), patients with CRSsNP do not have any visible nasal polyps in their nasal cavities or sinuses. CRSsNP can cause persistent symptoms such as nasal congestion, facial pain or pressure, reduced sense of smell, and nasal discharge. These symptoms can significantly impact a person’s quality of life, leading to fatigue, difficulty sleeping, and impaired daily functioning.

Chronic Rhinosinusitis Without Nasal Polyps Diagnosis

CRS can be diagnosed based on more than two of the following four symptoms for at least 12 weeks: anterior/posterior rhinorrhea, nasal congestion, facial pain or pressure, and olfactory dysfunction. Depending on the presence or absence of nasal polyps (NPs), CRS can be classified as CRS with NPs (CRSwNP) or CRS without NPs (CRSsNP). Diagnosing CRSsNP involves thoroughly evaluating the patient’s medical history, physical examination, and, in some cases, imaging studies. Nasal endoscopy may be performed to examine the nasal passages and rule out the presence of polyps. Additionally, imaging tests like computed tomography (CT) scans can provide detailed images of the sinuses.

Further details related to diagnosis are provided in the report…

Chronic Rhinosinusitis Without Nasal Polyps Epidemiology

The Chronic Rhinosinusitis without Nasal Polyps epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by Total Prevalent Cases of Chronic Rhinosinusitis, Total Diagnosed Prevalent Cases of Chronic Rhinosinusitis, Total Diagnosed Prevalent Cases of Chronic Rhinosinusitis Without Nasal Polyps, Gender-specific Cases of Chronic Rhinosinusitis Without Nasal Polyps in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain), United Kingdom, and Japan from 2021 to 2034. The total diagnosed prevalent cases of CRSsNP in the 7MM comprised approximately 17 million cases in 2022 and are projected to increase during the forecast period.

• In 2022, the total prevalent cases of CRS estimated in the 7MM was 71 million, which is further anticipated to rise at a substantial compound annual growth rate (CAGR).
• Out of all total prevalent cases of CRS in the 7MM, 21 million cases were diagnosed in 2022.
• According to our analysis, the United States recorded the highest number of diagnosed CRSsNP cases in 2022, with nearly 8.8 million cases, surpassing other countries in the 7MM. Following the US, estimates suggest higher cases in EU4 and the United Kingdom, with nearly 7 million cases.
• As per DelveInsight’s estimations, Germany had the highest number of diagnosed prevalent cases of CRSsNP (nearly 2.2 million) in 2022, followed by the UK with nearly 1.4 million cases.
• In 2022, nearly 1.1 million cases of CRSsNP were estimated to have received a diagnosis in Japan.
• DelveInsight’s analysis shows that females are predominantly affected by CRSsNP. In 2022, of every 100 males affected, nearly 133 females were estimated to be affected by CRSsNP in the 7MM.

KOL Views

To gaze into the epidemiology insights of the real world, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate our secondary research on disease prevalence.

DelveInsight’s analysts connected with 20+ KOLs to gather insights; however, interviews were conducted with 10+ KOLs in the 7MM. Centers such as the Pneumology and Allergy Department, Hospital Clinic de Barcelona, Barcelona, Catalonia, Department of Otorhinolaryngology, Toho University Ohashi Medical Center, Tokyo, etc., were contacted. Their opinion helps understand and validate current disease prevalence, gender involved with the disease, diagnosis rate, and diagnostic criteria.

Scope of the Report

• The report covers a segment of key events, an executive summary, and a descriptive overview of Chronic Rhinosinusitis without Nasal Polyps, explaining its causes, signs and symptoms, pathogenesis, and diagnosis.
• Comprehensive insight into the epidemiology segments and forecasts, disease progression, and diagnostic criteria has been provided.
• The report provides an edge for understanding trends, expert insights/KOL views, and patient journeys in the 7MM.
• A detailed review of current challenges in establishing the diagnosis.

Chronic Rhinosinusitis Without Nasal Polyps Report Insights

• Patient Population
• Country-wise Epidemiology Distribution
• Total Prevalent Cases of Chronic Rhinosinusitis (CRS)
• Total Diagnosed Prevalent Cases of Chronic Rhinosinusitis (CRS)
• Total Diagnosed Prevalent Cases of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
• Gender-specific Cases of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Chronic Rhinosinusitis Without Nasal Polyps Report Key Strengths

• Ten Years Forecast
• The 7MM Coverage
• Chronic Rhinosinusitis Without Nasal Polyps Epidemiology Segmentation

Chronic Rhinosinusitis Without Nasal Polyps Report Assessment

• Current Diagnostic Practices Patient Segmentation

Epidemiology Insights

• What are the disease risk and burdens of Chronic Rhinosinusitis without Nasal Polyps?
• What is the historical and forecasted Chronic Rhinosinusitis without Nasal Polyps patient pool in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan?
• Why are the diagnosed prevalence rates in Japan lower than in European countries?
• Which gender has a high patient share for Chronic Rhinosinusitis without Nasal Polyps?

Reasons to Buy

• Insights on patient burden/disease, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• To understand the gender-specific Chronic Rhinosinusitis without Nasal Polyps prevalence cases in varying geographies over the coming years.
• A detailed overview of diagnosed prevalent and age-specific cases of Chronic Rhinosinusitis without Nasal Polyps is an inclusion.
• To understand the perspective of key opinion leaders around the current challenges with establishing the diagnosis options.
• Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.

Frequently Asked Questions

1. What are the different types of Chronic Rhinosinusitis (CRS)?

CRS has been divided into two subtypes based on the presence of nasal polyps: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP).

2. Which type of CRS is more common?

CRS without nasal polyps (CRSsNP) is more common than CRS with nasal polyps (CRSwNP), contributing to approximately 81% of cases of CRS.

3. How is epidemiological data collected and analyzed for forecasting purposes?

Epidemiological data is collected through surveys, clinical studies, health records, and other sources. It is then analyzed to calculate disease rates, identify trends, and project future disease burdens using mathematical models.

4. Out of all 7MM countries, which country had the highest prevalent population of Chronic Rhinosinusitis without Nasal Polyps (CRSsNP) in 2022?

The highest cases of CRSsNP were diagnosed in the US among the 7MM in 2022.