dementia related psychosis epidemiology forecast

Dementia-related Psychosis (DRP) Insights and Trends

• Dementia extends far beyond memory loss — it is a complex clinical syndrome in which the majority of patients experience Behavioral and Psychological Symptoms (BPSD), with Dementia-Related Psychosis (DRP).
• DRP is a common and complex neuropsychiatric manifestation characterized by hallucinations, delusions, and impaired reality perception, arising from progressive neurodegeneration and disruption of key neural circuits involved in cognition, perception, and behavioral regulation.
• An estimated 2 million DRP cases were reported in the US in 2025, highlighting the substantial disease burden.
• In EU4 and the UK, Alzheimer's disease dementia accounted for the highest share of type-specific cases, with nearly 4 million cases recorded in 2025, highlighting the substantial and ongoing epidemiological burden across these regions.
• In Japan, apathy dominated the symptom-specific diagnosed prevalent cases of dementia in 2025, with approximately 1.2 million cases, followed by others (~1.1 million), delusion (~885,000), and hallucination (~577,000) — with all categories projected to rise further by 2036, reflecting growing disease recognition and an aging population.
• Diagnosis is primarily clinical and relies on structured assessment tools such as the Neuropsychiatric Inventory (NPI) and Brief Psychiatric Rating Scale (BPRS), along with caregiver-reported observations to evaluate the presence, frequency, and severity of hallucinations and delusions and their impact on daily functioning.
• The rising prevalence of dementia and DRP across major markets highlights a growing public health burden, with aging populations and improved disease recognition expected to drive a continued increase in diagnosed cases over the coming decade.

DelveInsight's ‘Dementia-related Psychosis – Epidemiology Forecast – 2036’ report delivers an in-depth understanding of DRP, historical and forecasted epidemiology in the United States, EU4 (Germany, Spain, Italy, and France), the United Kingdom, and Japan.

Geography Covered

• North America: The United States
• Europe: Germany, France, Italy, Spain and the United Kingdom
• Asia-Pacific: Japan

Dementia-related psychosis Understanding

Dementia-related psychosis: Overview and Diagnosis

DRP is a common and complex neuropsychiatric manifestation characterized by hallucinations, delusions, and impaired reality perception, arising from progressive neurodegeneration and disruption of key neural circuits involved in cognition, perception, and behavioral regulation.

Identifying hallucinations and delusions in DRP is often challenging because busy clinicians may have limited time to take thorough psychiatric histories. To address this, a panel of experts developed the DRP3, a three-question screening tool designed to identify the presence of psychotic symptoms rather than to provide a definitive diagnosis. The diagnosis must specify the underlying Neurocognitive Disorder (NCD), such as Alzheimer’s disease, DLB, vascular dementia, or PDD.

Further details are provided in the report.

Dementia-related psychosis Epidemiology

Key Findings from Dementia-related psychosis Epidemiological Analysis and Forecast

• The US accounted for the largest share of DRP cases within the 7MM, contributing approximately 47% of the overall disease burden, reflecting higher diagnosed prevalence, greater clinical recognition of psychotic symptoms, and more comprehensive reporting practices compared to other regions.
• In 2025, the diagnosed prevalent cases of dementia in the US were distributed by type, with Alzheimer’s disease dementia accounting for more than 5 million cases, followed by others with more than 1 million cases, and DLB with nearly 590,000 cases.
• Among EU4 and the UK, Germany accounted for the highest share of total diagnosed prevalent cases of dementia, contributing approximately 32% of the total cases, followed by France with 22%. In 2025, the total diagnosed prevalent cases of dementia in EU4 and the UK were more than 5 million.
• In 2025, apathy accounted for the largest share of symptoms-specific diagnosed prevalent dementia cases in Japan, with more than 1 million cases, followed by others, delusions, and hallucinations. Cases across all symptom categories are expected to increase by 2036, reflecting a rising burden and improved recognition.

Industry Experts and Physician Views for Dementia-related psychosis

To keep up with DRP dynamic epidemiology trends, we take Key Opinion Leaders (KOLs) and Subject Matter Experts (SMEs) opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry Experts were contacted for insights on the DRP epidemiology, including MD, PhD, Instructor, Postdoctoral Researcher, Professor, Researcher, and others.

DelveInsight’s analysts connected with 10+ KOLs to gather insights at the country level. Centers such as the University of Santo Tomas, Berlin Institute of Health at Charité, Paris-Est Créteil University, UCL Queen Square Institute of Neurology, etc., were contacted.

Their opinion helps understand, validate, highlight, and provide epidemiological context in DRP.

Scope of the Report

• The report covers a segment of an executive summary, a descriptive overview of DRP, explaining their causes, signs, symptoms, and pathogenesis.
• Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of the diagnosis rate, and disease progression along diagnostic guidelines.
• The report provides an edge for understanding trends, expert insights/KOL views, and patient journeys in the 7MM.

A detailed review of current challenges in establishing the diagnosis.

Report Insights

• DRP Patient Population Forecast
• Country-wise Epidemiology Distribution
• Total Diagnosed Prevalent Cases of Dementia
• Type-specific Diagnosed Prevalent Cases of Dementia
• Type-specific Diagnosed Prevalent Cases of Dementia-related Psychosis
• Total Diagnosed Prevalent Cases of Dementia-related Psychosis
• Symptoms-specific Diagnosed Prevalent Cases in Dementia

Report Key Strengths

• Epidemiology-based (Epi-based) Bottom-up Forecasting
• 11-year forecast
• Patient Burden Trends (by geography)
• The 7MM Coverage

FAQs

Epidemiology Insights

• What is the forecast period covered in the report?
• How is epidemiological data collected and analyzed for forecasting purposes?
• Out of all EU4 countries and the UK, which country had the highest population of DRP cases?
• What are the disease risks and burdens of DRP?
• At what compound annual growth rate is the population expected to grow across the 7MM during the forecast period?
• What would be the forecasted patient population of DRP at the 7MM level?

Reasons to Buy

• The report will help in developing business strategies by understanding the latest epidemiology trends.
• Insights on patient burden/ prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• To understand KOLs’ perspectives on the dynamic epidemiology trends.
• This Artificial Intelligence (AI)   enabled report summarize and simplify complex datasets with in the report into clear, actionable insights for stakeholders, investors, and healthcare providers, enabling faster, data driven decisions.