Diabetic Nephropathy Epidemiology

Key Highlights

• DelveInsight’s analyst projects that among the total prevalent cases of Diabetic Nephropathy in 7MM approximately 49% of cases were from the US. As per our estimations, in 2022, the EU4 and the UK accounted for nearly 10 million prevalent cases of Diabetic Nephropathy.
• According to the analysis conducted by DelveInsight, Diabetic Nephropathy was diagnosed in approximately 42% of females and 58% of males within the 7MM in 2022. This analysis indicates a higher prevalence of Diabetic Nephropathy among males than females.
• The highest proportion of Diabetic Nephropathy cases was estimated in the 18-64 years age group in the 7MM, with nearly 63% cases, while age group of 65 years and above had 37% cases.

DelveInsight’s “Diabetic Nephropathy Epidemiology – 2034” report delivers an in-depth understanding of the Diabetic Nephropathy, historical and forecasted epidemiology in the United States, EU4 (Germany, France, Italy, and Spain), and the United Kingdom, and Japan.

Geography Covered

• The United States
• EU4 (Germany, France, Italy, and Spain) and the United Kingdom
• Japan

Study Period: 2021-2034

Disease Understanding and Diagnostic Algorithm

Diabetic Nephropathy Overview

Diabetic nephropathy, also known as diabetic kidney disease (DKD), is a clinical syndrome characterized by persistent albuminuria and a progressive decline in renal function. Diabetic nephropathy is classified into five stages: Stage 1, Stage 2, Stage 3, Stage 4, and Stage 5. These five stages are described as follows: Stage 1 or normoalbuminuria stage, showing normal kidney function or increased estimated glomerular filtration rate (eGFR), of more than 30 mL/min; Stage 2 or microalbuminuric stage, showing microalbuminuria with 30–299 mg/g Cr of urinary albumin excretion (UAE) and Egfr of 30 mL/min; Stage 3 or macroalbuminuric stage, showing macroalbuminuria >300 mg/g Cr of UAE and eGFR of >30 ml/min; Stage 4 or renal failure stage, showing a decline in renal function with eGFR <30 ml/min; and Stage 5 or kidney failure, which is the dialysis stage. Symptoms of diabetic nephropathy include high blood pressure that gets harder to control; swelling of feet, ankles, hands, or eyes; foamy urine; confusion or difficulty thinking; shortness of breath; loss of appetite; nausea and vomiting; itching; tiredness and weakness.

Diabetic Nephropathy Diagnosis

The diagnosis of Diabetic Nephropathy is done by routine screening tests like urinary albumin test (to detect a blood protein called albumin in urine); albumin/creatinine ratio (to measure how much albumin compared to creatinine is in a urine sample); glomerular filtration rate (the measure of creatinine in a blood sample may be used to see how quickly the kidneys filter blood). Other diagnostic tests include: imaging tests (X-rays, ultrasound, CT and MRI scans), kidney biopsy.

Get More Insights of the Report @ Diabetic Nephropathy Treatment Market

Diabetic Nephropathy Epidemiology

As the market is derived using the patient-based model, the Diabetic Nephropathy epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by Prevalence of Diabetic Nephropathy, Gender-specific Cases of Diabetic Nephropathy, Age-specific Cases of Diabetic Nephropathy, and Stage-specific Cases of Diabetic Nephropathy in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain) and the United Kingdom, and Japan, from 2021 to 2034. As per DelveInsight’s estimations, the total prevalent cases of Diabetic Nephropathy in the 7MM were approximately 28 million cases in 2022 and are projected to increase during the forecast period.

• The overall count of individuals prevalent to Diabetic Nephropathy in the United States was approximately 13.7 million in 2022, and it is expected to increase at an estimated CAGR throughout the study period (2021-2034).
• Among the 7MM, EU4 and the UK accounted for nearly 6 million prevalent cases of Diabetic Nephropathy in males and around 4 million cases in females, and these cases are expected to increase during the forecast period (2023-2034).
• The stage-specific cases diabetic nephropathy were classified into stage 1 (eGFR≥90 and UACR≥30 mg/g), stage 2 (eGFR 60–89 and UACR≥30 mg/g), stage 3a (eGFR 45–59), stage 3b (eGFR 30–44), stage 4 (eGFR 15–29) and stage 5 (eGFR <15). Among EU4 and the UK, the United Kingdom had highest prevalent population of Diabetic Nephropathy, in stage 3a with nearly 507 thousand cases, and lowest in stage 5 with around 12 thousand cases, in 2022. 
• In Japan, there were around 2.6 million age-specific cases of Diabetic Nephropathy in the age group of 18-64 years, and 1.5 million cases in age group of 65 years and above, in 2022. These cases are expected to increase at a significant CAGR.

KOL Views

To gaze into the epidemiology insights of the real world, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate the secondary research. Industry Experts were contacted for insights on Diabetic Nephropathy evolving Diabetic Nephropathy Treatment landscape, patient reliance on conventional therapies, patient therapy switching acceptability, along with challenges related to accessibility, including KOL from Icahn School of Medicine at Mount Sinai, School of Medicine, Harvard Medical School, La Sapienza University, Italy, and others.

Delveinsight’s analysts connected with 50+ KOLs to gather insights; however, interviews were conducted with 15+ KOLs in the 7MM. Their opinion helps understand and validate current disease prevalence, gender involved with the disease, diagnosis rate, and diagnostic criteria.

Scope of the Report

• The report covers a segment of key events, an executive summary, descriptive overview of Diabetic Nephropathy, explaining its causes, signs and symptoms, and pathogenesis.
• Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, disease progression, and treatment guidelines.
• The report provides an edge for understanding trends, expert insights/KOL views, and patient journeys in the 7MM.
• A detailed review of current challenges in establishing the diagnosis.

Diabetic Nephropathy Report Insights

• Patient Population
• Country-wise Epidemiology Distribution
• Prevalence of Diabetic Nephropathy
• Gender-specific Cases of Diabetic Nephropathy
• Age-specific Cases of Diabetic Nephropathy
• Stage-specific Cases of Diabetic Nephropathy 

Diabetic Nephropathy Report Key Strengths

• 12 years Forecast
• The 7MM Coverage 
• Diabetic Nephropathy Epidemiology Segmentation

Key Questions

Epidemiology Insights

• What are the disease risks, burdens, and unmet needs of Diabetic Nephropathy? What will be the growth opportunities across the 7MM concerning the patient population of Diabetic Nephropathy?
• What is the historical and forecasted Diabetic Nephropathy patient pool in the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan?
• Why do only limited patients appear for diagnosis? 
• Which country is more prevalent for Diabetic Nephropathy and why?
• What factors are affecting the diagnosis of the indication? 

Reasons to Buy

• Insights on patient burden/disease, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• To understand the Diabetic Nephropathy prevalence cases in varying geographies over the coming years.
• A detailed overview of Stage, Gender, and Age-specific prevalence of Diabetic Nephropathy.
• To understand the perspective of key opinion leaders around the current challenges with establishing the diagnosis options.
• Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.

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Frequently Asked Questions

1. What is the forecast period covered in the report?

The Diabetic Nephropathy Epidemiology report for the 7MM covers the forecast period from 2023 to 2034, providing a projection of epidemiology dynamics and trends during this timeframe.

2. Out of all EU4 countries and the UK, which country had the highest population of Diabetic Nephropathy cases in 2022?

The highest cases of Diabetic Nephropathy was found in the Germany, among EU4 and the UK, in 2022.

3. How is epidemiological data collected and analyzed for forecasting purposes?

Epidemiological data is collected through surveys, clinical studies, health records, and other sources. It is then analyzed to calculate disease rates, identify trends, and project future disease burdens using mathematical models.

4. Out of all 7MM countries, which country had the highest population of Diabetic Nephropathy cases in 2022?

The highest cases of Diabetic Nephropathy were found in the US, among the 7MM, in 2022.