Glioblastoma Market Research Report present a detailed analysis of the market listing Glioblastoma Epidemiology, Drug therapies and pipeline for study period from 2016-2018.

Glioblastoma Market Size & Share | Glioblastoma Market Research Report, Market Analysis, Market Growth, trends and Forecast

DelveInsight's 'Glioblastoma - Market Insights, Epidemiology and Market Forecast-2028' report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the market trends of Glioblastoma in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan. The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Glioblastoma from 2017 to 2028 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market. Geography Covered • The United States • EU5 (Germany, France, Italy, Spain and the United Kingdom) • Japan <h2>Study Period: 2017-2028</h2><h2>Glioblastoma - Disease Understanding and Treatment Algorithm</h2> Glioblastoma (GBM) is the most frequently occurring type of primary tumors of the central nervous system (CNS) mostly in adults, and its poor prognosis has not been significantly improved despite the fact that the innovative diagnostic strategies and new therapies have been developed. Somatic evolution promotes the progression of cancer in which the genome of the cancer cell is being deviated from that of the healthy cell due the accumulation of mutations. There is a remarkable development in GBM because it occurs via a complex network of various different molecular and genetic aberrations, which leads to significant changes in major signaling pathways. GBMs, as they extensively disperse throughout the parenchyma, making maximal surgical resection unattainable and having high level of vascularization, are lethal in nature.GBM is often located in a region of the forebrain known as the cerebrum, which controls some of the most advanced process such as speech and emotions. While GBM is highly locally invasive (invading normal brain tissue), it rarely spreads to other organs beyond the brain. A highly aggressive, fast-growing cancer and treatment is often limited by the tumor location and the ability of a patient to tolerate surgery. Consequently, it is a particularly difficult cancer to treat.The DelveInsight Glioblastoma market report gives the thorough understanding of the Glioblastoma by including details such as disease definition, classification, types, symptoms, pathophysiology, inheritance, molecular classification diagnostic trends. It also provides treatment algorithms and treatment guidelines for Glioblastoma in the US, Europe, and Japan. <h2>Glioblastoma Epidemiology</h2>The Glioblastoma epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken. The disease epidemiology covered in the report provides historical as well as forecasted epidemiology [segmented by Total Incident Population of Glioblastoma, Total Diagnosed Incident Population of Glioblastoma, Gender specific Diagnosed Incidence of Glioblastoma, Type specific Diagnosed Incidence of Glioblastoma and Incident Population of Associated Comorbidities in Glioblastoma scenario of Glioblastoma in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2017-2028.According to DelveInsight, incident population of Glioblastoma associated with menopause in 7MM countries is expected to increase at a CAGR of 1.11% for the study period i.e. 2017-2028. As per the estimates, United States has the highest incident population of Glioblastoma. Among the European countries, UK had the highest incident population of Glioblastoma with 3,492 cases, followed by France which had incident population of 2,683 in 2017. <h2>Glioblastoma Drug Chapters</h2>This segment of the Glioblastoma report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.The current therapeutic landscape of Glioblastoma in the report provides the detailed chapters of upcoming therapies such as late-stage therapies including Marizomib (Celgene), VAL-083 (DelMar Pharmaceuticals), JP0001 (Johnpro Biotech), and many more with the mid-stage products like Enzastaurin Hydrochloride (Denovo Biopharma; Eli Lilly), ALECSAT (CytoVac) and others, which are expected to launch during the forecast period [2019-2028] have also been covered in the report. <h2>Glioblastoma Market Outlook</h2>The Glioblastoma market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology. This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight. According to DelveInsight, the market size of Glioblastoma in the seven major markets is expected to reach around USD 2,306 million by 2028. The United States accounts for the highest market size of Glioblastoma in comparison to the EU5 (the United Kingdom, Germany, Italy, France, and Spain), and Japan. Expected Launch of potential therapies may increase market size in the coming years, assisted by an increase in diagnosed incident population of Glioblastoma Multiforme. Owing to the positive outcomes of the several products during the developmental stage by key players such as DelMar Pharmaceuticals, Abbvie, Diffusion Pharmaceuticals, Tocagen, Apogenix etc. has a potential to create a significant positive shift in the Glioblastoma market size. DelveInsight's analysts estimate that the market is expected to show positive growth post 2022, due to the increased patient incidence and to the expected launch of emerging therapies. <h2>Glioblastoma Drugs Uptake</h2>This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2017-2028. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug. This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.Expected launch of therapies for Glioblastoma such as Celgene's Marizomib, DelMar's VAL-083, Green Cross Cell's Immuncell-LC and other targeted therapies in the forecast period [2019-2028] will also create a positive impact on the Glioblastoma market. <h2>Glioblastoma Report Insights</h2> • Patient Population • Therapeutic Approaches • Pipeline Analysis • Market Size and Trends • Market Opportunities • Impact of upcoming Therapies <h2>Glioblastoma Report Key Strengths</h2> • 10 Years Forecast • 7MM Coverage • Epidemiology Segmentation • Key Cross Competition • Market Size by Therapies • Drugs Uptake <h2>Glioblastoma Report Assessment</h2> • Pipeline Product Profiles • Key Products and Key Players • Market Drivers and Barriers <h2>Key Benefits</h2> • This DelveInsight report will help to develop Business Strategies by understanding the trends shaping and driving Glioblastoma market • Organize sales and marketing efforts by identifying the best opportunities for Glioblastoma market • To understand the future market competition in the Glioblastoma market.

1 KEY INSIGHTS 2 GLIOBLASTOMA MULTIFORME MARKET OVERVIEW AT A GLANCE 2.1 MARKET SHARE (%) DISTRIBUTION OF GLIOBLASTOMA MULTIFORME IN 2017 2.2 MARKET SHARE (%) DISTRIBUTION OF GLIOBLASTOMA MULTIFORME IN 2028 3 DISEASE BACKGROUND AND OVERVIEW: GLIOBLASTOMA MULTIFORME (GBM) 3.1 INTRODUCTION 3.2 CLASSIFICATION OF GLIOBLASTOMA MULTIFORME 3.3 GLIOBLASTOMA TYPES 3.3.1 Astrocytomas 3.3.2 Ependymomas 3.3.3 Oligodendrogliomas 3.3.4 Mixed gliomas 3.3.5 Optic pathway gliomas 3.4 SYMPTOMS 3.5 PATHOPHYSIOLOGY 3.5.1 Macroscopic and Histological Features of GBM 3.5.2 Genetic and Molecular Pathogenesis 3.6 INHERITANCE OF GLIOBLASTOMA MULTIFORME 3.6.1 Genetic Variations of Glioblastoma Multiforme 3.7 MOLECULAR CLASSIFICATION 3.7.1 Specific Molecular Biomarkers 3.8 DIAGNOSIS OF GLIOBLASTOMA MULTIFORME 3.8.1 Neurological Exams 3.8.2 Angiograms 3.8.3 Magnetic resonance imaging (MRI) and computerized Tomography (CT) 3.8.4 Perfusion MRI 3.8.5 MR spectroscopy 3.8.6 Histological Diagnosis 3.8.7 Surgical Biopsy 3.9 GLIOBLASTOMA IN NUT SHELL 4 EPIDEMIOLOGY AND PATIENT POPULATION 4.1 KEY FINDINGS 4.2 7MM TOTAL PATIENT POPULATION OF GLIOBLASTOMA MULTIFORME 4.1 7MM TOTAL DIAGNOSED PATIENT POPULATION OF GLIOBLASTOMA MULTIFORME 5 COUNTRY WISE-EPIDEMIOLOGY OF GLIOBLASTOMA MULTIFORME 5.1 UNITED STATES 5.1.1 Assumptions and Rationale 5.1.2 Total Incident Population of Glioblastoma Multiforme in the United States 5.1.3 Total Diagnosed Incident Population of Glioblastoma Multiforme in the United States 5.1.4 Gender specific Diagnosed Incidence of Glioblastoma Multiforme in the United States 5.1.5 Type specific Diagnosed Incidence of Glioblastoma Multiforme in the United States 5.1.6 Incident Population of Associated Comorbidities in Glioblastoma Multiforme in the United States 5.2 EU5 COUNTRIES 5.2.1 Assumptions and Rationale 5.3 GERMANY 5.3.1 Total Incident Population of Glioblastoma Multiforme in Germany 5.3.2 Total Diagnosed Incident Population of Glioblastoma Multiforme in Germany 5.3.3 Gender specific Diagnosed Incidence of Glioblastoma Multiforme in Germany 5.3.4 Type specific Diagnosed Incidence of Glioblastoma Multiforme in Germany 5.3.5 Incident Population of Associated Comorbidities in Glioblastoma Multiforme in Germany 5.4 FRANCE 5.4.1 Total Incident Population of Glioblastoma Multiforme in France 5.4.2 Total Diagnosed Incident Population of Glioblastoma Multiforme in France 5.4.3 Gender specific Diagnosed Incidence of Glioblastoma Multiforme in the United States 5.4.4 Type specific Diagnosed Incidence of Glioblastoma Multiforme in France 5.4.5 Incident Population of Associated Comorbidities in Glioblastoma Multiforme in France 5.5 ITALY 5.5.1 Total Incident Population of Glioblastoma Multiforme in Italy 5.5.2 Total Diagnosed Incident Population of Glioblastoma Multiforme in Italy 5.5.3 Gender specific Diagnosed Incidence of Glioblastoma Multiforme in Italy 5.5.4 Type specific Diagnosed Incidence of Glioblastoma Multiforme in Italy 5.5.5 Incident Population of Associated Comorbidities in Glioblastoma Multiforme in Italy 5.6 SPAIN 5.6.1 Total Incident Population of Glioblastoma Multiforme in Spain 5.6.2 Total Diagnosed Incident Population of Glioblastoma Multiforme in Spain 5.6.3 Gender specific Diagnosed Incidence of Glioblastoma Multiforme in Spain 5.6.4 Type specific Diagnosed Incidence of Glioblastoma Multiforme in Spain 5.6.5 Incident Population of Associated Comorbidities in Glioblastoma Multiforme in Spain 5.7 UNITED KINGDOM 5.7.1 Total Incident Population of Glioblastoma Multiforme in the United Kingdom 5.7.2 Total Diagnosed Incident Population of Glioblastoma Multiforme in the United Kingdom 5.7.3 Gender specific Diagnosed Incidence of Glioblastoma Multiforme in the United Kingdom 5.7.4 Type specific Diagnosed Incidence of Glioblastoma Multiforme in the United Kingdom 5.7.5 Incident Population of Associated Comorbidities in Glioblastoma Multiforme in the United Kingdom 5.8 JAPAN 5.8.1 Assumptions and Rationale 5.8.2 Total Incident Population of Glioblastoma Multiforme in Japan 5.8.3 Total Diagnosed Incident Population of Glioblastoma Multiforme in Japan 5.8.4 Gender specific Diagnosed Incidence of Glioblastoma Multiforme in Japan 5.8.5 Type specific Diagnosed Incidence of Glioblastoma Multiforme in Japan 5.8.6 Incident Population of Associated Comorbidities in Glioblastoma Multiforme in Japan 6 TREATMENT 6.1 SURGERY 6.2 CHEMOTHERAPY 6.3 RADIATION 6.4 OTHERS 6.4.1 Targeted therapy 6.4.2 Tumor treatment fields (TTF) 6.4.3 Immunotherapy 6.5 MANAGEMENT OF SYMPTOMS WITH MEDICATION 7&nbsp;TREATMENT ALGORITHM 8 UNMET NEEDS 9 MARKETED DRUGS 9.1 AVASTIN: GENENTECH 9.1.1 Drug Description 9.1.2 Regulatory Milestones 9.1.3 Other Development Activities 9.1.4 Safety and Efficacy 9.1.5 Product Profile 9.2 TEMODAR/TEMODAL: MERCK 9.2.1 Drug Description 9.2.2 Regulatory Milestones 9.2.3 Other Development Activities 9.2.4 Safety and Efficacy 9.2.5 Product Profile 10 EMERGING DRUGS 10.1 KEY CROSS COMPETITION (LATE-STAGE EMERGING DRUGS) 10.2 KEY CROSS COMPETITION (MID-STAGE EMERGING DRUGS) 10.3 CAR-T IMMUNOTHERAPY DEVELOPMENT PRODUCTS 10.4 IMMUNCELL-LC: GREEN CROSS CELL CORPORATION 10.4.1 Product Description 10.4.2 Other Development Activities 10.4.3 Clinical Development 10.4.4 Product Profile 10.5 MARIZOMIB: CELGENE 10.5.1 Product Description 10.5.2 Other Development Activities 10.5.3 Clinical Development 10.5.4 Product Profile 10.6 DIANHYDROGALACTITOL (VAL-083): DELMAR PHARMACEUTICALS 10.6.1 Product Description 10.6.2 Other Development Activities 10.6.3 Clinical Development 10.6.4 Product Profile 10.7 OFRANERGENE OBADENOVEC (VB-111): VBL THERAPEUTICS 10.7.1 Product Description 10.7.2 Other Development Activities 10.7.3 Clinical Development 10.7.4 Product Profile 10.8 DEPATUXIZUMAB MAFODOTIN (ABT-414): ABBVIE 10.8.1 Product Description 10.8.2 Other Development Activities 10.8.3 Clinical Development 10.8.4 Safety and Efficacy 10.8.5 Product Profile 10.9 TRANS SODIUM CROCETINATE: DIFFUSION PHARMACEUTICALS 10.9.1 Product Description 10.9.2 Other Development Activities 10.9.3 Clinical Development 10.9.4 Safety and Efficacy 10.9.5 Product Profile 10.10 SIROQUINE (JP001): JOHNPRO BIOTECH 10.10.1 Product Description 10.10.2 Other Development Activities 10.10.3 Clinical Development 10.10.4 Product Profile 10.11 NIVOLUMAB: BRISTOL-MYERS SQUIBB/ONO PHARMACEUTICALS 10.11.1 Product Description 10.11.2 Other Development Activities 10.11.3 Clinical Development 10.11.4 Safety and Efficacy 10.11.5 Product Profile 10.12 IPILIMUMAB: BRISTOL-MYERS SQUIBB 10.12.1 Product Description 10.12.2 Other Development Activities 10.12.3 Clinical Development 10.12.4 Safety and Efficacy 10.12.5 Product Profile 10.13 ASUNERCEPT: APOGENIX 10.13.1 Product Description 10.13.2 Other Development Activities 10.13.3 Clinical Development 10.13.4 Product Profile 10.14 TOCA 511 AND TOCA FC: TOCAGEN 10.14.1 Product Description 10.14.2 Other Development Activities 10.14.3 Clinical Development 10.14.4 Product Profile 10.15 TASADENOTUREV: DNATRIX 10.15.1 Product Description 10.15.2 Other Development Activities 10.15.3 Clinical Development 10.15.4 Product Profile 11 GLIOBLASTOMA MULTIFORME: 7 MAJOR MARKET ANALYSIS 11.1&nbsp;KEY FINDINGS 11.2 MARKET SIZE OF GLIOBLASTOMA MULTIFORME IN 7MM 12 THE UNITED STATES MARKET OUTLOOK 12.1 UNITED STATES MARKET SIZE 12.1.1 Total Market size of Glioblastoma Multiforme 12.1.2 Market Size by Therapies 13 EU-5 COUNTRIES: MARKET OUTLOOK 13.1 GERMANY 13.1.1 Total Market size of Glioblastoma Multiforme in Germany 13.1.2 Market Size by Therapies 13.2 FRANCE 13.2.1 Total Market Size of Glioblastoma Multiforme 13.2.2 Market Size by Therapies 13.3 ITALY 13.3.1 Total Market Size of Glioblastoma Multiforme 13.3.2 Market Size by Therapies 13.4 SPAIN 13.4.1 Total Market Size of Glioblastoma Multiforme 13.4.2 Market Size by Therapies 13.5 UNITED KINGDOM 13.5.1 Total Market Size of Glioblastoma Multiforme 13.5.2 Market Size by Therapies 14 JAPAN: MARKET OUTLOOK 14.1 JAPAN MARKET SIZE 14.1.1 Total Market Size of Glioblastoma Multiforme 14.1.2 Market Size by Therapies 15 MARKET DRIVERS 16 MARKET BARRIERS 17 APPENDIX 17.1 REPORT METHODOLOGY 18 DELVEINSIGHT CAPABILITIES 19 DISCLAIMER 20 ABOUT DELVEINSIGHT

Glioblastoma - Market Insight, Epidemiology and Market Forecast - 2028

DelveInsight's 'Glioblastoma - Market Insights, Epidemiology and Market Forecast-2028' report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Glioblastoma in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan. 