Moderate to Severe Atopic Dermatitis (AD) Epidemiology

Key Highlights

• Atopic dermatitis, also called eczema, is a multifaceted, chronic relapsing inflammatory skin disease commonly associated with other atopic manifestations such as food allergy, allergic rhinitis, and asthma. 
• Among the 7MM, the US accounted for the highest number of cases in 2024, with around 32,941,520 prevalent cases of atopic dermatitis. These cases are expected to increase during the forecast period.
• The severity data from secondary findings confirms that most atopic dermatitis cases are mild to moderate in severity, regardless of age group. 
• As per analysis, atopic dermatitis is associated with a higher disease burden in women than in men.

DelveInsight’s "Moderate-to Severe Atopic Dermatitis – Epidemiology – 2034" report delivers an in-depth understanding of moderate-to severe atopic dermatitis, historical and forecasted epidemiology trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

Geography Covered

• The United States
• EU4 (Germany, France, Italy, and Spain) and the United Kingdom
• Japan

Study Period: 2021-2034

Moderate-to Severe Atopic Dermatitis Disease Understanding

Moderate-to Severe Atopic Dermatitis Overview

Moderate-to-severe atopic dermatitis is a chronic inflammatory skin condition characterized by intense itching, red and inflamed lesions, and significant dryness, often leading to lichenification from chronic scratching. It primarily affects children but can persist into adulthood, impacting the quality of life through sleep disturbances and social withdrawal. The condition is associated with genetic predispositions, immune dysregulation, and environmental triggers, and it is part of the "atopic march," which can lead to other allergic diseases like asthma and allergic rhinitis. Patients frequently experience a range of symptoms that can vary in severity, and while some may see improvement over time, many continue to deal with the challenges posed by this persistent condition.

Moderate-to Severe Atopic Dermatitis Diagnosis

Currently, no specific test for atopic dermatitis exists, and no single symptom or feature can be used to identify the disease. Each patient has a unique combination of symptoms and rash appearance. Diagnosis of atopic dermatitis is based on the history and physical examination of the patient. In uncertain cases, a skin biopsy may be taken for a histopathological diagnosis of dermatitis.

Further details related to diagnosis will be provided in the report…

Moderate-to Severe Atopic Dermatitis Epidemiology

The moderate-to severe atopic dermatitis epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by the total prevalent cases of atopic dermatitis, total prevalent cases of atopic dermatitis by age, total diagnosed cases of atopic dermatitis, total diagnosed cases of atopic dermatitis by severity, and total diagnosed cases of atopic dermatitis by gender in the 7MM covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2021 to 2034.

• Atopic dermatitis is a common condition that usually begins in childhood; however, anyone can get the disease at any age. It has been observed that the prevalence of atopic dermatitis is higher in children than adults across 7MM. 
• Among EU4 and the UK, the highest number of cases of atopic dermatitis was found in the UK whereas the Spain accounted for the lowest cases in 2024.
• In 2024, the total atopic dermatitis diagnosed prevalent cases were approximately 53,743,120 in the 7MM.
• The US accounted for approximately 9,993,230 cases of moderate to severe atopic dermatitis in 2024.  
• In the EU4 and the UK, in 2024, the total prevalent cases of atopic dermatitis by age were ~9,206,870 for patients >18 years and ~21,407,420 for patients 18 years and above, which is expected to increase by 2034.
• As per the DelveInsight estimates, it has been found that the highest total diagnosed cases of atopic dermatitis by severity were ~31,022,520 for mild in 7MM in 2024.
• In 2024, total diagnosed cases of atopic dermatitis by gender were ~10,348,580 in females and                 ~6,243,670 in males in the US.

Moderate-to Severe Atopic Dermatitis Report Insights

Moderate-to Severe Atopic Dermatitis Report Insights

• Patient Population
• Country-wise Epidemiology Distribution

Moderate-to Severe Atopic Dermatitis Report Key Strengths

• Ten Years Forecast
• 7MM Coverage 
• Moderate-to Severe Atopic Dermatitis Epidemiology Segmentation

FAQs

• What are the disease risks, burdens, and unmet needs of moderate-to severe atopic dermatitis? What will be the growth opportunities across the 7MM concerning the patient population with moderate-to severe atopic dermatitis?
• What is the historical and forecasted moderate-to severe atopic dermatitis patient pool in the US, EU4 (Germany, France, Italy, and Spain) the UK, and Japan?

Reasons to Buy

• Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.

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