The Ovarian Cancer pipeline report provides detailed information of the Ovarian Cancer pipeline products from the initial phase of product development until its commercialisation in the Ovarian Cancer market.

Ovarian Cancer Pipeline Insight | Ovarian Cancer Pipeline Assessment, Pipeline Drugs

DelveInsight&rsquo;s, &ldquo;Ovarian Cancer - Pipeline Insight, 2025,&rdquo; report provides comprehensive insights about 180+ companies and 200+ pipeline drugs in Ovarian Cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.&nbsp;
<h2>Geography Covered</h2>
<ul>
<li>Global coverage</li>
</ul>
<h2>Ovarian Cancer Understanding</h2>
Ovarian Cancer: Overview
Ovarian cancer is the leading cause of death in women diagnosed with gynecological cancers. It is also the fifth most frequent cause of death in women, in general. Most of the cases are diagnosed at an advanced stage, which leads to poor outcomes of this disease. The existing screening tests have a low predictive value contributing further to this misery. Detailed gynecological evaluation along with transvaginal ultrasound and laboratory marker like cancer antigen-125 (CA-125) assay are the key early detection strategies which have shown no significant beneficial effect in the morbidity or mortality of this cancer.
&nbsp;
The four most common histological types of epithelial ovarian cancer are serous, endometrioid, clear cell, and mucinous tumor.&nbsp; They have further subtypes based on their peculiar biology and treatment responses. The uncommon subtypes are Brenner and seromucinous.
&nbsp;
Ovarian cancer can be further classified into two subtypes- Type I or Type II tumors, the latter being a more fatal variant, thought to be caused by continuous ovarian cycles leading to inflammation and endometriosis. Type I tumor includes low-grade serous, endometrioid, clear-cell, and mucinous carcinomas, with the rare subtypes being seromucinous and Brenner tumors. Type I tumors mostly arise from atypical proliferative (borderline) tumors. Type II tumors include high-grade serous carcinoma, carcinosarcoma, and undifferentiated carcinoma, which mainly originate from serous tubal intraepithelial carcinoma. Type I tumors usually present at an early stage and are low grade except for clear cell, which is considered high grade. Their proliferative activity is usually low. They are diagnosed early and carry a good prognosis. In comparison, Type II tumors are high-grade tumors and almost always of advanced stage. They have high proliferative activity with rapid and aggressive progression and a high degree of chromosomal instability compared to type I with the presence of p53 mutations in most of the cases.
&nbsp;
The standard line of care treatment includes surgery and platinum-based chemotherapy; however, anti-angiogenic bevacizumab and Poly (ADP-ribose) polymerase (PARP) inhibitors have gained momentum in the management of this gynecological malignancy in the past decade. A high rate of recurrence following the initial treatment has been observed. Most of these relapsed cases are less curable and known to have an increased incidence of treatment failures. Hence, effective prevention and detection strategies and new treatment modalities based on a better understanding of molecular characterization of this cancer are the need of the hour.&nbsp;
&nbsp;
"Ovarian Cancer- Pipeline Insight, 2025" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Ovarian Cancer pipeline landscape is provided which includes the disease overview and Ovarian Cancer treatment guidelines. The assessment part of the report embraces, in depth Ovarian Cancer commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Ovarian Cancer collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
<h2>Report Highlights</h2>
The companies and academics are working to assess challenges and seek opportunities that could influence Ovarian Cancer R&amp;D. The therapies under development are focused on novel approaches to treat/improve Ovarian Cancer.
<h2>Ovarian Cancer Emerging Drugs Chapters</h2>
This segment of the Ovarian Cancer report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
&nbsp;
Ovarian Cancer Emerging Drugs
&nbsp;
Atezolizumab: Genentech
Atezolizumab is a humanized kappa immunoglobulin (Ig) G1 monoclonal antibody consisting of two heavy chains (448 amino acids) and two light chains (214 amino acids) and is produced in Chinese hamster ovary cells. Atezolizumab was engineered to eliminate Fc-effector function via a single amino acid substitution (asparagine to alanine) at position 298 on the heavy chain, which results in a non-glycosylated antibody that has minimal binding to Fc receptors and, consequently, eliminates detectable Fc-effector function and depletion of cells expressing programmed death&minus;ligand 1 (PD-L1) in humans. Atezolizumab targets human PD-L1 and inhibits its interaction with its receptors, programmed death&minus;1 (PD-1) and B7.1, both of which can provide inhibitory signals to T cells. The drug is currently in phase 3 of clinical trials for the treatment of Ovarian Cancer.
&nbsp;
Tisotumab Vedotin: Genmab
Tisotumab vedotin, also known as HuMax-TF, HuMax&reg;-TF-ADC or TF-011-MMAE, is an antibody-drug conjugate (ADC) targeted to tissue factor (TF), a protein involved in tumor signaling and angiogenesis. Tisotumab vedotin includes an antibody targeting TF conjugated with monomethyl auristatin E (MMAE) via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. The drug is currently in phase 2 of clinical trials for the treatment of Ovarian Cancer.
&nbsp;
SON-1010: Sonnet Biotherapeutics
SON-1010 is a proprietary version of native human IL-12, configured using Sonnet's fully human albumin binding (FHAB&reg;) platform, which targets the tumor microenvironment (TME) and extends the pharmacokinetics (PK) and subsequent pharmacodynamics (PD) of the molecule. Sonnet and Roche have entered into a Master Clinical Trial and Supply Agreement (MCSA), along with ancillary Quality and Safety Agreements, to study the safety and efficacy of the combination of SON-1010 and atezolizumab in a platinum-resistant ovarian cancer (PROC) patient setting. Currently the drug is in the Phase I/II stage of its development for the treatment of ovarian cancer.
&nbsp;
DS-6000a: Daiichi Sankyo Company
DS-6000a is an antibody-drug conjugate, comprised of an humanized anti-CDH6 IgG1 monoclonal antibody attached to a topoisomerase I (TOP1) inhibitor payload via a cleavable linker. DS-6000a specifically binds to CDH6 on the surface of tumor cells and is internalized upon binding. The payload is then released, resulting in target cell apoptosis. In preclinical studies, DS-6000a inhibited tumor growth and induced tumor regression in CDH6-expressing RCC and OVC. Currently the drug is in Phase I stage of Clinical trial evaluation for the treatment of Ovarian Cancer.
Further product details are provided in the report&hellip;&hellip;..
<h2>Ovarian Cancer: Therapeutic Assessment</h2>
This segment of the report provides insights about the different Ovarian Cancer drugs segregated based on following parameters that define the scope of the report, such as:
&nbsp;
Major&nbsp;Players in Ovarian Cancer
There are approx. 180+ key companies which are developing the therapies for Ovarian Cancer. The companies which have their Ovarian Cancer drug candidates in the most advanced stage, i.e. phase III include, Genentech.
&nbsp;
Phases
DelveInsight&rsquo;s report covers around 200+ products under different phases of clinical development like
<ul>
<li>Late stage products (Phase III)</li>
<li>Mid-stage products (Phase II)</li>
<li>Early-stage product (Phase I) along with the details of</li>
<li>Pre-clinical and Discovery stage candidates</li>
<li>Discontinued &amp; Inactive candidates</li>
</ul>
&nbsp;
Route of Administration
Ovarian Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
<ul>
<li>Oral</li>
<li>Intravenous</li>
<li>Subcutaneous</li>
<li>Parenteral&nbsp;</li>
<li>Topical</li>
</ul>
&nbsp;
Molecule Type
Products have been categorized under various Molecule types such as
<ul>
<li>Recombinant fusion proteins</li>
<li>Small molecule</li>
<li>Monoclonal antibody</li>
<li>Peptide</li>
<li>Polymer&nbsp;</li>
<li>Gene therapy</li>
</ul>
&nbsp;
Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
<h2>Ovarian Cancer: Pipeline Development Activities</h2>
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Ovarian Cancer therapeutic drugs key players involved in developing key drugs.
&nbsp;
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Ovarian Cancer drugs.
&nbsp;
Learn how the therapeutic market will evolve and grow in the coming years:&nbsp;<a href="../../report-store/ovarian-cancer-market">Ovarian Cancer Market</a> &nbsp;
<h2>Ovarian Cancer Report Insights</h2>
<ul>
<li>Ovarian Cancer Pipeline Analysis</li>
<li>Therapeutic Assessment</li>
<li>Unmet Needs</li>
<li>Impact of Drugs</li>
</ul>
<h2>Ovarian Cancer Report Assessment</h2>
<ul>
<li>Pipeline Product Profiles</li>
<li>Therapeutic Assessment</li>
<li>Pipeline Assessment</li>
<li>Inactive drugs assessment</li>
<li>Unmet Needs</li>
</ul>
<h2>Key Questions</h2>
Current Treatment Scenario and Emerging Therapies:
<ul>
<li>How many companies are developing Ovarian Cancer drugs?</li>
<li>How many Ovarian Cancer drugs are developed by each company?</li>
<li>How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Ovarian Cancer?</li>
<li>What are the key collaborations (Industry&ndash;Industry, Industry&ndash;Academia), Mergers and acquisitions, licensing activities related to the Ovarian Cancer therapeutics?</li>
<li>What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?</li>
<li>What are the clinical studies going on for Ovarian Cancer and their status?</li>
<li>What are the key designations that have been granted to the emerging drugs?</li>
</ul>

Introduction
Executive Summary
Ovarian Cancer: Overview
<ul>
<li class="MsoNormal">Introduction</li>
<li class="MsoNormal">Causes</li>
<li class="MsoNormal">Pathophysiology</li>
<li class="MsoNormal">Signs and Symptoms</li>
<li class="MsoNormal">Diagnosis</li>
<li class="MsoNormal">Treatment</li>
</ul>
Pipeline Therapeutics
<ul>
<li class="MsoNormal">Comparative Analysis</li>
</ul>
Therapeutic Assessment
<ul>
<li class="MsoNormal">Assessment by Product Type</li>
<li class="MsoNormal">Assessment by Stage and Product Type</li>
<li class="MsoNormal">Assessment by Route of Administration</li>
<li class="MsoNormal">Assessment by Stage and Route of Administration</li>
<li class="MsoNormal">Assessment by Molecule Type</li>
<li class="MsoNormal">Assessment by Stage and Molecule Type</li>
</ul>
Ovarian Cancer&ndash; DelveInsight&rsquo;s Analytical Perspective
Late Stage Products (Phase III)
<ul>
<li>Comparative Analysis</li>
</ul>
Atezolizumab: Genentech
<ul>
<li class="MsoNormal">Product Description</li>
<li class="MsoNormal">Research and Development</li>
<li class="MsoNormal">Product Development Activities</li>
</ul>
Drug profiles in the detailed report&hellip;..
Mid Stage Products (Phase II)
<ul>
<li>Comparative Analysis</li>
</ul>
Tisotumab Vedotin: Genmab
<ul>
<li class="MsoNormal">Product Description</li>
<li class="MsoNormal">Research and Development</li>
<li class="MsoNormal">Product Development Activities</li>
</ul>
Drug profiles in the detailed report&hellip;..
Early Stage Products (Phase I) 
<ul>
<li>Comparative Analysis</li>
</ul>
DS-6000a: Daiichi Sankyo Company
<ul>
<li class="MsoNormal">Product Description</li>
<li class="MsoNormal">Research and Development</li>
<li class="MsoNormal">Product Development Activities</li>
</ul>
Drug profiles in the detailed report&hellip;..
Preclinical and Discovery Stage Products 
<ul>
<li>Comparative Analysis</li>
</ul>
Product Name: Company Name
<ul>
<li class="MsoNormal">Product Description</li>
<li class="MsoNormal">Research and Development</li>
<li class="MsoNormal">Product Development Activities</li>
</ul>
Drug profiles in the detailed report&hellip;..
Inactive Products
<ul>
<li>Comparative Analysis</li>
</ul>
Ovarian Cancer Key Companies
Ovarian Cancer Key Products
Ovarian Cancer- Unmet Needs
Ovarian Cancer- Market Drivers and Barriers
Ovarian Cancer- Future Perspectives and Conclusion
Ovarian Cancer Analyst Views
Ovarian Cancer Key Companies
 
Appendix

DelveInsight’s, “Ovarian Cancer - Pipeline Insight, 2023,” report provides comprehensive insights about 180+ companies and 200+ pipeline drugs in Ovarian Cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. 

Ovarian Cancer Pipeline

Ovarian Cancer - Pipeline Insight, 2025

"Ovarian Cancer Pipeline Insights, 2025" report by DelveInsight outlays comprehensive insights of present clinical development scenario and growth prospects across the Ovarian Cancer market.