Parainfluenza Virus Infection Market

• The Parainfluenza Virus Infection Market is projected to witness consistent growth throughout the forecast period (2024–2034). The Parainfluenza Virus Infection Market Size in the 7MM is expected to increase, driven by increasing Incident population.
• DelveInsight’s analyst projects that the Parainfluenza Virus Infection Incident Cases in 7MM were approximately 2,709,923 in 2023 and these cases are further expected to increase during the forecasted period (2024–2034).
• Most number of Parainfluenza Virus Infection Incident cases were estimated in the US, followed by Japan, Spain, and Germany in 2023.
• In the 7MM, the Parainfluenza Virus Infection Drugs Market mainly consisted of standard of care, which generated nearly USD 259 million in 2023.
• The total Parainfluenza Virus Infection Treatment Market Size is anticipated to experience growth during the forecast period due to the increase in incident population of PIV Infection.

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Key Factors Driving the Parainfluenza Virus Infection Market 

Growing Parainfluenza Virus Infection Incident Population

In 2023, the United States recorded the highest number of incident cases of parainfluenza virus infection among the 7MM. DelveInsight estimated approximately 2.7 million incident cases across the 7MM that year, with projections indicating a continued increase throughout the forecast period (2024–2034). The increasing burden of infection, particularly in vulnerable populations such as children and immunocompromised individuals, highlights the urgent need for effective, targeted treatments beyond supportive care.

Current Standard of Care and Market Size

In 2023, the Parainfluenza Virus Infection treatment market across the 7MM was valued at approximately USD 259 million, primarily driven by supportive care and symptomatic treatment. Corticosteroids are occasionally used for conditions like croup, but no specific antivirals are currently approved for PIV, underscoring a significant unmet medical need in this space. Market growth is anticipated as emerging therapies target this therapeutic gap.

Emerging Antiviral Candidates

Novel therapies in development, such as DAS181 and ALVR106, aim to redefine the treatment landscape for parainfluenza virus infection. DAS181, a recombinant sialidase fusion protein developed by Ansun Biopharma, works by preventing viral entry into respiratory epithelial cells and has shown broad-spectrum antiviral activity, including against PIV. ALVR106, an investigational multivirus-specific T-cell therapy by AlloVir, demonstrated preclinical activity against PIV and other respiratory viruses but was discontinued in early-phase trials. Despite setbacks, these emerging therapies reflect growing scientific interest and investment in this underserved area.

Expected Growth of Parainfluenza Virus Infection Market

In 2023, the parainfluenza virus infection treatment market across the 7MM generated nearly USD 259 million, primarily driven by standard of care. As the incident population increases and novel therapies continue development, the overall market size is anticipated to grow throughout the forecast period. The introduction of targeted antiviral agents could significantly shift the current treatment dynamics and address a long-standing unmet medical need.

DelveInsight’s “Parainfluenza Virus Infection Market Insights, Epidemiology, and Market Forecast – 2034” report delivers an in-depth understanding of the Parainfluenza Virus Infection, historical and forecasted epidemiology and the Parainfluenza Virus Infection market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

The Parainfluenza Virus Infection Treatment Market Report provides current treatment practices, market share of individual therapies, and current and forecasted 7MM, Parainfluenza Virus Infection market size from 2020 to 2034. The report also covers current Parainfluenza Virus Infection treatment market practices/algorithms and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.

Parainfluenza Virus Infection Treatment Market: Understanding and Algorithm

Parainfluenza virus (PIV) infection is a respiratory illness caused by one of four types of parainfluenza viruses: PIV-1, PIV-2, PIV-3, and PIV-4. These viruses belong to the Paramyxoviridae family and primarily affect the respiratory tract, leading to various respiratory infections such as the common cold, croup, bronchiolitis, and pneumonia. The causes of PIV infection involve transmission through respiratory droplets expelled when an infected person coughs, sneezes, or talks. Additionally, indirect transmission can occur through contact with contaminated surfaces.

Symptoms of PIV infection vary depending on the type and severity of the illness but commonly include symptoms of the common cold such as runny nose, cough, sore throat, and fever. In more severe cases, symptoms may include difficulty breathing, wheezing, and chest pain.

Parainfluenza Virus Infection Diagnosis

Diagnosis of PIV infection involves clinical evaluation, including a review of symptoms and medical history, as well as laboratory tests such as PCR or antigen detection tests on respiratory specimens. These tests can detect the presence of parainfluenza virus genetic material or antigens. Differential diagnosis may be necessary to distinguish PIV infection from other respiratory viruses with similar symptoms.

Further details related to country-based variations are provided in the report

Parainfluenza virus infection Treatment

Treatment for PIV infection is primarily supportive and focuses on relieving symptoms. This may include rest, adequate hydration, fever-reducing medications, and humidified air to alleviate respiratory symptoms. In severe cases, especially in immunocompromised individuals, antiviral medications such as ribavirin may be considered. However, their efficacy is uncertain, and they are not routinely recommended.

Parainfluenza Virus Infection Epidemiology

As the market is derived using the patient-based model, the Parainfluenza virus infection epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by Total Incident Cases of Parainfluenza virus infection, Serotype-specific Incident Cases of Parainfluenza Virus, Gender-specific Incident Cases of Parainfluenza Virus, and Age-specific Incident Cases of Parainfluenza Virus in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain) and the United Kingdom, and Japan, from 2020 to 2034.

• According to DelveInsight estimations, 2,709,923 Cases of Parainfluenza virus infection were found in 2023 in the 7MM.
• As per DelveInsight’s estimations, the total number of Parainfluenza Virus Infection Incident Cases in the United States were 1,456,399 in 2023 and are projected to increase during the forecast period.
• According to DelveInsight’s estimates, the total Parainfluenza Virus Infection Incident Cases in EU4 and the UK were found to be 991,115 in 2023. The highest proportion of parainfluenza virus infection cases was reported in Spain among the EU4 countries, while the least number of cases was found in the UK.
• The estimates show the number of parainfluenza virus infection cases in Japan was found to be approximately 262,409 in 2023, which is estimated to increase by 2034.

Parainfluenza Virus Infection Drug Chapters

The drug chapter segment of the Parainfluenza Virus Infection therapeutics market report encloses a detailed analysis of Parainfluenza Virus Infection marketed drugs and late-stage (Phase III and Phase II) Parainfluenza Virus Infection pipeline drugs. It also understands Parainfluenza Virus Infection clinical trials details, expressive pharmacological action, agreements and collaborations, approval, and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

Parainfluenza Virus Infection Emerging Drugs

• DAS181: Ansun Biopharma

DAS181 is a first-in-class recombinant sialidase protein that is designed to remove sialic acids located on the surface of epithelial cells lining the human respiratory tract. These sialic acids are naturally present on cell surfaces and are needed by some viruses for viral entry into cells. Cleavage of sialic acid inactivates the mechanism for viral entry and infection, interrupting the virus lifecycle and giving patients the chance to recover. DAS181 has demonstrated antiviral activity against three of the four major respiratory viruses, influenza virus (IFV), parainfluenza virus (PIV), and metapneumovirus (MPV), as well as human enterovirus-68 (EV-68).

• ALVR106: AlloVir

ALVR106 is an allogeneic, off-the-shelf, multivirus-specific VST investigational therapy designed to target infections and diseases caused by the respiratory syncytial virus (RSV), influenza, parainfluenza virus (PIV), and human metapneumovirus (hMPV). In vitro data demonstrate that ALVR106 has antiviral activity against each of the targeted viruses with minimal or no activity against non-virus-infected cells. (AlloVir, 2024). It is being developed in Phase I/II of clinical trials as per the company’s pipeline; however, the trial evaluating it was terminated before its completion as part of a strategic sponsor decision. The preclinical data of ALVR106 supports the potential for antiviral benefit and safety of ALVR106 when administered to patients.

Note: Detailed emerging therapies assessment will be provided in the final report of Parainfluenza Virus Infection

Parainfluenza Virus Infection Market Outlook

Presently, the primary approach to treating Parainfluenza Virus Infection involves supportive care, except for croup, where corticosteroids have been identified as beneficial. Novel Parainfluenza Virus Infection Drugs like DAS181 show promise for treating severe cases in immunocompromised patients and are currently undergoing development. Despite continuous endeavors, effective treatment options for Parainfluenza Virus Infection remain lacking, with no approved medications addressing this critical gap in care. Specifically, there is still no FDA-approved cure or antiviral medication designated for treating Parainfluenza Virus Infection.

Most cases of Parainfluenza Virus Infection tend to resolve without requiring targeted medical treatment. Nonetheless, supportive strategies such as adequate rest, hydration, and the use of over-the-counter medications to relieve symptoms may be recommended. In severe cases or among individuals with weakened immune systems, antiviral medications or hospitalization may be necessary. Additionally, Ribavirin is sometimes administered off-label for treating PIV infections due to its in vitro activity. However, its effectiveness is subject to debate, as there is a lack of data from randomized trials.

• The Parainfluenza Virus Infection Therapeutics Market is expected to experience positive growth.
• The total Parainfluenza Virus Infection Market Size in the 7MM was around USD 259 million in 2023. This is estimated to increase by 2034 at a significant CAGR.
• Among the 7MM, the US captured the highest Parainfluenza Virus Infection Market in 2023, covering a total of 68% market, followed by EU4 and the UK, which is anticipated to grow during the forecast period (2024–2034).
• In 2023, EU4 and the UK captured nearly 23% of the total Parainfluenza Virus Infection Drugs Market in the 7MM.
• Japan secured the second largest Parainfluenza Virus Infection drugs market share across all 7MM, and it is anticipated to increase by 2034.

KOL Views

To keep up with current market trends, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate the secondary research. Industry Experts were contacted for insights on Parainfluenza Virus Infection evolving treatment landscape, patient reliance on conventional therapies, patient therapy switching acceptability, and drug uptake along with challenges related to accessibility, including KOL from Department of Emergency Medicine, State University of New York at Stony Brook Health Sciences Center, US, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, US, Comprehensive Heart Failure Centre Würzburg and Department of Internal Medicine, University and University Hospital Würzburg, Germany, Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan and others.

DelveInsight’s analysts connected with 50+ KOLs to gather insights; however, interviews were conducted with 15+ KOLs in the 7MM. Their opinion helps to understand and validate current and emerging therapies and treatment patterns or Parainfluenza Virus Infection market trends. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the market and the unmet needs.

Parainfluenza Virus Infection Drugs Market: Qualitative Analysis

We perform Qualitative and market Intelligence analysis using various approaches, such as SWOT analysis. In the SWOT analysis, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided. These pointers are based on the Analyst’s discretion and assessment of the patient burden, cost analysis, and existing and evolving treatment landscape.

Parainfluenza Virus Infection Therapeutics Market Access and Reimbursement

The high cost of therapies for the treatment is a major factor restraining the growth of the drug market. Because of the high cost, the economic burden is increasing, leading the patient to escape from proper treatment. The report further provides detailed insights on the country accessibility and reimbursement scenarios, cost-effectiveness scenario of approved therapies, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.

Parainfluenza Virus Infection Therapeutics Market Report Scope

• The Parainfluenza Virus Infection therapeutics market report covers a segment of key events, an executive summary, descriptive overview, explaining its causes, signs and symptoms, and currently available therapies.
• Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, disease progression, and treatment guidelines.
• Additionally, a comprehensive overview of existing therapies, along with an analysis of how the introduction of generic drugs will impact the current Parainfluenza Virus Infection treatment market landscape.
• A detailed review of the Parainfluenza Virus Infection drugs market, historical and forecasted Parainfluenza Virus Infection treatment market size, Parainfluenza Virus Infection drugs market share by therapies, detailed assumptions, and rationale behind the approach is included in the report covering the 7MM drug outreach.
• The Parainfluenza Virus Infection therapeutics market report provides an edge while developing business strategies, by understanding trends, through SWOT analysis and expert insights/KOL views, patient journey, and treatment preference that help shape and drive the 7MM Parainfluenza Virus Infection drugs market.

Parainfluenza Virus Infection Therapeutics Market Report Insights

• Patient-based Parainfluenza Virus Infection Market Forecasting
• Therapeutic Approaches
• Parainfluenza Virus Infection Market Size and Trends
• Existing and Future Parainfluenza Virus Infection Drugs Market Opportunity

Parainfluenza Virus Infection Therapeutics Market Report Key Strengths

• 11 years Parainfluenza Virus Infection Market Forecast
• The 7MM Coverage
• Parainfluenza Virus Infection Epidemiology Segmentation
• Parainfluenza Virus Infection Drugs Uptake
• Key Parainfluenza Virus Infection Market Forecast Assumptions

Parainfluenza Virus Infection Therapeutics Market Report Assessment

• Current Parainfluenza Virus Infection Treatment Market Practices
• Parainfluenza Virus Infection Unmet Needs
• Parainfluenza Virus Infection Drugs Market Attractiveness
• Qualitative Analysis (SWOT Analysis)

Key Questions

Parainfluenza Virus Infection Treatment Market Insights

• What was the Parainfluenza Virus Infection treatment market size, the Parainfluenza Virus Infection market size by therapies, and Parainfluenza Virus Infection drugs market share (%) distribution in 2020, and how would it all look in 2034? What are the contributing factors for this growth?
• What unmet needs are associated with the current treatment market of Parainfluenza Virus Infection?
• Which drug is going to be the largest contributor by 2034?
• What are the pricing variations among different geographies for off-label therapies?
• How would the market drivers, barriers, and future opportunities affect the market dynamics and subsequent analysis of the associated trends?

Parainfluenza Virus Infection Epidemiology Insights

• What are the disease risk, burdens, and Parainfluenza Virus Infection Unmet Needs? What will be the growth opportunities across the 7MM concerning the patient population of Parainfluenza Virus Infection?
• What is the historical and forecasted Parainfluenza Virus Infection patient pool in the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan?
• What factors are affecting the diagnosis of the indication?

Current Parainfluenza Virus Infection Treatment Market Scenario, Marketed Drugs, and Emerging Therapies

• What are the current options for treating Parainfluenza Virus Infection? What are the current guidelines for treating Parainfluenza Virus Infection in the US and Europe?
• How many companies are developing therapies for Parainfluenza Virus Infection?
• How many emerging therapies are in the mid-stage and late stage of development Parainfluenza Virus Infection?
• What are the key designations that have been granted for the emerging therapies for Parainfluenza Virus Infection?
• What is the cost burden of approved therapies on the patient?
• Patient acceptability in terms of preferred treatment options as per real-world scenarios?
• What are the country-specific accessibility issues of expensive, recently approved therapies? Focus on reimbursement policies.
• What are the 7MM historical and forecasted Parainfluenza Virus Infection Drugs Market?

Reasons to Buy

• The Parainfluenza Virus Infection Therapeutics Market report will help develop business strategies by understanding the latest trends and changing treatment dynamics driving the parainfluenza virus infection drugs market.
• Insights on patient burden/disease Parainfluenza Virus Infection Incidence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• To understand the existing Parainfluenza Virus Infection Drugs Market opportunity in varying geographies and the growth potential over the coming years.
• Distribution of historical and current patient share based on real-world prescription data along with reported sales of approved products in the US, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan.
• Identifying strong upcoming players in the Parainfluenza Virus Infection Market will help devise strategies that will help get ahead of competitors.
• Detailed analysis, ranking of class-wise potential current, and emerging therapies under the conjoint analysis section to provide visibility around leading classes.
• Highlights of Access and Reimbursement policies of approved therapies, barriers to accessibility of off-label expensive therapies, and patient assistance programs.
• To understand the perspective of Key Opinion Leaders around the accessibility, acceptability, and compliance-related challenges of existing treatment to overcome barriers in the future.
• Detailed insights on the unmet need of the existing market so that the upcoming players can strengthen their development and launch strategy.

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