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Uncomplicated Urinary Tract Infection Epidemiology Forecast

DelveInsight’s ‘Uncomplicated Urinary Tract Infection (uUTI) - Epidemiology Forecast to 2030’ report delivers an in-depth understanding of the disease, historical and forecasted Uncomplicated Urinary Tract Infection epidemiology in the 7MM, i.e., the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

Geographies Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study Period: 2018–2030

Uncomplicated Urinary Tract Infection (uUTI) Understanding

A Urinary Tract Infection (UTI) (also known as a bladder infection) is a common condition that occurs when bacteria migrate into the usually sterile urinary tract and multiply. Urinary Tract Infection is caused by a range of pathogens, but most commonly by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, and Staphylococcus saprophyticus. A UTI can develop in any part of the urinary tract, including the urethra, bladder, ureters, or kidneys. Urinary tract infection are primarily caused by gram-negative bacteria, but gram-positive pathogens may also be involved.

 

Urinary Tract Infection is classified into complicated or uncomplicated, depending on the presence or absence of structural abnormality, pregnancy, sex, and renal obstructions. Uncomplicated Urinary Tract Infection typically affects individuals who are otherwise healthy and have no structural or neurological urinary tract abnormalities; these infections are differentiated into lower urinary tract infection (cystitis) and upper urinary tract infection (pyelonephritis). Several risk factors are associated with cystitis, including female gender, a prior urinary tract infection, sexual activity, vaginal infection, diabetes, obesity, and genetic susceptibility.

 

Recurrent Urinary Tract Infection is defined as at least two infections within six months or at least three infections within one year. The recurrence of a urinary tract infection may be relapse (i.e., caused by the same uropathogen) or re-infection (i.e., caused by different uropathogens). Most recurrences are likely re-infection rather than relapse. Recurrent urinary tract infection in women is caused by uropathogens that adhere well to the uroepithelial cells. Recurrent urinary tract infection may occur in women of any age, and there may be a genetic predisposition because some women are more likely to develop subsequent infections after the first episode of Urinary Tract Infection.

 

Uncomplicated Urinary Tract Infection (uUTI) Diagnosis

Frequent sexual intercourse is one of the biggest urinary tract infection risk factors for younger women. For menopausal women, however, physical changes such as the thinning of vaginal tissue, difficulty fully emptying the bladder, incontinence, and pelvic organ prolapse are the main culprits. In addition, during menopause, the body produces less estrogen, a hormone that, among other functions, helps keep the bacteria levels in the lining of the bladder and urethra healthy.

 

The gold standard for UTI diagnosis is the urine examination, including quantitative urine culture and its assessment, with appropriate clinical examinations and typical symptom assessment. A negative test for nitrite/leukocytes may be considered to rule out UTI with sufficient certainty in patients with a low pretest probability. The detection of blood, leukocytes, and nitrite independently increases the likelihood of the presence of a UTI. Diagnosis of Uncomplicated UTI includes clinical examination based on a focused history of lower urinary tract symptoms and the absence of vaginal discharge or irritation. Further lab tets to confirm the diagnosis includes Urinalysis, Urine microscopy, and Urine culture. Other than this, some imaging and other tests can also be used, such as Cystoscopy and Ureteroscopy.

Epidemiology Perspective by DelveInsight

The Uncomplicated Urinary Tract Infection epidemiology division provides insights about historical and current Uncomplicated Urinary Tract Infection patient pool and forecasted trends for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

 

Key Findings

In the year 2020, the total occurrence-specific cases of Uncomplicated Urinary Tract Infection was 35.3 million cases in the 7MM which are expected to grow during the forecast period, i.e., 2021–2030.

 

The disease epidemiology covered in the report provides historical as well as forecasted Uncomplicated Urinary Tract Infection epidemiology [segmented as Total Occurrence-specific Cases of Uncomplicated Urinary Tract Infection, Total Diagnosed Cases of Uncomplicated Urinary Tract Infection, Total Age-specific Cases of Uncomplicated Urinary Tract Infection, Total Pathogen-specific Cases of Uncomplicated Urinary Tract Infection, and Total Treated cases (across lines) of Uncomplicated Urinary Tract Infection] in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2018 to 2030.

Country Wise- Uncomplicated Urinary Tract Infection Epidemiology

  • Estimates show that the highest cases of Uncomplicated Urinary Tract Infection in the 7MM were in the United States, followed by Japan, Italy, France, the United Kingdom, Germany, and Spain in 2020.
  • In the United States, the total number of occurrence-specific cases of Uncomplicated Urinary Tract Infection was 14.7 million cases in the year 2020 which are expected to grow during the study period, i.e., 2018–2030.
  • In the year 2020, the total occurrence-specific cases of Uncomplicated Urinary Tract Infection were 13.9 million cases in EU-5 which are expected to grow during the study period, i.e., 2018–2030.
  • In Japan, the total number of occurrence-specific cases of Uncomplicated Urinary Tract Infection was 6.7 million cases in the year 2020 which are expected to grow during the study period, i.e., 2018–2030.
  • In the 7MM, the total age-specific cases of Uncomplicated Urinary Tract Infection were 5.0 million, 6.8 million, 4.3 million, and 3.3 million cases for the age group 18–29, 30–49, 50–69, and ≥70 years, respectively in 2020.
  • In the 7MM, the total pathogen-specific cases of Uncomplicated Urinary Tract Infection were 14.5 million, 1.2 million, 1.2 million, 1.0 million, and 1.5 million cases for the pathogens Uropathogenic Escherichia coli (UPEC), Klebsiella pneumonia, Staphylococcus saprophyticus, Enterococcus faecalis, and Others, respectively in 2020.

Scope of the Report

  • The Uncomplicated Urinary Tract Infection report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis, and treatment patterns.
  • The Uncomplicated Urinary Tract Infection Report and Model provide an overview of the risk factors and global trends of Uncomplicated Urinary Tract Infection in the seven major markets (7MM: The United States, Germany, France, Italy, Spain, and the United Kingdom, and Japan)
  • The report provides insight about the historical and forecasted patient pool of Uncomplicated Urinary Tract Infection in seven major markets covering the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
  • The report helps to recognize the growth opportunities in the 7MM concerning the patient population.
  • The report assesses the disease risk and burden and highlights the unmet needs of Uncomplicated Urinary Tract Infection.
  • The report provides the segmentation of the Uncomplicated Urinary Tract Infection epidemiology by total occurrence-specific cases in the 7MM.
  • The report provides the segmentation of the Uncomplicated Urinary Tract Infection epidemiology by total diagnosed cases in the 7MM.
  • The report provides the segmentation of the Uncomplicated Urinary Tract Infection epidemiology by total age-specific cases in the 7MM.
  • The report provides the segmentation of the Uncomplicated Urinary Tract Infection epidemiology by total pathogen-specific cases in the 7MM.
  • The report provides the segmentation of the Uncomplicated Urinary Tract Infection epidemiology by total treated cases (across lines) in the 7MM.

Report Highlights

  • 10-Year Forecast of Uncomplicated Urinary Tract Infection epidemiology
  • 7MM Coverage
  • Total Occurrence-specific Cases of Uncomplicated Urinary Tract Infection
  • Total Diagnosed Cases of Uncomplicated Urinary Tract Infection
  • Total Age-Specific Cases of Uncomplicated Urinary Tract Infection
  • Total Pathogen-Specific Cases of Uncomplicated Urinary Tract Infection
  • Total Treated Cases (across lines) of Uncomplicated Urinary Tract Infection

KOL-Views

We interview KOL’s and SME's opinion through primary research to fill the data gaps and validate our secondary research. The opinion helps to understand the total patient population and current treatment pattern. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the indications.

Key Questions Answered

  • What will be the growth opportunities in the 7MM concerning the patient population of Uncomplicated Urinary Tract Infection?
  • What are the key findings of the Uncomplicated Urinary Tract Infection epidemiology across the 7MM and which country will have the highest number of patients during the study period (2018–2030)?
  • What would be the total number of patients of Uncomplicated Urinary Tract Infection across the 7MM during the study period (2018–2030)?
  • Among the EU5 countries, which country will have the highest number of patients during the study period (2018–2030)?
  • At what CAGR the patient population is expected to grow in the 7MM during the study period (2018–2030)?
  • What are the various recent and upcoming events which are expected to improve the diagnosis of Uncomplicated Urinary Tract Infection?

Reasons to buy

  • The Uncomplicated Urinary Tract Infection Epidemiology report will allow the user to -
  • Develop business strategies by understanding the trends shaping and driving the global Uncomplicated Urinary Tract Infection market
  • Quantify patient populations in the global Uncomplicated Urinary Tract Infection market to improve product design, pricing, and launch plans
  • Organize sales and marketing efforts by identifying the gender that presents the best opportunities for Uncomplicated Urinary Tract Infection therapeutics in each of the markets covered
  • Understand the magnitude of Uncomplicated Urinary Tract Infection population by its pathogen-specificity
  • The Uncomplicated Urinary Tract Infection epidemiology report and model were written and developed by Masters and Ph.D. level epidemiologists
  • The Uncomplicated Urinary Tract Infection Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over an 10-year forecast period using reputable sources

Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of disease by the segmentation
  • Factors driving growth in a specific patient population

1. Key Insights

2. Report Introduction

3. Executive Summary of Uncomplicated Urinary Tract Infection (uUTI)

3.1. Key Events

4. Epidemiology Methodology

5. Disease Background and Overview

5.1. Introduction

5.2. Types of UTI

5.3. Signs and Symptoms of Uncomplicated UTI

5.4. Risk Factors and Causes of Uncomplicated UTI

5.5. Pathogenesis of UTI

5.6. Complications of UTI

6. Diagnosis of Uncomplicated UTI

6.1. Diagnostic algorithm

6.2. Clinical Examination

6.3. Lab Tests

6.4. Imaging and other tests

6.4.1. Cystoscopy

6.4.2. Ureteroscopy

6.5. Differential diagnosis

7. Prevention of UTI

8. Diagnostic Guidelines

8.1. European Association of Urology (EAU) Urological Infections Diagnostic Guidelines

8.2. American Urological Association (AUA) Guidelines

8.3. Guidelines of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC)

9. Epidemiology and Patient Population

9.1. Key Findings

9.2. Epidemiology of Uncomplicated Urinary Tract Infection (uUTI)

9.3. Epidemiology Scenario

9.3.1. Total Occurrence-specific Cases of Uncomplicated Urinary Tract Infection

9.3.2. Total Diagnosed Cases of Uncomplicated Urinary Tract Infection

9.3.3. Total Age-specific Cases of Uncomplicated Urinary Tract Infection

9.3.4. Total Pathogen-specific Cases of Uncomplicated Urinary Tract Infection

9.3.5. Total Treated Cases (across lines) of Uncomplicated Urinary Tract Infection

10. SWOT Analysis

11. Appendix

11.1. Bibliography

11.2. Report Methodology

12. DelveInsight Capabilities

13. Disclaimer

14. About DelveInsight

List of Table

Table 1: Summary of uUTI Market and Epidemiology (2018–2030)

Table 2: Key classifications of UTI

Table 3: Cut-off values (colony forming units [CFU]/mL) for the diagnosis of UTI

Table 4: Diagnostic recommendations for Uncomplicated cystitis

Table 5: Diagnostic recommendations for Recurrent UTI

Table 6: Diagnostic recommendations for Uncomplicated pyelonephritis

Table 7: Diagnostic recommendations for recurrent UTI (rUTI)

Table 8: Total Occurrence-specific Cases of Uncomplicated Urinary Tract Infection (in Thousands) (2018–2030)

Table 9: Total Diagnosed Cases of Uncomplicated Urinary Tract Infection (in Thousands) (2018–2030)

Table 10: Total Age-specific Cases of Uncomplicated Urinary Tract Infection (in Thousands) (2018–2030)

Table 11: Total Pathogen-specific Cases of Uncomplicated Urinary Tract Infection (in Thousands) (2018–2030)

Table 12: Total Treated Cases of Uncomplicated Urinary Tract Infection (in Thousands) (2018–2030)

List of Figures

Figure 1: Epidemiology and Market Methodology

Figure 2: Symptoms of Uncomplicated UTI

Figure 3: Risk factors of UTI

Figure 4: Pathogenesis of UTI

Figure 5: Diagnostic algorithm for UTI

Figure 6: Total Occurrence-specific Cases of Uncomplicated Urinary Tract Infection in the 7MM (2018–2030)

Figure 7: Total Diagnosed Cases of Uncomplicated Urinary Tract Infection in the 7MM (2018–2030)

Figure 8: Total Age-specific Cases of Uncomplicated Urinary Tract Infection in the 7MM (2018–2030)

Figure 9: Total Pathogen-specific Cases of Uncomplicated Urinary Tract Infection in the 7MM (2018–2030)

Figure 10: Total Treated Cases (across the line) of Uncomplicated Urinary Tract Infection in the 7MM (2018–2030)

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