Venous Thromboembolism Epidemiology

• The burden of venous thromboembolism (VTE) is expected to increase substantially over the coming decades, with projections indicating that the number of affected adults in the United States could nearly double.
• The concerns regarding bleeding complications contribute to the underutilization of anticoagulant therapy in clinical practice, leaving some high-risk patients vulnerable to potentially life-threatening thrombotic events.
• The clinical presentation of VTE is often nonspecific and can overlap with other cardiovascular, respiratory, or musculoskeletal conditions. Symptoms such as leg pain, swelling, chest pain, and shortness of breath may be overlooked or attributed to alternative causes, leading to delayed diagnosis and treatment.

Venous Thromboembolism Epidemiology Forecast in the 7MM

• 2025 Incident of Venous Thromboembolism: ~XX
• 2036 Projected Venous Thromboembolism Incident Cases: ~XX
• Venous Thromboembolism Growth Rate (2026–2036): ~XX% CAGR

DelveInsight's ‘Venous Thromboembolism Epidemiology Forecast 2036’ report delivers an in-depth understanding of venous thromboembolism, historical and forecasted epidemiology, in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.

Venous Thromboembolism Understanding and Diagnosis Algorithm

Venous Thromboembolism Overview

Venous thromboembolism is a vascular disorder that encompasses DVT and pulmonary embolism. DVT occurs when a blood clot forms in the deep veins, most commonly in the lower extremities, while pulmonary embolism develops when part of the clot dislodges and travels to the lungs, potentially causing life-threatening complications. Venous thromboembolism is a major cause of morbidity and mortality worldwide and is associated with risk factors such as advanced age, prolonged immobility, surgery, hospitalization, cancer, obesity, pregnancy, inherited thrombophilia, and certain chronic medical conditions. The disease imposes a substantial healthcare burden due to recurrent events, long-term complications, and the need for ongoing anticoagulation therapy.

Further details are provided in the report.

Venous Thromboembolism Diagnosis

Diagnosis of venous thromboembolism involves a combination of clinical assessment, laboratory testing, and imaging studies. Patients with DVT may present with symptoms such as unilateral leg swelling, pain, tenderness, and redness, whereas pulmonary embolism commonly manifests as shortness of breath, chest pain, tachycardia, and, in severe cases, hemodynamic instability. Diagnostic evaluation often includes clinical prediction tools, such as the Wells score, along with D-dimer testing to assess the likelihood of thrombosis. Confirmatory imaging studies include compression ultrasonography for DVT and computed tomography pulmonary angiography (CTPA) for pulmonary embolism, which remain the standard diagnostic modalities in clinical practice.

Further details are provided in the report.

Venous Thromboembolism Epidemiology

Key Findings from Venous Thromboembolism Epidemiological Analysis and Forecast 

• In the United States, up to 900,000 people develop venous thromboembolism annually, resulting in an estimated 60,000–100,000 deaths each year and substantial long-term complications among survivors. 
• According to secondary analysis, increasing age is associated with a significant increase in risk, with an annual incidence of 1 per 100, in those over 80 years of age.
• Half of all venous thromboembolism episodes are associated with hospitalization and/or surgery in the preceding 3 months.
• Women are at a higher risk of venous thromboembolism during younger adulthood due to factors such as the use of combined hormonal contraceptives and pregnancy. 
• As per Thrombosis UK, 1 in 4 deaths are related to blood clots.

Scope of the Report

• The report covers a segment of a descriptive overview of venous thromboembolism, explaining its causes, signs and symptoms, and pathogenesis.
• Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of the diagnosis rate, and disease progression.

Report Insights

Venous Thromboembolism Patient Population Forecast

Report Key Strengths

• Epidemiology‑based (Epi‑based) Bottom‑up Forecasting
• 11-year Forecast 
• Patient Burden Trends (by geography)

FAQs

• What are the disease risks, burdens, and unmet needs of venous thromboembolism? What will be the growth opportunities across the 7MM concerning the patient population with venous thromboembolism?
• What is the historical and forecasted venous thromboembolism patient pool in the US, EU4 (Germany, France, Italy, and Spain), the UK, and Japan?

Reasons to Buy

• Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• To understand key opinion leaders’ perspectives on the diagnostic challenges to overcome barriers in the future.
• Detailed insights into various factors hampering disease diagnosis and other existing diagnostic challenges.