Metastatic Prostate Cancer Epidemiology
- Prostate cancer is the third most prevalent type of cancer in the US and the fourth most common worldwide.
- Prostate cancer is most frequently diagnosed among men aged 65–74 years; the median age at diagnosis is 66 years.
- Around 45% of the patients had mCSPC/mHSPC, and around 55% had mCRPC.
- Studies show a continued increase in the incidence of distant-stage prostate cancer in the United States. The percentage of distant-stage prostate cancer increased from 4% in 2003 to 8% in 2017
- The global burden of prostate cancer continues to increase due to population aging, improved screening practices, and enhanced diagnostic technologies. Recent published estimates indicate that more than 1.4–1.5 million new prostate cancer cases are diagnosed globally each year, making it the second most frequently diagnosed cancer in men worldwide. Incidence rates are rising particularly in older men and in countries with widespread PSA-based screening programs.
Metastatic Prostate Cancer Epidemiology Forecast in the 7MM
- 2025 Prevalent Cases of Metastatic Prostate Cancer : ~315,000
- Prostate Cancer Growth Rate (2026–2036): XX% CAGR
DelveInsight's ‘Metastatic Prostate Cancer Epidemiology Forecast 2036’ report delivers an in-depth understanding of the Metastatic Prostate Cancer, historical and forecasted epidemiology, in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.
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Study Period
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2022–2036
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Historical Year
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2022–2025
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Forecast Period
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2026–2036
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Base Year
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2026
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Geographies Covered
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Metastatic Prostate Cancer Epidemiology CAGR
(Forecast period)
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XX% (2026–2036)
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Metastatic Prostate Cancer Epidemiology Segmentation Analysis
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Patient Burden Assessment
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Total Prevalent Cases of Prostate Cancer
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Five-year Prevalent Cases of Prostate Cancer
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Total Prevalent Cases of Prostate Cancer Cases by Clinical Stages
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Age-specific Cases of Prostate Cancer
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Total Prevalent Cases of Metastatic Prostate Cancer
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Metastatic Prostate Cancer Understanding and Diagnosis Algorithm
Metastatic Prostate Cancer Overview and Diagnosis
Metastatic prostate cancer is an advanced stage of prostate malignancy in which cancer cells spread beyond the prostate gland to distant sites, most commonly the bone, lymph nodes, liver, and lungs. It typically progresses from localized disease to metastatic hormone-sensitive prostate cancer (mHSPC) and eventually to metastatic castration-resistant prostate cancer (mCRPC). Diagnosis is based on a combination of PSA testing, imaging, and histopathology. Elevated prostate-specific antigen (PSA) levels often initiate further evaluation, although PSA alone is not diagnostic of metastatic disease.
Further details are provided in the report.
Metastatic Prostate Cancer Diagnosis
Diagnosis is based on a combination of PSA testing, imaging, and histopathology. Elevated prostate-specific antigen (PSA) levels often initiate further evaluation, although PSA alone is not diagnostic of metastatic disease. Imaging modalities such as bone scans, CT/MRI, and PSMA PET/CT are central to detecting and staging metastatic spread, with PSMA PET/CT offering superior sensitivity. Definitive diagnosis is confirmed via prostate biopsy, while metastatic lesions may be biopsied in select cases for further characterization. Disease classification into mHSPC or mCRPC is determined by response to ADT and testosterone suppression levels, which directly guides treatment strategy.
Further details are provided in the report.
Metastatic Prostate Cancer Epidemiology
Key Findings from Metastatic Prostate Cancer Epidemiological Analysis and Forecast
- According to DelveInsight’s estimates, in 2025, the total number of prevalent cases of metastatic prostate cancer in the 7MM were ~315,000.
- Based on DelveInsight's estimates in 2025, the US had ~3,864,000 prevalent cases of prostate cancer. These are expected to rise due to the growing geriatric population and advancements in diagnostic capabilities during the forecast period (2026−2036).
- The five-year prevalent cases of prostate cancer in the US was approximately ~1,157,000 in 2025.
- In 2025, in the US, the total cases of mCSPC were approximately ~72,500.
- According to the SEER, prostate cancer is most frequently diagnosed among men aged 65–74 years; the median age at diagnosis is 66 years. The most number of cases was found in people aged between 65 and 74 years, followed by 55–64 years and 75–84 years.
Scope of the Report
- The report covers a segment of a descriptive overview of hand eczema, explaining their causes, signs and symptoms, and pathogenesis.
- Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of the diagnosis rate, and disease progression.
Report Insights
Metastatic Prostate Cancer Patient Population Forecast
Report Key Strengths
- Epidemiology‑based (Epi‑based) Bottom‑up Forecasting
- 11-year Forecast
- Patient Burden Trends (by geography)
FAQs
- What are the disease risks, burdens, and unmet needs of hand eczema? What will be the growth opportunities across the 7MM concerning the patient population with hand eczema?
- What is the historical and forecasted hand eczema patient pool in the US, EU4 (Germany, France, Italy, and Spain), the UK, and Japan?
Reasons to Buy
- Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
- To understand key opinion leaders’ perspectives around the diagnostic challenges to overcome barriers in the future.
- Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.
1 Key Insights
2 Report Introduction
3 Executive Summary
4 Epidemiology Forecast Methodology
5 Metastatic Prostate Cancer Epidemiology Overview at a Glance
5.1 Patient Share (%) Distribution by Country in 2025 in the 7MM
5.2 Patient Share (%) Distribution by Country in 2036 in the 7MM
6 Disease Background And Overview of Metastatic Prostate Cancer
6.1 Signs and Symptoms of Prostate Cancer
6.2 Risk Factors and Causes of Prostate Cancer
6.3 Stages of Prostate Cancer
6.4 Pathophysiology of Prostate Cancer
6.5 Diagnosis of Prostate Cancer
6.5.1 Tests to Diagnose Prostate Cancer
7 Patient Journey of Metastatic Prostate Cancer
8 Epidemiology and Patient Population of Metastatic Prostate Cancer
8.1 Key Findings
8.2 Assumptions and Rationale: The 7MM
8.2.1 Total Prevalent Cases of Prostate Cancer in the 7MM
8.3 The United States
8.3.1 Five-year Prevalent Cases of Prostate Cancer in the US
8.3.2 Total Prevalent Cases of Prostate Cancer by Clinical Stages in the US
8.3.3 Age-specific Cases of Prostate Cancer in the US
8.3.4 Total Prevalent Cases of Metastatic Prostate Cancer in the US
8.4 EU4 and the UK
8.4.1 Five-year Prevalent Cases of Prostate Cancer in EU4 and the UK
8.4.2 Total Prevalent Cases of Prostate Cancer by Clinical Stages in EU4 and the UK
8.4.3 Age-specific Cases of Prostate Cancer in EU4 and the UK
8.4.4 Total Prevalent Cases of Metastatic Prostate Cancer in EU4 and the UK
8.5 Japan
8.5.1 Five-year Prevalent Cases of Prostate Cancer in Japan
8.5.2 Total Prevalent Cases of Prostate Cancer by Clinical Stages in Japan
8.5.3 Age-specific Cases of Prostate Cancer in Japan
8..5.4 Total Prevalent Cases of Metastatic Prostate Cancer in Japan
9 KOL Views of Metastatic Prostate Cancer
10 Appendix
10.1 Bibliography
10.2 Report Methodology
11 DelveInsight Capabilities
12 Disclaimer
13 About DelveInsight
List of Tables:
List of Tables
Table 1: Summary of Prostate Cancer Epidemiology (2022–2036)
Table 2: Genetic Changes Associated with Prostate Cancer Tumorigenesis
Table 3: Gleason Score of Prostate Cancer
Table 4: Total Cases of Metastatic Prostate Cancer in the 7MM (2022–2036)
Table 5: Total Prevalent Cases of Prostate Cancer in the US (2022–2036)
Table 6: Total Diagnosed Prevalent Cases of Prostate Cancer in the US (2022–2036)
Table 7: Age-specific Cases of Prostate Cancer in the US (2022–2036)
Table 8: Total Diagnosed Cases of Prostate Cancer by Clinical Stages in the US (2022–2036)
Table 9: Total Metastatic Cases of Prostate Cancer in the US (2022–2036)
Table 10: Total Treated Cases of mCRPC in the US (2022–2036)
Table 11: Total Treated Cases of mCSPC/mHSPC in the US (2022–2036)
Table 12: Total Prevalent Cases of Prostate Cancer in EU4 and the UK (2022–2036)
Table 13: Total Diagnosed Prevalent Cases of Prostate Cancer in EU4 and the UK (2022–2036)
Table 14: Age-specific Cases of Prostate Cancer in the EU4 and the UK (2022–2036)
Table 15: Total Diagnosed Prevalent cases of Prostate Cancer by Clinical Stages in the EU4 and the UK (2022–2036)
Table 16: Total Cases of Metastatic Prostate Cancer in EU4 and the UK (2022–2036)
Table 17: Total Treated Cases of mCRPC in the EU4 and the UK (2022–2036)
Table 18: Total Treated Cases of mCSPC/mHSPC in EU4 and the UK (2022–2036)
Table 19: Total Prevalent Cases of Prostate Cancer in Japan (2022–2036)
Table 20: Total Diagnosed Cases of Prostate Cancer in Japan (2022–2036)
Table 21: Age-specific Cases of Prostate Cancer in Japan (2022–2036)
Table 22: Total Diagnosed Cases of Prostate Cancer by Clinical Stages in Japan (2022–2036)
Table 23: Total Metastatic Cases of Prostate Cancer in Japan (2022–2036)
Table 24: Total Treated Cases of mCRPC in Japan (2022–2036)
Table 25: Total Treated Cases of mCSPC/mHSPC in Japan (2022–2036)
List of Figures:
List of Figures
Figure 1: Prostate Cancer
Figure 2: Signs and Symptoms of Prostate Cancer
Figure 3: Risks Factors of Prostate Cancer
Figure 4: Pathophysiology of Prostate Cancer
Figure 5: Progression of Prostate Cancer and the Development of mCRPC
Figure 6: Diagnosis of Prostate Cancer
Figure 7: Global Heat Map of Prostate Cancer
Figure 8: Total Cases of Metastatic Prostate Cancer in the 7MM (2022–2036)
Figure 9: Total Prevalent Cases of Prostate Cancer in the US (2022–2036)
Figure 10: Total Diagnosed Prevalent Cases of Prostate Cancer in the US (2022–2036)
Figure 11: Age-specific Cases of Prostate Cancer in the US (2022–2036)
Figure 12: Total Diagnosed Cases of Prostate Cancer by Clinical Stages in the US (2022–2036)
Figure 13: Total Metastatic Cases of Prostate Cancer in the US (2022–2036)
Figure 14: Total Treated Cases of mCRPC in the US (2022–2036)
Figure 15: Total Treated Cases of mCSPC/mHSPC in the US (2022–2036)
Figure 16: Total Prevalent Cases of Prostate Cancer in EU4 and the UK (2022–2036)
Figure 17: Total Diagnosed Prevalent Cases of Prostate Cancer in EU4 and the UK (2022–2036)
Figure 18: Age-specific Cases of Prostate Cancer in EU4 and the UK (2022–2036)
Figure 19: Total Diagnosed Cases of Prostate Cancer by Clinical Stages in EU4 and the UK (2022–2036)
Figure 20: Total Cases of Metastatic Prostate Cancer in EU4 and the UK (2022–2036)
Figure 21: Total Treated Cases of mCRPC in EU4 and the UK (2022–2036)
Figure 22: Total Treated Cases of mCSPC/mHSPC in EU4 and the UK (2022–2036)
Figure 23: Total Prevalent Cases of Prostate Cancer in Japan (2022–2036)
Figure 24: Total Diagnosed Cases of Prostate Cancer in Japan (2022–2036)
Figure 25: Age-specific Cases of Prostate Cancer in Japan (2022–2036)
Figure 26: Total Diagnosed Cases of Prostate Cancer by Clinical Stages in Japan (2022–2036)
Figure 27: Total Metastatic Cases of Prostate Cancer in Japan (2022–2036)
Figure 28: Total Treated Cases of mCRPC in Japan (2022–2036)
Figure 29: Total Treated Cases of mCSPC/mHSPC in Japan (2022–2036)