NUCALA Market Report covers drugs, Mechanism of Action, Dosage and Administration, Route of Synthesis, Pharmacological Studies, including product Marketed Details

NUCALA Market Forecast, Sales Forecasting, Mechanism of Action

&ldquo;NUCALA Market Size, Forecast, and Drug Insight &ndash; 2032&rdquo; report provides comprehensive insights about NUCALA for <a href="https://www.delveinsight.com/report-store/nasal-polyposis-market">Nasal Polyposis</a> and <a href="https://www.delveinsight.com/report-store/asthma-market">Asthma</a> in the 7MM. A detailed picture of the NUCALA in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan, for the study period 2019&ndash;2032 is provided in this report, along with a detailed description of the NUCALA. The report provides insight about the NUCALA Mechanism of Action, dosage and administration, as well as research and development activity, including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments, inclusive of the NUCALA Market Forecast, analysis in the 7MM, descriptive analysis such as SWOT, analyst views, a comprehensive overview of market competitors, and a brief about emerging therapies.
<h2>NUCALA Drug Summary</h2>
GSK&rsquo;s NUCALA (<a href="https://www.delveinsight.com/report-store/mepolizumab-emerging-insight-and-market-forecast">Mepolizumab</a>) is the first IL-5 therapy approved as an add-on treatment in the US for adults with <a href="https://www.delveinsight.com/report-store/chronic-rhinosinusitis-with-nasal-polyps-market">chronic rhinosinusitis with nasal polyps</a> to target eosinophilic inflammation in adult patients 18 years of age and older with inadequate response to nasal corticosteroids. NUCALA was recently approved by the US FDA based on positive results from the pivotal Synapse study.&nbsp;
Mepolizumab is also approved for use in three other eosinophilic-driven diseases, the first indication being for patients with severe eosinophilic asthma aged 6 years and older. Additionally, mepolizumab was the first biologic therapy indicated for adults with eosinophilic granulomatosis with polyangiitis (EGPA) and also the first biologic to be approved for patients aged 12 years and older with hypereosinophilic syndrome (HES) (FDA, 2021). After the approval for CRSwNP, NUCALA has become the only treatment approved in the US for use in four eosinophil-driven diseases. NUCALA has contributed to giving one of the broadest portfolios to GSK in respiratory medicines (GSK, 2020)
Mepolizumab is an IL-5 antagonist (IgG1 kappa). IL-5 is the major cytokine responsible for the growth and differentiation, recruitment, activation, and survival of <a href="https://www.delveinsight.com/report-store/eosinophilia-market">eosinophils</a>. Mepolizumab binds to IL-5 with a dissociation constant of 100 pM, inhibiting the bioactivity of IL-5 by blocking its binding to the alpha chain of the IL-5 receptor complex expressed on the eosinophil cell surface. Inflammation is an important component in the pathogenesis of asthma, CRSwNP, EGPA, and HES. Multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) are involved in inflammation. By inhibiting IL-5 signaling, Mepolizumab reduces the production and survival of eosinophils; however, the mechanism of mepolizumab action in asthma, CRSwNP, EGPA, and HES has not been definitively established.
<h3>NUCALA Drug Market Report Scope</h3>
The NUCALA Market Forecast Report provides insights into:
<ul>
<li>A comprehensive product overview including the NUCALA description, NUCALA Mechanism of Action, dosage and administration, research and development activities in Nasal Polyposis and Asthma.</li>
<li>Elaborated details on NUCALA regulatory milestones and other development activities have been provided in this report.</li>
<li>The NUCALA Market Size Report also highlights the NUCALA research and development activity in Nasal Polyposis and Asthma details across the United States, Europe, and Japan.</li>
<li>The NUCALA Market Forecast Report also covers the patent information with expiry timeline around NUCALA.</li>
<li>The report contains forecasted NUCALA Sales for Nasal Polyposis and Asthma till 2032.</li>
<li>Comprehensive coverage of the late-stage emerging therapies for Nasal Polyposis and Asthma.</li>
<li>The NUCALA Market Forecast Report also features the SWOT analysis with analyst views for NUCALA in Nasal Polyposis and Asthma</li>
</ul>
<h3>NUCALA Methodology</h3>
The NUCALA Market Size Report is built using data and information sourced primarily from internal databases, primary and secondary research, and in-house analysis by DelveInsight&rsquo;s team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities' websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals, and access to available databases.
<h3>NUCALA Drug Market: Analytical Perspective by DelveInsight</h3>
<ul>
<li>In-depth NUCALA Market Assessment</li>
</ul>
This NUCALA Market Size Report provides a detailed Market assessment of NUCALA in Nasal Polyposis and Asthma in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. This segment of the report provides forecasted NUCALA Sales Data from 2022 to 2032.
<ul>
<li>NUCALA Clinical Trials Assessment</li>
</ul>
The report provides the NUCALA Clinical Trials information of NUCALA for Nasal Polyposis and Asthma, covering trial interventions, trial conditions, trial status, start, and completion dates.
<h3>NUCALA Drug Market Report Highlights&nbsp;</h3>
<ul>
<li>In the coming years, the NUCALA Drug Market scenario for Nasal Polyposis and Asthma is set to change due to the extensive research and incremental healthcare spending across the world, which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.&nbsp;&nbsp;</li>
<li>The NUCALA Companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence NUCALA dominance.</li>
<li>Other emerging products for Nasal Polyposis and Asthma are expected to give tough market competition to NUCALA, and the launch of late-stage emerging therapies shortly will significantly impact the NUCALA Drug Market.</li>
<li>A detailed description of regulatory milestones and developmental activities provides the current development scenario of NUCALA MOA in Nasal Polyposis and Asthma.</li>
<li>Our in-depth analysis of the forecasted NUCALA Sales Data from 2022 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the NUCALA in Nasal Polyposis and Asthma.</li>
<li>Analyze NUCALA Cost, pricing trends, and market positioning to support strategic decision-making in the NUCALA Market Landscape.</li>
</ul>
Key Questions
<ul>
<li>What is the product type, route of administration, and NUCALA Mechanism of Action?</li>
<li>What is the NUCALA Clinical Trials status of the study related to NUCALA in Nasal Polyposis and Asthma, and the study completion date?</li>
<li>What are the key collaborations, mergers and acquisitions, licensing, and other activities related to the NUCALA development?</li>
<li>What are the key designations that have been granted to NUCALA MOA for Nasal Polyposis and Asthma?</li>
<li>What is the forecasted NUCALA Market Scenario for Nasal Polyposis and Asthma?</li>
<li>What are the forecasted NUCALA Sales in the 7MM, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?&nbsp;</li>
<li>What are the other emerging products available in Nasal Polyposis and Asthma, and how are they giving competition to NUCALA for Nasal Polyposis?</li>
<li>Which are the late-stage emerging therapies under development for the treatment of Nasal Polyposis and Asthma? &nbsp;</li>
</ul>
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1. Report Introduction
2. NUCALA Overview
2.1. Product Detail
2.2. Clinical Development
2.2.1. Clinical Studies
2.2.2. Clinical Trials Information
2.2.3. Safety and Efficacy
2.3. Other Development Activities
2.4. Product Profile
3. Competitive Landscape (Marketed Therapies)
4. Competitive Landscape (Late-stage Emerging Therapies)*
5. NUCALA Market Assessment
5.1. Market Outlook of NUCALA&nbsp;
5.2. 7MM Market Analysis
5.2.1. Market Size of NUCALA in the 7MM for Nasal Polyposis and Asthma
5.3. Country-wise Market Analysis
5.3.1. Market Size of NUCALA in the United States for Nasal Polyposis and Asthma
5.3.2. Market Size of NUCALA in Germany for Nasal Polyposis and Asthma
5.3.3. Market Size of NUCALA in France for Nasal Polyposis and Asthma
5.3.4. Market Size of NUCALA in Italy for Nasal Polyposis and Asthma
5.3.5. Market Size of NUCALA in Spain for Nasal Polyposis and Asthma
5.3.6. Market Size of NUCALA in the United Kingdo1m for Nasal Polyposis and Asthma
5.3.7. Market Size of NUCALA in Japan for Nasal Polyposis and Asthma
6. SWOT Analysis
7. Analysts&rsquo; Views
8. Appendix
8.1. Bibliography
8.2. Report Methodology
9. DelveInsight Capabilities
10. Disclaimer
11. About DelveInsight
12. Report Purchase Option &nbsp;

NUCALA Market

NUCALA Market Size, Forecast, and Drug Insight – 2032

NUCALA Drug Insight and Market Forecast- 2032 report by DelveInsight outlays comprehensive insights of the product indicated for the treatment of its approved condition.